Click here to switch to the map view.

The map label for this gene is emtA [H]

Identifier: 157372466

GI number: 157372466

Start: 4695776

End: 4696423

Strand: Direct

Name: emtA [H]

Synonym: Spro_4233

Alternate gene names: 157372466

Gene position: 4695776-4696423 (Clockwise)

Preceding gene: 157372465

Following gene: 157372468

Centisome position: 86.18

GC content: 53.55

Gene sequence:

>648_bases
ATGATGCCCGACTTTATCCCAGTAAAAACAATACGGAGCACCATGAACCCCACTCTACGACTCTGGTCACGCGCAGGCAT
TGTCTGCCTGATGCTGATCCTGGCCGGTTGTTCCAGCAAAAAACCGCGTACCAGCTATGATGCTCACGCTTTTGATGACG
CAATTGAAGATGCTGCGGATAAATACGATGTCGATCAAAAGCTGATCGCCGCGATGATTAAGGTGGAATCCGGCTTTAAC
CCGGCTGCAATCAGCCGGTCAAATGCCATAGGGTTAATGCAGCTGAAAGCCGATACCGCAGGTTGCGACGCCTATCGCTA
CAAAGGCAAACGCGGCTGCCCGGACGAAGACGATTTGCTGGATCCGGATACCAATATCGATCTCGGTGCCGCCTATATTG
CCGTATTGCAAAAACAGCAGCTTAAGGGGATCGACGATCCCGTCACGCTTCGTTACGCCACCATCATCGCGTACGTAAAC
GGCACCGGCGCGCTGCTGCGGACCTTCTCCAGCAACCGCCAGCAAGCCATTTCGATGATTAACAATCTGTCGCCGGAAGC
CTTTAACTGGCATGTCCGCAAGTATCATCCCGCCCCGCAGGCACCGCGCCATTTGATGAAAGTAGAAGCGGCCTACGAGC
AACTTTGA

Upstream 100 bases:

>100_bases
AGGCCCAGGCCACGCATATCGGCTTTGGCCAACTGACGCGCGCGCAGCAGGTGACGGGGATAGGCTATCTGTATGTCGAA
CAGGCACTGACGGAGATGCT

Downstream 100 bases:

>100_bases
TTTTCAACGCAAAAAGGAGAACCCTGGGGTTCTCCTTTTCGTTTAAGAGCACTGCCCGACCGTTAGGGTTTACCGCTGCG
GATAGGCTTGCGCGGCGGCT

Product: lytic transglycosylase

Products: NA

Alternate protein names: Peptidoglycan lytic endotransglycosylase [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MMPDFIPVKTIRSTMNPTLRLWSRAGIVCLMLILAGCSSKKPRTSYDAHAFDDAIEDAADKYDVDQKLIAAMIKVESGFN
PAAISRSNAIGLMQLKADTAGCDAYRYKGKRGCPDEDDLLDPDTNIDLGAAYIAVLQKQQLKGIDDPVTLRYATIIAYVN
GTGALLRTFSSNRQQAISMINNLSPEAFNWHVRKYHPAPQAPRHLMKVEAAYEQL

Sequences:

>Translated_215_residues
MMPDFIPVKTIRSTMNPTLRLWSRAGIVCLMLILAGCSSKKPRTSYDAHAFDDAIEDAADKYDVDQKLIAAMIKVESGFN
PAAISRSNAIGLMQLKADTAGCDAYRYKGKRGCPDEDDLLDPDTNIDLGAAYIAVLQKQQLKGIDDPVTLRYATIIAYVN
GTGALLRTFSSNRQQAISMINNLSPEAFNWHVRKYHPAPQAPRHLMKVEAAYEQL
>Mature_215_residues
MMPDFIPVKTIRSTMNPTLRLWSRAGIVCLMLILAGCSSKKPRTSYDAHAFDDAIEDAADKYDVDQKLIAAMIKVESGFN
PAAISRSNAIGLMQLKADTAGCDAYRYKGKRGCPDEDDLLDPDTNIDLGAAYIAVLQKQQLKGIDDPVTLRYATIIAYVN
GTGALLRTFSSNRQQAISMINNLSPEAFNWHVRKYHPAPQAPRHLMKVEAAYEQL

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87081855, Length=195, Percent_Identity=47.6923076923077, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI87082191, Length=164, Percent_Identity=44.5121951219512, Blast_Score=150, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 23794; Mature: 23794

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPDFIPVKTIRSTMNPTLRLWSRAGIVCLMLILAGCSSKKPRTSYDAHAFDDAIEDAAD
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
KYDVDQKLIAAMIKVESGFNPAAISRSNAIGLMQLKADTAGCDAYRYKGKRGCPDEDDLL
HCCHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEECCCCCCHHHHCCCCCCCCCCCCCC
DPDTNIDLGAAYIAVLQKQQLKGIDDPVTLRYATIIAYVNGTGALLRTFSSNRQQAISMI
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHEEEEEEEEECCCHHHHHHHHCCHHHHHHHH
NNLSPEAFNWHVRKYHPAPQAPRHLMKVEAAYEQL
HCCCCCHHEEEEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMPDFIPVKTIRSTMNPTLRLWSRAGIVCLMLILAGCSSKKPRTSYDAHAFDDAIEDAAD
CCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
KYDVDQKLIAAMIKVESGFNPAAISRSNAIGLMQLKADTAGCDAYRYKGKRGCPDEDDLL
HCCHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEECCCCCCHHHHCCCCCCCCCCCCCC
DPDTNIDLGAAYIAVLQKQQLKGIDDPVTLRYATIIAYVNGTGALLRTFSSNRQQAISMI
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHEEEEEEEEECCCHHHHHHHHCCHHHHHHHH
NNLSPEAFNWHVRKYHPAPQAPRHLMKVEAAYEQL
HCCCCCHHEEEEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA