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The map label for this gene is dadA

Identifier: 157370986

GI number: 157370986

Start: 3025438

End: 3026742

Strand: Reverse

Name: dadA

Synonym: Spro_2746

Alternate gene names: 157370986

Gene position: 3026742-3025438 (Counterclockwise)

Preceding gene: 157370988

Following gene: 157370985

Centisome position: 55.55

GC content: 57.24

Gene sequence:

>1305_bases
ATGCGAGTGGTAATTTTAGGTAGTGGAGTGGTGGGTGTTGCCAGCGCCTGGTATTTGGCGAAAGCGGGGCATGAGGTGAC
GGTTATCGATCGTCAACCCGGCCCGGCGATGGAAACCAGTGCGGCGAATGCCGGTCAGATCTCACCGGGCTATGCGGCTC
CGTGGGCTGCGCCTGGCGTGCCTTTGAAGGCGGTTAAATGGATGTTCCAGCGCCATGCGCCTTTGGCGGTTCGTCTGGAC
GGCAGCAGCTTCCAATTGAGCTGGATGTGGCAGATGCTCAAAAACTGCAATACCGAACACTACATGACCAATAAAGGGCG
TATGGTGCGGCTGGCGGAATACAGTCGTGACTGTATCAAGGCGCTGCGCCAGGAAACCGGCATCCAGTATGAAGGCCGTC
AGGGCGGGACGCTGCAACTGTTCCGTACCCAGCAACAGTTTGAAAGTGCGGCGAAAGACATCGCGGTGTTGGAAGATGCC
GGCGTGCCCTACAAACTGCTGGAAGCCAGTCAGTTGGCCAGCGTTGAACCTGCACTTGCGCAGGTGGCACATAAGCTGAC
CGGTGGGCTGCAACTGCCTAACGATGAAACCGGCGACTGCCAACTCTTTACCCAGCAACTGGCCAAACTGGCGCAGCAGG
CCGGAGTTACTTTCCTGTATAACCGCAGCGTCGATCGCCTGCTGGTGGAAGGGGACAAGATCAGCGGTGTGCAATGTGGC
GGAGAAATCTTCAAAGCCGACAGCTACGTGGTGGCCTTTGGTTCTTATTCCACCGCGCTGTTGCGTGACCTGGTGTCGAT
CCCTGTCTATCCGCTGAAAGGCTACTCGCTGACCATTCCTATTACCGATGAGTCCGCCGCACCGTTCTCAACCGTGCTGG
ATGAAACTTACAAAATCGCCATTACCCGTTTCGATCAGCGTATTCGCGTCGGCGGCATGGCGGAAATTGTTGGTTTTAAC
ACGCAGCTTGAACAAAAGCGTAGAGAGACGCTGGAGATGGTGGTGCGCGACCTTTACCCTAACGGTGGACGGGTGGAAGA
CGCTACCTTCTGGACCGGTTTACGGCCGATGACGCCGGACGGCACGCCAATTGTCGGCAAGACCTCGCTGAAAAATCTGT
TCCTGAATACCGGCCACGGCACCCTGGGCTGGACCATGGCCTGTGGTTCCGGCCAACTGCTTTCCGATTTGATTTCCGGT
ATCACGCCGGCCATTCCTTCAGACGATCTGGGAGTGGCACGTTACAGCGCCGGATTTCGCAGCCTCTACACCGGCCCCTT
GAACGATGTGCATCCCGCGCGTTAA

Upstream 100 bases:

>100_bases
GTCACGTTTGATGACGAAGATGTTGGACGGATTTTTCCACTGAGTTAATTTCCTGTGAGCAGAAGATTATGCTTTGTGAA
GCCTTAAGCTGGAGTCAGCG

Downstream 100 bases:

>100_bases
AAACCCTAATTTATAATGTTATTGTCACGGGCGTTGGCCCGTGACCGCATTTGCCGGCCCGTAGGAGTGCCCATGCCTCG
CCCGATTTCCGCCACGTTAC

Product: D-amino acid dehydrogenase small subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRVVILGSGVVGVASAWYLAKAGHEVTVIDRQPGPAMETSAANAGQISPGYAAPWAAPGVPLKAVKWMFQRHAPLAVRLD
GSSFQLSWMWQMLKNCNTEHYMTNKGRMVRLAEYSRDCIKALRQETGIQYEGRQGGTLQLFRTQQQFESAAKDIAVLEDA
GVPYKLLEASQLASVEPALAQVAHKLTGGLQLPNDETGDCQLFTQQLAKLAQQAGVTFLYNRSVDRLLVEGDKISGVQCG
GEIFKADSYVVAFGSYSTALLRDLVSIPVYPLKGYSLTIPITDESAAPFSTVLDETYKIAITRFDQRIRVGGMAEIVGFN
TQLEQKRRETLEMVVRDLYPNGGRVEDATFWTGLRPMTPDGTPIVGKTSLKNLFLNTGHGTLGWTMACGSGQLLSDLISG
ITPAIPSDDLGVARYSAGFRSLYTGPLNDVHPAR

Sequences:

>Translated_434_residues
MRVVILGSGVVGVASAWYLAKAGHEVTVIDRQPGPAMETSAANAGQISPGYAAPWAAPGVPLKAVKWMFQRHAPLAVRLD
GSSFQLSWMWQMLKNCNTEHYMTNKGRMVRLAEYSRDCIKALRQETGIQYEGRQGGTLQLFRTQQQFESAAKDIAVLEDA
GVPYKLLEASQLASVEPALAQVAHKLTGGLQLPNDETGDCQLFTQQLAKLAQQAGVTFLYNRSVDRLLVEGDKISGVQCG
GEIFKADSYVVAFGSYSTALLRDLVSIPVYPLKGYSLTIPITDESAAPFSTVLDETYKIAITRFDQRIRVGGMAEIVGFN
TQLEQKRRETLEMVVRDLYPNGGRVEDATFWTGLRPMTPDGTPIVGKTSLKNLFLNTGHGTLGWTMACGSGQLLSDLISG
ITPAIPSDDLGVARYSAGFRSLYTGPLNDVHPAR
>Mature_434_residues
MRVVILGSGVVGVASAWYLAKAGHEVTVIDRQPGPAMETSAANAGQISPGYAAPWAAPGVPLKAVKWMFQRHAPLAVRLD
GSSFQLSWMWQMLKNCNTEHYMTNKGRMVRLAEYSRDCIKALRQETGIQYEGRQGGTLQLFRTQQQFESAAKDIAVLEDA
GVPYKLLEASQLASVEPALAQVAHKLTGGLQLPNDETGDCQLFTQQLAKLAQQAGVTFLYNRSVDRLLVEGDKISGVQCG
GEIFKADSYVVAFGSYSTALLRDLVSIPVYPLKGYSLTIPITDESAAPFSTVLDETYKIAITRFDQRIRVGGMAEIVGFN
TQLEQKRRETLEMVVRDLYPNGGRVEDATFWTGLRPMTPDGTPIVGKTSLKNLFLNTGHGTLGWTMACGSGQLLSDLISG
ITPAIPSDDLGVARYSAGFRSLYTGPLNDVHPAR

Specific function: Oxidative deamination of D-amino acids

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family

Homologues:

Organism=Homo sapiens, GI194306651, Length=325, Percent_Identity=24, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1787438, Length=431, Percent_Identity=80.2784222737819, Blast_Score=733, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DADA_SERP5 (A8GFF7)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001478975.1
- ProteinModelPortal:   A8GFF7
- STRING:   A8GFF7
- GeneID:   5607031
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2746
- eggNOG:   COG0665
- HOGENOM:   HBG729204
- OMA:   WQMLQNC
- ProtClustDB:   PRK00711
- BioCyc:   SPRO399741:SPRO_2746-MONOMER
- HAMAP:   MF_01202
- InterPro:   IPR023080
- InterPro:   IPR006076

Pfam domain/function: PF01266 DAO

EC number: =1.4.99.1

Molecular weight: Translated: 47213; Mature: 47213

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVILGSGVVGVASAWYLAKAGHEVTVIDRQPGPAMETSAANAGQISPGYAAPWAAPGV
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PLKAVKWMFQRHAPLAVRLDGSSFQLSWMWQMLKNCNTEHYMTNKGRMVRLAEYSRDCIK
CHHHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHHCCCCEEECCCCCEEEHHHHHHHHHH
ALRQETGIQYEGRQGGTLQLFRTQQQFESAAKDIAVLEDAGVPYKLLEASQLASVEPALA
HHHHHCCCEECCCCCCEEEEEECHHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCHHHH
QVAHKLTGGLQLPNDETGDCQLFTQQLAKLAQQAGVTFLYNRSVDRLLVEGDKISGVQCG
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCCCCCEECC
GEIFKADSYVVAFGSYSTALLRDLVSIPVYPLKGYSLTIPITDESAAPFSTVLDETYKIA
CCEEECCCEEEEECCCHHHHHHHHHHCCCEEECCCEEEEEECCCCCCCHHHHHHHHHEEE
ITRFDQRIRVGGMAEIVGFNTQLEQKRRETLEMVVRDLYPNGGRVEDATFWTGLRPMTPD
EEECCCHHCCCCEEHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCC
GTPIVGKTSLKNLFLNTGHGTLGWTMACGSGQLLSDLISGITPAIPSDDLGVARYSAGFR
CCEEECCHHHHHHEEECCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHCCHH
SLYTGPLNDVHPAR
HHCCCCCCCCCCCC
>Mature Secondary Structure
MRVVILGSGVVGVASAWYLAKAGHEVTVIDRQPGPAMETSAANAGQISPGYAAPWAAPGV
CEEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PLKAVKWMFQRHAPLAVRLDGSSFQLSWMWQMLKNCNTEHYMTNKGRMVRLAEYSRDCIK
CHHHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHHCCCCEEECCCCCEEEHHHHHHHHHH
ALRQETGIQYEGRQGGTLQLFRTQQQFESAAKDIAVLEDAGVPYKLLEASQLASVEPALA
HHHHHCCCEECCCCCCEEEEEECHHHHHHHHHHEEEECCCCCCHHHHHHHHHHCCCHHHH
QVAHKLTGGLQLPNDETGDCQLFTQQLAKLAQQAGVTFLYNRSVDRLLVEGDKISGVQCG
HHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCCCCCEECC
GEIFKADSYVVAFGSYSTALLRDLVSIPVYPLKGYSLTIPITDESAAPFSTVLDETYKIA
CCEEECCCEEEEECCCHHHHHHHHHHCCCEEECCCEEEEEECCCCCCCHHHHHHHHHEEE
ITRFDQRIRVGGMAEIVGFNTQLEQKRRETLEMVVRDLYPNGGRVEDATFWTGLRPMTPD
EEECCCHHCCCCEEHEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCC
GTPIVGKTSLKNLFLNTGHGTLGWTMACGSGQLLSDLISGITPAIPSDDLGVARYSAGFR
CCEEECCHHHHHHEEECCCCCCEEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHCCHH
SLYTGPLNDVHPAR
HHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA