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The map label for this gene is asnC [H]

Identifier: 157961855

GI number: 157961855

Start: 2461238

End: 2462638

Strand: Reverse

Name: asnC [H]

Synonym: Spea_2034

Alternate gene names: 157961855

Gene position: 2462638-2461238 (Counterclockwise)

Preceding gene: 157961857

Following gene: 157961854

Centisome position: 47.59

GC content: 45.4

Gene sequence:

>1401_bases
ATGAGCATTACATCTGTCGCTTCTGTGTTTAAAGGTGACTTTGCGATTGGTTCGCAAATCACAGTGCGTGGCTGGGTAAG
ATCCCGTCGCGATTCTAAAGCTGGGATCTCATTCCTAGCTGTTTATGATGGTTCATGTTTTGACCCTATTCAGGGCGTTG
TGCCAAATAATCTAGAGAATTACACCAACGAAGTGTTAAAGCTTACTGCTGGTTGCTCTGTTGTTATGACAGGTGAAGTA
GTTGAATCTCCAGGCCAAGGCCAAGCATTCGAGATGCAAGTCACTAAGGTTGAGGTTGCTGGTTTGGTTGAAGATCCAGA
CACATACCCAATGGCGGCTAAGCGTCACTCAATTGAGCACTTGCGTGAACTTGCTCACCTGCGTCCTCGTACCAATATTA
TTGGTGCAGTCGCACGTGTTCGTAACTGTTTATCTCAAGCAATTCATCGCTTTTACAATGAGCAAGGTTACATTTGGGTT
TCAACGCCACTTATCACGGCTTCAGACACTGAAGGCGCTGGTGAAATGTTCCGAGTTTCGACTCTAGATCTTGAGAACCT
GCCACGTACAGATAAAGGCACTGTGGATTACGCTGAAGATTTCTTTGGTAAAGAATCTTTCCTAACCGTGTCTGGCCAGC
TAAACGCTGAGACTTATGCCTGTGCATTATCAAAAGTTTATACTTTTGGTCCTACATTCCGTGCAGAGAACTCAAACACC
AGCCGTCACTTAGCAGAATTCTGGATGGTTGAGCCTGAAGTTGCCTTCGCCAATCTAGATGATGCGGCTAAGCTTGCTGA
AGATATGCTGAAGTATTGCTTTAAAGCGGTACTGGAAGAACGTCGTGATGATTTAGAGTTCTTCGCTCAACGTGTTGAGA
AAACAGCAATCGAGCGTTTAGAAAACTTCGTTACCAGTGACTTTGCACAAATCGATTACACCGATGCTATCGAAATCCTT
AAAGCTTGCGATAAAGACTTTGAGTACGACGTTGAATGGGGTATCGATCTACACTCAGAGCACGAGCGTTACCTTGCTGA
AGAACACTTCAAAGCGCCAGTTGTTGTGAAGAATTATCCGAAAGACATTAAAGCCTTCTACATGCGCTTAAATGACGACG
GTAAAACTGTTGCAGCAATGGACGTACTTGCTCCAGGTATCGGTGAAATCATCGGTGGTGCACAGCGTGAAGAGCGTTTA
GATGTACTTGATGCACGTCTAGCAGAGATGGAACTTAGTCAGGAAGATTACTGGTGGTACCGCGATCTGCGTCGTTATGG
CACAGTGCCACACGCTGGTTTCGGCCTAGGTTTTGAGCGTTTGGTTTCTTATGTTACTGGTGTATCTAACATCCGTGACG
TGATCCCATTCCCACGCTCACCAAAGTCTGCAAACTTCTAA

Upstream 100 bases:

>100_bases
TACTAAGATACCCTACTTTCCACTTGAGAAAAGTGTTTATACAGGTAATATAAACCTCCAAATTATTTAAAAAAACGTTT
CGTTGGAGAACTAAGCAACA

Downstream 100 bases:

>100_bases
TCGAATAAGCGTTTAGCTACACGATTAAACAATAAAGCCTCTCACATTTATGTCAGAGGCTTTTTTATTAAGCATTCCCC
AATCAAATTCAGTACACAGT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSITSVASVFKGDFAIGSQITVRGWVRSRRDSKAGISFLAVYDGSCFDPIQGVVPNNLENYTNEVLKLTAGCSVVMTGEV
VESPGQGQAFEMQVTKVEVAGLVEDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYNEQGYIWV
STPLITASDTEGAGEMFRVSTLDLENLPRTDKGTVDYAEDFFGKESFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFANLDDAAKLAEDMLKYCFKAVLEERRDDLEFFAQRVEKTAIERLENFVTSDFAQIDYTDAIEIL
KACDKDFEYDVEWGIDLHSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERL
DVLDARLAEMELSQEDYWWYRDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRSPKSANF

Sequences:

>Translated_466_residues
MSITSVASVFKGDFAIGSQITVRGWVRSRRDSKAGISFLAVYDGSCFDPIQGVVPNNLENYTNEVLKLTAGCSVVMTGEV
VESPGQGQAFEMQVTKVEVAGLVEDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYNEQGYIWV
STPLITASDTEGAGEMFRVSTLDLENLPRTDKGTVDYAEDFFGKESFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFANLDDAAKLAEDMLKYCFKAVLEERRDDLEFFAQRVEKTAIERLENFVTSDFAQIDYTDAIEIL
KACDKDFEYDVEWGIDLHSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERL
DVLDARLAEMELSQEDYWWYRDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRSPKSANF
>Mature_465_residues
SITSVASVFKGDFAIGSQITVRGWVRSRRDSKAGISFLAVYDGSCFDPIQGVVPNNLENYTNEVLKLTAGCSVVMTGEVV
ESPGQGQAFEMQVTKVEVAGLVEDPDTYPMAAKRHSIEHLRELAHLRPRTNIIGAVARVRNCLSQAIHRFYNEQGYIWVS
TPLITASDTEGAGEMFRVSTLDLENLPRTDKGTVDYAEDFFGKESFLTVSGQLNAETYACALSKVYTFGPTFRAENSNTS
RHLAEFWMVEPEVAFANLDDAAKLAEDMLKYCFKAVLEERRDDLEFFAQRVEKTAIERLENFVTSDFAQIDYTDAIEILK
ACDKDFEYDVEWGIDLHSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERLD
VLDARLAEMELSQEDYWWYRDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRSPKSANF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=464, Percent_Identity=42.6724137931034, Blast_Score=382, Evalue=1e-106,
Organism=Homo sapiens, GI4758762, Length=451, Percent_Identity=29.0465631929047, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI45439306, Length=342, Percent_Identity=27.7777777777778, Blast_Score=117, Evalue=3e-26,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=78.755364806867, Blast_Score=795, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=338, Percent_Identity=25.1479289940828, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1789256, Length=341, Percent_Identity=25.8064516129032, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71984122, Length=450, Percent_Identity=29.3333333333333, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17556372, Length=433, Percent_Identity=30.2540415704388, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17551876, Length=342, Percent_Identity=27.4853801169591, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319872, Length=471, Percent_Identity=37.3673036093418, Blast_Score=296, Evalue=6e-81,
Organism=Saccharomyces cerevisiae, GI6321807, Length=456, Percent_Identity=30.9210526315789, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6323011, Length=482, Percent_Identity=25.7261410788382, Blast_Score=120, Evalue=4e-28,
Organism=Drosophila melanogaster, GI19922416, Length=464, Percent_Identity=34.4827586206897, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI19921528, Length=473, Percent_Identity=27.4841437632135, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI17136276, Length=343, Percent_Identity=28.5714285714286, Blast_Score=108, Evalue=9e-24,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 52481; Mature: 52349

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITSVASVFKGDFAIGSQITVRGWVRSRRDSKAGISFLAVYDGSCFDPIQGVVPNNLEN
CCHHHHHHHHCCCCCCCCCEEEHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHH
YTNEVLKLTAGCSVVMTGEVVESPGQGQAFEMQVTKVEVAGLVEDPDTYPMAAKRHSIEH
HHHHHHHHHCCCEEEEECHHHCCCCCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHH
LRELAHLRPRTNIIGAVARVRNCLSQAIHRFYNEQGYIWVSTPLITASDTEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCCCEEEEE
TLDLENLPRTDKGTVDYAEDFFGKESFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
EECHHCCCCCCCCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFANLDDAAKLAEDMLKYCFKAVLEERRDDLEFFAQRVEKTAIERL
HHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENFVTSDFAQIDYTDAIEILKACDKDFEYDVEWGIDLHSEHERYLAEEHFKAPVVVKNYP
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERLDVLDARLAEMELSQEDYWWY
HHHHHHEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
RDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRSPKSANF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SITSVASVFKGDFAIGSQITVRGWVRSRRDSKAGISFLAVYDGSCFDPIQGVVPNNLEN
CHHHHHHHHCCCCCCCCCEEEHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHH
YTNEVLKLTAGCSVVMTGEVVESPGQGQAFEMQVTKVEVAGLVEDPDTYPMAAKRHSIEH
HHHHHHHHHCCCEEEEECHHHCCCCCCCEEEEEEEEEEEEEEECCCCCCCCHHHHHHHHH
LRELAHLRPRTNIIGAVARVRNCLSQAIHRFYNEQGYIWVSTPLITASDTEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCCCEEEEE
TLDLENLPRTDKGTVDYAEDFFGKESFLTVSGQLNAETYACALSKVYTFGPTFRAENSNT
EECHHCCCCCCCCCCHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFANLDDAAKLAEDMLKYCFKAVLEERRDDLEFFAQRVEKTAIERL
HHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ENFVTSDFAQIDYTDAIEILKACDKDFEYDVEWGIDLHSEHERYLAEEHFKAPVVVKNYP
HHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERLDVLDARLAEMELSQEDYWWY
HHHHHHEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
RDLRRYGTVPHAGFGLGFERLVSYVTGVSNIRDVIPFPRSPKSANF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA