Click here to switch to the map view.

The map label for this gene is lrp [H]

Identifier: 157372679

GI number: 157372679

Start: 4919559

End: 4920026

Strand: Reverse

Name: lrp [H]

Synonym: Spro_4446

Alternate gene names: 157372679

Gene position: 4920026-4919559 (Counterclockwise)

Preceding gene: 157372681

Following gene: 157372678

Centisome position: 90.29

GC content: 56.62

Gene sequence:

>468_bases
ATGTACAACATTGACGATTTTGATATGAAAATCCTGACGCTGCTACAGGCCAATGGCCGTCTGACCAATCAGGAACTGAG
CGATCTGGTGGGGTTGTCGGCCTCCCAGTGTTCCCGGCGGCGCATCAGTCTGGAGCAGGCACAGCTGATCCGCGGTTACC
ATGCACGGCTGGCACCGGAGGCCGTCGGGCTGGGGCTGGTGGGGCTGATAGAAGTGAGCCTGACTCACCATGCCCAAGAG
CAGATCGACAGTTTCCACCAGATGCTGGAAGAAGTGGACGCCATTCTTGACGCCTATAAAACTACCGGCGATGCTGATTA
TCTGCTGAAGGTGGCGGTGGCGGACCTGCCGGCGCTGGACGACTTTATCAGTCAGACGCTGTCGCGGCATAAAAGCGTGG
CGCATATCAAAACGGCGGTGGTGCTCAACCGAATCAAGGAAAACGGTTTGTTGCCGGTTGCGAGATAA

Upstream 100 bases:

>100_bases
CTGCTGTGCGCTTCACAACCTCGGTGGGGGAAGGGTATCCACAGTCAAAAAACTGATAGGCTGTAACGTCAACATTTATT
AACACAGTTTACAGGTGGCT

Downstream 100 bases:

>100_bases
AGCTCAAACTGAACGGCCTTTTCCGTCTATATTAGAGCCTGATGCTGTGCCCCGAACCCTAATAATCCAGGAGAACAACC
CGTGTTTCAGAACGTTGATG

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MYNIDDFDMKILTLLQANGRLTNQELSDLVGLSASQCSRRRISLEQAQLIRGYHARLAPEAVGLGLVGLIEVSLTHHAQE
QIDSFHQMLEEVDAILDAYKTTGDADYLLKVAVADLPALDDFISQTLSRHKSVAHIKTAVVLNRIKENGLLPVAR

Sequences:

>Translated_155_residues
MYNIDDFDMKILTLLQANGRLTNQELSDLVGLSASQCSRRRISLEQAQLIRGYHARLAPEAVGLGLVGLIEVSLTHHAQE
QIDSFHQMLEEVDAILDAYKTTGDADYLLKVAVADLPALDDFISQTLSRHKSVAHIKTAVVLNRIKENGLLPVAR
>Mature_155_residues
MYNIDDFDMKILTLLQANGRLTNQELSDLVGLSASQCSRRRISLEQAQLIRGYHARLAPEAVGLGLVGLIEVSLTHHAQE
QIDSFHQMLEEVDAILDAYKTTGDADYLLKVAVADLPALDDFISQTLSRHKSVAHIKTAVVLNRIKENGLLPVAR

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=149, Percent_Identity=34.2281879194631, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=30, Blast_Score=89, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17146; Mature: 17146

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNIDDFDMKILTLLQANGRLTNQELSDLVGLSASQCSRRRISLEQAQLIRGYHARLAPE
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHH
AVGLGLVGLIEVSLTHHAQEQIDSFHQMLEEVDAILDAYKTTGDADYLLKVAVADLPALD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHH
DFISQTLSRHKSVAHIKTAVVLNRIKENGLLPVAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MYNIDDFDMKILTLLQANGRLTNQELSDLVGLSASQCSRRRISLEQAQLIRGYHARLAPE
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCHH
AVGLGLVGLIEVSLTHHAQEQIDSFHQMLEEVDAILDAYKTTGDADYLLKVAVADLPALD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHH
DFISQTLSRHKSVAHIKTAVVLNRIKENGLLPVAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]