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The map label for this gene is asd [H]

Identifier: 157961439

GI number: 157961439

Start: 1953056

End: 1954072

Strand: Direct

Name: asd [H]

Synonym: Spea_1613

Alternate gene names: 157961439

Gene position: 1953056-1954072 (Clockwise)

Preceding gene: 157961438

Following gene: 157961442

Centisome position: 37.74

GC content: 44.35

Gene sequence:

>1017_bases
ATGTCGCAGGAATTTAATGTTGTCGTATTAGGTGCATCGGGCGCAGTGGGTCAAACAATGATTGAGATCCTCGAAGAGCG
TAACTTTCCGGTTGCTAATTTATTTCCATTAGCCAGCAGTCGCAGCGCCGGTAATACGGTCAGCTTCCACGGTAAACAGG
TCGAAATTTTAGATGTAGACACCTTTGACTGGTCACAGGCCCAAATCGGTTTCTTCTCTGCAGGTGGTGACGTATCAGCT
AAATGGGCTCCCATTGCTGCTGAAAACGGTTGTGTTGTTATCGATAACACCTCTCACTTCAGATATGACATCGACGTGCC
ATTGGTGATCCCAGAGGTAAACCCTGAAGCGATTGCCGATTTCAGAAACCGTAACATCATTGCTAACCCTAACTGTTCAA
CCATTCAGATGTTGGTTGCGCTTAAGCCTATTTATGATGCATACGGTATTTCGCGTATTAACGTGGCGACTTACCAGTCT
GTATCGGGATCGGGTAAGCAAGCTATTGAAGAGTTAGCAGGCCAGTGCGCTAAGCTTTTACAAGGTTTACCTGTAGAGCC
TAAGACTTATCCTAAGCAAATTGCGTTTAACGTATTGCCACAAATCGATAAGTTTATGGATAACGGCTACACCAAAGAAG
AGATGAAAATGGTGTGGGAAACGCAGAAGATCTTTGGTGATGACAACATCGTTGTGAACCCAACGGCTGTGCGTGTACCA
GTATTTTACGGTCACTCAGAAGCTATTCACCTAGAGACATTACAACCTGCTGATGCCGAAGACATTAAATCCGTATTACG
TGGTGCCGACGGTGTAGAACTATTCGAAGGTGATGAAGATTACCCAACTGCGATAACAGAAGGCGCAGGTACCGATCCTG
TTTATGTTGGTCGTGTGAGAAAAGATATCTCCCATGAGAATGGCATAAACCTTTGGGTTGTATCAGATAACATTCGTAAA
GGCGCAGCACTTAACAGTGTGCAAATCGCTGAAGTTTTGATTAGAGATTATTATTAA

Upstream 100 bases:

>100_bases
CCCATCGCCGCGAATTTAGTGCATTAAAGGTAGGCAACACGGGGCAAACTAATGTAAATTGGTTATCCAATTTAGGGTTT
TCAGGAGTCGAGCTGTAATT

Downstream 100 bases:

>100_bases
TTTCTAGTTCGAACCGACTAAGTGTCCCGTCCTGAAATAGGTTGACGGTTTTTACTAGACCAGTAGCTTCTGCTGCTGGT
CTTTTTTATGCACTTGATTA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSQEFNVVVLGASGAVGQTMIEILEERNFPVANLFPLASSRSAGNTVSFHGKQVEILDVDTFDWSQAQIGFFSAGGDVSA
KWAPIAAENGCVVIDNTSHFRYDIDVPLVIPEVNPEAIADFRNRNIIANPNCSTIQMLVALKPIYDAYGISRINVATYQS
VSGSGKQAIEELAGQCAKLLQGLPVEPKTYPKQIAFNVLPQIDKFMDNGYTKEEMKMVWETQKIFGDDNIVVNPTAVRVP
VFYGHSEAIHLETLQPADAEDIKSVLRGADGVELFEGDEDYPTAITEGAGTDPVYVGRVRKDISHENGINLWVVSDNIRK
GAALNSVQIAEVLIRDYY

Sequences:

>Translated_338_residues
MSQEFNVVVLGASGAVGQTMIEILEERNFPVANLFPLASSRSAGNTVSFHGKQVEILDVDTFDWSQAQIGFFSAGGDVSA
KWAPIAAENGCVVIDNTSHFRYDIDVPLVIPEVNPEAIADFRNRNIIANPNCSTIQMLVALKPIYDAYGISRINVATYQS
VSGSGKQAIEELAGQCAKLLQGLPVEPKTYPKQIAFNVLPQIDKFMDNGYTKEEMKMVWETQKIFGDDNIVVNPTAVRVP
VFYGHSEAIHLETLQPADAEDIKSVLRGADGVELFEGDEDYPTAITEGAGTDPVYVGRVRKDISHENGINLWVVSDNIRK
GAALNSVQIAEVLIRDYY
>Mature_337_residues
SQEFNVVVLGASGAVGQTMIEILEERNFPVANLFPLASSRSAGNTVSFHGKQVEILDVDTFDWSQAQIGFFSAGGDVSAK
WAPIAAENGCVVIDNTSHFRYDIDVPLVIPEVNPEAIADFRNRNIIANPNCSTIQMLVALKPIYDAYGISRINVATYQSV
SGSGKQAIEELAGQCAKLLQGLPVEPKTYPKQIAFNVLPQIDKFMDNGYTKEEMKMVWETQKIFGDDNIVVNPTAVRVPV
FYGHSEAIHLETLQPADAEDIKSVLRGADGVELFEGDEDYPTAITEGAGTDPVYVGRVRKDISHENGINLWVVSDNIRKG
AALNSVQIAEVLIRDYY

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=338, Percent_Identity=42.8994082840237, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1789841, Length=359, Percent_Identity=26.1838440111421, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6320362, Length=383, Percent_Identity=28.7206266318538, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37015; Mature: 36884

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQEFNVVVLGASGAVGQTMIEILEERNFPVANLFPLASSRSAGNTVSFHGKQVEILDVD
CCCCCEEEEEECCCCHHHHHHHHHHHCCCCHHEEEECCCCCCCCCEEEECCCEEEEEEEC
TFDWSQAQIGFFSAGGDVSAKWAPIAAENGCVVIDNTSHFRYDIDVPLVIPEVNPEAIAD
CCCCCCCEEEEEECCCCCCCEEEEEECCCCEEEEECCCCEEEECCCEEEEECCCHHHHHH
FRNRNIIANPNCSTIQMLVALKPIYDAYGISRINVATYQSVSGSGKQAIEELAGQCAKLL
HHCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHH
QGLPVEPKTYPKQIAFNVLPQIDKFMDNGYTKEEMKMVWETQKIFGDDNIVVNPTAVRVP
HCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEECCCEEEEE
VFYGHSEAIHLETLQPADAEDIKSVLRGADGVELFEGDEDYPTAITEGAGTDPVYVGRVR
EEECCCCEEEEEECCCCCHHHHHHHHCCCCCCEEECCCCCCCCEEECCCCCCCEEEHHHH
KDISHENGINLWVVSDNIRKGAALNSVQIAEVLIRDYY
HHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SQEFNVVVLGASGAVGQTMIEILEERNFPVANLFPLASSRSAGNTVSFHGKQVEILDVD
CCCCEEEEEECCCCHHHHHHHHHHHCCCCHHEEEECCCCCCCCCEEEECCCEEEEEEEC
TFDWSQAQIGFFSAGGDVSAKWAPIAAENGCVVIDNTSHFRYDIDVPLVIPEVNPEAIAD
CCCCCCCEEEEEECCCCCCCEEEEEECCCCEEEEECCCCEEEECCCEEEEECCCHHHHHH
FRNRNIIANPNCSTIQMLVALKPIYDAYGISRINVATYQSVSGSGKQAIEELAGQCAKLL
HHCCCEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHH
QGLPVEPKTYPKQIAFNVLPQIDKFMDNGYTKEEMKMVWETQKIFGDDNIVVNPTAVRVP
HCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEECCCEEEEE
VFYGHSEAIHLETLQPADAEDIKSVLRGADGVELFEGDEDYPTAITEGAGTDPVYVGRVR
EEECCCCEEEEEECCCCCHHHHHHHHCCCCCCEEECCCCCCCCEEECCCCCCCEEEHHHH
KDISHENGINLWVVSDNIRKGAALNSVQIAEVLIRDYY
HHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163523 [H]