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The map label for this gene is menC [H]

Identifier: 157963784

GI number: 157963784

Start: 4827341

End: 4828414

Strand: Direct

Name: menC [H]

Synonym: Spea_3973

Alternate gene names: 157963784

Gene position: 4827341-4828414 (Clockwise)

Preceding gene: 157963783

Following gene: 157963785

Centisome position: 93.29

GC content: 48.88

Gene sequence:

>1074_bases
ATGACAACGACGCAACAGCAAGCAACGCCATTTACTCTAACGCACATAAGCCTGCATCAGTTTACTATCGATTTAGATAA
ACCTTTACCCGTTGGAAAACAGCGCATCGAAAAGCGCAGTGGCTTAGTACTCTCGGCAACCGCCAGCAATAATATGCTTC
AGCGCCAAGCCTGTGTCGAGATCTCGCCGCTTTCAGGCTTAGATAATCAAGGCCAAACCTTAATAGGTTTTAGCCGCGAG
ACACTAGCCGAAGTCGCTGAGCAGTTAACGGCATTATTGCCACAATTACACCAGCAACCGAGTGACAACTTGCTCGCGTT
GGCAGAGCAAACACCTTATCCATCACTCGCCTTCGGCCTTAGCCAACTGCATGGAAAACTCGCAGGCAAGTTCAACGGCC
ATAGCATTACCCCGCGCACTGTTCCGCTCATTTATCGCCAAAGCGGTGAACCACTCACCGCCGTAGCCGATCGCGTAAGC
AGCTTGCCCAGCAGCGTTTATGCCGTGAAGGTAAAAGTTGCCCAAGACTCACTTGAAGATGAGATTAAACTAATTCATCA
GATCTTAGCCATTCGCCCCAATCTAAAACTACGTTTAGATGCCAATCGCGGCTTTAGCCTAGAACAAGCCATAGAATTCG
CCGCCTGCTTACCGCTAGATAGCATTGAGTACATAGAAGAGCCTTGCCACAACCCCGATGACAATCAGGATTTTTACCAC
GCGATAGCCATGCCTTGGGCACTAGATGAGACCCTCAACGATCCAACATACCAGTTTGAGCTGCAGCCAGGATTACGAGC
ACTGATTATCAAACCGACTCTATTAGGCAGTATCGAAAAGCTGCAGCATCTAATTGAGACGGCAGAGGAACATGGCGTAC
GCTGCATTCTAAGTTCAAGTTTAGAAGCAAGCCTTGGGATTGAGGCGATAAGTCGCTTAGCGCAAATGATGACTCCAGAT
GAGATCCCGGGAGTTGATACACTGGGCGCCTTTAGCCAAGATTTAGTGGTGAGTTCAGGCAAGGAACACAGCTTAAGCCT
TGAGGAGTTAACGCCACTAATCAGCCTAAGCTAG

Upstream 100 bases:

>100_bases
GCACCGCAAGCATTCGCCATTAAATTGCGCGCGCTTTTCAGTTAGCATATATTCGCTAGAACTCATTACTGATATAACAA
ATAACCATGCAGGCAGGCCA

Downstream 100 bases:

>100_bases
TCAAAACCAGATTAGAACTAATCCTTGGTCAGTGTTAGTTTGGCTCAATCAAAAAGATAAATTCGATAACGGATCTCAGC
ATGCAAGCTCAGGCAATATC

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MTTTQQQATPFTLTHISLHQFTIDLDKPLPVGKQRIEKRSGLVLSATASNNMLQRQACVEISPLSGLDNQGQTLIGFSRE
TLAEVAEQLTALLPQLHQQPSDNLLALAEQTPYPSLAFGLSQLHGKLAGKFNGHSITPRTVPLIYRQSGEPLTAVADRVS
SLPSSVYAVKVKVAQDSLEDEIKLIHQILAIRPNLKLRLDANRGFSLEQAIEFAACLPLDSIEYIEEPCHNPDDNQDFYH
AIAMPWALDETLNDPTYQFELQPGLRALIIKPTLLGSIEKLQHLIETAEEHGVRCILSSSLEASLGIEAISRLAQMMTPD
EIPGVDTLGAFSQDLVVSSGKEHSLSLEELTPLISLS

Sequences:

>Translated_357_residues
MTTTQQQATPFTLTHISLHQFTIDLDKPLPVGKQRIEKRSGLVLSATASNNMLQRQACVEISPLSGLDNQGQTLIGFSRE
TLAEVAEQLTALLPQLHQQPSDNLLALAEQTPYPSLAFGLSQLHGKLAGKFNGHSITPRTVPLIYRQSGEPLTAVADRVS
SLPSSVYAVKVKVAQDSLEDEIKLIHQILAIRPNLKLRLDANRGFSLEQAIEFAACLPLDSIEYIEEPCHNPDDNQDFYH
AIAMPWALDETLNDPTYQFELQPGLRALIIKPTLLGSIEKLQHLIETAEEHGVRCILSSSLEASLGIEAISRLAQMMTPD
EIPGVDTLGAFSQDLVVSSGKEHSLSLEELTPLISLS
>Mature_356_residues
TTTQQQATPFTLTHISLHQFTIDLDKPLPVGKQRIEKRSGLVLSATASNNMLQRQACVEISPLSGLDNQGQTLIGFSRET
LAEVAEQLTALLPQLHQQPSDNLLALAEQTPYPSLAFGLSQLHGKLAGKFNGHSITPRTVPLIYRQSGEPLTAVADRVSS
LPSSVYAVKVKVAQDSLEDEIKLIHQILAIRPNLKLRLDANRGFSLEQAIEFAACLPLDSIEYIEEPCHNPDDNQDFYHA
IAMPWALDETLNDPTYQFELQPGLRALIIKPTLLGSIEKLQHLIETAEEHGVRCILSSSLEASLGIEAISRLAQMMTPDE
IPGVDTLGAFSQDLVVSSGKEHSLSLEELTPLISLS

Specific function: Converts SHCHC to OSB [H]

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788596, Length=315, Percent_Identity=32.0634920634921, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 39105; Mature: 38974

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00626 RCC1_2 ; PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTQQQATPFTLTHISLHQFTIDLDKPLPVGKQRIEKRSGLVLSATASNNMLQRQACVE
CCCCCCCCCCEEEEEEEEEEEEEECCCCCCCCHHHHHHHCCEEEEECCCCCHHHHHHHCE
ISPLSGLDNQGQTLIGFSRETLAEVAEQLTALLPQLHQQPSDNLLALAEQTPYPSLAFGL
ECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHH
SQLHGKLAGKFNGHSITPRTVPLIYRQSGEPLTAVADRVSSLPSSVYAVKVKVAQDSLED
HHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEEHHHHHHH
EIKLIHQILAIRPNLKLRLDANRGFSLEQAIEFAACLPLDSIEYIEEPCHNPDDNQDFYH
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHH
AIAMPWALDETLNDPTYQFELQPGLRALIIKPTLLGSIEKLQHLIETAEEHGVRCILSSS
HHHCCHHHHHHCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCEEEEECCC
LEASLGIEAISRLAQMMTPDEIPGVDTLGAFSQDLVVSSGKEHSLSLEELTPLISLS
CHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCHHHCCC
>Mature Secondary Structure 
TTTQQQATPFTLTHISLHQFTIDLDKPLPVGKQRIEKRSGLVLSATASNNMLQRQACVE
CCCCCCCCCEEEEEEEEEEEEEECCCCCCCCHHHHHHHCCEEEEECCCCCHHHHHHHCE
ISPLSGLDNQGQTLIGFSRETLAEVAEQLTALLPQLHQQPSDNLLALAEQTPYPSLAFGL
ECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHH
SQLHGKLAGKFNGHSITPRTVPLIYRQSGEPLTAVADRVSSLPSSVYAVKVKVAQDSLED
HHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEEEHHHHHHH
EIKLIHQILAIRPNLKLRLDANRGFSLEQAIEFAACLPLDSIEYIEEPCHNPDDNQDFYH
HHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHH
AIAMPWALDETLNDPTYQFELQPGLRALIIKPTLLGSIEKLQHLIETAEEHGVRCILSSS
HHHCCHHHHHHCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCEEEEECCC
LEASLGIEAISRLAQMMTPDEIPGVDTLGAFSQDLVVSSGKEHSLSLEELTPLISLS
CHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]