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The map label for this gene is argC

Identifier: 157960056

GI number: 157960056

Start: 255774

End: 256763

Strand: Direct

Name: argC

Synonym: Spea_0227

Alternate gene names: 157960056

Gene position: 255774-256763 (Clockwise)

Preceding gene: 157960052

Following gene: 157960057

Centisome position: 4.94

GC content: 46.06

Gene sequence:

>990_bases
ATGAAGAATATAGCCATTATTGGCGCCAGTGGGTACACCGGCGCACAGATCACCTCTCTTATAAATGCCGAAGCGAATTT
ATCAATTCAAGGCCTTTATGTTTCTGAAAGCAGCCTAGATAAGGGTAAGCCATTATCTGAGCTCTACCCTGCATATAGCC
ATATCTCACTGTGCCTTAATCCACTTTCTGAAGATGCAAAGCAAACCATAGTGGCCACTGCTGACGCCGTGGTGCTTGCG
ACCGATCATGCTGTGAGTTTGCATCTAGCAGCCTGGTTTTATCAGCAAGGTTTAGCCGTGTTTGATTTGAGTGGCGCTTA
CCGGTTTAGCGACGTAGCGCAATACCCTAAGTGGTATGGTTTTACTCATGAATATCCACAAGTATTGGCCGATGCAGTAT
ATGGTCTAGCCGAGTGGAATAGCGATCAAATAGCAGCGACTAAGATGATAGCCGTACCTGGCTGTTATCCAACGGCATCA
CTTATAGCATTGAAGCCCCTCTCTCATCTATTAACCGATGTATTGCCTGTGATTAATGCGGTAAGTGGTGTGACTGGTGC
AGGCAGAAAAGCTCAACTACATACAAGCTTTTGTGAGGTGAGCTTAACGCCCTATGGCGTACTCGCCCATAGGCATCAAC
CAGAGATTGCGACTCAACTAGGGCAAGAAGTTATCTTCACTCCTCATCTTGGCAACTTTAAGCGTGGGATCTTGGCTACG
ATTACAGTCAAGTTGAAGCCTGGCACCACTCTTAGTGATATTCAGCAGGCTTATCAATGTTACGACTCGGCCGAGCTTGT
CACGGTAAAACAGAATCAATTCCCTAAGGTAGATGATGTGGTGCAAACACCTCATTGCCATTTAGGGTGGAAATTTGACG
AGCAGACTGGATACCTAGTGGTAGCTAGCGCCATCGATAACTTAATGAAGGGCGCTGCAAGTCAAGCTCTTCAGTGCATA
AAGATTCACTTTGGTGAGTCTGTTAAGTAA

Upstream 100 bases:

>100_bases
AATCTTGTCATTAAATGGTGTTCAGCCAGGGCTTTAGTTGTGCCCACTCTTTTTTGTTTTGTCATCTAAATTCAAGATTA
AGGTTTTAAAGTCATAGACT

Downstream 100 bases:

>100_bases
CTGGTGTGGAGAATTGAGATGACTCAAACAGATCTAAACAACACAGAACAAAAGCCAGTTATGGTGCTTAAGGTCGGCGG
GGCTTTACTGCAGTGTGACA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MKNIAIIGASGYTGAQITSLINAEANLSIQGLYVSESSLDKGKPLSELYPAYSHISLCLNPLSEDAKQTIVATADAVVLA
TDHAVSLHLAAWFYQQGLAVFDLSGAYRFSDVAQYPKWYGFTHEYPQVLADAVYGLAEWNSDQIAATKMIAVPGCYPTAS
LIALKPLSHLLTDVLPVINAVSGVTGAGRKAQLHTSFCEVSLTPYGVLAHRHQPEIATQLGQEVIFTPHLGNFKRGILAT
ITVKLKPGTTLSDIQQAYQCYDSAELVTVKQNQFPKVDDVVQTPHCHLGWKFDEQTGYLVVASAIDNLMKGAASQALQCI
KIHFGESVK

Sequences:

>Translated_329_residues
MKNIAIIGASGYTGAQITSLINAEANLSIQGLYVSESSLDKGKPLSELYPAYSHISLCLNPLSEDAKQTIVATADAVVLA
TDHAVSLHLAAWFYQQGLAVFDLSGAYRFSDVAQYPKWYGFTHEYPQVLADAVYGLAEWNSDQIAATKMIAVPGCYPTAS
LIALKPLSHLLTDVLPVINAVSGVTGAGRKAQLHTSFCEVSLTPYGVLAHRHQPEIATQLGQEVIFTPHLGNFKRGILAT
ITVKLKPGTTLSDIQQAYQCYDSAELVTVKQNQFPKVDDVVQTPHCHLGWKFDEQTGYLVVASAIDNLMKGAASQALQCI
KIHFGESVK
>Mature_329_residues
MKNIAIIGASGYTGAQITSLINAEANLSIQGLYVSESSLDKGKPLSELYPAYSHISLCLNPLSEDAKQTIVATADAVVLA
TDHAVSLHLAAWFYQQGLAVFDLSGAYRFSDVAQYPKWYGFTHEYPQVLADAVYGLAEWNSDQIAATKMIAVPGCYPTAS
LIALKPLSHLLTDVLPVINAVSGVTGAGRKAQLHTSFCEVSLTPYGVLAHRHQPEIATQLGQEVIFTPHLGNFKRGILAT
ITVKLKPGTTLSDIQQAYQCYDSAELVTVKQNQFPKVDDVVQTPHCHLGWKFDEQTGYLVVASAIDNLMKGAASQALQCI
KIHFGESVK

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=332, Percent_Identity=50.3012048192771, Blast_Score=302, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6320913, Length=337, Percent_Identity=31.1572700296736, Blast_Score=120, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_SHEPA (A8GZ18)

Other databases:

- EMBL:   CP000851
- RefSeq:   YP_001500090.1
- ProteinModelPortal:   A8GZ18
- SMR:   A8GZ18
- STRING:   A8GZ18
- GeneID:   5660627
- GenomeReviews:   CP000851_GR
- KEGG:   spl:Spea_0227
- NMPDR:   fig|398579.3.peg.209
- eggNOG:   COG0002
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- BioCyc:   SPEA398579:SPEA_0227-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 35565; Mature: 35565

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 155-155

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIAIIGASGYTGAQITSLINAEANLSIQGLYVSESSLDKGKPLSELYPAYSHISLCLN
CCCEEEEECCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
PLSEDAKQTIVATADAVVLATDHAVSLHLAAWFYQQGLAVFDLSGAYRFSDVAQYPKWYG
HHHHHHHHHHHEECCEEEEEECCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHCHHHCC
FTHEYPQVLADAVYGLAEWNSDQIAATKMIAVPGCYPTASLIALKPLSHLLTDVLPVINA
CCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VSGVTGAGRKAQLHTSFCEVSLTPYGVLAHRHQPEIATQLGQEVIFTPHLGNFKRGILAT
HCCCCCCCCCEEEEEHEEEEECCCHHEECCCCCCHHHHHCCCEEEECCCCCCCCCCEEEE
ITVKLKPGTTLSDIQQAYQCYDSAELVTVKQNQFPKVDDVVQTPHCHLGWKFDEQTGYLV
EEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCCEECEEECCCCCEEE
VASAIDNLMKGAASQALQCIKIHFGESVK
EHHHHHHHHHHHHHHHHHHHHEECCCCCC
>Mature Secondary Structure
MKNIAIIGASGYTGAQITSLINAEANLSIQGLYVSESSLDKGKPLSELYPAYSHISLCLN
CCCEEEEECCCCCHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
PLSEDAKQTIVATADAVVLATDHAVSLHLAAWFYQQGLAVFDLSGAYRFSDVAQYPKWYG
HHHHHHHHHHHEECCEEEEEECCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHCHHHCC
FTHEYPQVLADAVYGLAEWNSDQIAATKMIAVPGCYPTASLIALKPLSHLLTDVLPVINA
CCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VSGVTGAGRKAQLHTSFCEVSLTPYGVLAHRHQPEIATQLGQEVIFTPHLGNFKRGILAT
HCCCCCCCCCEEEEEHEEEEECCCHHEECCCCCCHHHHHCCCEEEECCCCCCCCCCEEEE
ITVKLKPGTTLSDIQQAYQCYDSAELVTVKQNQFPKVDDVVQTPHCHLGWKFDEQTGYLV
EEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHCCCCCEECEEECCCCCEEE
VASAIDNLMKGAASQALQCIKIHFGESVK
EHHHHHHHHHHHHHHHHHHHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA