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The map label for this gene is torS [H]

Identifier: 157371825

GI number: 157371825

Start: 3965741

End: 3967525

Strand: Direct

Name: torS [H]

Synonym: Spro_3590

Alternate gene names: 157371825

Gene position: 3965741-3967525 (Clockwise)

Preceding gene: 157371824

Following gene: 157371827

Centisome position: 72.78

GC content: 49.52

Gene sequence:

>1785_bases
ATGAAGTTACTTCAATCTTTACAAGATGATGGTATTTCTCCCCGTGCGCAAATCCGTCTGCTGGACAATACATTTATACG
CCTGGTATTTAGCTTCAGCGCAGTGCCCTTTGTTGGTATTCCTTTCGCTATTTGGATTTATTTACTGGGTGAAAACCTAT
GGCCGATTACCCTCTGGATAGTTTTATATTTGTTCTGCGCCGTCGCCATCAGGTTATGGCATCGCAGCTATAAGAGAGAA
ACAATAAAAAAAGATGCGGACTTTATTCTTCGCCGCTGGCTACCCCATATCAATAAAGTTGCCTTCGTTCATGGGCTGGG
TATTTCTTCGTTATATATAATCACGCCACAAATAAACAATTTTGACTTTTTCTTATTATTGAACATCAGTATCGCGGCTA
TCGTTGCGGCCAACGCAACACATTTAACGCCAGTCATTAGCGCCTTTACACTGTTTTTCTTTTCCTGCTGGAGCATACTG
AATATTGGCATCATCTGGCGATTAAACGATGTCATGCTTATTGTGCTGATGCTTAACCTGCTTTATGGGTTCGCCATCTA
CCGCCACGCATTAAGCTCCCATAAATTCTTTATCCAGCAAGCCCGTCTCGAAGAGGAAAGCTCCCGTCTTGCGGAGCAAT
TCAGGCAGGCCAAAGAGGAAGCAGAGCAGGCGTTATTGGATAAAAACCAATTTCTTACTACCGCCAGTCATGATTTGCGT
CAACCGGTGCACGCCATGGGTTTTTTGATCGAAGCCATTATCCATAAAAACCGCGATGTCACGCTCATCCCTCAGCTATT
GGATCTGCAGCAAAGCGTAAGATCCGTGCATCTTATGTTTAATTCCTTACTCGATCTCAGCAAGATTGAATCCGGCAACG
TCAGCACGGCAACGACCCATGTGGACATTGGAATACTGCTCGACTCGGTGATGACCCTGTTTCGCGAAGAGGCGAACAGC
CGGGCATTATCATTACGGGCATGGCGGCCCAAGCGCCGAATTTATGTGATGGGCGATCAGCTACTCATCAGGCAATCACT
GATTAACCTGATACAAAATGCACTGCGTTATACGCAAAAAGGAGGCGTGCTGATAGCCATTCGCCCTCAGGGAGCGGAAT
GCTTAATTGAAGTTTGGGACACCGGCGTTGGCATCGCCGACGAAGAGAAAGGCAAAGTTTTTTCCCCCTATTATCGCCCT
GAGCTGGCGTGGAAAATCGATAGTGCCGGCCACGGATTAGGGCTGGCGGTAGTGGCACGCTGCGCCAAACTGATGAAGGT
GAAATACGGCATGCAATCCGTTGAAGGCAAGGGTTCCCGTTTCTGGATGCGCTTTGCCCTTTACAACGGCGAATGCGAGC
TACCAGAAAGCGCAAACAGTTACTCAAATAGCCTCACTCCCCTCCGCTATGCGCCGCTGTACGGTTCCTGTCTGGTGGTG
GACGATGACCCACTGGTGACTTCCGCCTGGTCGAGTTTGATGAGCACCTGGGGCCTCACCGTACGCTGTGCGGCCTGTGC
AGAGGAGGCATTTGCGATTATCGATGAAGGCTTCAGCCCTTTTGCCGTGCTGTGCGATCAACGGCTCCGCTCTGGCGAGA
GCGGGTTCGATATATTGAAAGCGCTGTTTGAACGCCTGCCGAATACCAGCGGTGCCATGGTCAGCGGGGAATTTAACTCA
CCCACTTTGCAAGAGGCCGAACAGGAAGGTTATCTGGTACTGCGAAAACCGCTGGAACCCGCGAAACTCTATGCATTGCT
GTCGCAATGGGCAGCCTCCAGTTAG

Upstream 100 bases:

>100_bases
CCACAGTTAAAGAGCACATCAGTAATATTCTGAAAAAGATAGGTGTGAATAGTCGGGTAGAGGCGATCACCCTGCTCCAC
GGCAGATCGGGGCCATTACA

Downstream 100 bases:

>100_bases
CCGGGAGGCTTTATACCGGTGAACCCATGCCGGAATTCCGTTTCCCCATGGGTCCGATTTCAGGAGTGGCATTCCTTTAG
ATCTCAAGGCCGCGCAGCAG

Product: integral membrane sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MKLLQSLQDDGISPRAQIRLLDNTFIRLVFSFSAVPFVGIPFAIWIYLLGENLWPITLWIVLYLFCAVAIRLWHRSYKRE
TIKKDADFILRRWLPHINKVAFVHGLGISSLYIITPQINNFDFFLLLNISIAAIVAANATHLTPVISAFTLFFFSCWSIL
NIGIIWRLNDVMLIVLMLNLLYGFAIYRHALSSHKFFIQQARLEEESSRLAEQFRQAKEEAEQALLDKNQFLTTASHDLR
QPVHAMGFLIEAIIHKNRDVTLIPQLLDLQQSVRSVHLMFNSLLDLSKIESGNVSTATTHVDIGILLDSVMTLFREEANS
RALSLRAWRPKRRIYVMGDQLLIRQSLINLIQNALRYTQKGGVLIAIRPQGAECLIEVWDTGVGIADEEKGKVFSPYYRP
ELAWKIDSAGHGLGLAVVARCAKLMKVKYGMQSVEGKGSRFWMRFALYNGECELPESANSYSNSLTPLRYAPLYGSCLVV
DDDPLVTSAWSSLMSTWGLTVRCAACAEEAFAIIDEGFSPFAVLCDQRLRSGESGFDILKALFERLPNTSGAMVSGEFNS
PTLQEAEQEGYLVLRKPLEPAKLYALLSQWAASS

Sequences:

>Translated_594_residues
MKLLQSLQDDGISPRAQIRLLDNTFIRLVFSFSAVPFVGIPFAIWIYLLGENLWPITLWIVLYLFCAVAIRLWHRSYKRE
TIKKDADFILRRWLPHINKVAFVHGLGISSLYIITPQINNFDFFLLLNISIAAIVAANATHLTPVISAFTLFFFSCWSIL
NIGIIWRLNDVMLIVLMLNLLYGFAIYRHALSSHKFFIQQARLEEESSRLAEQFRQAKEEAEQALLDKNQFLTTASHDLR
QPVHAMGFLIEAIIHKNRDVTLIPQLLDLQQSVRSVHLMFNSLLDLSKIESGNVSTATTHVDIGILLDSVMTLFREEANS
RALSLRAWRPKRRIYVMGDQLLIRQSLINLIQNALRYTQKGGVLIAIRPQGAECLIEVWDTGVGIADEEKGKVFSPYYRP
ELAWKIDSAGHGLGLAVVARCAKLMKVKYGMQSVEGKGSRFWMRFALYNGECELPESANSYSNSLTPLRYAPLYGSCLVV
DDDPLVTSAWSSLMSTWGLTVRCAACAEEAFAIIDEGFSPFAVLCDQRLRSGESGFDILKALFERLPNTSGAMVSGEFNS
PTLQEAEQEGYLVLRKPLEPAKLYALLSQWAASS
>Mature_594_residues
MKLLQSLQDDGISPRAQIRLLDNTFIRLVFSFSAVPFVGIPFAIWIYLLGENLWPITLWIVLYLFCAVAIRLWHRSYKRE
TIKKDADFILRRWLPHINKVAFVHGLGISSLYIITPQINNFDFFLLLNISIAAIVAANATHLTPVISAFTLFFFSCWSIL
NIGIIWRLNDVMLIVLMLNLLYGFAIYRHALSSHKFFIQQARLEEESSRLAEQFRQAKEEAEQALLDKNQFLTTASHDLR
QPVHAMGFLIEAIIHKNRDVTLIPQLLDLQQSVRSVHLMFNSLLDLSKIESGNVSTATTHVDIGILLDSVMTLFREEANS
RALSLRAWRPKRRIYVMGDQLLIRQSLINLIQNALRYTQKGGVLIAIRPQGAECLIEVWDTGVGIADEEKGKVFSPYYRP
ELAWKIDSAGHGLGLAVVARCAKLMKVKYGMQSVEGKGSRFWMRFALYNGECELPESANSYSNSLTPLRYAPLYGSCLVV
DDDPLVTSAWSSLMSTWGLTVRCAACAEEAFAIIDEGFSPFAVLCDQRLRSGESGFDILKALFERLPNTSGAMVSGEFNS
PTLQEAEQEGYLVLRKPLEPAKLYALLSQWAASS

Specific function: Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Detects the presence of TMAO in the medium and, in response, activates torR via a four-step phosphorelay. When TMAO is removed,

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=352, Percent_Identity=29.8295454545455, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI48994928, Length=330, Percent_Identity=28.7878787878788, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=26.1044176706827, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1789149, Length=267, Percent_Identity=24.3445692883895, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1788393, Length=229, Percent_Identity=31.0043668122271, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788713, Length=351, Percent_Identity=26.2108262108262, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=26.9058295964126, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786783, Length=240, Percent_Identity=25.4166666666667, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1790551, Length=219, Percent_Identity=25.5707762557078, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=25.531914893617, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790346, Length=206, Percent_Identity=27.6699029126214, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI87082128, Length=242, Percent_Identity=23.5537190082645, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1786912, Length=223, Percent_Identity=27.8026905829596, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1787894, Length=254, Percent_Identity=22.4409448818898, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014302
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67012; Mature: 67012

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLQSLQDDGISPRAQIRLLDNTFIRLVFSFSAVPFVGIPFAIWIYLLGENLWPITLWI
CCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHH
VLYLFCAVAIRLWHRSYKRETIKKDADFILRRWLPHINKVAFVHGLGISSLYIITPQINN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCC
FDFFLLLNISIAAIVAANATHLTPVISAFTLFFFSCWSILNIGIIWRLNDVMLIVLMLNL
CCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHEEEHHHHHHHHHHHHH
LYGFAIYRHALSSHKFFIQQARLEEESSRLAEQFRQAKEEAEQALLDKNQFLTTASHDLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QPVHAMGFLIEAIIHKNRDVTLIPQLLDLQQSVRSVHLMFNSLLDLSKIESGNVSTATTH
HHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
VDIGILLDSVMTLFREEANSRALSLRAWRPKRRIYVMGDQLLIRQSLINLIQNALRYTQK
EHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHC
GGVLIAIRPQGAECLIEVWDTGVGIADEEKGKVFSPYYRPELAWKIDSAGHGLGLAVVAR
CCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCEECCCCCCCEEEEECCCCCCHHHHHHHH
CAKLMKVKYGMQSVEGKGSRFWMRFALYNGECELPESANSYSNSLTPLRYAPLYGSCLVV
HHHHHHHHHCHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCEEEE
DDDPLVTSAWSSLMSTWGLTVRCAACAEEAFAIIDEGFSPFAVLCDQRLRSGESGFDILK
CCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHH
ALFERLPNTSGAMVSGEFNSPTLQEAEQEGYLVLRKPLEPAKLYALLSQWAASS
HHHHHCCCCCCCEEECCCCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLLQSLQDDGISPRAQIRLLDNTFIRLVFSFSAVPFVGIPFAIWIYLLGENLWPITLWI
CCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHH
VLYLFCAVAIRLWHRSYKRETIKKDADFILRRWLPHINKVAFVHGLGISSLYIITPQINN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCC
FDFFLLLNISIAAIVAANATHLTPVISAFTLFFFSCWSILNIGIIWRLNDVMLIVLMLNL
CCEEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHEEEHHHHHHHHHHHHH
LYGFAIYRHALSSHKFFIQQARLEEESSRLAEQFRQAKEEAEQALLDKNQFLTTASHDLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QPVHAMGFLIEAIIHKNRDVTLIPQLLDLQQSVRSVHLMFNSLLDLSKIESGNVSTATTH
HHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEE
VDIGILLDSVMTLFREEANSRALSLRAWRPKRRIYVMGDQLLIRQSLINLIQNALRYTQK
EHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHC
GGVLIAIRPQGAECLIEVWDTGVGIADEEKGKVFSPYYRPELAWKIDSAGHGLGLAVVAR
CCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCEECCCCCCCEEEEECCCCCCHHHHHHHH
CAKLMKVKYGMQSVEGKGSRFWMRFALYNGECELPESANSYSNSLTPLRYAPLYGSCLVV
HHHHHHHHHCHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCEEEE
DDDPLVTSAWSSLMSTWGLTVRCAACAEEAFAIIDEGFSPFAVLCDQRLRSGESGFDILK
CCCCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHH
ALFERLPNTSGAMVSGEFNSPTLQEAEQEGYLVLRKPLEPAKLYALLSQWAASS
HHHHHCCCCCCCEEECCCCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]