Click here to switch to the map view.

The map label for this gene is appC [H]

Identifier: 157371095

GI number: 157371095

Start: 3133803

End: 3134753

Strand: Reverse

Name: appC [H]

Synonym: Spro_2855

Alternate gene names: 157371095

Gene position: 3134753-3133803 (Counterclockwise)

Preceding gene: 157371096

Following gene: 157371094

Centisome position: 57.53

GC content: 61.93

Gene sequence:

>951_bases
ATGTTGTCAACGCTGTTTTTTGGACGCCGTCGCCGCTGGCGGCAGGCGCAACTTCCGGCGCTGGCGCAGCTGTCGCCACC
CCCAACCGCACAGGCCTGGCAACGGCTGCGGCGTCACCGGCTGGCGATGGCCTCGCTGCTGTTGCTGCTGATACTGGCGG
TGCTGTGCATCTTCGGGCCGATGCTGTCGCCCTGGCAGGACGATGCCGGTGATGCGCTAAACATCAACCAGGCACCCAAT
GCGGCACACTGGCTCGGCACCGATTTTCTCGGCCGTGATATTTATACGCGCCTGCTGCTGGCGGGGCGTATCTCACTGAC
CATCGGCCTGGTGTCGATGCTGCTGTCCGTCACGCTCGGCTACCTGCTGGGAGCACTGTCCGGCTATCTGGGCGGCATGG
TGGACAAGCTGATCATGCGCTTTGCCGATCTGCTGATGACCATCCCCAGCCTGCCGCTGCTGATCATTATGGGGGCGATG
CTGTCCGAGCTGGACGTCTCGCCGGACTACCGTATCTACATGGTGATGATCATGCTCAGCCTGCTGGGCTGGCCGTCATT
GGCGCGGCTGGTACGCGGCCAGATCCTGTCGCTGCGCGAGCGCGATTTTATGCTGGCGACCGAAGTGCTCGGGCTGTCTA
CCCGGCGGCGTTTGTTTGGTCATCTGTTGCCGAACACCATTCCCATCCTGGTGGTGGTGGCGACCATGGGCGTTGCCAAC
GCCATTCTCAGTGAGTCGGCACTTAGCTACCTGGGGCTGGGCGTGGTACCGCCGACACCGTCGTGGGGCAACATGATGGA
CGCCGCCAACAGCCTGATCGATTTTCAACGTCGTCCCTGGTTGTGGATGCCACCCGGCCTGGCGATTTTTATCACCGTGG
TAGCGATTAATATTCTGGGTGACGGCCTGCGGGACGCGCTCGATCCGAAAATGAACGGAGCAAGACCATGA

Upstream 100 bases:

>100_bases
TGGGCTTCACGCTGTTTCTGGCGGTGCTGACCATTTTGGGCAATCTGCTGGCGGACATTCTGTACGCCTATGCCGACCCA
CGAATTCGTTTGAGGTGAAG

Downstream 100 bases:

>100_bases
GCCGACCACTGCTGGCTTTTAATCAACTGTCGGTGGCCTTCAATGGCGAGCAGGGCCGGGTGCAGGCGGTGCAGCAACTG
AGTTTTGAACTGCATGCCGG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MLSTLFFGRRRRWRQAQLPALAQLSPPPTAQAWQRLRRHRLAMASLLLLLILAVLCIFGPMLSPWQDDAGDALNINQAPN
AAHWLGTDFLGRDIYTRLLLAGRISLTIGLVSMLLSVTLGYLLGALSGYLGGMVDKLIMRFADLLMTIPSLPLLIIMGAM
LSELDVSPDYRIYMVMIMLSLLGWPSLARLVRGQILSLRERDFMLATEVLGLSTRRRLFGHLLPNTIPILVVVATMGVAN
AILSESALSYLGLGVVPPTPSWGNMMDAANSLIDFQRRPWLWMPPGLAIFITVVAINILGDGLRDALDPKMNGARP

Sequences:

>Translated_316_residues
MLSTLFFGRRRRWRQAQLPALAQLSPPPTAQAWQRLRRHRLAMASLLLLLILAVLCIFGPMLSPWQDDAGDALNINQAPN
AAHWLGTDFLGRDIYTRLLLAGRISLTIGLVSMLLSVTLGYLLGALSGYLGGMVDKLIMRFADLLMTIPSLPLLIIMGAM
LSELDVSPDYRIYMVMIMLSLLGWPSLARLVRGQILSLRERDFMLATEVLGLSTRRRLFGHLLPNTIPILVVVATMGVAN
AILSESALSYLGLGVVPPTPSWGNMMDAANSLIDFQRRPWLWMPPGLAIFITVVAINILGDGLRDALDPKMNGARP
>Mature_316_residues
MLSTLFFGRRRRWRQAQLPALAQLSPPPTAQAWQRLRRHRLAMASLLLLLILAVLCIFGPMLSPWQDDAGDALNINQAPN
AAHWLGTDFLGRDIYTRLLLAGRISLTIGLVSMLLSVTLGYLLGALSGYLGGMVDKLIMRFADLLMTIPSLPLLIIMGAM
LSELDVSPDYRIYMVMIMLSLLGWPSLARLVRGQILSLRERDFMLATEVLGLSTRRRLFGHLLPNTIPILVVVATMGVAN
AILSESALSYLGLGVVPPTPSWGNMMDAANSLIDFQRRPWLWMPPGLAIFITVVAINILGDGLRDALDPKMNGARP

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=305, Percent_Identity=40, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI1787498, Length=285, Percent_Identity=39.2982456140351, Blast_Score=174, Evalue=9e-45,
Organism=Escherichia coli, GI1787760, Length=281, Percent_Identity=34.8754448398576, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789889, Length=234, Percent_Identity=41.8803418803419, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1789964, Length=293, Percent_Identity=36.1774744027304, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1787549, Length=293, Percent_Identity=33.4470989761092, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1788505, Length=233, Percent_Identity=32.618025751073, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34833; Mature: 34833

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTLFFGRRRRWRQAQLPALAQLSPPPTAQAWQRLRRHRLAMASLLLLLILAVLCIFGP
CCCHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MLSPWQDDAGDALNINQAPNAAHWLGTDFLGRDIYTRLLLAGRISLTIGLVSMLLSVTLG
CCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLLGALSGYLGGMVDKLIMRFADLLMTIPSLPLLIIMGAMLSELDVSPDYRIYMVMIMLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LLGWPSLARLVRGQILSLRERDFMLATEVLGLSTRRRLFGHLLPNTIPILVVVATMGVAN
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AILSESALSYLGLGVVPPTPSWGNMMDAANSLIDFQRRPWLWMPPGLAIFITVVAINILG
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHH
DGLRDALDPKMNGARP
HHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLSTLFFGRRRRWRQAQLPALAQLSPPPTAQAWQRLRRHRLAMASLLLLLILAVLCIFGP
CCCHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MLSPWQDDAGDALNINQAPNAAHWLGTDFLGRDIYTRLLLAGRISLTIGLVSMLLSVTLG
CCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLLGALSGYLGGMVDKLIMRFADLLMTIPSLPLLIIMGAMLSELDVSPDYRIYMVMIMLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LLGWPSLARLVRGQILSLRERDFMLATEVLGLSTRRRLFGHLLPNTIPILVVVATMGVAN
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AILSESALSYLGLGVVPPTPSWGNMMDAANSLIDFQRRPWLWMPPGLAIFITVVAINILG
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHH
DGLRDALDPKMNGARP
HHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]