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The map label for this gene is ygeX [H]

Identifier: 157963891

GI number: 157963891

Start: 4959855

End: 4961033

Strand: Direct

Name: ygeX [H]

Synonym: Spea_4080

Alternate gene names: 157963891

Gene position: 4959855-4961033 (Clockwise)

Preceding gene: 157963890

Following gene: 157963892

Centisome position: 95.85

GC content: 47.24

Gene sequence:

>1179_bases
ATGCTAAAGCTGACTCAAAATGATTTCTTTAACGGCGAGACTTCTGAACTTTTCACTGCTCAAGTCGCTGAACAAACTCG
TCAATTCCACCAGCAGATCGAAGCTTACCAGCCAACACCGCTGGTCTCTTTAGAGCAGCTTGCTGCACGCTTAGGCGTTA
AAGCAATTCTGGTTAAAGACGAATCTTACCGTTTCGGTCTAAACGCTTTTAAAGTACTGGGTGGTTCTTACGCATTAGGT
AAGCAACTTGCTGAGCACTTAAATGTAGATATCAGTGAAATTGATATGAAAACTGTTGCCGCTAAATTAAGCGCGCCATT
GGTTTTCGCTACTGCAACTGCTGGTAACCACGGCACAGGTGTGGCTTGGGCTGCACGTGAAATGGGCCAAAAGGCTGTTG
TTTACATGCCAAAGGGTTCATCTCAAGCGAGTGTGACTCGCATTCAAAACTTAGGTGCTGAGTGTATCGTTACTGACTGT
AACTACGACGACACCGTACGTATTGCTAACCAAACCGCGACTGAAAACGGTTGGATGCTAGTACAAGATACTGCATGGGA
AGGTTACGACAAGATCCCAACTTGGATCTCTCAAGGCTATATGACTATGGCCGTTGAAGCGCAAGAGCAAGTTGAAGCCA
TGGGTCTTAAGCCAACTCACCTAATGCTACAAGCAGGTGTTGGTGCAATGGCTGGCGGTCTATTAGGTTACTTCGCTGAC
AAAGTTGGCGCGACTAACTTCAAGACTATTATTGCTGAGCCTGCAAAAGCAGATTGTATCTACAACTCAGGCATTAAAGG
CGAAATGGTTGCAGTAACTGGCGAGTTAAACTCTATCATGGCAGGCCTTGCATGTGGCGAGCCTAACCCAGTCACTTGGC
CTATCCTTAAGCAATGCAGCAGCTTCTTCGCATCAGTTGAAGATGAAGTAACCGCGACGGGGATGCGCGTTCTTGGTAAC
CCACTAGCGGGTGATACTAAAGTTGTTAGTGGTGAGTCAGGTGCACTAACTCTAGGCCTACTTTACATGCTAGCAAGCCG
TGAAGAGTACAGCGAGTACCGCACGCAGCTTGGCCTAGATCAAGATGCCGTTATCATGCTGTTCAGCACTGAAGGCGACA
CTAACCCAGACCGTTACCGTCAAATCGTTTGGGAAGGCATGCACAGCACTGCTAAATAA

Upstream 100 bases:

>100_bases
TTAGGTTATTAACGACCTATTTAAGTCAATCTGACTGTCCATTTGCCAACATGGGTTAAGTGGACAGCAGTCCTCCTGTT
CAAAATTTATAGTGGTTACC

Downstream 100 bases:

>100_bases
GTTCTTCGAATTTAGATAACAAAAGCCACTTACATAGTGGCTTTTTTGTTATCTAAAAATAGGTTCTAGGTTCTAGGACG
TTCGCAGGCTCACTGCGAGG

Product: diaminopropionate ammonia-lyase

Products: NA

Alternate protein names: Diaminopropionatase; Alpha,beta-diaminopropionate ammonia-lyase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MLKLTQNDFFNGETSELFTAQVAEQTRQFHQQIEAYQPTPLVSLEQLAARLGVKAILVKDESYRFGLNAFKVLGGSYALG
KQLAEHLNVDISEIDMKTVAAKLSAPLVFATATAGNHGTGVAWAAREMGQKAVVYMPKGSSQASVTRIQNLGAECIVTDC
NYDDTVRIANQTATENGWMLVQDTAWEGYDKIPTWISQGYMTMAVEAQEQVEAMGLKPTHLMLQAGVGAMAGGLLGYFAD
KVGATNFKTIIAEPAKADCIYNSGIKGEMVAVTGELNSIMAGLACGEPNPVTWPILKQCSSFFASVEDEVTATGMRVLGN
PLAGDTKVVSGESGALTLGLLYMLASREEYSEYRTQLGLDQDAVIMLFSTEGDTNPDRYRQIVWEGMHSTAK

Sequences:

>Translated_392_residues
MLKLTQNDFFNGETSELFTAQVAEQTRQFHQQIEAYQPTPLVSLEQLAARLGVKAILVKDESYRFGLNAFKVLGGSYALG
KQLAEHLNVDISEIDMKTVAAKLSAPLVFATATAGNHGTGVAWAAREMGQKAVVYMPKGSSQASVTRIQNLGAECIVTDC
NYDDTVRIANQTATENGWMLVQDTAWEGYDKIPTWISQGYMTMAVEAQEQVEAMGLKPTHLMLQAGVGAMAGGLLGYFAD
KVGATNFKTIIAEPAKADCIYNSGIKGEMVAVTGELNSIMAGLACGEPNPVTWPILKQCSSFFASVEDEVTATGMRVLGN
PLAGDTKVVSGESGALTLGLLYMLASREEYSEYRTQLGLDQDAVIMLFSTEGDTNPDRYRQIVWEGMHSTAK
>Mature_392_residues
MLKLTQNDFFNGETSELFTAQVAEQTRQFHQQIEAYQPTPLVSLEQLAARLGVKAILVKDESYRFGLNAFKVLGGSYALG
KQLAEHLNVDISEIDMKTVAAKLSAPLVFATATAGNHGTGVAWAAREMGQKAVVYMPKGSSQASVTRIQNLGAECIVTDC
NYDDTVRIANQTATENGWMLVQDTAWEGYDKIPTWISQGYMTMAVEAQEQVEAMGLKPTHLMLQAGVGAMAGGLLGYFAD
KVGATNFKTIIAEPAKADCIYNSGIKGEMVAVTGELNSIMAGLACGEPNPVTWPILKQCSSFFASVEDEVTATGMRVLGN
PLAGDTKVVSGESGALTLGLLYMLASREEYSEYRTQLGLDQDAVIMLFSTEGDTNPDRYRQIVWEGMHSTAK

Specific function: Catalyzes the alpha,beta-elimination reaction of both L- and D-alpha,beta-diaminopropionate, the most suitable substrates to form pyruvate and ammonia. The L- and D-isomers of serine are also degraded, though slowly; it is the only serine dehydratase whic

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789235, Length=390, Percent_Identity=56.4102564102564, Blast_Score=473, Evalue=1e-134,
Organism=Escherichia coli, GI1790207, Length=177, Percent_Identity=30.5084745762712, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010081
- InterPro:   IPR019871
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.15 [H]

Molecular weight: Translated: 42361; Mature: 42361

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLTQNDFFNGETSELFTAQVAEQTRQFHQQIEAYQPTPLVSLEQLAARLGVKAILVKD
CCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEEEEC
ESYRFGLNAFKVLGGSYALGKQLAEHLNVDISEIDMKTVAAKLSAPLVFATATAGNHGTG
CCCEECCHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
VAWAAREMGQKAVVYMPKGSSQASVTRIQNLGAECIVTDCNYDDTVRIANQTATENGWML
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCCCEEE
VQDTAWEGYDKIPTWISQGYMTMAVEAQEQVEAMGLKPTHLMLQAGVGAMAGGLLGYFAD
EEECCCCCCHHHHHHHHCCEEEEEEEHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHH
KVGATNFKTIIAEPAKADCIYNSGIKGEMVAVTGELNSIMAGLACGEPNPVTWPILKQCS
HCCCCCCHHEEECCCCCCEEECCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCHHHHHHH
SFFASVEDEVTATGMRVLGNPLAGDTKVVSGESGALTLGLLYMLASREEYSEYRTQLGLD
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
QDAVIMLFSTEGDTNPDRYRQIVWEGMHSTAK
CCEEEEEEECCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKLTQNDFFNGETSELFTAQVAEQTRQFHQQIEAYQPTPLVSLEQLAARLGVKAILVKD
CCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEEEEC
ESYRFGLNAFKVLGGSYALGKQLAEHLNVDISEIDMKTVAAKLSAPLVFATATAGNHGTG
CCCEECCHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCC
VAWAAREMGQKAVVYMPKGSSQASVTRIQNLGAECIVTDCNYDDTVRIANQTATENGWML
HHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCCCEEE
VQDTAWEGYDKIPTWISQGYMTMAVEAQEQVEAMGLKPTHLMLQAGVGAMAGGLLGYFAD
EEECCCCCCHHHHHHHHCCEEEEEEEHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHH
KVGATNFKTIIAEPAKADCIYNSGIKGEMVAVTGELNSIMAGLACGEPNPVTWPILKQCS
HCCCCCCHHEEECCCCCCEEECCCCCCEEEEEECCHHHHHHHHCCCCCCCCCCHHHHHHH
SFFASVEDEVTATGMRVLGNPLAGDTKVVSGESGALTLGLLYMLASREEYSEYRTQLGLD
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
QDAVIMLFSTEGDTNPDRYRQIVWEGMHSTAK
CCEEEEEEECCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]