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The map label for this gene is cinA [C]

Identifier: 157960052

GI number: 157960052

Start: 249650

End: 250924

Strand: Direct

Name: cinA [C]

Synonym: Spea_0223

Alternate gene names: 157960052

Gene position: 249650-250924 (Clockwise)

Preceding gene: 157960050

Following gene: 157960056

Centisome position: 4.82

GC content: 45.25

Gene sequence:

>1275_bases
ATGAAGCTAGAAATGATTTGTACGGGCGAAGAGGTGTTGGCTGGCCAGATAGTCGATACAAATGCTGCATGGTTCGGTAA
TACCATGATGGAACATGGTATCGAGTGTCAAAGGCGTGTGACAGTTGGTGATCGCTTAGAAGATCTCGTCTCAGTATTTA
AAGAACGCAGCCATGAGGCTGATGTGATTTTAGTTAATGGTGGTCTCGGACCGACAAGTGATGATCTCTCTGCTGAAGCG
ATGTCACTCGCTAAGGGAGAGGCCTTAGTCGAGAACGAAATTTGGCGAGAGAGGTTGGAAAATTGGTTTACCCGTAACGG
CCGAGTAATGGCGCTGAGTAATCTTAAGCAAGCTATGTTACCTGAGTCAGCCATTATGATAGATAATCCTGTTGGGACGG
CTTGTGGTTTCGCTGTAAAACTCAATCGTGCATGGTTATTTTTTACCCCTGGCGTCCCATTTGAATTTAAACAGATGGTC
TATGAACAGTTTATACCTTTCGTTAAGCAGCGATTTGATATTGCAGGTGATGTAGCGCTAAGGAAGCTCCTAACCTTAGG
TCAAGGAGAATCATCGCTTGCAGATACGCTCGAGCAGATAGATTTGCCTAGTGGGATTACCATAGGTTACCGCTCTTTTA
TGCCGCATATAGAGATAAAGCTATTCGCTCGTGGTGTAGGAGCAATTGCTCAGCTTGACAGACTCGAAGCGCAAATAAGA
TTTCTACTGGGCAATGCTATCGTTGCTTGTGATAGGAAAAGCTTAGCTGAAGAGATCCACTCTCTAATGGTAAATTCTGG
GCTAAGCCTCAGTACCGCGGAGTCTTGTACCGGTGGCATGATAGCAAGTCAACTGATCGACCTCTCTGGGAGTTCATCCT
ATTTAGATCAAGGTTTAGTGACTTATAGTAATGAGTCTAAGGTTCGAGTATTAGGTGTTAAGCCTGAGACATTAGACGAT
CACGGGGCAGTCTCTATCGCTACTGTAGAAGAGATGGCTAAGGGAGTAAGATCAATTCTTAATAGTGACTTTGCGCTAGC
GACAAGTGGCATAGCAGGCCCTACAGGTGGTACTGATGATAAGCCTGTTGGCACGGTTGCCATTGCTCTAGCGACGAAAG
GGGGTGTTTATAGTCAGATGATTAAGCTACCTCGACGTTCTCGCGAATTAGTGCGTAGTTTAAGTACTGCCGTCGCATTC
GATATGTTAAGAAGAGAGCTGTTAGGTGAGGCGGTTATCGTCGATTATGGTTCGATTGGCCGTTTCCAAAAATAA

Upstream 100 bases:

>100_bases
AGCATCTCCAAACTAATTGATGAAAATATCATAAGTGCGTATTGCTATTCGGGCTTAGCTTTCATAGTTTAGCTTCAATG
GAGACACTAAGGATTATGAA

Downstream 100 bases:

>100_bases
TGCATTTAGAATAAAAAGGCAGTATCAAGTGATACTGCCTTTTTGGTTTATGATGTCTAATCCGCAGAGAAGTTAACTAT
TCTTCGAATATCAGTACTAG

Product: competence/damage-inducible protein CinA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MKLEMICTGEEVLAGQIVDTNAAWFGNTMMEHGIECQRRVTVGDRLEDLVSVFKERSHEADVILVNGGLGPTSDDLSAEA
MSLAKGEALVENEIWRERLENWFTRNGRVMALSNLKQAMLPESAIMIDNPVGTACGFAVKLNRAWLFFTPGVPFEFKQMV
YEQFIPFVKQRFDIAGDVALRKLLTLGQGESSLADTLEQIDLPSGITIGYRSFMPHIEIKLFARGVGAIAQLDRLEAQIR
FLLGNAIVACDRKSLAEEIHSLMVNSGLSLSTAESCTGGMIASQLIDLSGSSSYLDQGLVTYSNESKVRVLGVKPETLDD
HGAVSIATVEEMAKGVRSILNSDFALATSGIAGPTGGTDDKPVGTVAIALATKGGVYSQMIKLPRRSRELVRSLSTAVAF
DMLRRELLGEAVIVDYGSIGRFQK

Sequences:

