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The map label for this gene is tdk [H]

Identifier: 157370945

GI number: 157370945

Start: 2981414

End: 2981998

Strand: Reverse

Name: tdk [H]

Synonym: Spro_2705

Alternate gene names: 157370945

Gene position: 2981998-2981414 (Counterclockwise)

Preceding gene: 157370947

Following gene: 157370943

Centisome position: 54.73

GC content: 49.57

Gene sequence:

>585_bases
ATGGCTCAACTTTATTTTTATTACTCTGCTATGAACGCAGGGAAATCTACCGCGTTGTTGCAATCTTCATATAATTATCA
AGAGCGTGGTATGCGCACGTTGGTGTTTACCGCCGAAATAGATCATCGATTTGGTGTCGGTAAGGTCAGCTCGCGGATCG
GGCTGTCGTCACAGGCGCAGCTCTATAATAATGAGTCGATGCTCTATGCGATGATTGCACAGGAACATCAACAGCAACTG
GTACATTGCGTGTTGTTGGATGAAAGTCAGTTCCTGACGAAACAGCAGGTTGAGCAATTGTGTGATGTCGTCGACCAACT
GGATATTCCGGTTCTGTGTTATGGCTTGCGTACCGACTTCCTGGGGGAACTGTTCATTGGCAGCCAATACTTGCTGGCCT
GGGCAGACAAACTGGTAGAGTTGAAAACCATCTGCCATTGCGGACGCAAGGCCAATATGGTGCTACGGCTGGATGAAAGC
GGGCAGGCTATGCATGCCGGTGAGCAGGTAGTGATAGGGGGGAACGAGAGCTATGTCTCCGTTTGCCGCAAGCATTACAA
GGAAGCCATACAGGCACTGGAGTAG

Upstream 100 bases:

>100_bases
GTTGATTAACCCGGAGGCGTGAGCAGGCCGATAGGTTATGGTACACTTTACCTCTGAATCAACCTTCGAATATTTCTTAT
ACCATTGGAGTTGCGGGCCC

Downstream 100 bases:

>100_bases
CGTTTAGAACGCCGCAGGGAGCCCTGTGGCGTGTTTGAGCGCTATTGCGCACTCAGGTAAGTACTGGCCAACGTGCCGCA
TAAAAAAACCGCCTTTCGGC

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTLVFTAEIDHRFGVGKVSSRIGLSSQAQLYNNESMLYAMIAQEHQQQL
VHCVLLDESQFLTKQQVEQLCDVVDQLDIPVLCYGLRTDFLGELFIGSQYLLAWADKLVELKTICHCGRKANMVLRLDES
GQAMHAGEQVVIGGNESYVSVCRKHYKEAIQALE

Sequences:

>Translated_194_residues
MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTLVFTAEIDHRFGVGKVSSRIGLSSQAQLYNNESMLYAMIAQEHQQQL
VHCVLLDESQFLTKQQVEQLCDVVDQLDIPVLCYGLRTDFLGELFIGSQYLLAWADKLVELKTICHCGRKANMVLRLDES
GQAMHAGEQVVIGGNESYVSVCRKHYKEAIQALE
>Mature_193_residues
AQLYFYYSAMNAGKSTALLQSSYNYQERGMRTLVFTAEIDHRFGVGKVSSRIGLSSQAQLYNNESMLYAMIAQEHQQQLV
HCVLLDESQFLTKQQVEQLCDVVDQLDIPVLCYGLRTDFLGELFIGSQYLLAWADKLVELKTICHCGRKANMVLRLDESG
QAMHAGEQVVIGGNESYVSVCRKHYKEAIQALE

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=191, Percent_Identity=80.1047120418848, Blast_Score=322, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 21946; Mature: 21815

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTLVFTAEIDHRFGVGKVSSRIGLSSQAQ
CCEEEEEEEECCCCCHHHHHHCCCCHHHCCCEEEEEEEECCCCCCCCHHHHHCCCCCCHH
LYNNESMLYAMIAQEHQQQLVHCVLLDESQFLTKQQVEQLCDVVDQLDIPVLCYGLRTDF
HHCCCCHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHH
LGELFIGSQYLLAWADKLVELKTICHCGRKANMVLRLDESGQAMHAGEQVVIGGNESYVS
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCEEEECCCHHHHH
VCRKHYKEAIQALE
HHHHHHHHHHHHCC
>Mature Secondary Structure 
AQLYFYYSAMNAGKSTALLQSSYNYQERGMRTLVFTAEIDHRFGVGKVSSRIGLSSQAQ
CEEEEEEEECCCCCHHHHHHCCCCHHHCCCEEEEEEEECCCCCCCCHHHHHCCCCCCHH
LYNNESMLYAMIAQEHQQQLVHCVLLDESQFLTKQQVEQLCDVVDQLDIPVLCYGLRTDF
HHCCCCHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHH
LGELFIGSQYLLAWADKLVELKTICHCGRKANMVLRLDESGQAMHAGEQVVIGGNESYVS
HHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCEEEECCCHHHHH
VCRKHYKEAIQALE
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]