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The map label for this gene is 157825887

Identifier: 157825887

GI number: 157825887

Start: 745747

End: 746091

Strand: Reverse

Name: 157825887

Synonym: A1C_04130

Alternate gene names: NA

Gene position: 746091-745747 (Counterclockwise)

Preceding gene: 157825888

Following gene: 157825884

Centisome position: 60.61

GC content: 26.38

Gene sequence:

>345_bases
ATGACAGTAACAATAACCAAACAAGAGCTGCGTCTTTATTTCAAAGAATTTTTCATAAAAAACCAAAATGAGATTAATTA
CGACTTATTCAAAAACTCCCTAATCAATAAAATTAACCTGTTATTAAAGGAGTTAAAAGTACAAACAATTGGTCTATATT
ATCCTCTAAAATACGAAATTAATTTACTTGCAATAACAAACTTACATCCTGAAATAAAATTTTTCCTACCAAAAATTATA
GCAGATGAAATCAAATATTGTTCATATAAATCCAATGATGAATTAGTGCTAGGTGCATTTAAAACCTATGAGCCTCTAAA
TAATGATTTTTTATTCCTGAGTTAG

Upstream 100 bases:

>100_bases
TAAATGTTTATTTTCAAATATTGAATGTAATTTTTGTACTAATATTAAAGTTATTTTCTGTGTTCCCGCCTACGTGAGAA
TGAAATAAAGGAGTGCTGGA

Downstream 100 bases:

>100_bases
TATTATCCCAGGGCGGGCATTTAGTAATGAGTATTACAGACTTGGATACGGCACAGGACATTTTGATCGATATCTTAATA
ATAACCAAAATATCTTGGCT

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: ADP; phosphate; 5,10-methenyltetrahydrofolate

Alternate protein names: Porphobilinogen Deaminase; 10-Methenyltetrahydrofolate Synthetase.

Number of amino acids: Translated: 114; Mature: 113

Protein sequence:

>114_residues
MTVTITKQELRLYFKEFFIKNQNEINYDLFKNSLINKINLLLKELKVQTIGLYYPLKYEINLLAITNLHPEIKFFLPKII
ADEIKYCSYKSNDELVLGAFKTYEPLNNDFLFLS

Sequences:

>Translated_114_residues
MTVTITKQELRLYFKEFFIKNQNEINYDLFKNSLINKINLLLKELKVQTIGLYYPLKYEINLLAITNLHPEIKFFLPKII
ADEIKYCSYKSNDELVLGAFKTYEPLNNDFLFLS
>Mature_113_residues
TVTITKQELRLYFKEFFIKNQNEINYDLFKNSLINKINLLLKELKVQTIGLYYPLKYEINLLAITNLHPEIKFFLPKIIA
DEIKYCSYKSNDELVLGAFKTYEPLNNDFLFLS

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 6.3.3.2

Molecular weight: Translated: 13580; Mature: 13449

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTITKQELRLYFKEFFIKNQNEINYDLFKNSLINKINLLLKELKVQTIGLYYPLKYEI
CEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECEEEEE
NLLAITNLHPEIKFFLPKIIADEIKYCSYKSNDELVLGAFKTYEPLNNDFLFLS
EEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEC
>Mature Secondary Structure 
TVTITKQELRLYFKEFFIKNQNEINYDLFKNSLINKINLLLKELKVQTIGLYYPLKYEI
EEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECEEEEE
NLLAITNLHPEIKFFLPKIIADEIKYCSYKSNDELVLGAFKTYEPLNNDFLFLS
EEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; 5-formyltetrahydrofolate

Specific reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA