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The map label for this gene is sgaR [H]

Identifier: 157371824

GI number: 157371824

Start: 3965112

End: 3965744

Strand: Direct

Name: sgaR [H]

Synonym: Spro_3589

Alternate gene names: 157371824

Gene position: 3965112-3965744 (Clockwise)

Preceding gene: 157371821

Following gene: 157371825

Centisome position: 72.77

GC content: 44.71

Gene sequence:

>633_bases
TTGGGACAGGAGTATGCACTGGTCGTTGATGACCATCCTTTGGTGGCAAGTGGCATCGCCAATTTTCTTAATACGCATTG
TCGATTTAAACATGTCCACATGGCGACCAACGAAGATCATTGCTATCGCCACATTATGCTAAATGGCCCTCCTCGTTTAA
TGGTTATAGATTTTTGGCTATCCAATGGCACGGCGCTTAAATTCCTCAAAGAGATGAATGAACGTTATTCACAAATTCGC
TTATTGGTGGTCAGTGGCGACGACAACAATGAAATATGGCAAAAGGTTAGAGAGGCCGGCGGCCATGGTTTCGTGCTTAA
AAATGAATCTCCTGAATTATTCGCCAAAGCCGTAGCCACACTCACAGACAATCGACTATGGTTTCCTCAGGATAATGCGA
CGGGTGTAACGCCCGTCCAAAACCATTTGCAACATTTAAATCTAACGCCGCGACAGGTTGAAGTGCTTGCCATGATGTTG
CGTGGTTTTCCTAATAAAAGAATAGCCTCACAACTTTCAATTTCAGAACCCACAGTTAAAGAGCACATCAGTAATATTCT
GAAAAAGATAGGTGTGAATAGTCGGGTAGAGGCGATCACCCTGCTCCACGGCAGATCGGGGCCATTACAATGA

Upstream 100 bases:

>100_bases
TATTTCTCTTTCCTAAACGAAAAAACCCTCCTAAAGTAGGGAGGGTGGATAATAAGAGATTACCGGAACCATCCGATACG
TTTATACGAAGGAGCTAGCT

Downstream 100 bases:

>100_bases
AGTTACTTCAATCTTTACAAGATGATGGTATTTCTCCCCGTGCGCAAATCCGTCTGCTGGACAATACATTTATACGCCTG
GTATTTAGCTTCAGCGCAGT

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MGQEYALVVDDHPLVASGIANFLNTHCRFKHVHMATNEDHCYRHIMLNGPPRLMVIDFWLSNGTALKFLKEMNERYSQIR
LLVVSGDDNNEIWQKVREAGGHGFVLKNESPELFAKAVATLTDNRLWFPQDNATGVTPVQNHLQHLNLTPRQVEVLAMML
RGFPNKRIASQLSISEPTVKEHISNILKKIGVNSRVEAITLLHGRSGPLQ

Sequences:

>Translated_210_residues
MGQEYALVVDDHPLVASGIANFLNTHCRFKHVHMATNEDHCYRHIMLNGPPRLMVIDFWLSNGTALKFLKEMNERYSQIR
LLVVSGDDNNEIWQKVREAGGHGFVLKNESPELFAKAVATLTDNRLWFPQDNATGVTPVQNHLQHLNLTPRQVEVLAMML
RGFPNKRIASQLSISEPTVKEHISNILKKIGVNSRVEAITLLHGRSGPLQ
>Mature_209_residues
GQEYALVVDDHPLVASGIANFLNTHCRFKHVHMATNEDHCYRHIMLNGPPRLMVIDFWLSNGTALKFLKEMNERYSQIRL
LVVSGDDNNEIWQKVREAGGHGFVLKNESPELFAKAVATLTDNRLWFPQDNATGVTPVQNHLQHLNLTPRQVEVLAMMLR
GFPNKRIASQLSISEPTVKEHISNILKKIGVNSRVEAITLLHGRSGPLQ

Specific function: Not known. Could act on the sgaA gene expression [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=218, Percent_Identity=28.4403669724771, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786747, Length=207, Percent_Identity=26.5700483091787, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1787473, Length=207, Percent_Identity=28.0193236714976, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788712, Length=198, Percent_Identity=24.7474747474747, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1789937, Length=180, Percent_Identity=25.5555555555556, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23734; Mature: 23602

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQEYALVVDDHPLVASGIANFLNTHCRFKHVHMATNEDHCYRHIMLNGPPRLMVIDFWL
CCCCEEEEEECCCHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEEECCCCEEEEEEEEE
SNGTALKFLKEMNERYSQIRLLVVSGDDNNEIWQKVREAGGHGFVLKNESPELFAKAVAT
CCCHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHH
LTDNRLWFPQDNATGVTPVQNHLQHLNLTPRQVEVLAMMLRGFPNKRIASQLSISEPTVK
HHCCEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHH
EHISNILKKIGVNSRVEAITLLHGRSGPLQ
HHHHHHHHHCCCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure 
GQEYALVVDDHPLVASGIANFLNTHCRFKHVHMATNEDHCYRHIMLNGPPRLMVIDFWL
CCCEEEEEECCCHHHHHHHHHHHHCCEEEEEEECCCCCCEEEEEEECCCCEEEEEEEEE
SNGTALKFLKEMNERYSQIRLLVVSGDDNNEIWQKVREAGGHGFVLKNESPELFAKAVAT
CCCHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHH
LTDNRLWFPQDNATGVTPVQNHLQHLNLTPRQVEVLAMMLRGFPNKRIASQLSISEPTVK
HHCCEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHH
EHISNILKKIGVNSRVEAITLLHGRSGPLQ
HHHHHHHHHCCCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8898880; 9677290 [H]