>Translated_424_residues
MKLEMICTGEEVLAGQIVDTNAAWFGNTMMEHGIECQRRVTVGDRLEDLVSVFKERSHEADVILVNGGLGPTSDDLSAEA
MSLAKGEALVENEIWRERLENWFTRNGRVMALSNLKQAMLPESAIMIDNPVGTACGFAVKLNRAWLFFTPGVPFEFKQMV
YEQFIPFVKQRFDIAGDVALRKLLTLGQGESSLADTLEQIDLPSGITIGYRSFMPHIEIKLFARGVGAIAQLDRLEAQIR
FLLGNAIVACDRKSLAEEIHSLMVNSGLSLSTAESCTGGMIASQLIDLSGSSSYLDQGLVTYSNESKVRVLGVKPETLDD
HGAVSIATVEEMAKGVRSILNSDFALATSGIAGPTGGTDDKPVGTVAIALATKGGVYSQMIKLPRRSRELVRSLSTAVAF
DMLRRELLGEAVIVDYGSIGRFQK
>Mature_424_residues
MKLEMICTGEEVLAGQIVDTNAAWFGNTMMEHGIECQRRVTVGDRLEDLVSVFKERSHEADVILVNGGLGPTSDDLSAEA
MSLAKGEALVENEIWRERLENWFTRNGRVMALSNLKQAMLPESAIMIDNPVGTACGFAVKLNRAWLFFTPGVPFEFKQMV
YEQFIPFVKQRFDIAGDVALRKLLTLGQGESSLADTLEQIDLPSGITIGYRSFMPHIEIKLFARGVGAIAQLDRLEAQIR
FLLGNAIVACDRKSLAEEIHSLMVNSGLSLSTAESCTGGMIASQLIDLSGSSSYLDQGLVTYSNESKVRVLGVKPETLDD
HGAVSIATVEEMAKGVRSILNSDFALATSGIAGPTGGTDDKPVGTVAIALATKGGVYSQMIKLPRRSRELVRSLSTAVAF
DMLRRELLGEAVIVDYGSIGRFQK

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family

Homologues:

Organism=Escherichia coli, GI1788583, Length=421, Percent_Identity=40.1425178147268, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI1789052, Length=154, Percent_Identity=43.5064935064935, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787818, Length=131, Percent_Identity=33.587786259542, Blast_Score=85, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323832, Length=205, Percent_Identity=25.8536585365854, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CINAL_SHEPA (A8GZ14)

Other databases:

- EMBL:   CP000851
- RefSeq:   YP_001500086.1
- ProteinModelPortal:   A8GZ14
- SMR:   A8GZ14
- STRING:   A8GZ14
- GeneID:   5664668
- GenomeReviews:   CP000851_GR
- KEGG:   spl:Spea_0223
- NMPDR:   fig|398579.3.peg.205
- eggNOG:   COG1058
- HOGENOM:   HBG449871
- OMA:   NPTVAPY
- ProtClustDB:   CLSK905663
- BioCyc:   SPEA398579:SPEA_0223-MONOMER
- HAMAP:   MF_00226_B
- InterPro:   IPR008136
- InterPro:   IPR008135
- InterPro:   IPR001453
- Gene3D:   G3DSA:3.40.980.10
- PIRSF:   PIRSF006728
- SMART:   SM00852
- TIGRFAMs:   TIGR00199
- TIGRFAMs:   TIGR00200

Pfam domain/function: PF02464 CinA; PF00994 MoCF_biosynth; SSF53218 MoCF_biosynth

EC number: NA

Molecular weight: Translated: 46031; Mature: 46031

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLEMICTGEEVLAGQIVDTNAAWFGNTMMEHGIECQRRVTVGDRLEDLVSVFKERSHEA
CEEEEEECCCHHHCCEEEECCCHHHCCHHHHCCCCHHHCCCHHHHHHHHHHHHHHCCCCC
DVILVNGGLGPTSDDLSAEAMSLAKGEALVENEIWRERLENWFTRNGRVMALSNLKQAML
CEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHC
PESAIMIDNPVGTACGFAVKLNRAWLFFTPGVPFEFKQMVYEQFIPFVKQRFDIAGDVAL
CCCEEEEECCCCCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
RKLLTLGQGESSLADTLEQIDLPSGITIGYRSFMPHIEIKLFARGVGAIAQLDRLEAQIR
HHHHHHCCCCHHHHHHHHHCCCCCCCEECHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHH
FLLGNAIVACDRKSLAEEIHSLMVNSGLSLSTAESCTGGMIASQLIDLSGSSSYLDQGLV
HHHCCHHEEECHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHCCCCHHHHHCCCE
TYSNESKVRVLGVKPETLDDHGAVSIATVEEMAKGVRSILNSDFALATSGIAGPTGGTDD
EECCCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCCC
KPVGTVAIALATKGGVYSQMIKLPRRSRELVRSLSTAVAFDMLRRELLGEAVIVDYGSIG
CCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
RFQK
CCCC
>Mature Secondary Structure
MKLEMICTGEEVLAGQIVDTNAAWFGNTMMEHGIECQRRVTVGDRLEDLVSVFKERSHEA
CEEEEEECCCHHHCCEEEECCCHHHCCHHHHCCCCHHHCCCHHHHHHHHHHHHHHCCCCC
DVILVNGGLGPTSDDLSAEAMSLAKGEALVENEIWRERLENWFTRNGRVMALSNLKQAML
CEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHC
PESAIMIDNPVGTACGFAVKLNRAWLFFTPGVPFEFKQMVYEQFIPFVKQRFDIAGDVAL
CCCEEEEECCCCCCCCEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHH
RKLLTLGQGESSLADTLEQIDLPSGITIGYRSFMPHIEIKLFARGVGAIAQLDRLEAQIR
HHHHHHCCCCHHHHHHHHHCCCCCCCEECHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHH
FLLGNAIVACDRKSLAEEIHSLMVNSGLSLSTAESCTGGMIASQLIDLSGSSSYLDQGLV
HHHCCHHEEECHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHCCCCHHHHHCCCE
TYSNESKVRVLGVKPETLDDHGAVSIATVEEMAKGVRSILNSDFALATSGIAGPTGGTDD
EECCCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHCCCHHEEECCCCCCCCCCCC
KPVGTVAIALATKGGVYSQMIKLPRRSRELVRSLSTAVAFDMLRRELLGEAVIVDYGSIG
CCCCEEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
RFQK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA