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The map label for this gene is csd1 [H]

Identifier: 157370733

GI number: 157370733

Start: 2736818

End: 2738635

Strand: Reverse

Name: csd1 [H]

Synonym: Spro_2493

Alternate gene names: 157370733

Gene position: 2738635-2736818 (Counterclockwise)

Preceding gene: 157370734

Following gene: 157370732

Centisome position: 50.26

GC content: 60.34

Gene sequence:

>1818_bases
ATGACTATCCAGACAGTTACAAGTAGTTCATTGCCCCACCAGGCGCAGCCTCCAGCCGGTTTGCCGGACGTCAACGCCTT
GGCCAATTTGGCCAATCAGATCTTCAGTGCCTTGCCTGGACGCGAGATTGGCGCGACGTTGCCGCAGGCTGCCGAGGGTG
AACAGGCTGCGACGGTACTGCCACAGTCCTATGCTCCGGCGCTGGAGCCGACACTGGCCACCGAGGTGCCTGAAACGCCA
ACGTTGTCTGGCCGCCAGCAGCGCGTGCAGCGACAGGCTTTTCTGGCACCGCCCACGCTGCCTCAACCGCAGGGGCCGGT
GGCGAGCGCCGGCTTCTATTTTTTGAAAGAAAACCAGCGTCAGCCGTCGGAGGCGGGGTTAGACCGCCTGGCGAACCAGG
CGCTCACCGGTCAAGACTCGCTTAGCGATCAACCCTTTGCGGGGGCGATCAATGGCGGGCTGGAGGCGGTGATTGGCTCG
CTGTTTCCGGCTGTCCCACTACCGGTTCATGGTGTTGCGCAGGATAATGCCAGCGGAAACTACTATTTTCTGGAGCAGGG
GCGGCCCGGGCGCGAAGCAACGCCGCAACAGCAACCGCGCAGCAGTTTTGATGTCCACGCCGTACGTCGCGATTTCCCCA
TCCTTGCGGAGCGGGTCAACGGCAAACCCCTGGTGTGGCTGGATAACGCGGCGACAACTCATAAGCCGCAGGTGGTGATC
GATCGGCTGGCGTATTTTTATGCGCATGAGAACTCGAATATCCACCGTGCGGCGCATGAACTGGCTGCCAGGGCTACCGA
TGCCTATGAGGGGGCCAGAAACAGCGTAGCCCGTTTTCTCGGGGCCAAGTCGGCGGCGGAAATCATCTTTACCCGTGGCG
CGACGGAGGCCATCAATCTGATTGCCAATACCTTTGGTCGTCAGCACATTGGCGAAGGCGATGAGATCGTGGTTTCCCAG
TTGGAACACCACGCCAACATCGTGCCCTGGCAGCAGCTCGCCGCCAGCGTGGGAGCGAAAATTCGGGTGATCCCGGTGGA
CGATAGCGGGCAAATTCTGTTGGCAGAATACCGCAAACTGTTGTCATCGCGTACCCGTCTGGTTTCCATTACCCAGGTGT
CCAACGCGTTGGGCACGGTGACCCCGGTGGAGGAGGTGATTGCGTTGGCGCATCAGGTTGGCGCGCGGGTGCTGGTCGAT
GGGGCGCAGGCGGTCTCGCACCTGAAGGTCAATGTGCAGGCGCTGGACGCGGATTTTTACGTGTTCTCAGGCCACAAGGT
GTTTGGCCCAACGGGTATTGGTGCGGTGTACGGTAAGGCAGAGCTGCTGGACACTCTGCCACCGTGGCAGGGGGGCGGTA
ATATGATTGCCGACGTCACCTTTGAAAAAACGCTGTATCAGCCGGCACCGGCTCGGTTTGAGGCGGGAACCGGTAACATC
GCCGATGCGGTGGGGCTGGGGGCGGCGCTGGACTATGTCGAACGTCTGGGGCTGGACAATATCAATCGTTACGAGCATGA
GTTACTGCAGTATGCCACCGATCGGTTGGTTCGTATTCCCGGCCTGCGTCTGATTGGCACCGCAGCCAATAAGGCCAGCG
TGCTGTCGTTCGTGCTGAGCGGTTATCGTACCGAGGAGGTGGGGAATGCGCTAAACCATGAAGGTATTGCGGTGCGCTCC
GGTCATCACTGTGCGCAGCCGATCCTGCGGCGCTTTGGCGTTGAGGCCACGGTGCGGCCTTCACTGGCGTTTTACAATAC
TTACGAAGAAGTGGATCTGCTGGCAGCGACCTTGCACAAGCTGGCCAAAGGGCGCTAA

Upstream 100 bases:

>100_bases
AATGCGATCGCCTCCTACCTGATCTCACTTTATTGCTCATTGGCGGTTCTGACCGAAGATGCCGTTGCCGTTTTAGACGA
TGTTGATGTGAGCAAATATC

Downstream 100 bases:

>100_bases
CAGTTCCCCGAGGCTAATGACAAGGCTGCCTTTGATTCCGAGATACCCGGGCCTGGCGCACCGAGGGGCGCTCATGGACT
TTCTCGGCAGTCTGAGCGCT

Product: SufS subfamily cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 604

Protein sequence:

>605_residues
MTIQTVTSSSLPHQAQPPAGLPDVNALANLANQIFSALPGREIGATLPQAAEGEQAATVLPQSYAPALEPTLATEVPETP
TLSGRQQRVQRQAFLAPPTLPQPQGPVASAGFYFLKENQRQPSEAGLDRLANQALTGQDSLSDQPFAGAINGGLEAVIGS
LFPAVPLPVHGVAQDNASGNYYFLEQGRPGREATPQQQPRSSFDVHAVRRDFPILAERVNGKPLVWLDNAATTHKPQVVI
DRLAYFYAHENSNIHRAAHELAARATDAYEGARNSVARFLGAKSAAEIIFTRGATEAINLIANTFGRQHIGEGDEIVVSQ
LEHHANIVPWQQLAASVGAKIRVIPVDDSGQILLAEYRKLLSSRTRLVSITQVSNALGTVTPVEEVIALAHQVGARVLVD
GAQAVSHLKVNVQALDADFYVFSGHKVFGPTGIGAVYGKAELLDTLPPWQGGGNMIADVTFEKTLYQPAPARFEAGTGNI
ADAVGLGAALDYVERLGLDNINRYEHELLQYATDRLVRIPGLRLIGTAANKASVLSFVLSGYRTEEVGNALNHEGIAVRS
GHHCAQPILRRFGVEATVRPSLAFYNTYEEVDLLAATLHKLAKGR

Sequences:

>Translated_605_residues
MTIQTVTSSSLPHQAQPPAGLPDVNALANLANQIFSALPGREIGATLPQAAEGEQAATVLPQSYAPALEPTLATEVPETP
TLSGRQQRVQRQAFLAPPTLPQPQGPVASAGFYFLKENQRQPSEAGLDRLANQALTGQDSLSDQPFAGAINGGLEAVIGS
LFPAVPLPVHGVAQDNASGNYYFLEQGRPGREATPQQQPRSSFDVHAVRRDFPILAERVNGKPLVWLDNAATTHKPQVVI
DRLAYFYAHENSNIHRAAHELAARATDAYEGARNSVARFLGAKSAAEIIFTRGATEAINLIANTFGRQHIGEGDEIVVSQ
LEHHANIVPWQQLAASVGAKIRVIPVDDSGQILLAEYRKLLSSRTRLVSITQVSNALGTVTPVEEVIALAHQVGARVLVD
GAQAVSHLKVNVQALDADFYVFSGHKVFGPTGIGAVYGKAELLDTLPPWQGGGNMIADVTFEKTLYQPAPARFEAGTGNI
ADAVGLGAALDYVERLGLDNINRYEHELLQYATDRLVRIPGLRLIGTAANKASVLSFVLSGYRTEEVGNALNHEGIAVRS
GHHCAQPILRRFGVEATVRPSLAFYNTYEEVDLLAATLHKLAKGR
>Mature_604_residues
TIQTVTSSSLPHQAQPPAGLPDVNALANLANQIFSALPGREIGATLPQAAEGEQAATVLPQSYAPALEPTLATEVPETPT
LSGRQQRVQRQAFLAPPTLPQPQGPVASAGFYFLKENQRQPSEAGLDRLANQALTGQDSLSDQPFAGAINGGLEAVIGSL
FPAVPLPVHGVAQDNASGNYYFLEQGRPGREATPQQQPRSSFDVHAVRRDFPILAERVNGKPLVWLDNAATTHKPQVVID
RLAYFYAHENSNIHRAAHELAARATDAYEGARNSVARFLGAKSAAEIIFTRGATEAINLIANTFGRQHIGEGDEIVVSQL
EHHANIVPWQQLAASVGAKIRVIPVDDSGQILLAEYRKLLSSRTRLVSITQVSNALGTVTPVEEVIALAHQVGARVLVDG
AQAVSHLKVNVQALDADFYVFSGHKVFGPTGIGAVYGKAELLDTLPPWQGGGNMIADVTFEKTLYQPAPARFEAGTGNIA
DAVGLGAALDYVERLGLDNINRYEHELLQYATDRLVRIPGLRLIGTAANKASVLSFVLSGYRTEEVGNALNHEGIAVRSG
HHCAQPILRRFGVEATVRPSLAFYNTYEEVDLLAATLHKLAKGR

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=388, Percent_Identity=26.5463917525773, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI156713448, Length=435, Percent_Identity=27.5862068965517, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1787970, Length=402, Percent_Identity=52.2388059701493, Blast_Score=423, Evalue=1e-119,
Organism=Escherichia coli, GI1789175, Length=392, Percent_Identity=40.3061224489796, Blast_Score=303, Evalue=3e-83,
Organism=Escherichia coli, GI48994898, Length=395, Percent_Identity=27.3417721518987, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI25143064, Length=382, Percent_Identity=25.130890052356, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193211090, Length=342, Percent_Identity=26.3157894736842, Blast_Score=84, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319831, Length=229, Percent_Identity=31.0043668122271, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI20129463, Length=404, Percent_Identity=29.9504950495049, Blast_Score=132, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 64860; Mature: 64729

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQTVTSSSLPHQAQPPAGLPDVNALANLANQIFSALPGREIGATLPQAAEGEQAATVL
CEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHC
PQSYAPALEPTLATEVPETPTLSGRQQRVQRQAFLAPPTLPQPQGPVASAGFYFLKENQR
CCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCC
QPSEAGLDRLANQALTGQDSLSDQPFAGAINGGLEAVIGSLFPAVPLPVHGVAQDNASGN
CCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
YYFLEQGRPGREATPQQQPRSSFDVHAVRRDFPILAERVNGKPLVWLDNAATTHKPQVVI
EEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCHHHHH
DRLAYFYAHENSNIHRAAHELAARATDAYEGARNSVARFLGAKSAAEIIFTRGATEAINL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCHHHHHH
IANTFGRQHIGEGDEIVVSQLEHHANIVPWQQLAASVGAKIRVIPVDDSGQILLAEYRKL
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEEECCCCCEEHHHHHHH
LSSRTRLVSITQVSNALGTVTPVEEVIALAHQVGARVLVDGAQAVSHLKVNVQALDADFY
HHCCHHEEEHHHHHHHHCCCCCHHHHHHHHHHHCCEEEECHHHHHHHHEEEEEEECCEEE
VFSGHKVFGPTGIGAVYGKAELLDTLPPWQGGGNMIADVTFEKTLYQPAPARFEAGTGNI
EEECCEEECCCCCHHHHCHHHHHHCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCCCCCCH
ADAVGLGAALDYVERLGLDNINRYEHELLQYATDRLVRIPGLRLIGTAANKASVLSFVLS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHH
GYRTEEVGNALNHEGIAVRSGHHCAQPILRRFGVEATVRPSLAFYNTYEEVDLLAATLHK
CCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCEEECCCCHHHCCHHHHHHHHHHHHH
LAKGR
HHCCC
>Mature Secondary Structure 
TIQTVTSSSLPHQAQPPAGLPDVNALANLANQIFSALPGREIGATLPQAAEGEQAATVL
EEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHC
PQSYAPALEPTLATEVPETPTLSGRQQRVQRQAFLAPPTLPQPQGPVASAGFYFLKENQR
CCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCC
QPSEAGLDRLANQALTGQDSLSDQPFAGAINGGLEAVIGSLFPAVPLPVHGVAQDNASGN
CCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
YYFLEQGRPGREATPQQQPRSSFDVHAVRRDFPILAERVNGKPLVWLDNAATTHKPQVVI
EEEEECCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHCCCCEEEEECCCCCCCCHHHHH
DRLAYFYAHENSNIHRAAHELAARATDAYEGARNSVARFLGAKSAAEIIFTRGATEAINL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEECCCHHHHHH
IANTFGRQHIGEGDEIVVSQLEHHANIVPWQQLAASVGAKIRVIPVDDSGQILLAEYRKL
HHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCEEEEEEECCCCCEEHHHHHHH
LSSRTRLVSITQVSNALGTVTPVEEVIALAHQVGARVLVDGAQAVSHLKVNVQALDADFY
HHCCHHEEEHHHHHHHHCCCCCHHHHHHHHHHHCCEEEECHHHHHHHHEEEEEEECCEEE
VFSGHKVFGPTGIGAVYGKAELLDTLPPWQGGGNMIADVTFEKTLYQPAPARFEAGTGNI
EEECCEEECCCCCHHHHCHHHHHHCCCCCCCCCCEEEEEEHHHHHCCCCCCCCCCCCCCH
ADAVGLGAALDYVERLGLDNINRYEHELLQYATDRLVRIPGLRLIGTAANKASVLSFVLS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHH
GYRTEEVGNALNHEGIAVRSGHHCAQPILRRFGVEATVRPSLAFYNTYEEVDLLAATLHK
CCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHCCCEEECCCCHHHCCHHHHHHHHHHHHH
LAKGR
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]