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The map label for this gene is pgl [H]

Identifier: 157962155

GI number: 157962155

Start: 2843193

End: 2843897

Strand: Reverse

Name: pgl [H]

Synonym: Spea_2334

Alternate gene names: 157962155

Gene position: 2843897-2843193 (Counterclockwise)

Preceding gene: 157962156

Following gene: 157962154

Centisome position: 54.96

GC content: 44.96

Gene sequence:

>705_bases
ATGATTAAAGAAACTGTTTTCAAATCGTTCGATAATAAAGAGGCGTTAGAAGCGCAACTGGCCGAGCGTATTGCTAATCA
ACTGCAAGACGCTGTTGATGCCCGCGGAAAGGCAAGCCTGATTGTTTCTGGCGGCTCTACTCCGCTTAAGTTGTTTGAAC
TACTTAGCAAGAAAGCGATCGACTGGAGTGATGTGTTTATCACGTTAGCCGATGAACGCTGGGTCAGCCCTGAGCACGGT
GATTCTAATGAGCGTTTGGTAAGAAATAACTTACTCAAGAATAGAGCCGCCAGTGCTAAATTTCGTGGTTTGAAGAATAT
GTATTCTTCACCAGAAGAAGGTTGTGCTATGGCAATTGAGCAACTTGGTAGCTTTCCAACGCCTTTTGACGTTGTCGTAT
TAGGCATGGGCAATGATGGGCATACCTGCTCATGGTTCCCTTGTGCTGCAGATGCTGAACTTGATAACGCATTAACATCG
GCTGAATTGTGTGTTGCGGTTACACCTGGCAATGCACCTCATTCACGGATCTCTTTATCAAAGTCAGCTATTTTAGCCAG
CCGTCAAATCTATCTACATATCGTTGGTGAACAAAAACTTGAGGTTTACCGACAAGCACTAGCAAGCGAAGACACGCGTG
AAATGCCAATTCGAGCCGTTCTCGAACAGCATAAAACACCTGTTGATGTTTACTGGAGCGCTTAA

Upstream 100 bases:

>100_bases
GAAACGCCAAAGCCTTACCCTGCTGGCACATGGGGCCCAGTCGCCTCTGTTGCGCTTATCACTAAAGATGGCCGTTCTTG
GGACGAGTAAGGGGAAGACA

Downstream 100 bases:

>100_bases
GGAGTAATTATGCACAGCGTTGTACAATCTGTTACTGACAGAATTATTGAACGAAGCAAAGATTCTCGCGCTAAGTATTT
AGCGGCGCTCGATGATGCTA

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MIKETVFKSFDNKEALEAQLAERIANQLQDAVDARGKASLIVSGGSTPLKLFELLSKKAIDWSDVFITLADERWVSPEHG
DSNERLVRNNLLKNRAASAKFRGLKNMYSSPEEGCAMAIEQLGSFPTPFDVVVLGMGNDGHTCSWFPCAADAELDNALTS
AELCVAVTPGNAPHSRISLSKSAILASRQIYLHIVGEQKLEVYRQALASEDTREMPIRAVLEQHKTPVDVYWSA

Sequences:

>Translated_234_residues
MIKETVFKSFDNKEALEAQLAERIANQLQDAVDARGKASLIVSGGSTPLKLFELLSKKAIDWSDVFITLADERWVSPEHG
DSNERLVRNNLLKNRAASAKFRGLKNMYSSPEEGCAMAIEQLGSFPTPFDVVVLGMGNDGHTCSWFPCAADAELDNALTS
AELCVAVTPGNAPHSRISLSKSAILASRQIYLHIVGEQKLEVYRQALASEDTREMPIRAVLEQHKTPVDVYWSA
>Mature_234_residues
MIKETVFKSFDNKEALEAQLAERIANQLQDAVDARGKASLIVSGGSTPLKLFELLSKKAIDWSDVFITLADERWVSPEHG
DSNERLVRNNLLKNRAASAKFRGLKNMYSSPEEGCAMAIEQLGSFPTPFDVVVLGMGNDGHTCSWFPCAADAELDNALTS
AELCVAVTPGNAPHSRISLSKSAILASRQIYLHIVGEQKLEVYRQALASEDTREMPIRAVLEQHKTPVDVYWSA

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=219, Percent_Identity=27.8538812785388, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 25734; Mature: 25734

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKETVFKSFDNKEALEAQLAERIANQLQDAVDARGKASLIVSGGSTPLKLFELLSKKAI
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCC
DWSDVFITLADERWVSPEHGDSNERLVRNNLLKNRAASAKFRGLKNMYSSPEEGCAMAIE
CCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QLGSFPTPFDVVVLGMGNDGHTCSWFPCAADAELDNALTSAELCVAVTPGNAPHSRISLS
HHCCCCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHCCCEEEEEECCCCCCCHHHHHH
KSAILASRQIYLHIVGEQKLEVYRQALASEDTREMPIRAVLEQHKTPVDVYWSA
HHHHHHHCEEEEEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEECC
>Mature Secondary Structure
MIKETVFKSFDNKEALEAQLAERIANQLQDAVDARGKASLIVSGGSTPLKLFELLSKKAI
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCC
DWSDVFITLADERWVSPEHGDSNERLVRNNLLKNRAASAKFRGLKNMYSSPEEGCAMAIE
CCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QLGSFPTPFDVVVLGMGNDGHTCSWFPCAADAELDNALTSAELCVAVTPGNAPHSRISLS
HHCCCCCCCCEEEEEECCCCCEEEEECCCCCCHHHHHHCCCEEEEEECCCCCCCHHHHHH
KSAILASRQIYLHIVGEQKLEVYRQALASEDTREMPIRAVLEQHKTPVDVYWSA
HHHHHHHCEEEEEEECHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]