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The map label for this gene is yphH [H]

Identifier: 157372465

GI number: 157372465

Start: 4694577

End: 4695779

Strand: Direct

Name: yphH [H]

Synonym: Spro_4232

Alternate gene names: 157372465

Gene position: 4694577-4695779 (Clockwise)

Preceding gene: 157372453

Following gene: 157372466

Centisome position: 86.16

GC content: 56.86

Gene sequence:

>1203_bases
ATGGCATTGCAAGGTTTGAATAACCAGCGGGTGCGTAATTTTAATAAACGGGTGTTATGTGCACTGCTGTACCGGGAAAA
GGTCGCCAGTAAGTCGACGCTGGCGCGGCTTTCGCAGCTGTCTATTCCTGCGGTCGGCAAAATTCTCGACGAACTGCAGG
AAGAGCAGCGGGTAGAACACGACCCGCACAACCTGCACAGCCGCGGTTTGGGTGGCGGCAGTTACCGCATCGCCGCCGCC
GGGCAACGCATCCTGTGCCTGAATGTCTCCCCTTATCTGATTGAAAGCATCGTGGTGGATGGCCTGATGACGCCTTGCAG
CGCCTTCACCCCGCAGCCGATCGTCGCCACTACGCCGCAGGCGATGCTGCAGGAAATGGTGCAAATCTATCATCTGCACA
GCCGCCAGCAGGGCACGCCACTGAAGATTGCGCTGTCGATCCACGGCCAGGTCAATCCGCTGACCGGGGTGTCCCAACGT
ATGCCACAGGCCCCGTGGGAAGGCCCGGTAGAGATAAAATACCTGCTGGAAGAGCGTCTGAAGACCGAGGTTTTGATCGA
TAACGACTGCGTGATGCTGGGGCTGGCGGAAAAGTGGCAAAATAACGCCAATCTGCAGGACTTTTGCGTGATTAACGTCG
ATTACGGCATAGGTTCATCATTTGTGATTAACCAGCAGATTTACCGGGGCAGCCTGTTTGGCAGCGGTCAAATCGGCCAT
ACCATTGTCGATCCCGATGGCGGCCTTTGCTCCTGTGGCCGTTACGGCTGTCTGGAAACCATCGCTTCGCTGTCGGCGCT
GAAGAAAAAGGCCCGCATTCAGCTCAAGGTCGCTCCCTGGGCACAACAGGAAGGCGAAAGGATTAAAACCCCCACCACCG
CCGACCTGATTGCCCGTTATCATCAGGGCGATGCTGCGTTGCAGGTGCTGGTGCAACGCGCCGCCCAGGCGATTGGCCTG
AGCCTGTATAACTTCCTTAATATCCTCAATATCAACCGTATCTATCTGTACGGGCGCAGCTGTGGATTTGGTCAGGCCTG
GCTGGACACCATCATCAGTCAGACCGGTTTTAACCCTTTCGACCGGCACGACCAGATCCAGGCCCAGGCCACGCATATCG
GCTTTGGCCAACTGACGCGCGCGCAGCAGGTGACGGGGATAGGCTATCTGTATGTCGAACAGGCACTGACGGAGATGCTA
TGA

Upstream 100 bases:

>100_bases
TCTCTAAAAATACTGAACATTGCGTTTCAGGCAGTCTAGATGACGGAATTGATGACTTTATGCGCTACCATCACGCAATA
CACTAAACGGGGTTTAATAA

Downstream 100 bases:

>100_bases
TGCCCGACTTTATCCCAGTAAAAACAATACGGAGCACCATGAACCCCACTCTACGACTCTGGTCACGCGCAGGCATTGTC
TGCCTGATGCTGATCCTGGC

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MALQGLNNQRVRNFNKRVLCALLYREKVASKSTLARLSQLSIPAVGKILDELQEEQRVEHDPHNLHSRGLGGGSYRIAAA
GQRILCLNVSPYLIESIVVDGLMTPCSAFTPQPIVATTPQAMLQEMVQIYHLHSRQQGTPLKIALSIHGQVNPLTGVSQR
MPQAPWEGPVEIKYLLEERLKTEVLIDNDCVMLGLAEKWQNNANLQDFCVINVDYGIGSSFVINQQIYRGSLFGSGQIGH
TIVDPDGGLCSCGRYGCLETIASLSALKKKARIQLKVAPWAQQEGERIKTPTTADLIARYHQGDAALQVLVQRAAQAIGL
SLYNFLNILNINRIYLYGRSCGFGQAWLDTIISQTGFNPFDRHDQIQAQATHIGFGQLTRAQQVTGIGYLYVEQALTEML

Sequences:

