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The map label for this gene is iorA [H]

Identifier: 157370732

GI number: 157370732

Start: 2736011

End: 2736484

Strand: Reverse

Name: iorA [H]

Synonym: Spro_2492

Alternate gene names: 157370732

Gene position: 2736484-2736011 (Counterclockwise)

Preceding gene: 157370733

Following gene: 157370731

Centisome position: 50.22

GC content: 56.54

Gene sequence:

>474_bases
ATGGAAATCAAAATAAACGGCCGGATGGTCGCGCTTGACGACGTCTCGCCCGAGACGCCTTTACTCTACGTGTTACGCAA
CGATCTTGGCCTAAACGGCCCCAAATACGGCTGTGGTTTGGGGGAGTGCGGAGCCTGTACGGTGCTGGTCGATGGCGTTG
CTGCTCGTTCTTGTTCCATTCCTCTGAGCGGTGCGCTCAATAAATCCATTACCACGCTGGAAGGCCTCGGTGAAGCGGGA
CAGCTGCATCCGGTGCAACAAGGCTTTATCGATGAGCAGGCCGCACAGTGCGGTTATTGCACCAACGGCATGATCATGAC
GCTGGTCGCTCTGTTTGAGCGCAATCCGCAGGCCGATGAACAACAAATCAAAAACGAACTGGCCTATAACCTGTGTCGTT
GCGGCACCCATATCGAAATCCTGCGCGCCGCCGCCAAAGCCCGGCAGCTGTTGGCTGAAAGGGGGCAGGCATGA

Upstream 100 bases:

>100_bases
AACATCACTAAGTGTTCTAATGATTATAATTAGCAGGCTGTGAATCATTCACCGCAGTGATATTACGGAGAAATCCGTTT
AGTTAAGGATATATTTCACC

Downstream 100 bases:

>100_bases
GCCGTCTGGAAATAACCCGCCGCCGCCTGTTACAGGCCGGTGGCGTGGTGATGGTCAGCAGCCTGTTGCCGGTTTCGCTT
AATACCCTTGCCGCCGAGCC

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MEIKINGRMVALDDVSPETPLLYVLRNDLGLNGPKYGCGLGECGACTVLVDGVAARSCSIPLSGALNKSITTLEGLGEAG
QLHPVQQGFIDEQAAQCGYCTNGMIMTLVALFERNPQADEQQIKNELAYNLCRCGTHIEILRAAAKARQLLAERGQA

Sequences:

>Translated_157_residues
MEIKINGRMVALDDVSPETPLLYVLRNDLGLNGPKYGCGLGECGACTVLVDGVAARSCSIPLSGALNKSITTLEGLGEAG
QLHPVQQGFIDEQAAQCGYCTNGMIMTLVALFERNPQADEQQIKNELAYNLCRCGTHIEILRAAAKARQLLAERGQA
>Mature_157_residues
MEIKINGRMVALDDVSPETPLLYVLRNDLGLNGPKYGCGLGECGACTVLVDGVAARSCSIPLSGALNKSITTLEGLGEAG
QLHPVQQGFIDEQAAQCGYCTNGMIMTLVALFERNPQADEQQIKNELAYNLCRCGTHIEILRAAAKARQLLAERGQA

Specific function: Specific towards N-containing N-heterocyclic substrates, including isoquinoline, isoquinolin-5-ol, phthalazine and quinazoline [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=150, Percent_Identity=38, Blast_Score=91, Evalue=4e-19,
Organism=Homo sapiens, GI71773480, Length=150, Percent_Identity=39.3333333333333, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=37.6543209876543, Blast_Score=103, Evalue=5e-24,
Organism=Escherichia coli, GI1789232, Length=136, Percent_Identity=45.5882352941176, Blast_Score=98, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17540638, Length=149, Percent_Identity=38.9261744966443, Blast_Score=116, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI32566215, Length=149, Percent_Identity=38.255033557047, Blast_Score=109, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17539860, Length=149, Percent_Identity=36.9127516778523, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17737937, Length=148, Percent_Identity=35.8108108108108, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24647197, Length=159, Percent_Identity=34.5911949685535, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24647195, Length=159, Percent_Identity=34.5911949685535, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24647201, Length=147, Percent_Identity=32.6530612244898, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24647199, Length=150, Percent_Identity=32, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24647193, Length=155, Percent_Identity=30.9677419354839, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.3.99.16 [H]

Molecular weight: Translated: 16764; Mature: 16764

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
7.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIKINGRMVALDDVSPETPLLYVLRNDLGLNGPKYGCGLGECGACTVLVDGVAARSCSI
CEEEECCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHEECCHHHCCCCC
PLSGALNKSITTLEGLGEAGQLHPVQQGFIDEQAAQCGYCTNGMIMTLVALFERNPQADE
CCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHH
QQIKNELAYNLCRCGTHIEILRAAAKARQLLAERGQA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEIKINGRMVALDDVSPETPLLYVLRNDLGLNGPKYGCGLGECGACTVLVDGVAARSCSI
CEEEECCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHEECCHHHCCCCC
PLSGALNKSITTLEGLGEAGQLHPVQQGFIDEQAAQCGYCTNGMIMTLVALFERNPQADE
CCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHH
QQIKNELAYNLCRCGTHIEILRAAAKARQLLAERGQA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7782304; 8157655 [H]