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The map label for this gene is slyD [H]

Identifier: 157960893

GI number: 157960893

Start: 1287793

End: 1288452

Strand: Reverse

Name: slyD [H]

Synonym: Spea_1065

Alternate gene names: 157960893

Gene position: 1288452-1287793 (Counterclockwise)

Preceding gene: 157960898

Following gene: 157960892

Centisome position: 24.9

GC content: 49.55

Gene sequence:

>660_bases
ATGAAAATCACCGAAAAATGTGCTGTTAGCATCCATTACCGATTATCAGATGCGAAAGGTCAGCTTGTAGAAAGTTCTTT
TGAAGGCGAGCCAATGATCTATCTGCATGGTGCAGAAAACATGATCCCTGGTTTAGAAGCTGCGCTTGAAGGCAAAGCAC
AAGGTGACATCCTTGATGTAACTGTTGATGCAGAGCAAGGCTACGGCCCATATCATGATGGTCTTCGCCAAGAAGTGCCA
ATCTCTGCATTTGGCGATATCGAAGATATCGTTCCAGGCATGCGCTTTATTGCAGAAACTGAAATGGGCCAGCGCCCAGT
TCAAGTTACTGAGGTTAAAGATGATGTTGTCGTTGTTGACGGTAACCACCCTCTTGCAGGCCAATCTCTAGCCTTCAACG
TTGAAGTACTTGAAGTACGCGCAGCAACTGAAGAAGAGATCGCTCACGGTCATATCCACGCTCATGGCGGCGGATGTGGT
AGCCATGGCCACTCTCATGAAGGCGGCTGTTGTGGCGGCGGACACGATCACGGACAAGAAGGCGGTTGCTGTGGTGGTGA
ACACGATCACGGACACGAAGGCGGTTGCTGTAGTGACGATGAAACAAAAGAAGCTAAAGAAGGCTGTGACGGTAACGGCG
GCTGTGGCTGCAGACACTAA

Upstream 100 bases:

>100_bases
GAAATTAAAGATGTGGCTTAGGTAGCAGAAGTACATTCACTCTATCGCAAATCCCTTTAAAGCAGGCTAGAATGCGCGCA
AATTTCCGATTGGAGCCAAT

Downstream 100 bases:

>100_bases
ATTCTGCTAGTTCTTTAGAATGAATTTAAGCCCGTTTCACCGATTAATGTGAAGCGGGCTTTTTTTTGGTCTACACTGCA
GCCGTTAGCTATCAATGCTA

Product: FKBP-type peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MKITEKCAVSIHYRLSDAKGQLVESSFEGEPMIYLHGAENMIPGLEAALEGKAQGDILDVTVDAEQGYGPYHDGLRQEVP
ISAFGDIEDIVPGMRFIAETEMGQRPVQVTEVKDDVVVVDGNHPLAGQSLAFNVEVLEVRAATEEEIAHGHIHAHGGGCG
SHGHSHEGGCCGGGHDHGQEGGCCGGEHDHGHEGGCCSDDETKEAKEGCDGNGGCGCRH

Sequences:

>Translated_219_residues
MKITEKCAVSIHYRLSDAKGQLVESSFEGEPMIYLHGAENMIPGLEAALEGKAQGDILDVTVDAEQGYGPYHDGLRQEVP
ISAFGDIEDIVPGMRFIAETEMGQRPVQVTEVKDDVVVVDGNHPLAGQSLAFNVEVLEVRAATEEEIAHGHIHAHGGGCG
SHGHSHEGGCCGGGHDHGQEGGCCGGEHDHGHEGGCCSDDETKEAKEGCDGNGGCGCRH
>Mature_219_residues
MKITEKCAVSIHYRLSDAKGQLVESSFEGEPMIYLHGAENMIPGLEAALEGKAQGDILDVTVDAEQGYGPYHDGLRQEVP
ISAFGDIEDIVPGMRFIAETEMGQRPVQVTEVKDDVVVVDGNHPLAGQSLAFNVEVLEVRAATEEEIAHGHIHAHGGGCG
SHGHSHEGGCCGGGHDHGQEGGCCGGEHDHGHEGGCCSDDETKEAKEGCDGNGGCGCRH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=148, Percent_Identity=50, Blast_Score=138, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 22989; Mature: 22989

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITEKCAVSIHYRLSDAKGQLVESSFEGEPMIYLHGAENMIPGLEAALEGKAQGDILDV
CCCCCCEEEEEEEEECCCCCHHHHCCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCEEEE
TVDAEQGYGPYHDGLRQEVPISAFGDIEDIVPGMRFIAETEMGQRPVQVTEVKDDVVVVD
EEECCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEE
GNHPLAGQSLAFNVEVLEVRAATEEEIAHGHIHAHGGGCGSHGHSHEGGCCGGGHDHGQE
CCCCCCCCEEEEEEEEEEEECCCHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
GGCCGGEHDHGHEGGCCSDDETKEAKEGCDGNGGCGCRH
CCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MKITEKCAVSIHYRLSDAKGQLVESSFEGEPMIYLHGAENMIPGLEAALEGKAQGDILDV
CCCCCCEEEEEEEEECCCCCHHHHCCCCCCCEEEEECCCCCCCCHHHHHCCCCCCCEEEE
TVDAEQGYGPYHDGLRQEVPISAFGDIEDIVPGMRFIAETEMGQRPVQVTEVKDDVVVVD
EEECCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEE
GNHPLAGQSLAFNVEVLEVRAATEEEIAHGHIHAHGGGCGSHGHSHEGGCCGGGHDHGQE
CCCCCCCCEEEEEEEEEEEECCCHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
GGCCGGEHDHGHEGGCCSDDETKEAKEGCDGNGGCGCRH
CCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]