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The map label for this gene is tlpA [H]

Identifier: 157960050

GI number: 157960050

Start: 233942

End: 234538

Strand: Direct

Name: tlpA [H]

Synonym: Spea_0221

Alternate gene names: 157960050

Gene position: 233942-234538 (Clockwise)

Preceding gene: 157960049

Following gene: 157960052

Centisome position: 4.52

GC content: 42.55

Gene sequence:

>597_bases
ATGAGATCGACCATAGTGGGTTTAGCTGCAGCAACCATGTTGTTTGCTGCAGGCGCGCAAGCTTATCCAGGAATGGAAAA
GCAAGCTGAAAAACAAGTCCAATCTAGTGTCGATCTAATTAGTGTTCTTCCTAAGCCATTTCCGATCGAAGCCGTAGCTT
TTAAAAACAGCGAAGGTGCTTCCGTCGACTTTAGCCAATATAAAGGTAAAGTCATTATGGTAAACATGTGGGCGACTTGG
TGTCCTCCGTGTGTTAGGGAGTTGCCTGCAATAAGCCGCTTCTCTGCCAAGATCGGATCTGATGACTTTGAGGTGTTACC
CGTTTCTATTGATCTCGAAGGTAACAAGCAAGTAGAGCCGTTCTTGAAGTCATTAGGTATGGAAGACTTTAATACCTATT
ATGATAAAGAACAGAAGTTGGGTAATGTCTTTCCTTTAGACACAATCCCAGCGACCTTTATCCTTAATAGAGAAGGTGAG
TTAATTGCTTTCGTTCGTACCTTCGTAGATTGGGACGACGATAAAGCGGTAACACTTATTAAAGGGTTTCTTGCAGAACC
TCAACTATCAAGTTCTCTTACTAAGAACGCAGATTAG

Upstream 100 bases:

>100_bases
TCTTTTTCATTCGTAAACAGCGTATAGCAGAGGCGACTAACCAAGAGCTATCTACTGAAGAGCAAGAAGAACTCGATCGT
CTATTAAAGAGAGACGCTAA

Downstream 100 bases:

>100_bases
ATTTAATAGTGTTATTAATGATAAAAAAGGGGCTTTTAGCCCCTTTTTTGCACGTATCGTTTGATTACTATTCGCTTGAT
TCGAAAAAGCTAATTTAATT

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MRSTIVGLAAATMLFAAGAQAYPGMEKQAEKQVQSSVDLISVLPKPFPIEAVAFKNSEGASVDFSQYKGKVIMVNMWATW
CPPCVRELPAISRFSAKIGSDDFEVLPVSIDLEGNKQVEPFLKSLGMEDFNTYYDKEQKLGNVFPLDTIPATFILNREGE
LIAFVRTFVDWDDDKAVTLIKGFLAEPQLSSSLTKNAD

Sequences:

>Translated_198_residues
MRSTIVGLAAATMLFAAGAQAYPGMEKQAEKQVQSSVDLISVLPKPFPIEAVAFKNSEGASVDFSQYKGKVIMVNMWATW
CPPCVRELPAISRFSAKIGSDDFEVLPVSIDLEGNKQVEPFLKSLGMEDFNTYYDKEQKLGNVFPLDTIPATFILNREGE
LIAFVRTFVDWDDDKAVTLIKGFLAEPQLSSSLTKNAD
>Mature_198_residues
MRSTIVGLAAATMLFAAGAQAYPGMEKQAEKQVQSSVDLISVLPKPFPIEAVAFKNSEGASVDFSQYKGKVIMVNMWATW
CPPCVRELPAISRFSAKIGSDDFEVLPVSIDLEGNKQVEPFLKSLGMEDFNTYYDKEQKLGNVFPLDTIPATFILNREGE
LIAFVRTFVDWDDDKAVTLIKGFLAEPQLSSSLTKNAD

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21824; Mature: 21824

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSTIVGLAAATMLFAAGAQAYPGMEKQAEKQVQSSVDLISVLPKPFPIEAVAFKNSEGA
CCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCC
SVDFSQYKGKVIMVNMWATWCPPCVRELPAISRFSAKIGSDDFEVLPVSIDLEGNKQVEP
EEEHHHHCCEEEEEECCCHHCCHHHHHCCHHHHHHHHCCCCCCEEEEEEEECCCCCCHHH
FLKSLGMEDFNTYYDKEQKLGNVFPLDTIPATFILNREGELIAFVRTFVDWDDDKAVTLI
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCHHHHH
KGFLAEPQLSSSLTKNAD
HHHHCCCCHHHHHCCCCC
>Mature Secondary Structure
MRSTIVGLAAATMLFAAGAQAYPGMEKQAEKQVQSSVDLISVLPKPFPIEAVAFKNSEGA
CCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCC
SVDFSQYKGKVIMVNMWATWCPPCVRELPAISRFSAKIGSDDFEVLPVSIDLEGNKQVEP
EEEHHHHCCEEEEEECCCHHCCHHHHHCCHHHHHHHHCCCCCCEEEEEEEECCCCCCHHH
FLKSLGMEDFNTYYDKEQKLGNVFPLDTIPATFILNREGELIAFVRTFVDWDDDKAVTLI
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCHHHHHHHHCCCCCCHHHHH
KGFLAEPQLSSSLTKNAD
HHHHCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]