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The map label for this gene is rpe [H]

Identifier: 157960073

GI number: 157960073

Start: 274371

End: 275045

Strand: Direct

Name: rpe [H]

Synonym: Spea_0244

Alternate gene names: 157960073

Gene position: 274371-275045 (Clockwise)

Preceding gene: 157960070

Following gene: 157960074

Centisome position: 5.3

GC content: 46.67

Gene sequence:

>675_bases
ATGCGTCCATTTTTGATTGCTCCTTCTATTTTATCTGCCGATTTTGCTCGTTTAGGTGAAGATGTCGATGCGGTATTAGC
CGCAGGGGCAGATGTAGTTCATTTTGATGTCATGGACAATCATTATGTGCCAAATCTAACAATTGGCCCTATGGTATGCC
AGGCGCTACGCAACTACGGTGTCACAGCCGATATCGACGTGCACCTAATGGTGAAGCCAGTCGACCGCATCATTCCTGAT
TTTGCTGAGGCGGGTGCATCGATTATTACGTTCCATCCAGAAGCCTCTGAGCATGTGGACCGCACGCTGCAGCTGATTAA
AGAGTCTGGCTGTAAAGCGGGCCTAGTATTTAACCCAGCAACGCCTCTTCATTACCTAGACCATGTAATGGATAAACTAG
ACGTGATTTTGCTTATGTCAGTAAACCCAGGTTTTGGTGGCCAATCATTTATTCCGACTACTTTGGATAAATTGCGTCAA
GTGCGTAAGTTGATTGATGACAGCGGTTACGACATTCGCTTACAAGTTGATGGCGGTGTAAAGGTCGATAATATTGGCGA
AATCGCAGCTGCGGGGGCGGACATGTTTGTTGCAGGTTCAGCTATTTTCAATAAGCCTGATTACAAGGCGGTAATCGACG
AGATGCGTGCAGAACTTGCAAGCGTTGAGGCGTAA

Upstream 100 bases:

>100_bases
TTTATCTATGCAATTTATCTTAAATGGGCGCTCAAGTCTGGAGGGCTATAGCTGCAACAGGTAGAATAGCGTATTTCTTA
AACATTCAGGTGAGTTCGAT

Downstream 100 bases:

>100_bases
TCAATGAACCCTTTTAGTCAAATCAACGCGGTAGCATTTGACTTAGACGGAACGCTGATCGATAGCGTTCCGGATCTAGC
GGCTGCCACGCGCGCGACCC

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MRPFLIAPSILSADFARLGEDVDAVLAAGADVVHFDVMDNHYVPNLTIGPMVCQALRNYGVTADIDVHLMVKPVDRIIPD
FAEAGASIITFHPEASEHVDRTLQLIKESGCKAGLVFNPATPLHYLDHVMDKLDVILLMSVNPGFGGQSFIPTTLDKLRQ
VRKLIDDSGYDIRLQVDGGVKVDNIGEIAAAGADMFVAGSAIFNKPDYKAVIDEMRAELASVEA

Sequences:

>Translated_224_residues
MRPFLIAPSILSADFARLGEDVDAVLAAGADVVHFDVMDNHYVPNLTIGPMVCQALRNYGVTADIDVHLMVKPVDRIIPD
FAEAGASIITFHPEASEHVDRTLQLIKESGCKAGLVFNPATPLHYLDHVMDKLDVILLMSVNPGFGGQSFIPTTLDKLRQ
VRKLIDDSGYDIRLQVDGGVKVDNIGEIAAAGADMFVAGSAIFNKPDYKAVIDEMRAELASVEA
>Mature_224_residues
MRPFLIAPSILSADFARLGEDVDAVLAAGADVVHFDVMDNHYVPNLTIGPMVCQALRNYGVTADIDVHLMVKPVDRIIPD
FAEAGASIITFHPEASEHVDRTLQLIKESGCKAGLVFNPATPLHYLDHVMDKLDVILLMSVNPGFGGQSFIPTTLDKLRQ
VRKLIDDSGYDIRLQVDGGVKVDNIGEIAAAGADMFVAGSAIFNKPDYKAVIDEMRAELASVEA

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=212, Percent_Identity=40.0943396226415, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI219879828, Length=212, Percent_Identity=38.6792452830189, Blast_Score=147, Evalue=9e-36,
Organism=Homo sapiens, GI24307923, Length=168, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=3e-20,
Organism=Escherichia coli, GI1789788, Length=222, Percent_Identity=86.4864864864865, Blast_Score=397, Evalue=1e-112,
Organism=Escherichia coli, GI1790523, Length=201, Percent_Identity=36.81592039801, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1790754, Length=211, Percent_Identity=29.8578199052133, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17552948, Length=221, Percent_Identity=41.6289592760181, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6322341, Length=229, Percent_Identity=37.9912663755458, Blast_Score=152, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24586301, Length=211, Percent_Identity=39.8104265402844, Blast_Score=155, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24230; Mature: 24230

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPFLIAPSILSADFARLGEDVDAVLAAGADVVHFDVMDNHYVPNLTIGPMVCQALRNYG
CCCCEECCHHHHHHHHHHCCHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
VTADIDVHLMVKPVDRIIPDFAEAGASIITFHPEASEHVDRTLQLIKESGCKAGLVFNPA
CEECEEEEEEECCHHHHCHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCC
TPLHYLDHVMDKLDVILLMSVNPGFGGQSFIPTTLDKLRQVRKLIDDSGYDIRLQVDGGV
CHHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCE
KVDNIGEIAAAGADMFVAGSAIFNKPDYKAVIDEMRAELASVEA
EECCCCHHHHCCCCCEEECHHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRPFLIAPSILSADFARLGEDVDAVLAAGADVVHFDVMDNHYVPNLTIGPMVCQALRNYG
CCCCEECCHHHHHHHHHHCCHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
VTADIDVHLMVKPVDRIIPDFAEAGASIITFHPEASEHVDRTLQLIKESGCKAGLVFNPA
CEECEEEEEEECCHHHHCHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCC
TPLHYLDHVMDKLDVILLMSVNPGFGGQSFIPTTLDKLRQVRKLIDDSGYDIRLQVDGGV
CHHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCE
KVDNIGEIAAAGADMFVAGSAIFNKPDYKAVIDEMRAELASVEA
EECCCCHHHHCCCCCEEECHHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]