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The map label for this gene is desR [H]

Identifier: 158312386

GI number: 158312386

Start: 614951

End: 615556

Strand: Direct

Name: desR [H]

Synonym: Franean1_0528

Alternate gene names: 158312386

Gene position: 614951-615556 (Clockwise)

Preceding gene: 158312385

Following gene: 158312390

Centisome position: 6.85

GC content: 74.75

Gene sequence:

>606_bases
ATGATCAAGGTGCTGCTCGCCGATGACGAGAACCTCATCCGCGGCGCGCTGGCGGTGCTGCTGTCCATGGAGGACGACAT
CACGGTGGTCGCGCAGGCGGCATCCGGGCCGGAGGCGCTGGCGACGGCCCGGCTCCACCGCCCCGACGTCGCGCTGCTCG
ACCTGCAGATGCCCGGCCTGGACGGCATTGCCGTCGCCCAGGCGCTGCACGCCGACCTGCCCGCGTGCGCCAACGTGATC
GTGACCAGCCACGGGCGGCCCGGCTATCTCAGGCGGGCGCTCGCCGCCGGAGCGCGCGGCTTCCTGCCCAAGACCGTGTC
CGTGCAGGTGCTCGCCGACGTGGTGCGGGTGGTGCACGGCGGCGGCCGGTACGTGGACCCGGAGCTGGCGGCCGAGGCGA
TCGCGGCCGGGGACAGCCCGCTGACGCCGCGCGAGGCGGAGGTGCTGGAGCTGGCCGCCGGCGGCGCGCCGGTGGAGGAG
ATCGCGGCACGGTTGTCGCTGTCGCGGGGCACCGTGCGCAACTACCTGTCGTCGGCGGTCGCCAAGCTGGGCGCGGTCAA
CCGGCACGAGGCCGTCCAGCTCGCCCGCGTCCGCGGCTGGATCTGA

Upstream 100 bases:

>100_bases
AGGCGCGGCTCCCGGTCCCCGCCGACGCCGCGCACGGCGCGGCCCCGGTCGGGACACCGCCGCCCGCGCGGGGCGCGGCC
ATCGTGCTGGAGGCGGGCTC

Downstream 100 bases:

>100_bases
CCGGAGGCGGCCCCGCGAGGGATCATGCCCGCGCCGGCGGGCCTACTCGCGGACGCCGGCCAGCTCGGCGGGGCGGCGAC
GCAGCAGCAGCGCGGCCGGG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MIKVLLADDENLIRGALAVLLSMEDDITVVAQAASGPEALATARLHRPDVALLDLQMPGLDGIAVAQALHADLPACANVI
VTSHGRPGYLRRALAAGARGFLPKTVSVQVLADVVRVVHGGGRYVDPELAAEAIAAGDSPLTPREAEVLELAAGGAPVEE
IAARLSLSRGTVRNYLSSAVAKLGAVNRHEAVQLARVRGWI

Sequences:

>Translated_201_residues
MIKVLLADDENLIRGALAVLLSMEDDITVVAQAASGPEALATARLHRPDVALLDLQMPGLDGIAVAQALHADLPACANVI
VTSHGRPGYLRRALAAGARGFLPKTVSVQVLADVVRVVHGGGRYVDPELAAEAIAAGDSPLTPREAEVLELAAGGAPVEE
IAARLSLSRGTVRNYLSSAVAKLGAVNRHEAVQLARVRGWI
>Mature_201_residues
MIKVLLADDENLIRGALAVLLSMEDDITVVAQAASGPEALATARLHRPDVALLDLQMPGLDGIAVAQALHADLPACANVI
VTSHGRPGYLRRALAAGARGFLPKTVSVQVLADVVRVVHGGGRYVDPELAAEAIAAGDSPLTPREAEVLELAAGGAPVEE
IAARLSLSRGTVRNYLSSAVAKLGAVNRHEAVQLARVRGWI

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=38.6138613861386, Blast_Score=111, Evalue=3e-26,
Organism=Escherichia coli, GI1788222, Length=206, Percent_Identity=29.126213592233, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788521, Length=195, Percent_Identity=29.7435897435897, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786747, Length=198, Percent_Identity=24.7474747474747, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787473, Length=201, Percent_Identity=32.3383084577114, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788546, Length=195, Percent_Identity=27.6923076923077, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788712, Length=184, Percent_Identity=24.4565217391304, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20892; Mature: 20892

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVLLADDENLIRGALAVLLSMEDDITVVAQAASGPEALATARLHRPDVALLDLQMPGL
CEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEEEECCCC
DGIAVAQALHADLPACANVIVTSHGRPGYLRRALAAGARGFLPKTVSVQVLADVVRVVHG
CHHHHHHHHHCCCHHHHHEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
GGRYVDPELAAEAIAAGDSPLTPREAEVLELAAGGAPVEEIAARLSLSRGTVRNYLSSAV
CCCEECHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHH
AKLGAVNRHEAVQLARVRGWI
HHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKVLLADDENLIRGALAVLLSMEDDITVVAQAASGPEALATARLHRPDVALLDLQMPGL
CEEEEEECCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCCEEEEEEECCCC
DGIAVAQALHADLPACANVIVTSHGRPGYLRRALAAGARGFLPKTVSVQVLADVVRVVHG
CHHHHHHHHHCCCHHHHHEEEECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHC
GGRYVDPELAAEAIAAGDSPLTPREAEVLELAAGGAPVEEIAARLSLSRGTVRNYLSSAV
CCCEECHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHH
AKLGAVNRHEAVQLARVRGWI
HHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]