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The map label for this gene is alr [H]

Identifier: 157370985

GI number: 157370985

Start: 3024292

End: 3025365

Strand: Reverse

Name: alr [H]

Synonym: Spro_2745

Alternate gene names: 157370985

Gene position: 3025365-3024292 (Counterclockwise)

Preceding gene: 157370986

Following gene: 157370977

Centisome position: 55.52

GC content: 59.31

Gene sequence:

>1074_bases
ATGCCTCGCCCGATTTCCGCCACGTTACACCTTGGCGCTTTTGAAAATAACCTGCAGGTGGTTCGCCGTTTCGCCCCCAA
AGCCAAAGTCTGGTCGGTGGTCAAGGCCAATGCCTATGGTCACGGTATCAAACATGTCTGGCGCAGTCTGGCGCAGACCG
ACGGTTTTGCCTTGCTGGATCTGGCCGAAGCCATTTTGCTGCGTGAGTCCGGCTGGCAAGGACCGATTTTGTTGCTGGAA
GGTTTTTTCAAGCCACAGGATTTGGCCCTGCTGGACCGCTATCGTTTGACGACCTCGGTACACAGCGACTGGCAACTGGC
GGCGATAGCCGAGGCCAAACTGTCGGCACCGCTGGATGTTTATCTGAAAGTGAACAGTGGCATGAACCGTCTGGGTTTTG
CACCGGAACGCTTGCACGCTGTCTGGATGAAGGCTCAGGAGATCGGCAACATAGCCAGCCTGACGCTGATGAGCCATTTC
GCCACCGCGGACGGTCCACAGGGCGTCGAGGCGCAAATGGCCAGCATAGAACGGGCGGCGAAGGGCATCACTTTGCCGCG
CTGTCTGGCCAACTCTGCCGCTACGCTGTGGCACCCGCAAACCCATGGCAGTTGGGTGCGGCCGGGCATTGTGCTCTATG
GCGCTTCACCAAGCGGCCAATGGCGTGACATTGCCGACAGCGGTCTGCAACCCACCATGACGCTGAGTAGCGAAATTATC
GGTGTTCAAACGCTGAAGTCCGGTGATCAGGTGGGTTATGGCTGGCGTTACCGCGCCGAGGGAGCGCAACGCATCGGCGT
GGTAGCCTGTGGTTATGCCGATGGTTATCCGCGTCATGCGCAAACCGGTACGCCAGTCTGGGTGGACGGTGTGCTGACAC
GAACGTTAGGCACGGTTTCAATGGATATGCTGGTGGTCGATCTGACGCCTTGCCCGCATGCGGGTATCGGGGCGGAAGTG
GAACTGTGGGGGCGGCGCCTGCCGGTTGACGATGTCGCCACCGCGGCAGGTACGCTGGGTTATGAATTACTGACGGCACT
GGCCGCTAGAGTGCCAATCAACACCGAGGCCTAA

Upstream 100 bases:

>100_bases
CTTGAACGATGTGCATCCCGCGCGTTAAAAACCCTAATTTATAATGTTATTGTCACGGGCGTTGGCCCGTGACCGCATTT
GCCGGCCCGTAGGAGTGCCC

Downstream 100 bases:

>100_bases
GCCTCAGGCAATCTTCTTCAACTGACCTTTTATTTGCTTGCTGCGCTGTCGTGCGTGCAGCGCTAGCAGGCAACCCACCA
GCATCACCAGCGCCAGTGAC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MPRPISATLHLGAFENNLQVVRRFAPKAKVWSVVKANAYGHGIKHVWRSLAQTDGFALLDLAEAILLRESGWQGPILLLE
GFFKPQDLALLDRYRLTTSVHSDWQLAAIAEAKLSAPLDVYLKVNSGMNRLGFAPERLHAVWMKAQEIGNIASLTLMSHF
ATADGPQGVEAQMASIERAAKGITLPRCLANSAATLWHPQTHGSWVRPGIVLYGASPSGQWRDIADSGLQPTMTLSSEII
GVQTLKSGDQVGYGWRYRAEGAQRIGVVACGYADGYPRHAQTGTPVWVDGVLTRTLGTVSMDMLVVDLTPCPHAGIGAEV
ELWGRRLPVDDVATAAGTLGYELLTALAARVPINTEA

Sequences:

>Translated_357_residues
MPRPISATLHLGAFENNLQVVRRFAPKAKVWSVVKANAYGHGIKHVWRSLAQTDGFALLDLAEAILLRESGWQGPILLLE
GFFKPQDLALLDRYRLTTSVHSDWQLAAIAEAKLSAPLDVYLKVNSGMNRLGFAPERLHAVWMKAQEIGNIASLTLMSHF
ATADGPQGVEAQMASIERAAKGITLPRCLANSAATLWHPQTHGSWVRPGIVLYGASPSGQWRDIADSGLQPTMTLSSEII
GVQTLKSGDQVGYGWRYRAEGAQRIGVVACGYADGYPRHAQTGTPVWVDGVLTRTLGTVSMDMLVVDLTPCPHAGIGAEV
ELWGRRLPVDDVATAAGTLGYELLTALAARVPINTEA
>Mature_356_residues
PRPISATLHLGAFENNLQVVRRFAPKAKVWSVVKANAYGHGIKHVWRSLAQTDGFALLDLAEAILLRESGWQGPILLLEG
FFKPQDLALLDRYRLTTSVHSDWQLAAIAEAKLSAPLDVYLKVNSGMNRLGFAPERLHAVWMKAQEIGNIASLTLMSHFA
TADGPQGVEAQMASIERAAKGITLPRCLANSAATLWHPQTHGSWVRPGIVLYGASPSGQWRDIADSGLQPTMTLSSEIIG
VQTLKSGDQVGYGWRYRAEGAQRIGVVACGYADGYPRHAQTGTPVWVDGVLTRTLGTVSMDMLVVDLTPCPHAGIGAEVE
LWGRRLPVDDVATAAGTLGYELLTALAARVPINTEA

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=355, Percent_Identity=66.7605633802817, Blast_Score=501, Evalue=1e-143,
Organism=Escherichia coli, GI1790487, Length=345, Percent_Identity=43.4782608695652, Blast_Score=276, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 38547; Mature: 38415

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPISATLHLGAFENNLQVVRRFAPKAKVWSVVKANAYGHGIKHVWRSLAQTDGFALLD
CCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHEECCCCCCHHHHHHHHHHHCCCCHHHH
LAEAILLRESGWQGPILLLEGFFKPQDLALLDRYRLTTSVHSDWQLAAIAEAKLSAPLDV
HHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCEEE
YLKVNSGMNRLGFAPERLHAVWMKAQEIGNIASLTLMSHFATADGPQGVEAQMASIERAA
EEEECCCCHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KGITLPRCLANSAATLWHPQTHGSWVRPGIVLYGASPSGQWRDIADSGLQPTMTLSSEII
CCCCHHHHHHCCCCEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHCCCCCEEEHHHHHH
GVQTLKSGDQVGYGWRYRAEGAQRIGVVACGYADGYPRHAQTGTPVWVDGVLTRTLGTVS
EEEEECCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHE
MDMLVVDLTPCPHAGIGAEVELWGRRLPVDDVATAAGTLGYELLTALAARVPINTEA
EEEEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PRPISATLHLGAFENNLQVVRRFAPKAKVWSVVKANAYGHGIKHVWRSLAQTDGFALLD
CCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHEECCCCCCHHHHHHHHHHHCCCCHHHH
LAEAILLRESGWQGPILLLEGFFKPQDLALLDRYRLTTSVHSDWQLAAIAEAKLSAPLDV
HHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCEEE
YLKVNSGMNRLGFAPERLHAVWMKAQEIGNIASLTLMSHFATADGPQGVEAQMASIERAA
EEEECCCCHHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
KGITLPRCLANSAATLWHPQTHGSWVRPGIVLYGASPSGQWRDIADSGLQPTMTLSSEII
CCCCHHHHHHCCCCEEECCCCCCCCCCCCEEEEECCCCCCCHHHHHCCCCCEEEHHHHHH
GVQTLKSGDQVGYGWRYRAEGAQRIGVVACGYADGYPRHAQTGTPVWVDGVLTRTLGTVS
EEEEECCCCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHE
MDMLVVDLTPCPHAGIGAEVELWGRRLPVDDVATAAGTLGYELLTALAARVPINTEA
EEEEEEEECCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA