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The map label for this gene is aroB [H]

Identifier: 157960068

GI number: 157960068

Start: 269970

End: 271049

Strand: Direct

Name: aroB [H]

Synonym: Spea_0239

Alternate gene names: 157960068

Gene position: 269970-271049 (Clockwise)

Preceding gene: 157960067

Following gene: 157960069

Centisome position: 5.22

GC content: 45.46

Gene sequence:

>1080_bases
ATGGCTAAACAGGTTCTGGTTGAGCTCGGAGAGCGTAGTTACCCAATTGAAATTGGCCAGAATTTGTTTAGTAGTAGCGA
GCCATTGGCTCGCTATCTTCAAAATAAAAACATACTAATCGTCACCAACGAAACGATAGCGCCTCTCTATCTTCAACAGA
TAGAAGCTATGCTGTCGGATTTCGCGTGCGTCAAACCCGTCATTCTTCCCGACGGTGAACAGTACAAAACGCTTGAACAG
ATGAATACGATATTCACTTCATTGCTAGAACAGAATCTAGGTAGAGATACGGTTTTGATTGCTCTAGGCGGTGGTGTGAT
TGGCGATATGACAGGTTTTGCTGCAGCGAGCTACCAGCGTGGTGTGGATTTTATTCAGATCCCCACGACCTTGTTGTCTC
AAGTGGATTCCTCTGTTGGTGGTAAAACCGCAGTTAATCATCCACTAGGTAAAAATATGATAGGCGCCTTCTATCAACCT
AAGTGTGTATTAATTGACACCCATTGCCTAAGCACTTTACCTAAGCGCGAGTTTGCTGCGGGAATGGCTGAGGTGATCAA
GTACGGTGTTATTTGGGATGCCGAGTTTTTCCAATGGCTTGAAAACAACGTTGAAGCGTTGAAATCATTAGATACACAAG
CGCTCGAATATGCAATTAGCCGTTGCTGTGAAATTAAGGCCGAAGTCGTAGAGAAGGACGAAACCGAACAAGCTGTGCGT
GCATTGCTTAATTTGGGACATACCTTTGGCCACGCAATAGAAGCTGAAATGGGCTACGGTGTTTGGCTGCACGGTGAAGC
TGTCTCTGCTGGCACAGTCCTTGCTGCAATAACCTCAAATAAGCTTGGGTTAGTTGATGAGTCAATTGTTTGTCGTATAA
CAGCGTTATTAGCGGCATTTGATCTGCCTACAACTGCTCCCGACACAATGGATTTTGAGCAATTCATTAAGCATATGCGC
CGCGACAAGAAGGTGCTCAAAGGTCAGTTACGACTCATTTTACCTGAAGGCATAGGCCAAGCAGGGATCTACAGTGACGT
TACCGATGAGCTGCTGGAAGAGGTTATCAGCTGCGCATAA

Upstream 100 bases:

>100_bases
TCCTCTTTACGAAGAGATTGCAGACGTCATCGTTAAGACTGACGAACAAAGTGCCAAAGTTGTTGCAAATCAAATTATCG
AACAGTTAGGTTTTTAAGAT

Downstream 100 bases:

>100_bases
ACTATGTGGCAGGTGATGGGTGAACGCTAAATTCAGTATTCAAAAACAAGTCTTTAAATTTTCTTTCCTAGCTATGAGCC
CTTTTAGACATAGTTACGGA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MAKQVLVELGERSYPIEIGQNLFSSSEPLARYLQNKNILIVTNETIAPLYLQQIEAMLSDFACVKPVILPDGEQYKTLEQ
MNTIFTSLLEQNLGRDTVLIALGGGVIGDMTGFAAASYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
KCVLIDTHCLSTLPKREFAAGMAEVIKYGVIWDAEFFQWLENNVEALKSLDTQALEYAISRCCEIKAEVVEKDETEQAVR
ALLNLGHTFGHAIEAEMGYGVWLHGEAVSAGTVLAAITSNKLGLVDESIVCRITALLAAFDLPTTAPDTMDFEQFIKHMR
RDKKVLKGQLRLILPEGIGQAGIYSDVTDELLEEVISCA

Sequences:

>Translated_359_residues
MAKQVLVELGERSYPIEIGQNLFSSSEPLARYLQNKNILIVTNETIAPLYLQQIEAMLSDFACVKPVILPDGEQYKTLEQ
MNTIFTSLLEQNLGRDTVLIALGGGVIGDMTGFAAASYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
KCVLIDTHCLSTLPKREFAAGMAEVIKYGVIWDAEFFQWLENNVEALKSLDTQALEYAISRCCEIKAEVVEKDETEQAVR
ALLNLGHTFGHAIEAEMGYGVWLHGEAVSAGTVLAAITSNKLGLVDESIVCRITALLAAFDLPTTAPDTMDFEQFIKHMR
RDKKVLKGQLRLILPEGIGQAGIYSDVTDELLEEVISCA
>Mature_358_residues
AKQVLVELGERSYPIEIGQNLFSSSEPLARYLQNKNILIVTNETIAPLYLQQIEAMLSDFACVKPVILPDGEQYKTLEQM
NTIFTSLLEQNLGRDTVLIALGGGVIGDMTGFAAASYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPK
CVLIDTHCLSTLPKREFAAGMAEVIKYGVIWDAEFFQWLENNVEALKSLDTQALEYAISRCCEIKAEVVEKDETEQAVRA
LLNLGHTFGHAIEAEMGYGVWLHGEAVSAGTVLAAITSNKLGLVDESIVCRITALLAAFDLPTTAPDTMDFEQFIKHMRR
DKKVLKGQLRLILPEGIGQAGIYSDVTDELLEEVISCA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=356, Percent_Identity=59.5505617977528, Blast_Score=422, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6320332, Length=390, Percent_Identity=36.9230769230769, Blast_Score=216, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39350; Mature: 39219

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQVLVELGERSYPIEIGQNLFSSSEPLARYLQNKNILIVTNETIAPLYLQQIEAMLSD
CCHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHH
FACVKPVILPDGEQYKTLEQMNTIFTSLLEQNLGRDTVLIALGGGVIGDMTGFAAASYQR
HHHHCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHH
GVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPKCVLIDTHCLSTLPKREFAA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEEHHHHHHCCHHHHHH
GMAEVIKYGVIWDAEFFQWLENNVEALKSLDTQALEYAISRCCEIKAEVVEKDETEQAVR
HHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALLNLGHTFGHAIEAEMGYGVWLHGEAVSAGTVLAAITSNKLGLVDESIVCRITALLAAF
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
DLPTTAPDTMDFEQFIKHMRRDKKVLKGQLRLILPEGIGQAGIYSDVTDELLEEVISCA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKQVLVELGERSYPIEIGQNLFSSSEPLARYLQNKNILIVTNETIAPLYLQQIEAMLSD
CHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHH
FACVKPVILPDGEQYKTLEQMNTIFTSLLEQNLGRDTVLIALGGGVIGDMTGFAAASYQR
HHHHCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHH
GVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPKCVLIDTHCLSTLPKREFAA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEEHHHHHHCCHHHHHH
GMAEVIKYGVIWDAEFFQWLENNVEALKSLDTQALEYAISRCCEIKAEVVEKDETEQAVR
HHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALLNLGHTFGHAIEAEMGYGVWLHGEAVSAGTVLAAITSNKLGLVDESIVCRITALLAAF
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHH
DLPTTAPDTMDFEQFIKHMRRDKKVLKGQLRLILPEGIGQAGIYSDVTDELLEEVISCA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA