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The map label for this gene is speB

Identifier: 157372206

GI number: 157372206

Start: 4400159

End: 4401079

Strand: Reverse

Name: speB

Synonym: Spro_3972

Alternate gene names: 157372206

Gene position: 4401079-4400159 (Counterclockwise)

Preceding gene: 157372207

Following gene: 157372205

Centisome position: 80.77

GC content: 57.65

Gene sequence:

>921_bases
ATGAGTACCTTAGGCCATAAGTCCGATAATTCTTTAGTGTCCAACGCCTTTGGTTTCCTGCGCTTTCCGCTGAACTTTAT
GCCTTACGACAGCGATGCAGAGTGGGTCATCACCGGCATTCCATTTGACATGGCAACCTCCGGCCGCGCCGGTGGCCGTC
ATGGCCCTGCGGCGATCCGTCAGGTTTCTACTAACCTGGCCTGGGAAGGCAACCGCTGGCCGTGGAACTTTGACCTGCGC
GATCGTGTGAACGTCGTCGATTGTGGCGACATCGTGTTCAACTTTGGTGATGCTCAGAGCATGAGCGACAACCTGCAGGC
GCACGCGGAAAAACTGCTGGCGGCCGGTAAACGTATGCTCTCATTCGGCGGCGACCACTTCGTCACGTTGCCACTGTTGC
GCGCGCACGCCAAACATTTCGGCAAAATGGCGCTGGTGCATTTCGATGCCCATACCGACACCTACGCCAACGGCAGCCAA
TACGACCACGGCACCATGTTCTTCCATGCGCCGAACGAAGGCCTGATCGATCCAACACACTCGGTGCAGATCGGTATCCG
TACCGAATACGATCACGACAACGGCTTTACCGTATTGGATGCTGCGCAGGTTAACGATCGCAGCGCGGACGACCTGTTGG
CCCAGATCAAACAGATCGTCGGCGATATGCCGGTCTACCTGACCTTCGATATCGACTGTCTGGATCCGGCGTTCGCACCG
GGCACCGGCACGCCGGTGATCGGCGGCCTGACCTCCGATCGCGCGCTGAAACTGGTTCGCGGCATGCAATCACTGAACAT
CGTGGGTATGGACGTAGTGGAAGTGGCACCGGCCTACGATCAGTCCGAGATCACCGCGCTGGCTGCGGCGACCCTGGGCC
TGGAAATGCTGTATCTGCAGGCAGCAAAAAAAACCAAATAA

Upstream 100 bases:

>100_bases
GATCCCTTTCTCGTCGGGCTAACGACGCGAGAGGGATTTTTTTTTGCCAGCGCCTGTGTGATTTTTCAACAGGTGAAACG
TTGAAATATGAGGGTTTACT

Downstream 100 bases:

>100_bases
GTTCCTAATGGTATTAACAGGCGGTTATGGGCTGTAAGCACGGTACCATAAAGAAATACACATAACCGGTATCTATATAC
CCTATGGATTTCAAGTCACA

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSTLGHKSDNSLVSNAFGFLRFPLNFMPYDSDAEWVITGIPFDMATSGRAGGRHGPAAIRQVSTNLAWEGNRWPWNFDLR
DRVNVVDCGDIVFNFGDAQSMSDNLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGSQ
YDHGTMFFHAPNEGLIDPTHSVQIGIRTEYDHDNGFTVLDAAQVNDRSADDLLAQIKQIVGDMPVYLTFDIDCLDPAFAP
GTGTPVIGGLTSDRALKLVRGMQSLNIVGMDVVEVAPAYDQSEITALAAATLGLEMLYLQAAKKTK

Sequences:

>Translated_306_residues
MSTLGHKSDNSLVSNAFGFLRFPLNFMPYDSDAEWVITGIPFDMATSGRAGGRHGPAAIRQVSTNLAWEGNRWPWNFDLR
DRVNVVDCGDIVFNFGDAQSMSDNLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGSQ
YDHGTMFFHAPNEGLIDPTHSVQIGIRTEYDHDNGFTVLDAAQVNDRSADDLLAQIKQIVGDMPVYLTFDIDCLDPAFAP
GTGTPVIGGLTSDRALKLVRGMQSLNIVGMDVVEVAPAYDQSEITALAAATLGLEMLYLQAAKKTK
>Mature_305_residues
STLGHKSDNSLVSNAFGFLRFPLNFMPYDSDAEWVITGIPFDMATSGRAGGRHGPAAIRQVSTNLAWEGNRWPWNFDLRD
RVNVVDCGDIVFNFGDAQSMSDNLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGSQY
DHGTMFFHAPNEGLIDPTHSVQIGIRTEYDHDNGFTVLDAAQVNDRSADDLLAQIKQIVGDMPVYLTFDIDCLDPAFAPG
TGTPVIGGLTSDRALKLVRGMQSLNIVGMDVVEVAPAYDQSEITALAAATLGLEMLYLQAAKKTK

Specific function: Catalyzes the formation of putrescine from agmatine

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily

Homologues:

Organism=Homo sapiens, GI37537722, Length=290, Percent_Identity=42.7586206896552, Blast_Score=211, Evalue=5e-55,
Organism=Homo sapiens, GI4502215, Length=313, Percent_Identity=26.1980830670927, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1789306, Length=304, Percent_Identity=87.1710526315789, Blast_Score=547, Evalue=1e-157,
Organism=Saccharomyces cerevisiae, GI6325146, Length=197, Percent_Identity=26.9035532994924, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEB_SERP5 (A8GIX7)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480195.1
- ProteinModelPortal:   A8GIX7
- SMR:   A8GIX7
- STRING:   A8GIX7
- GeneID:   5603149
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_3972
- eggNOG:   COG0010
- HOGENOM:   HBG391953
- OMA:   TNLAWEG
- ProtClustDB:   PRK02190
- BioCyc:   SPRO399741:SPRO_3972-MONOMER
- HAMAP:   MF_01418
- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855
- Gene3D:   G3DSA:3.40.800.10
- PANTHER:   PTHR11358
- TIGRFAMs:   TIGR01230

Pfam domain/function: PF00491 Arginase

EC number: =3.5.3.11

Molecular weight: Translated: 33374; Mature: 33243

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS01053 ARGINASE_1; PS51409 ARGINASE_2; PS00147 ARGINASE_1 ; PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLGHKSDNSLVSNAFGFLRFPLNFMPYDSDAEWVITGIPFDMATSGRAGGRHGPAAIR
CCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
QVSTNLAWEGNRWPWNFDLRDRVNVVDCGDIVFNFGDAQSMSDNLQAHAEKLLAAGKRML
HHHHCCEECCCCCCCCCCHHCCCCEEEECHHEEECCCCHHHHHHHHHHHHHHHHHHHHHH
SFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGSQYDHGTMFFHAPNEGLIDPTH
HCCCCCEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
SVQIGIRTEYDHDNGFTVLDAAQVNDRSADDLLAQIKQIVGDMPVYLTFDIDCLDPAFAP
EEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCC
GTGTPVIGGLTSDRALKLVRGMQSLNIVGMDVVEVAPAYDQSEITALAAATLGLEMLYLQ
CCCCCEECCCCCHHHHHHHHHHHHCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AAKKTK
HHHCCC
>Mature Secondary Structure 
STLGHKSDNSLVSNAFGFLRFPLNFMPYDSDAEWVITGIPFDMATSGRAGGRHGPAAIR
CCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
QVSTNLAWEGNRWPWNFDLRDRVNVVDCGDIVFNFGDAQSMSDNLQAHAEKLLAAGKRML
HHHHCCEECCCCCCCCCCHHCCCCEEEECHHEEECCCCHHHHHHHHHHHHHHHHHHHHHH
SFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGSQYDHGTMFFHAPNEGLIDPTH
HCCCCCEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
SVQIGIRTEYDHDNGFTVLDAAQVNDRSADDLLAQIKQIVGDMPVYLTFDIDCLDPAFAP
EEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCC
GTGTPVIGGLTSDRALKLVRGMQSLNIVGMDVVEVAPAYDQSEITALAAATLGLEMLYLQ
CCCCCEECCCCCHHHHHHHHHHHHCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AAKKTK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA