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The map label for this gene is appB [H]

Identifier: 157371096

GI number: 157371096

Start: 3134756

End: 3135724

Strand: Reverse

Name: appB [H]

Synonym: Spro_2856

Alternate gene names: 157371096

Gene position: 3135724-3134756 (Counterclockwise)

Preceding gene: 157371097

Following gene: 157371095

Centisome position: 57.55

GC content: 59.24

Gene sequence:

>969_bases
ATGGAAAACACCATGAGAAATTTTATCCTGCGCCGCCTGCTGCAAACCCTGCCGATGCTGCTGCTGGCATCACTGCTGAT
TTTCTTTATCTTCGCGCTGACGCCCGGCGATTTTATTGACGGCAACATTAACCTGACGCCGCAGCGCGCCGCCGAATTAC
GCGCGCTGTACGGGCTGGACCAGCCACTGCTGATCCGCTATTGGCACTGGCTCGGCCAACTGCTGCAAGGCAATCTCGGT
TTTTCGCTGCAGTACCAGATCCCGGTCAGCACCTTGTTGAATCAGTACATCTGGAATTCGTTCCTGCTGGCTTCGGTCGC
CCTGGTGCTGTACTGGGGCATTGCGCTGGCGGTTGGCGTGGCTTCGGCGATGAAACCCTATTCGCTGTTCGACCATCTGG
TCACGGTGGCGGTGTTCGGCGCCATGTCATTTCCGACCTTTTTCCTTTGCCTGCTGCTGATCAAATGGTTTGCCGTCGAT
CTGCATTGGCTGCCGGCGGGGGGCATGCTGCGCACCGGCAGCGAAGCGACCGGGCTGGCCTGGGTGGCAGAGGTGGCGGC
GCACCTGCTGTTGCCGGTGCTGGCGCTGGTGATGCTGCAGGCTGGTACCCTGACGCGCTATTTCCGCGCCAGCATGCTGG
ATGTGATCCGCATGGACTACATCCGCACCGCTCGCGCCAAAGGCCTGAAGGAGAAAACGGTGATCGTCAAACACGCGCTG
CGTAATGCCTTGCTGCCGATCATCACGCTGCTGGGGTTTGAATTACCGGCGCTGTTTTCCGGCGCGCTGATCACCGAAAA
AATCTTCAATTGGCCAGGGGCGGGGCACATCCACATCGACTCGCTGGCCGCCCGTGACTATCCGGTGCTGATGGGCTTCA
CGCTGTTTCTGGCGGTGCTGACCATTTTGGGCAATCTGCTGGCGGACATTCTGTACGCCTATGCCGACCCACGAATTCGT
TTGAGGTGA

Upstream 100 bases:

>100_bases
CTTTAAACCGGATGTCTACAATGGCCTGACCGGCAGCCTGCCGGACGTCAAACTGGCTCAGTAACGGCAAGGTACCGCCG
CGCTCCTCCGTGCGGCGGTA

Downstream 100 bases:

>100_bases
AGATGTTGTCAACGCTGTTTTTTGGACGCCGTCGCCGCTGGCGGCAGGCGCAACTTCCGGCGCTGGCGCAGCTGTCGCCA
CCCCCAACCGCACAGGCCTG

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MENTMRNFILRRLLQTLPMLLLASLLIFFIFALTPGDFIDGNINLTPQRAAELRALYGLDQPLLIRYWHWLGQLLQGNLG
FSLQYQIPVSTLLNQYIWNSFLLASVALVLYWGIALAVGVASAMKPYSLFDHLVTVAVFGAMSFPTFFLCLLLIKWFAVD
LHWLPAGGMLRTGSEATGLAWVAEVAAHLLLPVLALVMLQAGTLTRYFRASMLDVIRMDYIRTARAKGLKEKTVIVKHAL
RNALLPIITLLGFELPALFSGALITEKIFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTILGNLLADILYAYADPRIR
LR

Sequences:

>Translated_322_residues
MENTMRNFILRRLLQTLPMLLLASLLIFFIFALTPGDFIDGNINLTPQRAAELRALYGLDQPLLIRYWHWLGQLLQGNLG
FSLQYQIPVSTLLNQYIWNSFLLASVALVLYWGIALAVGVASAMKPYSLFDHLVTVAVFGAMSFPTFFLCLLLIKWFAVD
LHWLPAGGMLRTGSEATGLAWVAEVAAHLLLPVLALVMLQAGTLTRYFRASMLDVIRMDYIRTARAKGLKEKTVIVKHAL
RNALLPIITLLGFELPALFSGALITEKIFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTILGNLLADILYAYADPRIR
LR
>Mature_322_residues
MENTMRNFILRRLLQTLPMLLLASLLIFFIFALTPGDFIDGNINLTPQRAAELRALYGLDQPLLIRYWHWLGQLLQGNLG
FSLQYQIPVSTLLNQYIWNSFLLASVALVLYWGIALAVGVASAMKPYSLFDHLVTVAVFGAMSFPTFFLCLLLIKWFAVD
LHWLPAGGMLRTGSEATGLAWVAEVAAHLLLPVLALVMLQAGTLTRYFRASMLDVIRMDYIRTARAKGLKEKTVIVKHAL
RNALLPIITLLGFELPALFSGALITEKIFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVLTILGNLLADILYAYADPRIR
LR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=36.6071428571429, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI1787053, Length=323, Percent_Identity=36.5325077399381, Blast_Score=204, Evalue=4e-54,
Organism=Escherichia coli, GI1787497, Length=317, Percent_Identity=33.4384858044164, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1789888, Length=321, Percent_Identity=36.7601246105919, Blast_Score=184, Evalue=9e-48,
Organism=Escherichia coli, GI1787761, Length=330, Percent_Identity=35.4545454545455, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1788504, Length=366, Percent_Identity=28.4153005464481, Blast_Score=130, Evalue=8e-32,
Organism=Escherichia coli, GI1787550, Length=265, Percent_Identity=27.5471698113208, Blast_Score=111, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36001; Mature: 36001

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENTMRNFILRRLLQTLPMLLLASLLIFFIFALTPGDFIDGNINLTPQRAAELRALYGLD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHCCC
QPLLIRYWHWLGQLLQGNLGFSLQYQIPVSTLLNQYIWNSFLLASVALVLYWGIALAVGV
CHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASAMKPYSLFDHLVTVAVFGAMSFPTFFLCLLLIKWFAVDLHWLPAGGMLRTGSEATGLA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHH
WVAEVAAHLLLPVLALVMLQAGTLTRYFRASMLDVIRMDYIRTARAKGLKEKTVIVKHAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RNALLPIITLLGFELPALFSGALITEKIFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCCCHHHHHHHHHHHHH
TILGNLLADILYAYADPRIRLR
HHHHHHHHHHHHHHCCCCEECC
>Mature Secondary Structure
MENTMRNFILRRLLQTLPMLLLASLLIFFIFALTPGDFIDGNINLTPQRAAELRALYGLD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHHCCC
QPLLIRYWHWLGQLLQGNLGFSLQYQIPVSTLLNQYIWNSFLLASVALVLYWGIALAVGV
CHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASAMKPYSLFDHLVTVAVFGAMSFPTFFLCLLLIKWFAVDLHWLPAGGMLRTGSEATGLA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHH
WVAEVAAHLLLPVLALVMLQAGTLTRYFRASMLDVIRMDYIRTARAKGLKEKTVIVKHAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
RNALLPIITLLGFELPALFSGALITEKIFNWPGAGHIHIDSLAARDYPVLMGFTLFLAVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHCCCCHHHHHHHHHHHHH
TILGNLLADILYAYADPRIRLR
HHHHHHHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]