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The map label for this gene is caiT [H]

Identifier: 157963064

GI number: 157963064

Start: 3982544

End: 3984142

Strand: Reverse

Name: caiT [H]

Synonym: Spea_3247

Alternate gene names: 157963064

Gene position: 3984142-3982544 (Counterclockwise)

Preceding gene: 157963065

Following gene: 157963063

Centisome position: 76.99

GC content: 46.15

Gene sequence:

>1599_bases
ATGAATTTCAAAAATCTCGATCATAAGCTGTTTTGGCCTGCTATCTGCTTCACCTTTTTAAGCTTGGCCTTGGCGGTATT
TTTTCCTGAAAGCTCTAAAGAGGTCGCCCATGCGGGCATGAAGTGGGTGACCAATGATATTGGCTGGTTTATCCAATTAG
CCGGTTTTGGTGCACTTGTATTTTTGATGTGGATTGCTTTTAGTCGTTTTGGTCATATCAAGTTAGGTGACGATAACGAT
GCTCCTGAGTTCACCTATGCCACTTATGCGTTTTTGATCTTTACTGCGGGTGTGGGCGCGGCACTTATTTTTTGGGCCGT
TGGCGAGCCTATGTACTACATGCAGAGCCCACCTATGTTTACTGAGGCGGGCAGTGCTGAGGCTTCTCAGTGGCTTATTA
CTTACACCTTGTTCCATTGGGGACCGATAGGCTGGGCGATCTTCTGTTTGCCTGCAGTTCCATATGCTTATTACCTACAT
AAGAAAAAGAAACGTAACCTGCGTCTATCTAACTTACTTGAGGATGTGATTGGTAAGAAAAATGCCGATGGTCCACTTGG
CTATTTCATCAACATTATCGCCATTTTCGGTACCCTAGGCGCCTTCTCAACTTCAATGGGCTTAGCCGTTGACCTTATCG
GTTCGGGCATTGAGAAAGTCACCGGTTTACCAAATGATATCTGGCTTCAGGTCGGTCTGATTGTACTGTTTATTGTCTTC
TATGCCGTGGTGATGTTGGCCGGTATGAAGAAGGGCGTTGCTAAGCTTGCTAACTGGTGTGTCTATGCCGCGTTCGCTTT
AGGTATTTTCATCTTATTGTCGGGGCCAACCGCGTTTATTCTGTCTTACTTCTTCGACAGCTTGAGCGTGATGGTCGATA
ACTTCGTGCGCATGAGTTTCTGGAGCGATCCAGTTGAAAAGTCTGGTTTCCCACAGGCGTGGACCATGTATTACTGGGCT
TGGTATTTTGCTTACCTAGTGATGATGGGCATCTTCTTAGCGCGTATCTCTAAGGGACGTACGATTAAAGAGTTAGTGTT
AACGACGATTTTCTTTGGCTCGGCAGGTTGTGCCTTCTTTATCGCTATCTTCGGCAGCTACTCGGTATTTAGTGAGTTAA
CGGGTGCACTACCAGTGCTTGAGTGGATGAATGAGGCAGGGGTTTCCATGGCCGTGATTGAGGTGATCAATGCGCTGCCT
TTTGGCGCGGCGATTTTGATTATCTTCCTTATCGTTGAATTCTTCTTAATGTCGACCACTATGACATCGGCTGCCGTGGC
AATCTCGATGATGACCACCAAAGAGTTGGATGCGGATGCGGATCCGGATGTTTCGGTAAGATTGATTTGGGCATTAGGTA
TTGGCGCGGTTTCAATGGCGGCCTTCTTTATGGGGGGCAGTATCGATACGATTAAGTCCATGTGTATTATCGTTGGCTTG
CCGATGATTTTCCTAAATATTTTGATGGTGGTGTGCTTGATGAAGTGGATTAGAAAGGACCACCCAGAACTGTTCAAATC
AACAGTTACACAGGCTGCAAAAAACAACGCAGAACAGGCTGAGCCTGCTCAAGCTGAATTAGCAAAAGTTGAGGGATAA

Upstream 100 bases:

>100_bases
AACCCAATATAACTCGCCGCATCGATTATGCTAACAGCATAAGGCGGCATCAAGCTTGCTCCTTAAATAATAACAAAAAG
GGGCAGCGTGGAATTTACCT

Downstream 100 bases:

>100_bases
CGAGATGGGCGCAAATATTGTTTCGGTTGAATTTATTCCGGTAAACGTGGCGGCGACTAACTGGAGCGAAAACACCGTTA
TCGTTAAGGTTACCGATGAA

Product: BCCT transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MNFKNLDHKLFWPAICFTFLSLALAVFFPESSKEVAHAGMKWVTNDIGWFIQLAGFGALVFLMWIAFSRFGHIKLGDDND
APEFTYATYAFLIFTAGVGAALIFWAVGEPMYYMQSPPMFTEAGSAEASQWLITYTLFHWGPIGWAIFCLPAVPYAYYLH
KKKKRNLRLSNLLEDVIGKKNADGPLGYFINIIAIFGTLGAFSTSMGLAVDLIGSGIEKVTGLPNDIWLQVGLIVLFIVF
YAVVMLAGMKKGVAKLANWCVYAAFALGIFILLSGPTAFILSYFFDSLSVMVDNFVRMSFWSDPVEKSGFPQAWTMYYWA
WYFAYLVMMGIFLARISKGRTIKELVLTTIFFGSAGCAFFIAIFGSYSVFSELTGALPVLEWMNEAGVSMAVIEVINALP
FGAAILIIFLIVEFFLMSTTMTSAAVAISMMTTKELDADADPDVSVRLIWALGIGAVSMAAFFMGGSIDTIKSMCIIVGL
PMIFLNILMVVCLMKWIRKDHPELFKSTVTQAAKNNAEQAEPAQAELAKVEG

Sequences:

>Translated_532_residues
MNFKNLDHKLFWPAICFTFLSLALAVFFPESSKEVAHAGMKWVTNDIGWFIQLAGFGALVFLMWIAFSRFGHIKLGDDND
APEFTYATYAFLIFTAGVGAALIFWAVGEPMYYMQSPPMFTEAGSAEASQWLITYTLFHWGPIGWAIFCLPAVPYAYYLH
KKKKRNLRLSNLLEDVIGKKNADGPLGYFINIIAIFGTLGAFSTSMGLAVDLIGSGIEKVTGLPNDIWLQVGLIVLFIVF
YAVVMLAGMKKGVAKLANWCVYAAFALGIFILLSGPTAFILSYFFDSLSVMVDNFVRMSFWSDPVEKSGFPQAWTMYYWA
WYFAYLVMMGIFLARISKGRTIKELVLTTIFFGSAGCAFFIAIFGSYSVFSELTGALPVLEWMNEAGVSMAVIEVINALP
FGAAILIIFLIVEFFLMSTTMTSAAVAISMMTTKELDADADPDVSVRLIWALGIGAVSMAAFFMGGSIDTIKSMCIIVGL
PMIFLNILMVVCLMKWIRKDHPELFKSTVTQAAKNNAEQAEPAQAELAKVEG
>Mature_532_residues
MNFKNLDHKLFWPAICFTFLSLALAVFFPESSKEVAHAGMKWVTNDIGWFIQLAGFGALVFLMWIAFSRFGHIKLGDDND
APEFTYATYAFLIFTAGVGAALIFWAVGEPMYYMQSPPMFTEAGSAEASQWLITYTLFHWGPIGWAIFCLPAVPYAYYLH
KKKKRNLRLSNLLEDVIGKKNADGPLGYFINIIAIFGTLGAFSTSMGLAVDLIGSGIEKVTGLPNDIWLQVGLIVLFIVF
YAVVMLAGMKKGVAKLANWCVYAAFALGIFILLSGPTAFILSYFFDSLSVMVDNFVRMSFWSDPVEKSGFPQAWTMYYWA
WYFAYLVMMGIFLARISKGRTIKELVLTTIFFGSAGCAFFIAIFGSYSVFSELTGALPVLEWMNEAGVSMAVIEVINALP
FGAAILIIFLIVEFFLMSTTMTSAAVAISMMTTKELDADADPDVSVRLIWALGIGAVSMAAFFMGGSIDTIKSMCIIVGL
PMIFLNILMVVCLMKWIRKDHPELFKSTVTQAAKNNAEQAEPAQAELAKVEG

Specific function: Catalyzes the exchange of L-carnitine for gamma- butyrobetaine and related betaines [H]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family. CaiT subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788102, Length=447, Percent_Identity=28.1879194630872, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1786224, Length=490, Percent_Identity=29.7959183673469, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1786506, Length=471, Percent_Identity=28.4501061571125, Blast_Score=202, Evalue=6e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 58788; Mature: 58788

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA