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The map label for this gene is sgbH [H]

Identifier: 157372171

GI number: 157372171

Start: 4361944

End: 4362600

Strand: Direct

Name: sgbH [H]

Synonym: Spro_3937

Alternate gene names: 157372171

Gene position: 4361944-4362600 (Clockwise)

Preceding gene: 157372170

Following gene: 157372172

Centisome position: 80.05

GC content: 63.93

Gene sequence:

>657_bases
ATGAGCAACAAACCGCGTCTGCAACTGGCGCTCGATCACACCCGGCTGGACGCCGCCCTGCAAACGGCAGAACGCCTGCA
GCCGCACGTCGACATTATCGAGGCCGGCACCATTTTATGCATCAGCGCCGGTATCCAGGCGGTGAGCGCGCTGCGTGAAC
GCTGCCCACAACATACGCTGGTGGCCGACCTGAAAGTGGCCGATGCCGGTGGCACGCTGGCGCAGCAGGCCTTCAGCCAC
GGTGCCAACTGGATGACGGTGATCTGCGCCGCGCCGTTAGCCACCATGGCCAGCGCGCTGGAGGTGGCGCAACAGCACCA
GGGCGAGATCCAGATTGAGCTGTTCGGCCGCTGGACGCTGGACGATGCCCGGCAGTGGCGCGAGCTTGGCATCCGCCAGG
CGATCTACCACCGTGGCCGCGACGCCCAGGCCAGCGGACAAACCTGGGGCCGACAGGATTTGGATCTGATGAAAGCGTTG
TCGGATCTGGGCATTGAGCTGTCGGTCACTGGCGGCATCACCCCGACCGATTTACCGCTGTTTAAGGACATCGCCGTTAC
CGCTTTTATCGTCGGCCGGGCGTTGGCAGAAGCTGCCGATCCGCTGACCGCCGCCGGTCAGTTCCGCACCGCCATTGATG
ACATCTGGAGAAGTTGA

Upstream 100 bases:

>100_bases
GGGTGCTGCCGGACGCAGCAGCAGCAGAGGCTTACGGTAAAAAATATCAATGTTATCAGGCGCTGGTAGCCACGCTGCAA
TCCATCCAGAAGGAGGCCCT

Downstream 100 bases:

>100_bases
TATGCGCCAGCACCCATTGGGAATTTATGAAAAAGCCCTGCCGAAACACCTGACCTGGCCCGAGCGTCTGGCGCTGGCCA
AGGCCTGCGGTTTTGATTTT

Product: 3-keto-L-gulonate-6-phosphate decarboxylase

Products: NA

Alternate protein names: KGPDC; 3-dehydro-L-gulonate-6-phosphate decarboxylase [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MSNKPRLQLALDHTRLDAALQTAERLQPHVDIIEAGTILCISAGIQAVSALRERCPQHTLVADLKVADAGGTLAQQAFSH
GANWMTVICAAPLATMASALEVAQQHQGEIQIELFGRWTLDDARQWRELGIRQAIYHRGRDAQASGQTWGRQDLDLMKAL
SDLGIELSVTGGITPTDLPLFKDIAVTAFIVGRALAEAADPLTAAGQFRTAIDDIWRS

Sequences:

>Translated_218_residues
MSNKPRLQLALDHTRLDAALQTAERLQPHVDIIEAGTILCISAGIQAVSALRERCPQHTLVADLKVADAGGTLAQQAFSH
GANWMTVICAAPLATMASALEVAQQHQGEIQIELFGRWTLDDARQWRELGIRQAIYHRGRDAQASGQTWGRQDLDLMKAL
SDLGIELSVTGGITPTDLPLFKDIAVTAFIVGRALAEAADPLTAAGQFRTAIDDIWRS
>Mature_217_residues
SNKPRLQLALDHTRLDAALQTAERLQPHVDIIEAGTILCISAGIQAVSALRERCPQHTLVADLKVADAGGTLAQQAFSHG
ANWMTVICAAPLATMASALEVAQQHQGEIQIELFGRWTLDDARQWRELGIRQAIYHRGRDAQASGQTWGRQDLDLMKALS
DLGIELSVTGGITPTDLPLFKDIAVTAFIVGRALAEAADPLTAAGQFRTAIDDIWRS

Specific function: Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. May be involved in the utilization of 2,3- diketo-L-gulonate [H]

COG id: COG0269

COG function: function code G; 3-hexulose-6-phosphate synthase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. KGPDC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790006, Length=214, Percent_Identity=67.2897196261682, Blast_Score=289, Evalue=1e-79,
Organism=Escherichia coli, GI1790640, Length=212, Percent_Identity=47.6415094339623, Blast_Score=215, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001754
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00215 OMPdecase [H]

EC number: =4.1.1.85 [H]

Molecular weight: Translated: 23612; Mature: 23481

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKPRLQLALDHTRLDAALQTAERLQPHVDIIEAGTILCISAGIQAVSALRERCPQHTL
CCCCCCEEEEECHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHH
VADLKVADAGGTLAQQAFSHGANWMTVICAAPLATMASALEVAQQHQGEIQIELFGRWTL
HHHEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCH
DDARQWRELGIRQAIYHRGRDAQASGQTWGRQDLDLMKALSDLGIELSVTGGITPTDLPL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCHH
FKDIAVTAFIVGRALAEAADPLTAAGQFRTAIDDIWRS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNKPRLQLALDHTRLDAALQTAERLQPHVDIIEAGTILCISAGIQAVSALRERCPQHTL
CCCCCEEEEECHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHH
VADLKVADAGGTLAQQAFSHGANWMTVICAAPLATMASALEVAQQHQGEIQIELFGRWTL
HHHEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCH
DDARQWRELGIRQAIYHRGRDAQASGQTWGRQDLDLMKALSDLGIELSVTGGITPTDLPL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCHH
FKDIAVTAFIVGRALAEAADPLTAAGQFRTAIDDIWRS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 9274005; 11741871 [H]