Click here to switch to the map view.

The map label for this gene is era [H]

Identifier: 157371903

GI number: 157371903

Start: 4060494

End: 4061402

Strand: Reverse

Name: era [H]

Synonym: Spro_3668

Alternate gene names: 157371903

Gene position: 4061402-4060494 (Counterclockwise)

Preceding gene: 157371904

Following gene: 157371902

Centisome position: 74.54

GC content: 53.36

Gene sequence:

>909_bases
ATGAGCGAAGAGAAACAATACTGTGGTTTTATTGCGATAGTCGGTCGCCCCAACGTGGGCAAGTCCACGTTGCTGAACCA
ACTGCTGGGGCAAAAAGTCTCCATCACCTCGCGTAAACCACAGACGACCCGTCACCGTATTATGGGTATCGACACTGATG
GCGCCTATCAGGCCATCTACGTCGACACCCCGGGTCTGCACATCGAAGAAAAACGCGCCATCAACCGTTTGATGAACCGC
GCGGCCAGCAGCTCAATCGGCGACGTCGAGCTGGTGATCTTCGTTGTGGAAGGGACCAACTGGACCGCCGACGATGAAAT
GGTGGTCAACAAGCTGCGTAGCCTGAAATGCCCGGTGCTGCTGGCGATCAACAAGGTCGACAACGTTACCGACAAATCCA
AGCTGTTGCCGCACATTGCGTTCCTCAGCCAGCAGATGAACTTCCTCGACGTAGTGCCGATTTCTGCCGAAAAAGGTATG
AACGTGGATACCATCGCTGCAATCGCACGCAAGGTATTGCCGGAAGCGGAACACCACTTCCCGGACGATTACATCACCGA
TCGTTCCCAGCGCTTTATGGCTTCGGAAATTATCCGTGAAAAGCTGATGCGTTTCCTGGGTGAAGAACTGCCTTACTCGG
TGACGGTTGAGATCGAACAATTTGTGCCGAATGAACGTGGCGGTTACAACGTTCACGGGCTGATCCTGGTTGAGCGCGAA
GGCCAAAAGAAAATGGTCATCGGCAACAAAGGCGCCAAGATCAAAACCATCGGTATCGAAGCCCGCCAGGATATGGAACA
GATGTTTGAAACCAAAGTGCATCTGGAACTGTGGGTGAAAGTGAAATCGGGCTGGGCGGACGACGAACGTGCGTTGCGTA
GCCTGGGCTATACCGACGACCTGAAATAA

Upstream 100 bases:

>100_bases
AGGTGAGTGGTTTGAGCGAACCCGTCGTGGGAACCGGCTCAAGCCGCCGTAAAGCCGAACAAGCGGCAGCGGAACAAGCG
TTAATAAAGCTGGAGCTTGA

Downstream 100 bases:

>100_bases
ACTATCCAATGGACGGCTGGGAACGCGCTTTCGTCCTGCATGGACGACCGTACAGTGAAACCAGCCTGATGCTGGATATG
TTTACCGAAGGTCATGGGCG

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSEEKQYCGFIAIVGRPNVGKSTLLNQLLGQKVSITSRKPQTTRHRIMGIDTDGAYQAIYVDTPGLHIEEKRAINRLMNR
AASSSIGDVELVIFVVEGTNWTADDEMVVNKLRSLKCPVLLAINKVDNVTDKSKLLPHIAFLSQQMNFLDVVPISAEKGM
NVDTIAAIARKVLPEAEHHFPDDYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIEQFVPNERGGYNVHGLILVERE
GQKKMVIGNKGAKIKTIGIEARQDMEQMFETKVHLELWVKVKSGWADDERALRSLGYTDDLK

Sequences:

>Translated_302_residues
MSEEKQYCGFIAIVGRPNVGKSTLLNQLLGQKVSITSRKPQTTRHRIMGIDTDGAYQAIYVDTPGLHIEEKRAINRLMNR
AASSSIGDVELVIFVVEGTNWTADDEMVVNKLRSLKCPVLLAINKVDNVTDKSKLLPHIAFLSQQMNFLDVVPISAEKGM
NVDTIAAIARKVLPEAEHHFPDDYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIEQFVPNERGGYNVHGLILVERE
GQKKMVIGNKGAKIKTIGIEARQDMEQMFETKVHLELWVKVKSGWADDERALRSLGYTDDLK
>Mature_301_residues
SEEKQYCGFIAIVGRPNVGKSTLLNQLLGQKVSITSRKPQTTRHRIMGIDTDGAYQAIYVDTPGLHIEEKRAINRLMNRA
ASSSIGDVELVIFVVEGTNWTADDEMVVNKLRSLKCPVLLAINKVDNVTDKSKLLPHIAFLSQQMNFLDVVPISAEKGMN
VDTIAAIARKVLPEAEHHFPDDYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIEQFVPNERGGYNVHGLILVEREG
QKKMVIGNKGAKIKTIGIEARQDMEQMFETKVHLELWVKVKSGWADDERALRSLGYTDDLK

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=321, Percent_Identity=28.3489096573209, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI1788919, Length=301, Percent_Identity=84.7176079734219, Blast_Score=536, Evalue=1e-154,
Organism=Escherichia coli, GI87082120, Length=181, Percent_Identity=28.1767955801105, Blast_Score=64, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646434, Length=311, Percent_Identity=25.7234726688103, Blast_Score=91, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34084; Mature: 33953

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEKQYCGFIAIVGRPNVGKSTLLNQLLGQKVSITSRKPQTTRHRIMGIDTDGAYQAIY
CCCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEEECCCCCCCCHHEEEEECCCCCEEEEE
VDTPGLHIEEKRAINRLMNRAASSSIGDVELVIFVVEGTNWTADDEMVVNKLRSLKCPVL
EECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCEE
LAINKVDNVTDKSKLLPHIAFLSQQMNFLDVVPISAEKGMNVDTIAAIARKVLPEAEHHF
EEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHCC
PDDYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIEQFVPNERGGYNVHGLILVERE
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCCCCEEEEEEEEEEEC
GQKKMVIGNKGAKIKTIGIEARQDMEQMFETKVHLELWVKVKSGWADDERALRSLGYTDD
CCEEEEECCCCCEEEEEECHHHHHHHHHHHHHEEEEEEEEEECCCCCHHHHHHHCCCCCC
LK
CC
>Mature Secondary Structure 
SEEKQYCGFIAIVGRPNVGKSTLLNQLLGQKVSITSRKPQTTRHRIMGIDTDGAYQAIY
CCCCCCCEEEEEECCCCCCHHHHHHHHHCCEEEECCCCCCCCHHEEEEECCCCCEEEEE
VDTPGLHIEEKRAINRLMNRAASSSIGDVELVIFVVEGTNWTADDEMVVNKLRSLKCPVL
EECCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCEE
LAINKVDNVTDKSKLLPHIAFLSQQMNFLDVVPISAEKGMNVDTIAAIARKVLPEAEHHF
EEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCHHHCC
PDDYITDRSQRFMASEIIREKLMRFLGEELPYSVTVEIEQFVPNERGGYNVHGLILVERE
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHCCCCCCCEEEEEEEEEEEC
GQKKMVIGNKGAKIKTIGIEARQDMEQMFETKVHLELWVKVKSGWADDERALRSLGYTDD
CCEEEEECCCCCEEEEEECHHHHHHHHHHHHHEEEEEEEEEECCCCCHHHHHHHCCCCCC
LK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA