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The map label for this gene is appC [H]

Identifier: 157963454

GI number: 157963454

Start: 4430009

End: 4430839

Strand: Reverse

Name: appC [H]

Synonym: Spea_3642

Alternate gene names: 157963454

Gene position: 4430839-4430009 (Counterclockwise)

Preceding gene: 157963455

Following gene: 157963453

Centisome position: 85.63

GC content: 52.59

Gene sequence:

>831_bases
ATGTATAAAGCCCTACGCCAACCGAGTTTTATCTTGGCTAGTCTCAGCTTGTTAAGCTTAGTGATATTAGCCTTTTTCTG
GCCTTGGTTGGGGGATGAACTCAACCTTCTCAATAAATACCAGGCTCCCTCGATAGCTTACCCCTTTGGCACTGACTGGC
TAGGGCGAGATCTGTTTAGCCGCAGCTTACAGGCACTGGCGCAGAGCATTTATGTGGGGGGCCTTGCCGTGCTGATGAGT
AGCCTTTTGTCACTGGCAATGGCGATGTTTGCCATGTTGCACCCCTATTGCCGTTGGGTGGTCGACTTGCTGGTGGATCT
GTTTATGTCGCTGCCGCACCTGCTGCTACTGATCTTATTTTCGCTAGTGTTTGGTGGTGCAGAGGGGGGCTTAGTGATCG
CCATTGCCCTGAGCCACTGGCCAAAGCTCACGCGGCTGCTGCGTTTCGAGATGCAGCAAGTGCAATCGACCCCCTACTAC
CGCCTCGCTGAGCAGTTTGGCTGCAAGCCATGGCAGCGACTACGAACACATATGCTGCCGCATATTCTGCCTCAATGGTG
GATTGGCGGCTTACTGTTATTTCCCCATGCATTGACTCATATGGCAGCCTTAACCTTTTTAGGCTTTGGGTTAAATCCTG
ATAATCCCTCTATGGGGGCGCTGTTAGCGCAGGCCAGCCAGTATGTGTTAACTGGTCATTGGTGGCTGGGTGTATGCCCG
GGGCTAATGCTACTCGTTTGCTTATTGCTGCTGTCTTTTATTGCCCAGCGTTTGTTAGTCGCGCTGCGCCAGGGGCCGCA
GACTCATGTTAAAGGAGAGGCGTCATGCTGA

Upstream 100 bases:

>100_bases
GCTTTATTAATGGGCTGCACGTTAATATCTGCGCTATTGGTATTTAGTGGCAACCTGATCGCTAACCTACTGTCAGGTTA
TTTTATGCTAGAGGCTAATG

Downstream 100 bases:

>100_bases
CCGTCGATAGACTCAGTATTGCATCGAACGATATCTGTTTATTATCCCCCTTGAGCTTCTCGGTCGCTAAGGGCGAAGTG
CTTGGGGTGGTGGGCGCCAG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MYKALRQPSFILASLSLLSLVILAFFWPWLGDELNLLNKYQAPSIAYPFGTDWLGRDLFSRSLQALAQSIYVGGLAVLMS
SLLSLAMAMFAMLHPYCRWVVDLLVDLFMSLPHLLLLILFSLVFGGAEGGLVIAIALSHWPKLTRLLRFEMQQVQSTPYY
RLAEQFGCKPWQRLRTHMLPHILPQWWIGGLLLFPHALTHMAALTFLGFGLNPDNPSMGALLAQASQYVLTGHWWLGVCP
GLMLLVCLLLLSFIAQRLLVALRQGPQTHVKGEASC

Sequences:

>Translated_276_residues
MYKALRQPSFILASLSLLSLVILAFFWPWLGDELNLLNKYQAPSIAYPFGTDWLGRDLFSRSLQALAQSIYVGGLAVLMS
SLLSLAMAMFAMLHPYCRWVVDLLVDLFMSLPHLLLLILFSLVFGGAEGGLVIAIALSHWPKLTRLLRFEMQQVQSTPYY
RLAEQFGCKPWQRLRTHMLPHILPQWWIGGLLLFPHALTHMAALTFLGFGLNPDNPSMGALLAQASQYVLTGHWWLGVCP
GLMLLVCLLLLSFIAQRLLVALRQGPQTHVKGEASC
>Mature_276_residues
MYKALRQPSFILASLSLLSLVILAFFWPWLGDELNLLNKYQAPSIAYPFGTDWLGRDLFSRSLQALAQSIYVGGLAVLMS
SLLSLAMAMFAMLHPYCRWVVDLLVDLFMSLPHLLLLILFSLVFGGAEGGLVIAIALSHWPKLTRLLRFEMQQVQSTPYY
RLAEQFGCKPWQRLRTHMLPHILPQWWIGGLLLFPHALTHMAALTFLGFGLNPDNPSMGALLAQASQYVLTGHWWLGVCP
GLMLLVCLLLLSFIAQRLLVALRQGPQTHVKGEASC

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=246, Percent_Identity=28.4552845528455, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787054, Length=276, Percent_Identity=26.4492753623188, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789889, Length=264, Percent_Identity=24.2424242424242, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788505, Length=222, Percent_Identity=29.7297297297297, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789964, Length=226, Percent_Identity=27.8761061946903, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30946; Mature: 30946

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]