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The map label for this gene is nudL [H]

Identifier: 157961857

GI number: 157961857

Start: 2463164

End: 2463757

Strand: Reverse

Name: nudL [H]

Synonym: Spea_2036

Alternate gene names: 157961857

Gene position: 2463757-2463164 (Counterclockwise)

Preceding gene: 157961858

Following gene: 157961855

Centisome position: 47.61

GC content: 45.12

Gene sequence:

>594_bases
ATGAAGCTGGCAGAGTTTAGACTCAGGTATAACCTTAATACTTTGCCAGAGCTGGATTTGATTCACTTGAGTCAAAAGCT
GCGTAAAGCTGCCGTGTTAATTGCACTCTATGAAGTCGATAACGAATTAGAGCTAATATTGACTCGCAGACCGACTCATC
TTCGCGCTCATCCGGGTCAAATCAGTTTTCCAGGTGGTAAAGTGGAAGCGTCAGATTCAAGCCATCAATTCACCGCATTA
CGGGAAGCTGAAGAGGAAATTGGCTTGCAGCGCTCAAATGTCGAGGTTATCGGCTCCCTTCCCGCCCACAAAACCTTCAC
GGGTTTTGAGATAACGCCTTTCGTCGGTATCGTGAAGCAAGCTTTTCATCCAGTGTTAGACCCTGGTGAAGTCGATGAAT
ACTTTACTGTGCCACTGTCATATTTACTAAAACAGTATAATCGCCATACACAACGTTTTAGTCGAAAAGGGATTGAGTAT
CCAGTGCACTTTATCCCCTATCAGGAACATTTTATATGGGGCGCAACAGCGGCCATGATTGACTTGCTCTGCAGGCAACT
AAGCTCTAGCTCTGCTTATACAGGCTCTGTTTAA

Upstream 100 bases:

>100_bases
AGGAAAGTTTCGATAAAGTCAGCCGGATCTTGCCTGTGTTGTCACAAATGTAATTTAACCTAGCCTAGAGCTATCCCCTT
TAAAACTAAAAGGATGTTTA

Downstream 100 bases:

>100_bases
CCTAACTCTCTTTTACGGGCTCTGATTAGTCTAGTAAGTTAAACGACGAAGCGGATATACAGCCCCGCCGCTAAGGAGCA
GGTAAACAAGAGTGGGATAT

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKLAEFRLRYNLNTLPELDLIHLSQKLRKAAVLIALYEVDNELELILTRRPTHLRAHPGQISFPGGKVEASDSSHQFTAL
REAEEEIGLQRSNVEVIGSLPAHKTFTGFEITPFVGIVKQAFHPVLDPGEVDEYFTVPLSYLLKQYNRHTQRFSRKGIEY
PVHFIPYQEHFIWGATAAMIDLLCRQLSSSSAYTGSV

Sequences:

>Translated_197_residues
MKLAEFRLRYNLNTLPELDLIHLSQKLRKAAVLIALYEVDNELELILTRRPTHLRAHPGQISFPGGKVEASDSSHQFTAL
REAEEEIGLQRSNVEVIGSLPAHKTFTGFEITPFVGIVKQAFHPVLDPGEVDEYFTVPLSYLLKQYNRHTQRFSRKGIEY
PVHFIPYQEHFIWGATAAMIDLLCRQLSSSSAYTGSV
>Mature_197_residues
MKLAEFRLRYNLNTLPELDLIHLSQKLRKAAVLIALYEVDNELELILTRRPTHLRAHPGQISFPGGKVEASDSSHQFTAL
REAEEEIGLQRSNVEVIGSLPAHKTFTGFEITPFVGIVKQAFHPVLDPGEVDEYFTVPLSYLLKQYNRHTQRFSRKGIEY
PVHFIPYQEHFIWGATAAMIDLLCRQLSSSSAYTGSV

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=139, Percent_Identity=38.1294964028777, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI1788115, Length=161, Percent_Identity=40.3726708074534, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17510677, Length=160, Percent_Identity=35.625, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17536993, Length=167, Percent_Identity=31.1377245508982, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI18859683, Length=159, Percent_Identity=42.7672955974843, Blast_Score=95, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 22394; Mature: 22394

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAEFRLRYNLNTLPELDLIHLSQKLRKAAVLIALYEVDNELELILTRRPTHLRAHPGQ
CCCHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCEEECCCCE
ISFPGGKVEASDSSHQFTALREAEEEIGLQRSNVEVIGSLPAHKTFTGFEITPFVGIVKQ
EECCCCEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCEECCCCHHHHHHHHHH
AFHPVLDPGEVDEYFTVPLSYLLKQYNRHTQRFSRKGIEYPVHFIPYQEHFIWGATAAMI
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHEEHHHHHHHH
DLLCRQLSSSSAYTGSV
HHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKLAEFRLRYNLNTLPELDLIHLSQKLRKAAVLIALYEVDNELELILTRRPTHLRAHPGQ
CCCHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCEEECCCCE
ISFPGGKVEASDSSHQFTALREAEEEIGLQRSNVEVIGSLPAHKTFTGFEITPFVGIVKQ
EECCCCEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCEECCCCHHHHHHHHHH
AFHPVLDPGEVDEYFTVPLSYLLKQYNRHTQRFSRKGIEYPVHFIPYQEHFIWGATAAMI
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHEEHHHHHHHH
DLLCRQLSSSSAYTGSV
HHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA