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The map label for this gene is pta [H]

Identifier: 157371554

GI number: 157371554

Start: 3673293

End: 3675482

Strand: Direct

Name: pta [H]

Synonym: Spro_3317

Alternate gene names: 157371554

Gene position: 3673293-3675482 (Clockwise)

Preceding gene: 157371553

Following gene: 157371557

Centisome position: 67.41

GC content: 58.86

Gene sequence:

>2190_bases
ATGTTAAATCGTGAAGAGGACTATTCTGTGTCACGTACTATTATGTTGATCCCCACTGGCACCAGCGTCGGCCTGACCAG
CGTCAGCCTGGGTGTCATTCGCTCCATGGAGCAAAAAGGCGTTAGCCTGAGCGTATTCAAACCTATCGCACAGCCACGTA
CTGGCGGCGATTCGCTCGACCAGACCACCACCATCATCCGCAGCAGCAACTCCACCATCACGGCGGCAGAACCACTGCGC
ATGAGCTACGTTGAGGGCCTATTGAGCTCCAACCAGCAAGACGTGCTGATGGAAGAGATCGTGGCTCGCTACCACGAGAA
CACCAAAGACGCAGAAGTGGTGCTGATCGAAGGCCTGGTGCCGACCCGTAAGCACCAGTTCGCCAACGCGCTGAACTATG
AAATCGCCAAAACGCTGAATGCAGAAATCGTCTTCGTGCTGGCGCTGGGCAACGATTCCCCGGCACAGTTGAAAGAGCGT
ATCGAACTGGCGCGCAGCAGCTTCGGCGGCAGCAAAAACAAAAACATCACCGGCGTGATCATCAACAAGCTGAACGCCCC
GGTTGACGAGCAGGGCCGCACCCGTCCTGACCTGTCCGAAATCTTCGACGATTCCACCAAGGCCAGCGTGACCAACGTTG
ACCCGGCGCAACTGTTCGCCAACAGCCCGTTGCCGGTGCTGGGCTGCGTGCCGTGGAGCTTCGATCTGATCGCCACCCGC
GCTATCGACATGGCCCGTCACCTGAAGGCCTCCGTGGTCAATGAAGGCGACATCATGACCCGCCGCGTGAAGTCCGTGAC
TTTCTGTGCGCGCAGCATCCCGCACATGCTGGAACACTTCCGTCCGGGTTCACTGCTGGTAACTTCGGCAGACCGTCCTG
ACGTGCTGGTTTCTGCCTGTCTGGCAGCGATGAATGGCGTAGAGATCGGTGCCATCCTGCTGACCGGTGGCTACGCCATC
GACGAACCTATCAGAAAACTGTGTGAACGTGCCTTCCAGACCGGCCTGCCGGTATTTATGGTTGAAACCAACACCTGGCA
GACCTCGCTCAGCCTGCAAAGCTTTAACCTCGAAGTGCCGGCGGATGACCACCAGCGCATCGAGAAAGTGCAGAACTACG
TGGCCAGCCACATCAACGCCGAGTGGATCGAGTCTCTGACCGCCACCTCCGAGCGTTCACGTCGCCTGTCGCCACCAGCG
TTCCGTTACGAGCTGACCGAACTGGCACGTAAAGCCGGCAAACGCATCGTACTGCCTGAAGGCGACGAACCACGTACCGT
GAAAGCGGCGGCTATCTGTGCCGAACGTGGTATCGCTGAATGCGTGCTGTTGGGTAATCCGGAAGAGATCCAGCGCGTTG
CTGCCGCTCAGGGCGTTGAACTGGGCAAAGGCATCGAGATTGTTGATCCGGTCGCCGTCCGCGAACAGTATGTGCCGCGT
CTGGTTGAGCTGCGCAAGAGCAAGGGCATGACCGAAGTGGTTGCGCGTGAGCAACTGGAAGACAACGTGGTTCTCGGCAC
CCTGATGCTGGAGAAAGGCGAAGTTGACGGGCTGGTTTCCGGCGCGGTTCACACCACCGCCAACACCATTCGTCCACCGC
TGCAGTTGATCAAAACCGCACCGGGCAGCTCACTGGTGTCCTCCGTGTTCTTCATGCTGCTGCCTGACCAGGTTCTGGTG
TACGGCGACTGTGCGATCAACCCGGATCCAACCGCCGAGCAGCTGTCCGAGATCGCCATTCAGTCAGCCGACTCTGCTGC
CGCCTTCGGTATCGAACCACGCGTAGCGATGATCTCCTACTCCACCGGCAACTCAGGTGCGGGCAGCGACGTTGAGAAAG
TGCGCGAAGCAACCCGTCTGGCGCAGGAAAAACGTCCTGATCTGATCATCGATGGTCCGTTGCAGTATGACGCCGCGATC
ATGGCTGACGTAGCCAAATCCAAGGCGCCTAACTCGCCGGTTGCAGGCCAGGCTACCGTGTTCATCTTCCCGGATCTGAA
CACCGGTAACACCACCTACAAAGCGGTACAGCGTTCTGCTGACCTGGTGTCCATCGGGCCAATGCTGCAAGGCATGCGCA
AGCCGGTGAACGACCTGTCGCGTGGCGCACTGGTAGACGACATCGTTTACACCGTGGCGCTGACCGCCATCCAGTCTTCC
CAGGCTGATGCTGCAGCAGTCAAAGCCTGA

Upstream 100 bases:

>100_bases
CGACCAACGAAGAGTTGGTCATCGCGCAAGACGCATCCCGTCTGACCGCGTAACGCTCTCCGACACCGTCAGCCCAGGCT
GACGGTGCTGTTTTAGCCTC

Downstream 100 bases:

>100_bases
TAATTCCTGAATTATCAGATAAAAAAAAACCGGTCAATTGACCGGTTTTTTTATTTGCGCGAACACATCAGGCATTTTCA
TCGCTATCGCGTAGCGGCTT

Product: phosphate acetyltransferase

Products: NA

Alternate protein names: Phosphotransacetylase [H]

Number of amino acids: Translated: 729; Mature: 729

Protein sequence:

>729_residues
MLNREEDYSVSRTIMLIPTGTSVGLTSVSLGVIRSMEQKGVSLSVFKPIAQPRTGGDSLDQTTTIIRSSNSTITAAEPLR
MSYVEGLLSSNQQDVLMEEIVARYHENTKDAEVVLIEGLVPTRKHQFANALNYEIAKTLNAEIVFVLALGNDSPAQLKER
IELARSSFGGSKNKNITGVIINKLNAPVDEQGRTRPDLSEIFDDSTKASVTNVDPAQLFANSPLPVLGCVPWSFDLIATR
AIDMARHLKASVVNEGDIMTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVSACLAAMNGVEIGAILLTGGYAI
DEPIRKLCERAFQTGLPVFMVETNTWQTSLSLQSFNLEVPADDHQRIEKVQNYVASHINAEWIESLTATSERSRRLSPPA
FRYELTELARKAGKRIVLPEGDEPRTVKAAAICAERGIAECVLLGNPEEIQRVAAAQGVELGKGIEIVDPVAVREQYVPR
LVELRKSKGMTEVVAREQLEDNVVLGTLMLEKGEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPDQVLV
YGDCAINPDPTAEQLSEIAIQSADSAAAFGIEPRVAMISYSTGNSGAGSDVEKVREATRLAQEKRPDLIIDGPLQYDAAI
MADVAKSKAPNSPVAGQATVFIFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQSS
QADAAAVKA

Sequences:

>Translated_729_residues
MLNREEDYSVSRTIMLIPTGTSVGLTSVSLGVIRSMEQKGVSLSVFKPIAQPRTGGDSLDQTTTIIRSSNSTITAAEPLR
MSYVEGLLSSNQQDVLMEEIVARYHENTKDAEVVLIEGLVPTRKHQFANALNYEIAKTLNAEIVFVLALGNDSPAQLKER
IELARSSFGGSKNKNITGVIINKLNAPVDEQGRTRPDLSEIFDDSTKASVTNVDPAQLFANSPLPVLGCVPWSFDLIATR
AIDMARHLKASVVNEGDIMTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVSACLAAMNGVEIGAILLTGGYAI
DEPIRKLCERAFQTGLPVFMVETNTWQTSLSLQSFNLEVPADDHQRIEKVQNYVASHINAEWIESLTATSERSRRLSPPA
FRYELTELARKAGKRIVLPEGDEPRTVKAAAICAERGIAECVLLGNPEEIQRVAAAQGVELGKGIEIVDPVAVREQYVPR
LVELRKSKGMTEVVAREQLEDNVVLGTLMLEKGEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPDQVLV
YGDCAINPDPTAEQLSEIAIQSADSAAAFGIEPRVAMISYSTGNSGAGSDVEKVREATRLAQEKRPDLIIDGPLQYDAAI
MADVAKSKAPNSPVAGQATVFIFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQSS
QADAAAVKA
>Mature_729_residues
MLNREEDYSVSRTIMLIPTGTSVGLTSVSLGVIRSMEQKGVSLSVFKPIAQPRTGGDSLDQTTTIIRSSNSTITAAEPLR
MSYVEGLLSSNQQDVLMEEIVARYHENTKDAEVVLIEGLVPTRKHQFANALNYEIAKTLNAEIVFVLALGNDSPAQLKER
IELARSSFGGSKNKNITGVIINKLNAPVDEQGRTRPDLSEIFDDSTKASVTNVDPAQLFANSPLPVLGCVPWSFDLIATR
AIDMARHLKASVVNEGDIMTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVSACLAAMNGVEIGAILLTGGYAI
DEPIRKLCERAFQTGLPVFMVETNTWQTSLSLQSFNLEVPADDHQRIEKVQNYVASHINAEWIESLTATSERSRRLSPPA
FRYELTELARKAGKRIVLPEGDEPRTVKAAAICAERGIAECVLLGNPEEIQRVAAAQGVELGKGIEIVDPVAVREQYVPR
LVELRKSKGMTEVVAREQLEDNVVLGTLMLEKGEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPDQVLV
YGDCAINPDPTAEQLSEIAIQSADSAAAFGIEPRVAMISYSTGNSGAGSDVEKVREATRLAQEKRPDLIIDGPLQYDAAI
MADVAKSKAPNSPVAGQATVFIFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQSS
QADAAAVKA

Specific function: Conversion of acetate to acetyl-CoA; second step. [C]

COG id: COG0857

COG function: function code R; BioD-like N-terminal domain of phosphotransacetylase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788635, Length=712, Percent_Identity=88.2022471910112, Blast_Score=1302, Evalue=0.0,
Organism=Escherichia coli, GI1788800, Length=317, Percent_Identity=37.8548895899054, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI1788806, Length=346, Percent_Identity=30.9248554913295, Blast_Score=164, Evalue=1e-41,

Paralogues:

None

Copy number: 1420 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1250 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010766
- InterPro:   IPR016475
- InterPro:   IPR004614
- InterPro:   IPR002505 [H]

Pfam domain/function: PF07085 DRTGG; PF01515 PTA_PTB [H]

EC number: =2.3.1.8 [H]

Molecular weight: Translated: 78697; Mature: 78697

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNREEDYSVSRTIMLIPTGTSVGLTSVSLGVIRSMEQKGVSLSVFKPIAQPRTGGDSLD
CCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEHHCCCCCCCCCCCH
QTTTIIRSSNSTITAAEPLRMSYVEGLLSSNQQDVLMEEIVARYHENTKDAEVVLIEGLV
HHHHEEECCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCC
PTRKHQFANALNYEIAKTLNAEIVFVLALGNDSPAQLKERIELARSSFGGSKNKNITGVI
CCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEE
INKLNAPVDEQGRTRPDLSEIFDDSTKASVTNVDPAQLFANSPLPVLGCVPWSFDLIATR
EECCCCCCCCCCCCCCCHHHHHCCCCCCEECCCCHHHHHCCCCCCEEEECCCCHHHHHHH
AIDMARHLKASVVNEGDIMTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVSAC
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHH
LAAMNGVEIGAILLTGGYAIDEPIRKLCERAFQTGLPVFMVETNTWQTSLSLQSFNLEVP
HHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEEEECC
ADDHQRIEKVQNYVASHINAEWIESLTATSERSRRLSPPAFRYELTELARKAGKRIVLPE
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEECCC
GDEPRTVKAAAICAERGIAECVLLGNPEEIQRVAAAQGVELGKGIEIVDPVAVREQYVPR
CCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHH
LVELRKSKGMTEVVAREQLEDNVVLGTLMLEKGEVDGLVSGAVHTTANTIRPPLQLIKTA
HHHHHHHCCHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHCHHHHHHHHCCCHHHHHHCC
PGSSLVSSVFFMLLPDQVLVYGDCAINPDPTAEQLSEIAIQSADSAAAFGIEPRVAMISY
CCHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
STGNSGAGSDVEKVREATRLAQEKRPDLIIDGPLQYDAAIMADVAKSKAPNSPVAGQATV
ECCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEE
FIFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQSS
EEEECCCCCCHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCC
QADAAAVKA
CCCHHHCCC
>Mature Secondary Structure
MLNREEDYSVSRTIMLIPTGTSVGLTSVSLGVIRSMEQKGVSLSVFKPIAQPRTGGDSLD
CCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEEHHCCCCCCCCCCCH
QTTTIIRSSNSTITAAEPLRMSYVEGLLSSNQQDVLMEEIVARYHENTKDAEVVLIEGLV
HHHHEEECCCCEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCC
PTRKHQFANALNYEIAKTLNAEIVFVLALGNDSPAQLKERIELARSSFGGSKNKNITGVI
CCHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEEE
INKLNAPVDEQGRTRPDLSEIFDDSTKASVTNVDPAQLFANSPLPVLGCVPWSFDLIATR
EECCCCCCCCCCCCCCCHHHHHCCCCCCEECCCCHHHHHCCCCCCEEEECCCCHHHHHHH
AIDMARHLKASVVNEGDIMTRRVKSVTFCARSIPHMLEHFRPGSLLVTSADRPDVLVSAC
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHH
LAAMNGVEIGAILLTGGYAIDEPIRKLCERAFQTGLPVFMVETNTWQTSLSLQSFNLEVP
HHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEEEECC
ADDHQRIEKVQNYVASHINAEWIESLTATSERSRRLSPPAFRYELTELARKAGKRIVLPE
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEECCC
GDEPRTVKAAAICAERGIAECVLLGNPEEIQRVAAAQGVELGKGIEIVDPVAVREQYVPR
CCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCEECHHHHHHHHHHH
LVELRKSKGMTEVVAREQLEDNVVLGTLMLEKGEVDGLVSGAVHTTANTIRPPLQLIKTA
HHHHHHHCCHHHHHHHHHHCCCEEEEEEEEECCCCCHHHHCHHHHHHHHCCCHHHHHHCC
PGSSLVSSVFFMLLPDQVLVYGDCAINPDPTAEQLSEIAIQSADSAAAFGIEPRVAMISY
CCHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
STGNSGAGSDVEKVREATRLAQEKRPDLIIDGPLQYDAAIMADVAKSKAPNSPVAGQATV
ECCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEE
FIFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTVALTAIQSS
EEEECCCCCCHHHHHHHHCCCCEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCC
QADAAAVKA
CCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883769; 7918659; 9205837; 9278503; 2536666 [H]