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The map label for this gene is yhdI [H]

Identifier: 157372453

GI number: 157372453

Start: 4678925

End: 4680421

Strand: Direct

Name: yhdI [H]

Synonym: Spro_4220

Alternate gene names: 157372453

Gene position: 4678925-4680421 (Clockwise)

Preceding gene: 157372449

Following gene: 157372465

Centisome position: 85.87

GC content: 53.24

Gene sequence:

>1497_bases
ATGTGGGAATTAGAGCTCGACAGAGTCTGTGATACGCCCCTGCAATTGCAGATTTTTCAATACTATTATCAGGCCATCAC
ACGTGGTAACTACGTTTGCGGTGATATGCTGCCTTCTATTCGTAAGCTGGCCGGCAAGCTGCAGGTTGCACGCATCACCG
TGGTGCTGGCCTATGAAAAGTTGGTGATTGGCGGCTACATTAAAAGCCGACCGGGCATTGGTTACCAGGTCGTATTTGAC
CGTCAGGTAAAACCCGTCCGGCACATTCCCTCTTACTTCAAAGGACCGGCCCCCACCCGTCTGTTGACCGCAGAGGTGCC
CGGCGATCTCTACAGTCAGCCGACGTCCGAACTTTATTGCCGCATGAGCATTCCCGATCCAAACGCTTTCCCTTGGGCAA
GCTGGCGCAAATGGAACAACTCACCGTCCTGTCTCAAAGAACAACTGGTGACGCGCTATCACTCTCCTCATGGGCTACTG
CCGTTACGCCAGGAGATCGCACGCTATTTACACCTCTCTCGCAGCATCGAGATCCGTCCAGAAAATATCATCATTACCAA
TGGCGTTCAGGAAGGGTTATCACTCTTGAGCCAGCTCTTTGTTCTCAAGCGAACGACGTCGTCCCATATCCCCTGCCATA
TTGTGACCGAATCGCCCTGTTATTCCGGCGCCTGGCATCTGTTCAATTATTACGGTGCGCAGGTCACCACGCTGGACGTC
GACAAACAGGGCATGTGCGTATCACATCTTCCGGAGCGTTCCACACAATTGTGCTATGTCACGCCCTCGCACCAGTATCC
TCTGGGTAGCCAACTTTCTCTCTCGCGGCGCAAAACCTTGCTGCTTTGGGCACAAAGGGTGGGCGCTTACGTCATCGAGG
ATGATTATGATGCGGTTTTTTCCTGGGGACAGAAACCTCTGCCTCCGCTGAAAGCGATGGACAGCCAGGATCGGGTAATT
TATGCCGGCACCTTTTCAAAAACCCTGGGGCCAGGGATCCGCTTGGGCTATTTGGTCTGTCCCGATGCCATTTTGCCCTC
AGTACAGAATATGAAGGCACTAAGCAACAGCGGGAGTAATTGGTTATTGCAGCAATTCCTGGCGGAGTTTATGCACAGTC
AGGTGTTTTATACCCACTTGAGCAAATTGACCTGCGAGTACGAGATGCGCCAGACCCTATTGCGTAAAGGGCTAAAACGT
CTGTTTCCCGAAGGGCAACTATGGGGTCACGCCGCCGGGCTGCATCTGACATTGATCACATCCATGACCGACGATGTTAT
TCAACGGCTTCGGCAGCGCTGCCTCCAGGCCGGGGTCCGCTTCGACACCTTGCGTGAGCTGGAAAACGGCTCGGAAACCA
CCTGGAGAGCGGGTGGCCACTCGTCGCCCATTTTCTTTGGCTTTGGCAATCTGAACTCGCAGCAGTTGAAAAAAGTCCTG
TTGGTGATCGAGCAACAGTTACTGTACCTGGATCAGGAGCACGGATCGCTGTACTGA

Upstream 100 bases:

>100_bases
CAGTAATAAGGCCAGATGACACATTTTGTTTAGGGTCAATTATTGCCGTACGCGGTTAGCGTAAGGTGCAGGAGCTGAAA
GTTTGCGACAAAGGGATTTT

Downstream 100 bases:

>100_bases
ACCGCCCCCCCGTTCGCGAGTTACAGCTGCTCACCGTGGCTGGCGATCACCCGCTGATACCAGCCAAAACTCTGCTTCTT
CTTGCGCGCCAGATTGTTGT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MWELELDRVCDTPLQLQIFQYYYQAITRGNYVCGDMLPSIRKLAGKLQVARITVVLAYEKLVIGGYIKSRPGIGYQVVFD
RQVKPVRHIPSYFKGPAPTRLLTAEVPGDLYSQPTSELYCRMSIPDPNAFPWASWRKWNNSPSCLKEQLVTRYHSPHGLL
PLRQEIARYLHLSRSIEIRPENIIITNGVQEGLSLLSQLFVLKRTTSSHIPCHIVTESPCYSGAWHLFNYYGAQVTTLDV
DKQGMCVSHLPERSTQLCYVTPSHQYPLGSQLSLSRRKTLLLWAQRVGAYVIEDDYDAVFSWGQKPLPPLKAMDSQDRVI
YAGTFSKTLGPGIRLGYLVCPDAILPSVQNMKALSNSGSNWLLQQFLAEFMHSQVFYTHLSKLTCEYEMRQTLLRKGLKR
LFPEGQLWGHAAGLHLTLITSMTDDVIQRLRQRCLQAGVRFDTLRELENGSETTWRAGGHSSPIFFGFGNLNSQQLKKVL
LVIEQQLLYLDQEHGSLY

Sequences:

>Translated_498_residues
MWELELDRVCDTPLQLQIFQYYYQAITRGNYVCGDMLPSIRKLAGKLQVARITVVLAYEKLVIGGYIKSRPGIGYQVVFD
RQVKPVRHIPSYFKGPAPTRLLTAEVPGDLYSQPTSELYCRMSIPDPNAFPWASWRKWNNSPSCLKEQLVTRYHSPHGLL
PLRQEIARYLHLSRSIEIRPENIIITNGVQEGLSLLSQLFVLKRTTSSHIPCHIVTESPCYSGAWHLFNYYGAQVTTLDV
DKQGMCVSHLPERSTQLCYVTPSHQYPLGSQLSLSRRKTLLLWAQRVGAYVIEDDYDAVFSWGQKPLPPLKAMDSQDRVI
YAGTFSKTLGPGIRLGYLVCPDAILPSVQNMKALSNSGSNWLLQQFLAEFMHSQVFYTHLSKLTCEYEMRQTLLRKGLKR
LFPEGQLWGHAAGLHLTLITSMTDDVIQRLRQRCLQAGVRFDTLRELENGSETTWRAGGHSSPIFFGFGNLNSQQLKKVL
LVIEQQLLYLDQEHGSLY
>Mature_498_residues
MWELELDRVCDTPLQLQIFQYYYQAITRGNYVCGDMLPSIRKLAGKLQVARITVVLAYEKLVIGGYIKSRPGIGYQVVFD
RQVKPVRHIPSYFKGPAPTRLLTAEVPGDLYSQPTSELYCRMSIPDPNAFPWASWRKWNNSPSCLKEQLVTRYHSPHGLL
PLRQEIARYLHLSRSIEIRPENIIITNGVQEGLSLLSQLFVLKRTTSSHIPCHIVTESPCYSGAWHLFNYYGAQVTTLDV
DKQGMCVSHLPERSTQLCYVTPSHQYPLGSQLSLSRRKTLLLWAQRVGAYVIEDDYDAVFSWGQKPLPPLKAMDSQDRVI
YAGTFSKTLGPGIRLGYLVCPDAILPSVQNMKALSNSGSNWLLQQFLAEFMHSQVFYTHLSKLTCEYEMRQTLLRKGLKR
LFPEGQLWGHAAGLHLTLITSMTDDVIQRLRQRCLQAGVRFDTLRELENGSETTWRAGGHSSPIFFGFGNLNSQQLKKVL
LVIEQQLLYLDQEHGSLY

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=381, Percent_Identity=22.5721784776903, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI33469970, Length=381, Percent_Identity=22.5721784776903, Blast_Score=90, Evalue=5e-18,
Organism=Escherichia coli, GI1787710, Length=403, Percent_Identity=26.7990074441687, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790797, Length=395, Percent_Identity=27.3417721518987, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 56746; Mature: 56746

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWELELDRVCDTPLQLQIFQYYYQAITRGNYVCGDMLPSIRKLAGKLQVARITVVLAYEK
CCCCCHHHHCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCEEEEEEEEEEHHH
LVIGGYIKSRPGIGYQVVFDRQVKPVRHIPSYFKGPAPTRLLTAEVPGDLYSQPTSELYC
HHCCCHHCCCCCCCEEEEECCCCCHHHHCHHHHCCCCCCEEEEECCCCHHHCCCCCCEEE
RMSIPDPNAFPWASWRKWNNSPSCLKEQLVTRYHSPHGLLPLRQEIARYLHLSRSIEIRP
EEECCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEECC
ENIIITNGVQEGLSLLSQLFVLKRTTSSHIPCHIVTESPCYSGAWHLFNYYGAQVTTLDV
CCEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHCCCEEEEEEC
DKQGMCVSHLPERSTQLCYVTPSHQYPLGSQLSLSRRKTLLLWAQRVGAYVIEDDYDAVF
CCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCHHHHH
SWGQKPLPPLKAMDSQDRVIYAGTFSKTLGPGIRLGYLVCPDAILPSVQNMKALSNSGSN
HCCCCCCCCHHCCCCCCCEEEEECCHHHCCCCCEEEEEECCHHHCCCHHHHHHHHCCCCH
WLLQQFLAEFMHSQVFYTHLSKLTCEYEMRQTLLRKGLKRLFPEGQLWGHAAGLHLTLIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEH
SMTDDVIQRLRQRCLQAGVRFDTLRELENGSETTWRAGGHSSPIFFGFGNLNSQQLKKVL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCCCCEEEEECCCCHHHHHHHH
LVIEQQLLYLDQEHGSLY
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MWELELDRVCDTPLQLQIFQYYYQAITRGNYVCGDMLPSIRKLAGKLQVARITVVLAYEK
CCCCCHHHHCCCCHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCEEEEEEEEEEHHH
LVIGGYIKSRPGIGYQVVFDRQVKPVRHIPSYFKGPAPTRLLTAEVPGDLYSQPTSELYC
HHCCCHHCCCCCCCEEEEECCCCCHHHHCHHHHCCCCCCEEEEECCCCHHHCCCCCCEEE
RMSIPDPNAFPWASWRKWNNSPSCLKEQLVTRYHSPHGLLPLRQEIARYLHLSRSIEIRP
EEECCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEECC
ENIIITNGVQEGLSLLSQLFVLKRTTSSHIPCHIVTESPCYSGAWHLFNYYGAQVTTLDV
CCEEEECCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHCCCEEEEEEC
DKQGMCVSHLPERSTQLCYVTPSHQYPLGSQLSLSRRKTLLLWAQRVGAYVIEDDYDAVF
CCCCCHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEECCHHHHH
SWGQKPLPPLKAMDSQDRVIYAGTFSKTLGPGIRLGYLVCPDAILPSVQNMKALSNSGSN
HCCCCCCCCHHCCCCCCCEEEEECCHHHCCCCCEEEEEECCHHHCCCHHHHHHHHCCCCH
WLLQQFLAEFMHSQVFYTHLSKLTCEYEMRQTLLRKGLKRLFPEGQLWGHAAGLHLTLIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEH
SMTDDVIQRLRQRCLQAGVRFDTLRELENGSETTWRAGGHSSPIFFGFGNLNSQQLKKVL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEECCCCCCCEEEEECCCCHHHHHHHH
LVIEQQLLYLDQEHGSLY
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]