Click here to switch to the map view.

The map label for this gene is aroK [H]

Identifier: 157960067

GI number: 157960067

Start: 269451

End: 269966

Strand: Direct

Name: aroK [H]

Synonym: Spea_0238

Alternate gene names: 157960067

Gene position: 269451-269966 (Clockwise)

Preceding gene: 157960066

Following gene: 157960068

Centisome position: 5.21

GC content: 45.16

Gene sequence:

>516_bases
ATGGCCGAGAAACGTAATATTTTCCTAGTAGGCCCTATGGGGGCTGGTAAAAGCACTATAGGCCGTCATCTGGCACAGAT
GCTGCACTTAGAGTTCCACGATTCAGATCAAGAAATTGAAAGCCGCACAGGAGCTGATATCGCTTGGGTTTTTGATGTTG
AAGGTGAAGAGGGTTTCCGCATTCGTGAAACACAAGTTGTCGCTGATCTGACAGAAAAACAAGGTATTGTCCTAGCAACA
GGCGGTGGTTCGATTCAAAGCAAAGAGATCCGTAATAATCTTTCTGCACGCGGCATCGTTGTTTACCTAGAAACTACTAT
CGATAAGCAAGTCGCGCGTACGCAAAGAGATAAGCGTCGTCCATTGCTACAGGTTGACGACCCAAGAGAAGTGCTAGAGA
GTCTAGCCGAGGTACGCAATCCTCTTTACGAAGAGATTGCAGACGTCATCGTTAAGACTGACGAACAAAGTGCCAAAGTT
GTTGCAAATCAAATTATCGAACAGTTAGGTTTTTAA

Upstream 100 bases:

>100_bases
TGCGGTCAAGTCTCAATAGAGCAAGGTAAGATTAAAGGTCAACTCCGTTAATTTGAGTTGACGTTGGCAAACTTAAATAA
GATTCAGACGTATAAATCAA

Downstream 100 bases:

>100_bases
GATATGGCTAAACAGGTTCTGGTTGAGCTCGGAGAGCGTAGTTACCCAATTGAAATTGGCCAGAATTTGTTTAGTAGTAG
CGAGCCATTGGCTCGCTATC

Product: shikimate kinase I

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MAEKRNIFLVGPMGAGKSTIGRHLAQMLHLEFHDSDQEIESRTGADIAWVFDVEGEEGFRIRETQVVADLTEKQGIVLAT
GGGSIQSKEIRNNLSARGIVVYLETTIDKQVARTQRDKRRPLLQVDDPREVLESLAEVRNPLYEEIADVIVKTDEQSAKV
VANQIIEQLGF

Sequences:

>Translated_171_residues
MAEKRNIFLVGPMGAGKSTIGRHLAQMLHLEFHDSDQEIESRTGADIAWVFDVEGEEGFRIRETQVVADLTEKQGIVLAT
GGGSIQSKEIRNNLSARGIVVYLETTIDKQVARTQRDKRRPLLQVDDPREVLESLAEVRNPLYEEIADVIVKTDEQSAKV
VANQIIEQLGF
>Mature_170_residues
AEKRNIFLVGPMGAGKSTIGRHLAQMLHLEFHDSDQEIESRTGADIAWVFDVEGEEGFRIRETQVVADLTEKQGIVLATG
GGSIQSKEIRNNLSARGIVVYLETTIDKQVARTQRDKRRPLLQVDDPREVLESLAEVRNPLYEEIADVIVKTDEQSAKVV
ANQIIEQLGF

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=170, Percent_Identity=78.2352941176471, Blast_Score=274, Evalue=2e-75,
Organism=Escherichia coli, GI1786587, Length=159, Percent_Identity=34.5911949685535, Blast_Score=90, Evalue=9e-20,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 19113; Mature: 18982

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKRNIFLVGPMGAGKSTIGRHLAQMLHLEFHDSDQEIESRTGADIAWVFDVEGEEGFR
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCCCE
IRETQVVADLTEKQGIVLATGGGSIQSKEIRNNLSARGIVVYLETTIDKQVARTQRDKRR
EEHHHHHHHHHHCCCEEEEECCCCCCHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHCC
PLLQVDDPREVLESLAEVRNPLYEEIADVIVKTDEQSAKVVANQIIEQLGF
CCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEKRNIFLVGPMGAGKSTIGRHLAQMLHLEFHDSDQEIESRTGADIAWVFDVEGEEGFR
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEEECCCCCCE
IRETQVVADLTEKQGIVLATGGGSIQSKEIRNNLSARGIVVYLETTIDKQVARTQRDKRR
EEHHHHHHHHHHCCCEEEEECCCCCCHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHCC
PLLQVDDPREVLESLAEVRNPLYEEIADVIVKTDEQSAKVVANQIIEQLGF
CCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA