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The map label for this gene is yggV [C]

Identifier: 157960950

GI number: 157960950

Start: 1361527

End: 1362126

Strand: Reverse

Name: yggV [C]

Synonym: Spea_1122

Alternate gene names: 157960950

Gene position: 1362126-1361527 (Counterclockwise)

Preceding gene: 157960951

Following gene: 157960949

Centisome position: 26.32

GC content: 47.33

Gene sequence:

>600_bases
ATGAATCAAATCGTCCTTGCTAGCGGCAACAAAGGTAAACTCAAAGAATTTTCTGAATTGATGGCCGATTACGGCGTCGA
GATCTTAGCTCAGAGCCAATTCAATGTGTCAGAAGTGGCTGAGACGGGTACCACATTTGTTGAAAATGCCATCATCAAGG
CCAGACATGCCGCTGAGATCACTGGCCATGCCGCCATTGCCGATGACTCGGGTCTAGAAGTTGACTTCTTACAAGGCGCA
CCCGGTATTTACTCGGCGCGTTACGCTGGAGAAGGCGCTAAAGATGAGCAAAACTACACAAAATTATTAAATGCCCTTGA
AGACCAAGCTGAGCGTAGTGCACGCTTTCAGTGCGTATTGGTTTATATGCGTCATGCTAAAGATCCAACCCCAATCATCT
GCCAAGCGTCATGGGAAGGCACTATTGGTTTTGCTGCGCAAGGCGTAAACGGCCACGGTTACGATCCTATCTTTATCCCT
GCAGAGCACGAATGCGCTGCTGCAGAGCTAAGCAGTGATGAGAAGAATAAGCTAAGCCATCGTGGTAAAGCCCTAGTGTT
GTTAATCGAAGCCATGAAGCAACAAGGTATCTTTAACTAA

Upstream 100 bases:

>100_bases
GCCTAGCGCCCCTGTTTTTTTGTGACGTTTACTCTATCGAAAACCCCGTATCTCGGCTATTATTGCCGCCATTATTTTTA
GACTCATCTACAGGCATCCC

Downstream 100 bases:

>100_bases
TGTTAACCCTGCCACCGTTAAGCCTATATATCCATATTCCTTGGTGCGTACAAAAGTGCCCTTACTGCGACTTCAATTCC
CATGGACAGCATGGTGAACT

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MNQIVLASGNKGKLKEFSELMADYGVEILAQSQFNVSEVAETGTTFVENAIIKARHAAEITGHAAIADDSGLEVDFLQGA
PGIYSARYAGEGAKDEQNYTKLLNALEDQAERSARFQCVLVYMRHAKDPTPIICQASWEGTIGFAAQGVNGHGYDPIFIP
AEHECAAAELSSDEKNKLSHRGKALVLLIEAMKQQGIFN

Sequences:

>Translated_199_residues
MNQIVLASGNKGKLKEFSELMADYGVEILAQSQFNVSEVAETGTTFVENAIIKARHAAEITGHAAIADDSGLEVDFLQGA
PGIYSARYAGEGAKDEQNYTKLLNALEDQAERSARFQCVLVYMRHAKDPTPIICQASWEGTIGFAAQGVNGHGYDPIFIP
AEHECAAAELSSDEKNKLSHRGKALVLLIEAMKQQGIFN
>Mature_199_residues
MNQIVLASGNKGKLKEFSELMADYGVEILAQSQFNVSEVAETGTTFVENAIIKARHAAEITGHAAIADDSGLEVDFLQGA
PGIYSARYAGEGAKDEQNYTKLLNALEDQAERSARFQCVLVYMRHAKDPTPIICQASWEGTIGFAAQGVNGHGYDPIFIP
AEHECAAAELSSDEKNKLSHRGKALVLLIEAMKQQGIFN

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=196, Percent_Identity=55.1020408163265, Blast_Score=230, Evalue=5e-62,
Organism=Drosophila melanogaster, GI19920712, Length=192, Percent_Identity=28.6458333333333, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21545; Mature: 21545

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQIVLASGNKGKLKEFSELMADYGVEILAQSQFNVSEVAETGTTFVENAIIKARHAAEI
CCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHCHHHHHHHHHHHHHHHHH
TGHAAIADDSGLEVDFLQGAPGIYSARYAGEGAKDEQNYTKLLNALEDQAERSARFQCVL
CCCEEECCCCCCEEEEECCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHE
VYMRHAKDPTPIICQASWEGTIGFAAQGVNGHGYDPIFIPAEHECAAAELSSDEKNKLSH
EEHHHCCCCCCEEEECCCCCCEEEEEECCCCCCCCCEEECCCCCHHHHHCCCCHHHHHHH
RGKALVLLIEAMKQQGIFN
CCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNQIVLASGNKGKLKEFSELMADYGVEILAQSQFNVSEVAETGTTFVENAIIKARHAAEI
CCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCCCHHHHHHHCHHHHHHHHHHHHHHHHH
TGHAAIADDSGLEVDFLQGAPGIYSARYAGEGAKDEQNYTKLLNALEDQAERSARFQCVL
CCCEEECCCCCCEEEEECCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHE
VYMRHAKDPTPIICQASWEGTIGFAAQGVNGHGYDPIFIPAEHECAAAELSSDEKNKLSH
EEHHHCCCCCCEEEECCCCCCEEEEEECCCCCCCCCEEECCCCCHHHHHCCCCHHHHHHH
RGKALVLLIEAMKQQGIFN
CCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]