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The map label for this gene is yfcG [H]

Identifier: 157371557

GI number: 157371557

Start: 3676998

End: 3677627

Strand: Direct

Name: yfcG [H]

Synonym: Spro_3320

Alternate gene names: 157371557

Gene position: 3676998-3677627 (Clockwise)

Preceding gene: 157371554

Following gene: 157371558

Centisome position: 67.48

GC content: 57.46

Gene sequence:

>630_bases
ATGATTGACCTGTATTACGCGCCTACTCCCAATGGTCACAAAATTACCCTGTTTCTGGAGGAGGTTGGCTTACCCTACCG
TATCCACCGCGTAAATATCAGCGCCGGCGATCAGTTCAAGCCGGATTTTCTGAGCATTTCACCCAACAACAAAATCCCGG
CCATCGTCGACCAGCAGCCGGTTGATGGCGGTGCGCCAATCAGCCTGTTCGAGTCCGGCGAAATTCTGCTGTATCTGGCG
GAGAAAACCGGCAAGCTGCTGAGCAAAGGGCTACGCGAGCGTGCAGCCACGCTACAGTGGCTGTTTTGGCAGGTGGCGGG
CTTTGGGCCGATGCTGGGGCAAAACCACCACTTCAACCACTACGCGCCGCAGCCGGTGCCCTACGCCATCGAACGTTATC
ACCTGGAAACCAAACGTCTGTATGCGGTGCTGGAAGCCGAGCTGCAAAAGCACCCTTATCTGGGCGGTGACAACTACAGC
ATTGCCGATATCGCCACCTATCCCTGGGTAGTGTCACACCCGCGTCAGCGCATCGATCTGGCGGATTATCCGGCGGTACG
CAACTGGTTCGAACGCATCAGCAACCGCCCGGCCACCGAGCGTGCCTACAAGCTGGCTGAGCAGGGTTAA

Upstream 100 bases:

>100_bases
GTTGGTAACCCTATAGAAAGATCTCTGATATACCTTTGTGCGCGGCGAAGACCGCAACAACGTGTAATGGCTTACAGATC
ACCTTACCGCAGGAGGCAAC

Downstream 100 bases:

>100_bases
TTTTCCGACTCCCCGGCCTCCGGGGAGTTTCCCCCGGCTCGTTATCATTTCCCTGCTTTCCGTGTATTCTGAGCACCAAT
AATCAGACCTGTGGAGATTC

Product: glutathione S-transferase domain-containing protein

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MIDLYYAPTPNGHKITLFLEEVGLPYRIHRVNISAGDQFKPDFLSISPNNKIPAIVDQQPVDGGAPISLFESGEILLYLA
EKTGKLLSKGLRERAATLQWLFWQVAGFGPMLGQNHHFNHYAPQPVPYAIERYHLETKRLYAVLEAELQKHPYLGGDNYS
IADIATYPWVVSHPRQRIDLADYPAVRNWFERISNRPATERAYKLAEQG

Sequences:

>Translated_209_residues
MIDLYYAPTPNGHKITLFLEEVGLPYRIHRVNISAGDQFKPDFLSISPNNKIPAIVDQQPVDGGAPISLFESGEILLYLA
EKTGKLLSKGLRERAATLQWLFWQVAGFGPMLGQNHHFNHYAPQPVPYAIERYHLETKRLYAVLEAELQKHPYLGGDNYS
IADIATYPWVVSHPRQRIDLADYPAVRNWFERISNRPATERAYKLAEQG
>Mature_209_residues
MIDLYYAPTPNGHKITLFLEEVGLPYRIHRVNISAGDQFKPDFLSISPNNKIPAIVDQQPVDGGAPISLFESGEILLYLA
EKTGKLLSKGLRERAATLQWLFWQVAGFGPMLGQNHHFNHYAPQPVPYAIERYHLETKRLYAVLEAELQKHPYLGGDNYS
IADIATYPWVVSHPRQRIDLADYPAVRNWFERISNRPATERAYKLAEQG

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=209, Percent_Identity=70.8133971291866, Blast_Score=308, Evalue=2e-85,
Organism=Escherichia coli, GI87082195, Length=215, Percent_Identity=41.3953488372093, Blast_Score=161, Evalue=3e-41,
Organism=Escherichia coli, GI87081789, Length=208, Percent_Identity=27.8846153846154, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324100, Length=234, Percent_Identity=30.7692307692308, Blast_Score=115, Evalue=7e-27,
Organism=Drosophila melanogaster, GI28571670, Length=176, Percent_Identity=28.4090909090909, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI85725204, Length=196, Percent_Identity=27.5510204081633, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17737923, Length=196, Percent_Identity=27.5510204081633, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI17864598, Length=203, Percent_Identity=29.064039408867, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17864592, Length=194, Percent_Identity=26.2886597938144, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI45549270, Length=193, Percent_Identity=25.3886010362694, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17864594, Length=195, Percent_Identity=25.1282051282051, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646249, Length=195, Percent_Identity=26.1538461538462, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 23828; Mature: 23828

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLYYAPTPNGHKITLFLEEVGLPYRIHRVNISAGDQFKPDFLSISPNNKIPAIVDQQP
CEEEEECCCCCCCEEEEEEHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCEEECCCC
VDGGAPISLFESGEILLYLAEKTGKLLSKGLRERAATLQWLFWQVAGFGPMLGQNHHFNH
CCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YAPQPVPYAIERYHLETKRLYAVLEAELQKHPYLGGDNYSIADIATYPWVVSHPRQRIDL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHCCCHHCCCHHHCCC
ADYPAVRNWFERISNRPATERAYKLAEQG
CCCHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MIDLYYAPTPNGHKITLFLEEVGLPYRIHRVNISAGDQFKPDFLSISPNNKIPAIVDQQP
CEEEEECCCCCCCEEEEEEHHCCCCEEEEEEEECCCCCCCCCEEEECCCCCCCEEECCCC
VDGGAPISLFESGEILLYLAEKTGKLLSKGLRERAATLQWLFWQVAGFGPMLGQNHHFNH
CCCCCCEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
YAPQPVPYAIERYHLETKRLYAVLEAELQKHPYLGGDNYSIADIATYPWVVSHPRQRIDL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHCCCHHCCCHHHCCC
ADYPAVRNWFERISNRPATERAYKLAEQG
CCCHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]