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The map label for this gene is yggW [H]

Identifier: 157960949

GI number: 157960949

Start: 1360391

End: 1361527

Strand: Reverse

Name: yggW [H]

Synonym: Spea_1121

Alternate gene names: 157960949

Gene position: 1361527-1360391 (Counterclockwise)

Preceding gene: 157960950

Following gene: 157960948

Centisome position: 26.31

GC content: 47.41

Gene sequence:

>1137_bases
ATGTTAACCCTGCCACCGTTAAGCCTATATATCCATATTCCTTGGTGCGTACAAAAGTGCCCTTACTGCGACTTCAATTC
CCATGGACAGCATGGTGAACTGCCGCAAACTGAATATATCGATGCACTGATAAAAGATCTCAAGCAAGATCTGCATTACG
TGCAAGGTAGACGTTTAGACACGATTTTTATCGGTGGCGGCACGCCCTCTCTGTTCGATGCCGCGCAGATTGGGCGCTTA
TTAGCTGAAGTCGATAAGCTAGTTCCGTTTAGCGACAATATCGAAATTACCATGGAGGCTAATCCTGGCACCCTTGAGCA
CGATGATTTCGAAGCTTATTGCAAAGCTGGCGTGACCCGACTATCAATCGGGGTACAGAGTTTCTCTAGCGACAAGCTCA
ACCTGCTCGGGCGTATTCACAATAAAGACGAAGCTCATATTGCCGCCCAAAAGGCTAAAGTCTCTGGTTACCAGAGCTTT
AACTTAGACTTGATGCACGGCCTGCCAAACCAAAGTTTTGATGAAGCCCTTAGCGACATAGAGACCGCAGCAGAGCTTGC
TCCGCCCCACCTGTCTTGGTATCAACTAACGATTGAGCCTAATACCCTATTCCACTCTAAGCCGCCACAGCTTCCTGATG
ATGAAAACCTATGGCAGATCTACGAGCAGGGGCAAAAGCGTCTAGCTGCGCTAGGTTACCAGCAGTACGAGATCTCGGCC
TATGCCAAAGAAGGCTTCCAATGCAGACACAACCTTAACTACTGGCAGTTTGGCGACTACTTAGGGATTGGTTGTGGCGC
TCATGGTAAAATAACCCTACTTGATGACAATAAAATTGTCCGCACCGTCAAGATTAAGCACCCTAAAGGTTATTTAGCCG
CTGATAACTACACCGATGAAACAACAGAGGTGGTAGAGGAAGACAGAGCCTTAGAATATCTGATGAACCGCTTGCGCCTA
ATGAGTCCAATTCCTAAGGTGGAATTTGAACAGCGCACAGGTTTAACTCGAGACACCATCAGTGACGGAGTTAAGCAAGG
CTGTGCTAAGGGCTTAATGACTGAATCGGATGAACACTGGCAGCTGACTAGCAAAGGTCACATGTTCGTCAATGAGCTAC
TGTCACAATTCCTATAG

Upstream 100 bases:

>100_bases
CTGCAGAGCTAAGCAGTGATGAGAAGAATAAGCTAAGCCATCGTGGTAAAGCCCTAGTGTTGTTAATCGAAGCCATGAAG
CAACAAGGTATCTTTAACTA

Downstream 100 bases:

>100_bases
ATGGTATAACGGCTTACTAATACTCCCTAAGCAACTGAATAGCTTAATTAATAAGCCACAGCCTATAGATTTGGAAATAT
TTGCTAACACTTAGATCAAA

Product: putative oxygen-independent coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MLTLPPLSLYIHIPWCVQKCPYCDFNSHGQHGELPQTEYIDALIKDLKQDLHYVQGRRLDTIFIGGGTPSLFDAAQIGRL
LAEVDKLVPFSDNIEITMEANPGTLEHDDFEAYCKAGVTRLSIGVQSFSSDKLNLLGRIHNKDEAHIAAQKAKVSGYQSF
NLDLMHGLPNQSFDEALSDIETAAELAPPHLSWYQLTIEPNTLFHSKPPQLPDDENLWQIYEQGQKRLAALGYQQYEISA
YAKEGFQCRHNLNYWQFGDYLGIGCGAHGKITLLDDNKIVRTVKIKHPKGYLAADNYTDETTEVVEEDRALEYLMNRLRL
MSPIPKVEFEQRTGLTRDTISDGVKQGCAKGLMTESDEHWQLTSKGHMFVNELLSQFL

Sequences:

>Translated_378_residues
MLTLPPLSLYIHIPWCVQKCPYCDFNSHGQHGELPQTEYIDALIKDLKQDLHYVQGRRLDTIFIGGGTPSLFDAAQIGRL
LAEVDKLVPFSDNIEITMEANPGTLEHDDFEAYCKAGVTRLSIGVQSFSSDKLNLLGRIHNKDEAHIAAQKAKVSGYQSF
NLDLMHGLPNQSFDEALSDIETAAELAPPHLSWYQLTIEPNTLFHSKPPQLPDDENLWQIYEQGQKRLAALGYQQYEISA
YAKEGFQCRHNLNYWQFGDYLGIGCGAHGKITLLDDNKIVRTVKIKHPKGYLAADNYTDETTEVVEEDRALEYLMNRLRL
MSPIPKVEFEQRTGLTRDTISDGVKQGCAKGLMTESDEHWQLTSKGHMFVNELLSQFL
>Mature_378_residues
MLTLPPLSLYIHIPWCVQKCPYCDFNSHGQHGELPQTEYIDALIKDLKQDLHYVQGRRLDTIFIGGGTPSLFDAAQIGRL
LAEVDKLVPFSDNIEITMEANPGTLEHDDFEAYCKAGVTRLSIGVQSFSSDKLNLLGRIHNKDEAHIAAQKAKVSGYQSF
NLDLMHGLPNQSFDEALSDIETAAELAPPHLSWYQLTIEPNTLFHSKPPQLPDDENLWQIYEQGQKRLAALGYQQYEISA
YAKEGFQCRHNLNYWQFGDYLGIGCGAHGKITLLDDNKIVRTVKIKHPKGYLAADNYTDETTEVVEEDRALEYLMNRLRL
MSPIPKVEFEQRTGLTRDTISDGVKQGCAKGLMTESDEHWQLTSKGHMFVNELLSQFL

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=298, Percent_Identity=32.5503355704698, Blast_Score=169, Evalue=3e-42,
Organism=Escherichia coli, GI1789325, Length=378, Percent_Identity=57.6719576719577, Blast_Score=461, Evalue=1e-131,
Organism=Escherichia coli, GI87082341, Length=282, Percent_Identity=29.7872340425532, Blast_Score=119, Evalue=4e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 42776; Mature: 42776

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLPPLSLYIHIPWCVQKCPYCDFNSHGQHGELPQTEYIDALIKDLKQDLHYVQGRRLD
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
TIFIGGGTPSLFDAAQIGRLLAEVDKLVPFSDNIEITMEANPGTLEHDDFEAYCKAGVTR
EEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHCCCEE
LSIGVQSFSSDKLNLLGRIHNKDEAHIAAQKAKVSGYQSFNLDLMHGLPNQSFDEALSDI
EEHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEHCCCCCCCCHHHHHHHH
ETAAELAPPHLSWYQLTIEPNTLFHSKPPQLPDDENLWQIYEQGQKRLAALGYQQYEISA
HHHHHHCCCCCCEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHEEHHH
YAKEGFQCRHNLNYWQFGDYLGIGCGAHGKITLLDDNKIVRTVKIKHPKGYLAADNYTDE
HHHCCHHHHCCCCCEECCCEEEECCCCCCEEEEEECCCEEEEEEEECCCCCEECCCCCCH
TTEVVEEDRALEYLMNRLRLMSPIPKVEFEQRTGLTRDTISDGVKQGCAKGLMTESDEHW
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCE
QLTSKGHMFVNELLSQFL
EECCCCHHHHHHHHHHHC
>Mature Secondary Structure
MLTLPPLSLYIHIPWCVQKCPYCDFNSHGQHGELPQTEYIDALIKDLKQDLHYVQGRRLD
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
TIFIGGGTPSLFDAAQIGRLLAEVDKLVPFSDNIEITMEANPGTLEHDDFEAYCKAGVTR
EEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHCCCEE
LSIGVQSFSSDKLNLLGRIHNKDEAHIAAQKAKVSGYQSFNLDLMHGLPNQSFDEALSDI
EEHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEHCCCCCCCCHHHHHHHH
ETAAELAPPHLSWYQLTIEPNTLFHSKPPQLPDDENLWQIYEQGQKRLAALGYQQYEISA
HHHHHHCCCCCCEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHEEHHH
YAKEGFQCRHNLNYWQFGDYLGIGCGAHGKITLLDDNKIVRTVKIKHPKGYLAADNYTDE
HHHCCHHHHCCCCCEECCCEEEECCCCCCEEEEEECCCEEEEEEEECCCCCEECCCCCCH
TTEVVEEDRALEYLMNRLRLMSPIPKVEFEQRTGLTRDTISDGVKQGCAKGLMTESDEHW
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCE
QLTSKGHMFVNELLSQFL
EECCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]