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The map label for this gene is thrC [H]

Identifier: 158312860

GI number: 158312860

Start: 1186838

End: 1187962

Strand: Direct

Name: thrC [H]

Synonym: Franean1_1006

Alternate gene names: 158312860

Gene position: 1186838-1187962 (Clockwise)

Preceding gene: 158312859

Following gene: 158312861

Centisome position: 13.21

GC content: 73.16

Gene sequence:

>1125_bases
ATGACCACGATGTCGTCGATGCCGGTTTCGAGCGACCCGGCCGGCAGCAGTGCCCCCGAGCGCGCGTCGCGGGCCTGGCG
GGGGATCATCGAGGAGTACCGGGACCGGCTGCCCGTCACCGCCGACACACCGGTGATCACCCTGCGGGAGGGCGGCACCC
CGCTGCTGCACGCGGACCATCTGTCCGAGCTGACCGGATGTGATGTTCATCTCAAGGTCGAAGGTGCCAACCCCACCGGC
TCGTTCAAGGACCGCGGCATGACGGTCGCGATCAGCCGGGCGGTGGGAGAGGGCTCCCAGGCCGTCATCTGCGCGTCCAC
CGGCAATACCTCGGCCTCGGCCGCGGCGTACGCCGCCCGCGCCGGGCTGACCTGCGCGGTGCTGGTTCCCAGCGGCAAGA
TCGCCCTCGGCAAGCTCGCGCAGGCCCTGGTGCACGGCGCGCGCCTGCTCCAGGTGGAGGGGTCGTTCGACGACTGCCTC
CGGGTCGCCCGCGAGCTGGCCGACACGTTCCCGGTCACGCTGGTGAACTCGGTCAACCCGCACCGCCTGGAGGGGCAGAA
GACCGCCGCCTTCGAGATCGTCGAGGCGCTCGGCCACGCGCCCGACGTGCACTGCCTGCCGGTCGGGAACGCGGGTAACA
TCACCGCCTACTGGCGCGGCTACGTCGAGGAGGACACCCGGATCCGGTCCGGCCGGCCGCGGATGTTCGGGTTCCAGGCG
GCGGGCGCGGCGCCGATCGTGCGGGGCGAGGTGGTGACCTCGCCGCAGACCATCGCCACGGCCATCCGCATCGGCAACCC
GGCCTCCTGGGATTTCGCGACCGACGCGCGGGACGCCTCCGGCGGTCTGATCGACGCGGTCAACGACCGGCAGATCCTGG
CCGCCTACCGGCTGCTGGCGCGCCGCGAGGGCGTCTTCGTCGAGCCGTCCAGTGCCGCCAGCGTCGCCGGGCTGCTCGCC
ACGTACGCCGACGGCCGGCTGAGCCCGGGCCAGCGGGTCGTCTGCACCGTCACCGGCAACGGGCTGAAGGACCCGGACTG
GGCCATCAGCGGCGCGGCGAAGCCCGAGACCATCCCGCCGACCGTGGCCGGCGCCGCCAGGGCCCTCGGCCTGCAGCGGT
CGTGA

Upstream 100 bases:

>100_bases
CGGCCGCGGATGCGGCGCTGTCCACGACCGTCGAGGACCTGCGGGTTCTCGACGGGGTGCGTGCGGTGTCGGGCGTGGTA
CGGGTCGAGGGAGTTGAGTC

Downstream 100 bases:

>100_bases
CGACCGCCGACGGCCTCGCCGCCGGTGCCGCCGGCAGCGCCTCGGGAAGCGGTACGGCCAGCGCGTCGGCGAATGCCTCC
GTCAGCACACGGGTGAGCAC

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MTTMSSMPVSSDPAGSSAPERASRAWRGIIEEYRDRLPVTADTPVITLREGGTPLLHADHLSELTGCDVHLKVEGANPTG
SFKDRGMTVAISRAVGEGSQAVICASTGNTSASAAAYAARAGLTCAVLVPSGKIALGKLAQALVHGARLLQVEGSFDDCL
RVARELADTFPVTLVNSVNPHRLEGQKTAAFEIVEALGHAPDVHCLPVGNAGNITAYWRGYVEEDTRIRSGRPRMFGFQA
AGAAPIVRGEVVTSPQTIATAIRIGNPASWDFATDARDASGGLIDAVNDRQILAAYRLLARREGVFVEPSSAASVAGLLA
TYADGRLSPGQRVVCTVTGNGLKDPDWAISGAAKPETIPPTVAGAARALGLQRS

Sequences:

>Translated_374_residues
MTTMSSMPVSSDPAGSSAPERASRAWRGIIEEYRDRLPVTADTPVITLREGGTPLLHADHLSELTGCDVHLKVEGANPTG
SFKDRGMTVAISRAVGEGSQAVICASTGNTSASAAAYAARAGLTCAVLVPSGKIALGKLAQALVHGARLLQVEGSFDDCL
RVARELADTFPVTLVNSVNPHRLEGQKTAAFEIVEALGHAPDVHCLPVGNAGNITAYWRGYVEEDTRIRSGRPRMFGFQA
AGAAPIVRGEVVTSPQTIATAIRIGNPASWDFATDARDASGGLIDAVNDRQILAAYRLLARREGVFVEPSSAASVAGLLA
TYADGRLSPGQRVVCTVTGNGLKDPDWAISGAAKPETIPPTVAGAARALGLQRS
>Mature_373_residues
TTMSSMPVSSDPAGSSAPERASRAWRGIIEEYRDRLPVTADTPVITLREGGTPLLHADHLSELTGCDVHLKVEGANPTGS
FKDRGMTVAISRAVGEGSQAVICASTGNTSASAAAYAARAGLTCAVLVPSGKIALGKLAQALVHGARLLQVEGSFDDCLR
VARELADTFPVTLVNSVNPHRLEGQKTAAFEIVEALGHAPDVHCLPVGNAGNITAYWRGYVEEDTRIRSGRPRMFGFQAA
GAAPIVRGEVVTSPQTIATAIRIGNPASWDFATDARDASGGLIDAVNDRQILAAYRLLARREGVFVEPSSAASVAGLLAT
YADGRLSPGQRVVCTVTGNGLKDPDWAISGAAKPETIPPTVAGAARALGLQRS

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=322, Percent_Identity=27.0186335403727, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322631, Length=318, Percent_Identity=26.1006289308176, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 38942; Mature: 38811

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTMSSMPVSSDPAGSSAPERASRAWRGIIEEYRDRLPVTADTPVITLREGGTPLLHADH
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEHHH
LSELTGCDVHLKVEGANPTGSFKDRGMTVAISRAVGEGSQAVICASTGNTSASAAAYAAR
HHHHCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHH
AGLTCAVLVPSGKIALGKLAQALVHGARLLQVEGSFDDCLRVARELADTFPVTLVNSVNP
CCCEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCC
HRLEGQKTAAFEIVEALGHAPDVHCLPVGNAGNITAYWRGYVEEDTRIRSGRPRMFGFQA
CCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECEECCCCEECCCCCCEEEEEC
AGAAPIVRGEVVTSPQTIATAIRIGNPASWDFATDARDASGGLIDAVNDRQILAAYRLLA
CCCCCEEECEEECCCHHHEEEEECCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHH
RREGVFVEPSSAASVAGLLATYADGRLSPGQRVVCTVTGNGLKDPDWAISGAAKPETIPP
HCCCCEECCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCEECCCCCCCCCCC
TVAGAARALGLQRS
HHHHHHHHHCCCCC
>Mature Secondary Structure 
TTMSSMPVSSDPAGSSAPERASRAWRGIIEEYRDRLPVTADTPVITLREGGTPLLHADH
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEEHHH
LSELTGCDVHLKVEGANPTGSFKDRGMTVAISRAVGEGSQAVICASTGNTSASAAAYAAR
HHHHCCCEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHH
AGLTCAVLVPSGKIALGKLAQALVHGARLLQVEGSFDDCLRVARELADTFPVTLVNSVNP
CCCEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHCCEEEECCCCC
HRLEGQKTAAFEIVEALGHAPDVHCLPVGNAGNITAYWRGYVEEDTRIRSGRPRMFGFQA
CCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECEECCCCEECCCCCCEEEEEC
AGAAPIVRGEVVTSPQTIATAIRIGNPASWDFATDARDASGGLIDAVNDRQILAAYRLLA
CCCCCEEECEEECCCHHHEEEEECCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHH
RREGVFVEPSSAASVAGLLATYADGRLSPGQRVVCTVTGNGLKDPDWAISGAAKPETIPP
HCCCCEECCCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCEECCCCCCCCCCC
TVAGAARALGLQRS
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA