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The map label for this gene is pilQ [H]

Identifier: 157960066

GI number: 157960066

Start: 267170

End: 269236

Strand: Direct

Name: pilQ [H]

Synonym: Spea_0237

Alternate gene names: 157960066

Gene position: 267170-269236 (Clockwise)

Preceding gene: 157960065

Following gene: 157960067

Centisome position: 5.16

GC content: 42.53

Gene sequence:

>2067_bases
ATGACTGAGGGAATAATGAGATCTTTAACCACGCCAAAAGCCAGCTTTAAGGTAATGCCTTTAGTTAAGGTCATTATTGG
TTTCGTATTAATCGTTGGCATGACTCAGCATTCATATGCCGCAAATCGACTCATTGATGTCAAATATCACGCCGTTGTGG
ATCATCAGCTAGAACTACAGTTGATTTTTGAGAACGATATTAAAGAGCCTGAAATCGATTTAAATGCCTCTCCTGCACAG
ATCATTCTAGGGTTTGACGACAGTATTTCAGCATTAGAAAAGCAAACTTTGCCGATTAAAACCGTTGGTGTAGAAACTGT
GAGTACGGTACCCAATGGTAATAACTTACAGGTTTTTGTAGGCTTAAATAAGGTGAAGCCTTATCAAGGTAAAGTGGTGG
GTAATACCTATCGTTTAACCATTAATGACGAGGTGGCCAGTCAGGGAATAGCAGGCGAAAATCCTTTTGTTAATAGCATT
GAGAATATTGATTTCCGCCGTACAGCTGATGGTGGTGGCGAGCTACTTGTAAAGCTCAATAATAGCTCCGTGGCTGCTAA
CGTTGAGCAGGTCGGTGCCAAGCTCGAACTAAAACTTTATAACACAGATATTAATAGTGATTTCTTATACGTGATGGATG
TATATGATTTTGCGACACCCGTTAAGAGTTTTGAGACATTCAAAGAAGATTTAACCGCACGCTTTCTTATCGATATTGAC
GGTAACTATGAATATAACTACAAGCAAGACGGTAGTTTGTTCAAGTTAACCATGAAGAAAACCGAGCGCATGAATATCGT
TAAGGAAGATAAGAAATATGATGGACGTTCACTGTCATTAAACTTCCAGAATATTTCGGTTAGAACCGTGCTGCAGATTA
TTGCCGATTACAACAACTTCAACTTGGTCACCAGTGATACAGTTGAAGGGGATATCACTTTAAGACTAGATGATGTGCCT
TGGGATCAGGCATTAGATCTTATTCTGCAAGCAAAAGGCTTAGATAAGCGTATTGAAGGTAATATCTTGATGGTTGCACC
TATCGAGGAGATCGCTATCCGTGAAAGCCAAGAGCTAAAGAATATGCAGGAAGTAAAGGAGCTAGCTCCGCTTTACTCTG
AATATTTACAGATTAACTATGCTAAAGCCGTCGATATTGCCGCCTTGCTAAAGGGCGAAGACTCTAGTCTGTTAACTAGC
CGTGGTAGTGTCGCAGTAGATGAGCGTACCAATACCCTATTGGTCAAAGATACTGAAGAGACATTGGAAAACATTCACCG
CCTAATTGAAGTCTTAGATATACCAATCAAGCAGGTGTTGATTGAAGCGCGTATGGTGACAGTAAAGGACGATGTTTCAG
AAGATCTTGGTGTGCGTTGGGGTGTTACTGATCAACAAGGAGATAAAGGAACGTCAGGTAGTTTAGAGGGGGCGGGTGAT
ATCGCAAACGGCATAGTACCAAGCTTAAGCGATCGTTTAAACGTTAACCTTCCCGCAGCTGTGGCTAATCCTACAAGCAT
TGCATTTCATGTGGCTAAGCTTGCTGATGGTACAGTGCTAGACCTTGAGCTGAGTGCCTTAGAACAAGAAAATAAGGGTG
AGATTATTGCGAGTCCGCGTATCACTACTTCTAACCAGAAAGCCGCTTTCATCGAGCAAGGTGTTGAGATCCCCTATGTT
GAGGCAAGCTCAAGTGGTGCAACAACGGTAACCTTTAAAAAGGCAGTGTTATCGCTACGAGTGACACCTCAAATCACACC
CGATAACCGAGTAATTTTAGATCTTGAAATTACCCAAGACTCGCAAGGTAAGACGGTTGATACGCCAACAGGACAAGCTG
TCTCAATCGATACACAACGCATTGGCACGCAAGTGCTGGTGGACCACGGCGAGACGATTGTACTGGGCGGGATCTACCAG
CAACAACTTATCAGCCGAGTGAGTAAAGTGCCTATTCTGGGGGATATCCCATACTTAGGCTTTATGTTCAGAAGTACTTC
TGACAAAAATGAGCGACAGGAGCTACTCATTTTTGTTACGCCTAAGATAGTCTCCGAAGCGCTATAA

Upstream 100 bases:

>100_bases
AACTCCGCAAACTGTCGAAATAATAGAATTAATCCCAGATGGATCCGGCTGCTGGACTGAACGCAACAGCAGTATGGAAT
TAACGGGAGAATAATAAGAG

Downstream 100 bases:

>100_bases
ATTATTTAGGCCCCCAAAGCCAGCGAAATCCGCTGGCTTTGTCAGTTTAGTTGATACATTTTTGATAGAAATGCATTCCA
CGCTTGCCATAGATGGCACT

Product: type IV pilus secretin PilQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 688; Mature: 687

Protein sequence:

>688_residues
MTEGIMRSLTTPKASFKVMPLVKVIIGFVLIVGMTQHSYAANRLIDVKYHAVVDHQLELQLIFENDIKEPEIDLNASPAQ
IILGFDDSISALEKQTLPIKTVGVETVSTVPNGNNLQVFVGLNKVKPYQGKVVGNTYRLTINDEVASQGIAGENPFVNSI
ENIDFRRTADGGGELLVKLNNSSVAANVEQVGAKLELKLYNTDINSDFLYVMDVYDFATPVKSFETFKEDLTARFLIDID
GNYEYNYKQDGSLFKLTMKKTERMNIVKEDKKYDGRSLSLNFQNISVRTVLQIIADYNNFNLVTSDTVEGDITLRLDDVP
WDQALDLILQAKGLDKRIEGNILMVAPIEEIAIRESQELKNMQEVKELAPLYSEYLQINYAKAVDIAALLKGEDSSLLTS
RGSVAVDERTNTLLVKDTEETLENIHRLIEVLDIPIKQVLIEARMVTVKDDVSEDLGVRWGVTDQQGDKGTSGSLEGAGD
IANGIVPSLSDRLNVNLPAAVANPTSIAFHVAKLADGTVLDLELSALEQENKGEIIASPRITTSNQKAAFIEQGVEIPYV
EASSSGATTVTFKKAVLSLRVTPQITPDNRVILDLEITQDSQGKTVDTPTGQAVSIDTQRIGTQVLVDHGETIVLGGIYQ
QQLISRVSKVPILGDIPYLGFMFRSTSDKNERQELLIFVTPKIVSEAL

Sequences:

>Translated_688_residues
MTEGIMRSLTTPKASFKVMPLVKVIIGFVLIVGMTQHSYAANRLIDVKYHAVVDHQLELQLIFENDIKEPEIDLNASPAQ
IILGFDDSISALEKQTLPIKTVGVETVSTVPNGNNLQVFVGLNKVKPYQGKVVGNTYRLTINDEVASQGIAGENPFVNSI
ENIDFRRTADGGGELLVKLNNSSVAANVEQVGAKLELKLYNTDINSDFLYVMDVYDFATPVKSFETFKEDLTARFLIDID
GNYEYNYKQDGSLFKLTMKKTERMNIVKEDKKYDGRSLSLNFQNISVRTVLQIIADYNNFNLVTSDTVEGDITLRLDDVP
WDQALDLILQAKGLDKRIEGNILMVAPIEEIAIRESQELKNMQEVKELAPLYSEYLQINYAKAVDIAALLKGEDSSLLTS
RGSVAVDERTNTLLVKDTEETLENIHRLIEVLDIPIKQVLIEARMVTVKDDVSEDLGVRWGVTDQQGDKGTSGSLEGAGD
IANGIVPSLSDRLNVNLPAAVANPTSIAFHVAKLADGTVLDLELSALEQENKGEIIASPRITTSNQKAAFIEQGVEIPYV
EASSSGATTVTFKKAVLSLRVTPQITPDNRVILDLEITQDSQGKTVDTPTGQAVSIDTQRIGTQVLVDHGETIVLGGIYQ
QQLISRVSKVPILGDIPYLGFMFRSTSDKNERQELLIFVTPKIVSEAL
>Mature_687_residues
TEGIMRSLTTPKASFKVMPLVKVIIGFVLIVGMTQHSYAANRLIDVKYHAVVDHQLELQLIFENDIKEPEIDLNASPAQI
ILGFDDSISALEKQTLPIKTVGVETVSTVPNGNNLQVFVGLNKVKPYQGKVVGNTYRLTINDEVASQGIAGENPFVNSIE
NIDFRRTADGGGELLVKLNNSSVAANVEQVGAKLELKLYNTDINSDFLYVMDVYDFATPVKSFETFKEDLTARFLIDIDG
NYEYNYKQDGSLFKLTMKKTERMNIVKEDKKYDGRSLSLNFQNISVRTVLQIIADYNNFNLVTSDTVEGDITLRLDDVPW
DQALDLILQAKGLDKRIEGNILMVAPIEEIAIRESQELKNMQEVKELAPLYSEYLQINYAKAVDIAALLKGEDSSLLTSR
GSVAVDERTNTLLVKDTEETLENIHRLIEVLDIPIKQVLIEARMVTVKDDVSEDLGVRWGVTDQQGDKGTSGSLEGAGDI
ANGIVPSLSDRLNVNLPAAVANPTSIAFHVAKLADGTVLDLELSALEQENKGEIIASPRITTSNQKAAFIEQGVEIPYVE
ASSSGATTVTFKKAVLSLRVTPQITPDNRVILDLEITQDSQGKTVDTPTGQAVSIDTQRIGTQVLVDHGETIVLGGIYQQ
QLISRVSKVPILGDIPYLGFMFRSTSDKNERQELLIFVTPKIVSEAL

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=415, Percent_Identity=38.5542168674699, Blast_Score=266, Evalue=3e-72,
Organism=Escherichia coli, GI87082242, Length=382, Percent_Identity=29.3193717277487, Blast_Score=127, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 75782; Mature: 75651

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEGIMRSLTTPKASFKVMPLVKVIIGFVLIVGMTQHSYAANRLIDVKYHAVVDHQLELQ
CCCHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEEEEEECCEEEEE
LIFENDIKEPEIDLNASPAQIILGFDDSISALEKQTLPIKTVGVETVSTVPNGNNLQVFV
EEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEECCEEEEECCCCCCEEEEE
GLNKVKPYQGKVVGNTYRLTINDEVASQGIAGENPFVNSIENIDFRRTADGGGELLVKLN
EECCCCCCCCEEECCEEEEEECHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEC
NSSVAANVEQVGAKLELKLYNTDINSDFLYVMDVYDFATPVKSFETFKEDLTARFLIDID
CCCEECCHHHCCCEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHCCEEEEEEEEC
GNYEYNYKQDGSLFKLTMKKTERMNIVKEDKKYDGRSLSLNFQNISVRTVLQIIADYNNF
CCEEECCCCCCCEEEEEEHHHHHCCCEECCCCCCCCEEEEEECCCHHHHHHHHHHCCCCC
NLVTSDTVEGDITLRLDDVPWDQALDLILQAKGLDKRIEGNILMVAPIEEIAIRESQELK
EEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHCCHHHHH
NMQEVKELAPLYSEYLQINYAKAVDIAALLKGEDSSLLTSRGSVAVDERTNTLLVKDTEE
HHHHHHHHHHHHHHHHEEEHHHHHEEEEEECCCCCCEEECCCCEEEECCCCEEEEECHHH
TLENIHRLIEVLDIPIKQVLIEARMVTVKDDVSEDLGVRWGVTDQQGDKGTSGSLEGAGD
HHHHHHHHHHHHCCCHHHHHHHHHEEEEECCCCHHCCCEECCCCCCCCCCCCCCCCCCCH
IANGIVPSLSDRLNVNLPAAVANPTSIAFHVAKLADGTVLDLELSALEQENKGEIIASPR
HHCCCCCCCCCCEEECCCEEECCCCHHEEEEEECCCCEEEEEEEHHHCCCCCCCEEECCE
ITTSNQKAAFIEQGVEIPYVEASSSGATTVTFKKAVLSLRVTPQITPDNRVILDLEITQD
EECCCCCHHHHHCCCCCCEEECCCCCCEEEEEEEEEEEEEECCEECCCCEEEEEEEECCC
SQGKTVDTPTGQAVSIDTQRIGTQVLVDHGETIVLGGIYQQQLISRVSKVPILGDIPYLG
CCCCEECCCCCCEEEEEHHHCCCEEEEECCCEEEECCHHHHHHHHHHHCCCEEECCCHHE
FMFRSTSDKNERQELLIFVTPKIVSEAL
EEEECCCCCCCCEEEEEEECHHHHHHCC
>Mature Secondary Structure 
TEGIMRSLTTPKASFKVMPLVKVIIGFVLIVGMTQHSYAANRLIDVKYHAVVDHQLELQ
CCHHHHHHCCCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHCCEEEEEEEEEECCEEEEE
LIFENDIKEPEIDLNASPAQIILGFDDSISALEKQTLPIKTVGVETVSTVPNGNNLQVFV
EEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEECCEEEEECCCCCCEEEEE
GLNKVKPYQGKVVGNTYRLTINDEVASQGIAGENPFVNSIENIDFRRTADGGGELLVKLN
EECCCCCCCCEEECCEEEEEECHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEC
NSSVAANVEQVGAKLELKLYNTDINSDFLYVMDVYDFATPVKSFETFKEDLTARFLIDID
CCCEECCHHHCCCEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHCCEEEEEEEEC
GNYEYNYKQDGSLFKLTMKKTERMNIVKEDKKYDGRSLSLNFQNISVRTVLQIIADYNNF
CCEEECCCCCCCEEEEEEHHHHHCCCEECCCCCCCCEEEEEECCCHHHHHHHHHHCCCCC
NLVTSDTVEGDITLRLDDVPWDQALDLILQAKGLDKRIEGNILMVAPIEEIAIRESQELK
EEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHCCHHHHH
NMQEVKELAPLYSEYLQINYAKAVDIAALLKGEDSSLLTSRGSVAVDERTNTLLVKDTEE
HHHHHHHHHHHHHHHHEEEHHHHHEEEEEECCCCCCEEECCCCEEEECCCCEEEEECHHH
TLENIHRLIEVLDIPIKQVLIEARMVTVKDDVSEDLGVRWGVTDQQGDKGTSGSLEGAGD
HHHHHHHHHHHHCCCHHHHHHHHHEEEEECCCCHHCCCEECCCCCCCCCCCCCCCCCCCH
IANGIVPSLSDRLNVNLPAAVANPTSIAFHVAKLADGTVLDLELSALEQENKGEIIASPR
HHCCCCCCCCCCEEECCCEEECCCCHHEEEEEECCCCEEEEEEEHHHCCCCCCCEEECCE
ITTSNQKAAFIEQGVEIPYVEASSSGATTVTFKKAVLSLRVTPQITPDNRVILDLEITQD
EECCCCCHHHHHCCCCCCEEECCCCCCEEEEEEEEEEEEEECCEECCCCEEEEEEEECCC
SQGKTVDTPTGQAVSIDTQRIGTQVLVDHGETIVLGGIYQQQLISRVSKVPILGDIPYLG
CCCCEECCCCCCEEEEEHHHCCCEEEEECCCEEEECCHHHHHHHHHHHCCCEEECCCHHE
FMFRSTSDKNERQELLIFVTPKIVSEAL
EEEECCCCCCCCEEEEEEECHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]