>Translated_400_residues
MALQGLNNQRVRNFNKRVLCALLYREKVASKSTLARLSQLSIPAVGKILDELQEEQRVEHDPHNLHSRGLGGGSYRIAAA
GQRILCLNVSPYLIESIVVDGLMTPCSAFTPQPIVATTPQAMLQEMVQIYHLHSRQQGTPLKIALSIHGQVNPLTGVSQR
MPQAPWEGPVEIKYLLEERLKTEVLIDNDCVMLGLAEKWQNNANLQDFCVINVDYGIGSSFVINQQIYRGSLFGSGQIGH
TIVDPDGGLCSCGRYGCLETIASLSALKKKARIQLKVAPWAQQEGERIKTPTTADLIARYHQGDAALQVLVQRAAQAIGL
SLYNFLNILNINRIYLYGRSCGFGQAWLDTIISQTGFNPFDRHDQIQAQATHIGFGQLTRAQQVTGIGYLYVEQALTEML
>Mature_399_residues
ALQGLNNQRVRNFNKRVLCALLYREKVASKSTLARLSQLSIPAVGKILDELQEEQRVEHDPHNLHSRGLGGGSYRIAAAG
QRILCLNVSPYLIESIVVDGLMTPCSAFTPQPIVATTPQAMLQEMVQIYHLHSRQQGTPLKIALSIHGQVNPLTGVSQRM
PQAPWEGPVEIKYLLEERLKTEVLIDNDCVMLGLAEKWQNNANLQDFCVINVDYGIGSSFVINQQIYRGSLFGSGQIGHT
IVDPDGGLCSCGRYGCLETIASLSALKKKARIQLKVAPWAQQEGERIKTPTTADLIARYHQGDAALQVLVQRAAQAIGLS
LYNFLNILNINRIYLYGRSCGFGQAWLDTIISQTGFNPFDRHDQIQAQATHIGFGQLTRAQQVTGIGYLYVEQALTEML

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=205, Percent_Identity=30.7317073170732, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI298566325, Length=205, Percent_Identity=30.7317073170732, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI4885285, Length=205, Percent_Identity=30.7317073170732, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI190014632, Length=205, Percent_Identity=30.7317073170732, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI87082127, Length=396, Percent_Identity=60.3535353535353, Blast_Score=480, Evalue=1e-137,
Organism=Escherichia coli, GI1786891, Length=235, Percent_Identity=27.2340425531915, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787878, Length=374, Percent_Identity=23.2620320855615, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44253; Mature: 44121

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALQGLNNQRVRNFNKRVLCALLYREKVASKSTLARLSQLSIPAVGKILDELQEEQRVEH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
DPHNLHSRGLGGGSYRIAAAGQRILCLNVSPYLIESIVVDGLMTPCSAFTPQPIVATTPQ
CCCHHHHCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEECCHH
AMLQEMVQIYHLHSRQQGTPLKIALSIHGQVNPLTGVSQRMPQAPWEGPVEIKYLLEERL
HHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHH
KTEVLIDNDCVMLGLAEKWQNNANLQDFCVINVDYGIGSSFVINQQIYRGSLFGSGQIGH
HHEEEECCCEEEEEEHHHHCCCCCCCEEEEEEECCCCCCCEEEEHHHHCCCCCCCCCCCC
TIVDPDGGLCSCGRYGCLETIASLSALKKKARIQLKVAPWAQQEGERIKTPTTADLIARY
EEECCCCCEECCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCHHHHHHHH
HQGDAALQVLVQRAAQAIGLSLYNFLNILNINRIYLYGRSCGFGQAWLDTIISQTGFNPF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCC
DRHDQIQAQATHIGFGQLTRAQQVTGIGYLYVEQALTEML
CCCCHHHHHHEECCHHHHHHHHHHCCCHHHHHHHHHHHHC
>Mature Secondary Structure 
ALQGLNNQRVRNFNKRVLCALLYREKVASKSTLARLSQLSIPAVGKILDELQEEQRVEH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
DPHNLHSRGLGGGSYRIAAAGQRILCLNVSPYLIESIVVDGLMTPCSAFTPQPIVATTPQ
CCCHHHHCCCCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEECCHH
AMLQEMVQIYHLHSRQQGTPLKIALSIHGQVNPLTGVSQRMPQAPWEGPVEIKYLLEERL
HHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHH
KTEVLIDNDCVMLGLAEKWQNNANLQDFCVINVDYGIGSSFVINQQIYRGSLFGSGQIGH
HHEEEECCCEEEEEEHHHHCCCCCCCEEEEEEECCCCCCCEEEEHHHHCCCCCCCCCCCC
TIVDPDGGLCSCGRYGCLETIASLSALKKKARIQLKVAPWAQQEGERIKTPTTADLIARY
EEECCCCCEECCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCHHHHHHHH
HQGDAALQVLVQRAAQAIGLSLYNFLNILNINRIYLYGRSCGFGQAWLDTIISQTGFNPF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCCC
DRHDQIQAQATHIGFGQLTRAQQVTGIGYLYVEQALTEML
CCCCHHHHHHEECCHHHHHHHHHHCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]