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The map label for this gene is mdtP [H]

Identifier: 157371977

GI number: 157371977

Start: 4130626

End: 4132077

Strand: Direct

Name: mdtP [H]

Synonym: Spro_3742

Alternate gene names: 157371977

Gene position: 4130626-4132077 (Clockwise)

Preceding gene: 157371976

Following gene: 157371978

Centisome position: 75.81

GC content: 59.44

Gene sequence:

>1452_bases
ATGCGATCCCCGTTTAACTGGAGATTCACCCCGCTGTTCGCCGTATTGCTGCTGGCCGGGTGCGCTTCTACCGACAATAT
TGCCCCGCAGTCCACCTTGATGGACCCGCAGAGCCTGCAATTGTCACAGCCGAAAGTCAGCTCGCTGAACGTTAGCCCAC
AGTGGTGGCGCTCGCTTAACGATCCGCAGCTCGACAGTCTGATGACCCAGACGCTGCAAAGCTCACCGACGCTGAGACAA
GCCGCCGGGCGCGTGCGCGAAGCGCAAAGTGTGATGGGTGAAGCCAGTGCAGCCAACGGCCCGAATCTGGATCTGAACGC
CAGCAGCAACCGCCAGAAAGTCCCGCAAAACGTCAACATGGGATTGGGCTATCCACATAAGCCGATCTACGAGAGCTCCA
ACTCGCTGGGGCTGAATCTGGCCTATGAATTTGACTGGTGGGGTAAATACCGCAATCAGGTTAACGCCGCCAAGGCGCAG
GTCGATGCGGCCCGCGCCGAGCAGGAACAGGCTGCGCTGACGCTAACCAGCTCGGTGGCCTCCGCCTATTTCCAGCTGCA
GAGCAATTTCGCGCTGGAAAAACTGCTGCAACAGGAAGTCGACAACAACCAACGCCTGACGGATTTGCGCCAACAACAAT
ATAAAGCCGGCATCACCGGTGTTGATGTTCCGCAACAAAGCCAGGCGCAGGCCGACGGTGCCAAGCAGCAGATCCTGCAA
CTGCAGTCGCAGATTGAACAGCTAAGACACCAGTTGGCCGCGCTGGCCGGCCAGGGCCCGAGCGCGATGCAGCATCTGCG
TCCGGTGGCTCTGCCCGCCAGTAATCTGATGGCGCCAAAAGGTGAACTGACCGCCGATCTGCTGGGCAAACGCCCGGATA
TCGCCGCGCAGCGTCAGTTGGTCGAGTCTTACAACCAACGCGTCAGCGCCGCCCGCAAGGAATTTTACCCCAGCCTGACC
ATTTCAGCCTTTGCCGGCCTGACTACCACCAACACCAGTGGGACCAGCCCGAATCTGTTTGAAGCGGCCAGCCAGGCCTG
GAACGTGATGCCGGCGATTTCATTGCCGATCTTCCACGCCGGTGCGCTGCGCAGCAAACTGGGTGAGGAGTCCGCGCTGT
ATGACCAGGCGGTGGAGTCCTATAACCAAACCATCCTGAATGCCGTGCAGGAAACCGCTGATGCCATCACCGTCCAACAA
AGCACTGCGCAACAGCAGCTGCAGGCGGCATCTGCGTCCCAATCGATGCAACAGGTGTACCGCGTCGCTAACGCTCGATA
CCAGGCAGGGATTATCGGGCGCGACCAGTTGTTAACCAGCCAGACGCAGCTCTTGCAGCAGCAACAGGCGGAACTGAATG
CCAACAGCAACTTGCTGCAGGCGAAGATAGGACTGATCCGTGCGCTGGGCGGTGGCTATCAGGCCCCGGTCGCTGCGGAT
TCAAAAGCATAA

Upstream 100 bases:

>100_bases
GCAACAGCTTGAACAGCTGACACGCAAGCTGTTAACGCGTCTGGACCAGATGGAAGTTTCAGGACAGTTATCCCAATAAT
TTCTGTTCAGGTAACCTACT

Downstream 100 bases:

>100_bases
TAAAATAGAGAGCTTGGAGAACACCATGAGCGCAAGCGCGGAGACTCAGACCCCGCCACAACCTGTCGGCAAAAAGAAGC
AGCGCAAGTTTTGGCTGCTG

Product: RND efflux system outer membrane lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MRSPFNWRFTPLFAVLLLAGCASTDNIAPQSTLMDPQSLQLSQPKVSSLNVSPQWWRSLNDPQLDSLMTQTLQSSPTLRQ
AAGRVREAQSVMGEASAANGPNLDLNASSNRQKVPQNVNMGLGYPHKPIYESSNSLGLNLAYEFDWWGKYRNQVNAAKAQ
VDAARAEQEQAALTLTSSVASAYFQLQSNFALEKLLQQEVDNNQRLTDLRQQQYKAGITGVDVPQQSQAQADGAKQQILQ
LQSQIEQLRHQLAALAGQGPSAMQHLRPVALPASNLMAPKGELTADLLGKRPDIAAQRQLVESYNQRVSAARKEFYPSLT
ISAFAGLTTTNTSGTSPNLFEAASQAWNVMPAISLPIFHAGALRSKLGEESALYDQAVESYNQTILNAVQETADAITVQQ
STAQQQLQAASASQSMQQVYRVANARYQAGIIGRDQLLTSQTQLLQQQQAELNANSNLLQAKIGLIRALGGGYQAPVAAD
SKA

Sequences:

>Translated_483_residues
MRSPFNWRFTPLFAVLLLAGCASTDNIAPQSTLMDPQSLQLSQPKVSSLNVSPQWWRSLNDPQLDSLMTQTLQSSPTLRQ
AAGRVREAQSVMGEASAANGPNLDLNASSNRQKVPQNVNMGLGYPHKPIYESSNSLGLNLAYEFDWWGKYRNQVNAAKAQ
VDAARAEQEQAALTLTSSVASAYFQLQSNFALEKLLQQEVDNNQRLTDLRQQQYKAGITGVDVPQQSQAQADGAKQQILQ
LQSQIEQLRHQLAALAGQGPSAMQHLRPVALPASNLMAPKGELTADLLGKRPDIAAQRQLVESYNQRVSAARKEFYPSLT
ISAFAGLTTTNTSGTSPNLFEAASQAWNVMPAISLPIFHAGALRSKLGEESALYDQAVESYNQTILNAVQETADAITVQQ
STAQQQLQAASASQSMQQVYRVANARYQAGIIGRDQLLTSQTQLLQQQQAELNANSNLLQAKIGLIRALGGGYQAPVAAD
SKA
>Mature_483_residues
MRSPFNWRFTPLFAVLLLAGCASTDNIAPQSTLMDPQSLQLSQPKVSSLNVSPQWWRSLNDPQLDSLMTQTLQSSPTLRQ
AAGRVREAQSVMGEASAANGPNLDLNASSNRQKVPQNVNMGLGYPHKPIYESSNSLGLNLAYEFDWWGKYRNQVNAAKAQ
VDAARAEQEQAALTLTSSVASAYFQLQSNFALEKLLQQEVDNNQRLTDLRQQQYKAGITGVDVPQQSQAQADGAKQQILQ
LQSQIEQLRHQLAALAGQGPSAMQHLRPVALPASNLMAPKGELTADLLGKRPDIAAQRQLVESYNQRVSAARKEFYPSLT
ISAFAGLTTTNTSGTSPNLFEAASQAWNVMPAISLPIFHAGALRSKLGEESALYDQAVESYNQTILNAVQETADAITVQQ
STAQQQLQAASASQSMQQVYRVANARYQAGIIGRDQLLTSQTQLLQQQQAELNANSNLLQAKIGLIRALGGGYQAPVAAD
SKA

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI2367348, Length=478, Percent_Identity=31.1715481171548, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1786785, Length=495, Percent_Identity=27.2727272727273, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 52433; Mature: 52433

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSPFNWRFTPLFAVLLLAGCASTDNIAPQSTLMDPQSLQLSQPKVSSLNVSPQWWRSLN
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHCCCCCCCCCCCCCCHHHHHCCC
DPQLDSLMTQTLQSSPTLRQAAGRVREAQSVMGEASAANGPNLDLNASSNRQKVPQNVNM
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCC
GLGYPHKPIYESSNSLGLNLAYEFDWWGKYRNQVNAAKAQVDAARAEQEQAALTLTSSVA
CCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAYFQLQSNFALEKLLQQEVDNNQRLTDLRQQQYKAGITGVDVPQQSQAQADGAKQQILQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
LQSQIEQLRHQLAALAGQGPSAMQHLRPVALPASNLMAPKGELTADLLGKRPDIAAQRQL
HHHHHHHHHHHHHHHHCCCHHHHHHCCCHHCCHHHCCCCCCCHHHHHHCCCCCHHHHHHH
VESYNQRVSAARKEFYPSLTISAFAGLTTTNTSGTSPNLFEAASQAWNVMPAISLPIFHA
HHHHHHHHHHHHHHHCCCHHHHHHHCCEECCCCCCCCHHHHHHHHHHCCCHHHHCHHHHH
GALRSKLGEESALYDQAVESYNQTILNAVQETADAITVQQSTAQQQLQAASASQSMQQVY
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVANARYQAGIIGRDQLLTSQTQLLQQQQAELNANSNLLQAKIGLIRALGGGYQAPVAAD
HHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCC
SKA
CCC
>Mature Secondary Structure
MRSPFNWRFTPLFAVLLLAGCASTDNIAPQSTLMDPQSLQLSQPKVSSLNVSPQWWRSLN
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHCCCCCCCCCCCCCCHHHHHCCC
DPQLDSLMTQTLQSSPTLRQAAGRVREAQSVMGEASAANGPNLDLNASSNRQKVPQNVNM
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCC
GLGYPHKPIYESSNSLGLNLAYEFDWWGKYRNQVNAAKAQVDAARAEQEQAALTLTSSVA
CCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAYFQLQSNFALEKLLQQEVDNNQRLTDLRQQQYKAGITGVDVPQQSQAQADGAKQQILQ
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
LQSQIEQLRHQLAALAGQGPSAMQHLRPVALPASNLMAPKGELTADLLGKRPDIAAQRQL
HHHHHHHHHHHHHHHHCCCHHHHHHCCCHHCCHHHCCCCCCCHHHHHHCCCCCHHHHHHH
VESYNQRVSAARKEFYPSLTISAFAGLTTTNTSGTSPNLFEAASQAWNVMPAISLPIFHA
HHHHHHHHHHHHHHHCCCHHHHHHHCCEECCCCCCCCHHHHHHHHHHCCCHHHHCHHHHH
GALRSKLGEESALYDQAVESYNQTILNAVQETADAITVQQSTAQQQLQAASASQSMQQVY
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RVANARYQAGIIGRDQLLTSQTQLLQQQQAELNANSNLLQAKIGLIRALGGGYQAPVAAD
HHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCC
SKA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]