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The map label for this gene is xdhD [C]

Identifier: 157370731

GI number: 157370731

Start: 2733729

End: 2736014

Strand: Reverse

Name: xdhD [C]

Synonym: Spro_2491

Alternate gene names: 157370731

Gene position: 2736014-2733729 (Counterclockwise)

Preceding gene: 157370732

Following gene: 157370730

Centisome position: 50.21

GC content: 60.28

Gene sequence:

>2286_bases
ATGAGCCGTCTGGAAATAACCCGCCGCCGCCTGTTACAGGCCGGTGGCGTGGTGATGGTCAGCAGCCTGTTGCCGGTTTC
GCTTAATACCCTTGCCGCCGAGCCTGCCACCCTGGGGAACCTGCCGCTGGATCGCGTGGACAGTTTTATCGGTCTGACCG
CCGACGGCCGGGTCACCGCCTTTAACGGCCATGTGGATCTCGGTACTGGCATTCGCACGGCGTTGGCGCAAATTGTTGCC
GATGAAATCTGCGTCCCTTTTGATCAGGTGACGGTCATTCTGGGGGATACCCAGCGCACGCCGGATCAGGGGCCGACCAT
CGCCAGTGCCACCATTCAGGTGACTTCAATACCGCTGCGTCAGGCGGCGGCACAGGTGCGGCAATTGCTGCTGGGGCTGG
CCGCTCGCGCTTTCGCGTTGCCGGTAGACAGGCTGCGTGCAGAAAATGGCCGGGTATTTGCAGCGGATAAACCCCATGTC
AGCCTGAGTTATGGCGATCTGGCCAGAGGGCAAAACTTACAGGTGGCACTGGATAAAACGGTCATGTTGAAGAGCGTGAC
GGAGAGTCGTTACGTTGGCAAGGCGGTGCCACGGGTGGATATCCCGGCCAAGGTCACCGGCCAACTGACCTATGTGCACG
ATCTTCGCCTGCCGGGCATGCTGCACGGCAGAGTGGTGCGGCCGCCTTATATCGGGGCTGACAGCAGTGCCCCGCTGGGC
AGTGGGCTGCTGTCGGTGGACAGAGCTTCCATTGCTCATTTGCCAGGTATCGTAAAGCTGGTGGTGATTAACGATTTTAT
CGGCATCGTCGCCGAGCGTGAAGAGCAGGCGATCGCAGCCATGCGGCAGCTGAAAACCGTGTGGCGCCCGTGGTCCGGGC
TGCCGGATCTCTCGGCGGATGGGCTGCATGCGGCGTTGGTGGCTAACCCGAAAACCGACCGCGTACTGCGTGATGATGCC
GGGGTCGATGCCGCGCTGGGGTCGTTACATACCGAGGTTAATGCCGATTACGTCTGGCCCTATCATCAGCATGCTTCCAT
CGGGCCTTCCTGTGCGGTGGCCGACGTCAGCAGTGAGCATGCAGAAATTTGGTCCGGGACGCAAAACCCTCACGATCTGC
GTAAAGACATTGCCCATTTGCTCGACCGGCAGCCGGAGCAGGTACACATCAACCGTATGGAGGCCTCAGGTTGCTATGGC
CGCAACTGCGCCGATGACGTATCGGCAGATGCCGCACTGTTATCACAGGCGACCGGCAAACCGGTCAGGGTGCAGTTGAT
GCGCGAGCAAGAGTCGGGCTGGGAGCCCAAGGGCACCGGGCAGTTGATCCGGGTGCGCGGTGGGCTGGATCAGCACCGGC
AGGTGGCGGCCTATGAGTTGAAAACCAGTTATCCTTCCAATAATGCCGTGACATTGTCACTGGTGTTGGCCGGCAAGGTG
GCCAATCGGGCCGACGTACAGCAGATGGGCGACAGAACCGCCATTCCGCAGTATGAATATCCGAACATGCGGGTGATTTG
CCAGGACGCTGCGCCGATCGTTCGGGCTTCCTGGATGCGCGGGGTGTCGGCGCTGCCCAACGTGTTCGCCCATGAGTCGT
GGATTGATGAACTGGCATGGCATGCCGGGCAGGATCCGATCGCTTTCCGCCTGCAATATCTGAAAGACCCGCGTGCGGTC
GCGTTGATCAATGCGCTGAAGAAACAGGCTAACTGGCAGCAGGGGCCGTCGCATCGCAACCCGGCACCGGATACGCAAGC
GTGGGTCAGTGGACGTGGCTTTGCTTATGCGCGTTACTTCCACAGCAAATTCCCCGGTTTCGGCGCCGCCTGGGCTGCCT
GGGTGTGTGACCTTAGCGTCAATCGCCACAGCGGTCAGATCAAGCTCGATAAAATCTTTGTTGCCCATGACTGCGGACGC
ATCATCAACCCGGCCGGAGTGCGCCATCAGGTGCATGGCAATATTCTTCAGTCCGCCAGCCGGGTGCTGAAAGAGTTTGT
CACCTTTGACGCTTCGGCGGTGACGTCGCTGGACTGGGGCGGCTACCCGATCCTGCGTTTTGACGAGTTGCCGCAGGTGG
ATGTTCAATTGCTGGACTATCCGGATGAGCCGCCGATGGGGGCGGGAGAATCGGCTTCGGTGCCGAGTGCGGCCGCTATC
GCCAATGCGTTATTTGATGCGCTGGGGGTGCGCCTGCGGGAAGTGCCATTTACTCCCGAGCAGGTGCTGAAAGCGTTAAA
ACAGCAGGCTTCCGCCAACGCAGCAACCAGGGATAAGTCATTATGA

Upstream 100 bases:

>100_bases
AAAACGAACTGGCCTATAACCTGTGTCGTTGCGGCACCCATATCGAAATCCTGCGCGCCGCCGCCAAAGCCCGGCAGCTG
TTGGCTGAAAGGGGGCAGGC

Downstream 100 bases:

>100_bases
GCAAATTAAAGAAAGCCGCTGGATGGGGCAGCCTGGCCGTCATCGCCGTAGCAGTCACCGGCGCTATTATCAGCTGGCAG
CCGGAAATTTCGCCTCGTGA

Product: aldehyde oxidase and xanthine dehydrogenase

Products: NA

Alternate protein names: ALDH [H]

Number of amino acids: Translated: 761; Mature: 760

Protein sequence:

>761_residues
MSRLEITRRRLLQAGGVVMVSSLLPVSLNTLAAEPATLGNLPLDRVDSFIGLTADGRVTAFNGHVDLGTGIRTALAQIVA
DEICVPFDQVTVILGDTQRTPDQGPTIASATIQVTSIPLRQAAAQVRQLLLGLAARAFALPVDRLRAENGRVFAADKPHV
SLSYGDLARGQNLQVALDKTVMLKSVTESRYVGKAVPRVDIPAKVTGQLTYVHDLRLPGMLHGRVVRPPYIGADSSAPLG
SGLLSVDRASIAHLPGIVKLVVINDFIGIVAEREEQAIAAMRQLKTVWRPWSGLPDLSADGLHAALVANPKTDRVLRDDA
GVDAALGSLHTEVNADYVWPYHQHASIGPSCAVADVSSEHAEIWSGTQNPHDLRKDIAHLLDRQPEQVHINRMEASGCYG
RNCADDVSADAALLSQATGKPVRVQLMREQESGWEPKGTGQLIRVRGGLDQHRQVAAYELKTSYPSNNAVTLSLVLAGKV
ANRADVQQMGDRTAIPQYEYPNMRVICQDAAPIVRASWMRGVSALPNVFAHESWIDELAWHAGQDPIAFRLQYLKDPRAV
ALINALKKQANWQQGPSHRNPAPDTQAWVSGRGFAYARYFHSKFPGFGAAWAAWVCDLSVNRHSGQIKLDKIFVAHDCGR
IINPAGVRHQVHGNILQSASRVLKEFVTFDASAVTSLDWGGYPILRFDELPQVDVQLLDYPDEPPMGAGESASVPSAAAI
ANALFDALGVRLREVPFTPEQVLKALKQQASANAATRDKSL

Sequences:

>Translated_761_residues
MSRLEITRRRLLQAGGVVMVSSLLPVSLNTLAAEPATLGNLPLDRVDSFIGLTADGRVTAFNGHVDLGTGIRTALAQIVA
DEICVPFDQVTVILGDTQRTPDQGPTIASATIQVTSIPLRQAAAQVRQLLLGLAARAFALPVDRLRAENGRVFAADKPHV
SLSYGDLARGQNLQVALDKTVMLKSVTESRYVGKAVPRVDIPAKVTGQLTYVHDLRLPGMLHGRVVRPPYIGADSSAPLG
SGLLSVDRASIAHLPGIVKLVVINDFIGIVAEREEQAIAAMRQLKTVWRPWSGLPDLSADGLHAALVANPKTDRVLRDDA
GVDAALGSLHTEVNADYVWPYHQHASIGPSCAVADVSSEHAEIWSGTQNPHDLRKDIAHLLDRQPEQVHINRMEASGCYG
RNCADDVSADAALLSQATGKPVRVQLMREQESGWEPKGTGQLIRVRGGLDQHRQVAAYELKTSYPSNNAVTLSLVLAGKV
ANRADVQQMGDRTAIPQYEYPNMRVICQDAAPIVRASWMRGVSALPNVFAHESWIDELAWHAGQDPIAFRLQYLKDPRAV
ALINALKKQANWQQGPSHRNPAPDTQAWVSGRGFAYARYFHSKFPGFGAAWAAWVCDLSVNRHSGQIKLDKIFVAHDCGR
IINPAGVRHQVHGNILQSASRVLKEFVTFDASAVTSLDWGGYPILRFDELPQVDVQLLDYPDEPPMGAGESASVPSAAAI
ANALFDALGVRLREVPFTPEQVLKALKQQASANAATRDKSL
>Mature_760_residues
SRLEITRRRLLQAGGVVMVSSLLPVSLNTLAAEPATLGNLPLDRVDSFIGLTADGRVTAFNGHVDLGTGIRTALAQIVAD
EICVPFDQVTVILGDTQRTPDQGPTIASATIQVTSIPLRQAAAQVRQLLLGLAARAFALPVDRLRAENGRVFAADKPHVS
LSYGDLARGQNLQVALDKTVMLKSVTESRYVGKAVPRVDIPAKVTGQLTYVHDLRLPGMLHGRVVRPPYIGADSSAPLGS
GLLSVDRASIAHLPGIVKLVVINDFIGIVAEREEQAIAAMRQLKTVWRPWSGLPDLSADGLHAALVANPKTDRVLRDDAG
VDAALGSLHTEVNADYVWPYHQHASIGPSCAVADVSSEHAEIWSGTQNPHDLRKDIAHLLDRQPEQVHINRMEASGCYGR
NCADDVSADAALLSQATGKPVRVQLMREQESGWEPKGTGQLIRVRGGLDQHRQVAAYELKTSYPSNNAVTLSLVLAGKVA
NRADVQQMGDRTAIPQYEYPNMRVICQDAAPIVRASWMRGVSALPNVFAHESWIDELAWHAGQDPIAFRLQYLKDPRAVA
LINALKKQANWQQGPSHRNPAPDTQAWVSGRGFAYARYFHSKFPGFGAAWAAWVCDLSVNRHSGQIKLDKIFVAHDCGRI
INPAGVRHQVHGNILQSASRVLKEFVTFDASAVTSLDWGGYPILRFDELPQVDVQLLDYPDEPPMGAGESASVPSAAAIA
NALFDALGVRLREVPFTPEQVLKALKQQASANAATRDKSL

Specific function: Probably Has No Xanthine Dehydrogenase Activity; However Deletion Results In Increased Adenine Sensitivity, Suggesting That This Protein Contributes To The Conversion Of Adenine To Guanine Nucleotides During Purine Salvage. [C]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789246, Length=151, Percent_Identity=30.4635761589404, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786478, Length=145, Percent_Identity=28.9655172413793, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012368
- InterPro:   IPR006311 [H]

Pfam domain/function: PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.3 [H]

Molecular weight: Translated: 82457; Mature: 82326

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLEITRRRLLQAGGVVMVSSLLPVSLNTLAAEPATLGNLPLDRVDSFIGLTADGRVTA
CCCHHHHHHHHHHHCCCEEEHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHEECCCCEEEE
FNGHVDLGTGIRTALAQIVADEICVPFDQVTVILGDTQRTPDQGPTIASATIQVTSIPLR
EECCEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEEECCHH
QAAAQVRQLLLGLAARAFALPVDRLRAENGRVFAADKPHVSLSYGDLARGQNLQVALDKT
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCCCCEEEECCCCCCCCCEEEEECHH
VMLKSVTESRYVGKAVPRVDIPAKVTGQLTYVHDLRLPGMLHGRVVRPPYIGADSSAPLG
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHCCCEECCCCCCCCCCCCCC
SGLLSVDRASIAHLPGIVKLVVINDFIGIVAEREEQAIAAMRQLKTVWRPWSGLPDLSAD
CCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GLHAALVANPKTDRVLRDDAGVDAALGSLHTEVNADYVWPYHQHASIGPSCAVADVSSEH
CCEEEEEECCCCCCEECCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCEEEECCCCHH
AEIWSGTQNPHDLRKDIAHLLDRQPEQVHINRMEASGCYGRNCADDVSADAALLSQATGK
HHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCC
PVRVQLMREQESGWEPKGTGQLIRVRGGLDQHRQVAAYELKTSYPSNNAVTLSLVLAGKV
CEEEEEEEHHHCCCCCCCCCCEEEEECCCCHHHHEEEEEEECCCCCCCEEEEEEEEECCC
ANRADVQQMGDRTAIPQYEYPNMRVICQDAAPIVRASWMRGVSALPNVFAHESWIDELAW
CCHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAGQDPIAFRLQYLKDPRAVALINALKKQANWQQGPSHRNPAPDTQAWVSGRGFAYARYF
HCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCEEHHHH
HSKFPGFGAAWAAWVCDLSVNRHSGQIKLDKIFVAHDCGRIINPAGVRHQVHGNILQSAS
HHCCCCCCHHHHHHHEECEECCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
RVLKEFVTFDASAVTSLDWGGYPILRFDELPQVDVQLLDYPDEPPMGAGESASVPSAAAI
HHHHHHHHCCCHHHEECCCCCCCEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHH
ANALFDALGVRLREVPFTPEQVLKALKQQASANAATRDKSL
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SRLEITRRRLLQAGGVVMVSSLLPVSLNTLAAEPATLGNLPLDRVDSFIGLTADGRVTA
CCHHHHHHHHHHHCCCEEEHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHEECCCCEEEE
FNGHVDLGTGIRTALAQIVADEICVPFDQVTVILGDTQRTPDQGPTIASATIQVTSIPLR
EECCEECCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEEECCHH
QAAAQVRQLLLGLAARAFALPVDRLRAENGRVFAADKPHVSLSYGDLARGQNLQVALDKT
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCEEEECCCCCEEEECCCCCCCCCEEEEECHH
VMLKSVTESRYVGKAVPRVDIPAKVTGQLTYVHDLRLPGMLHGRVVRPPYIGADSSAPLG
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCCHHCCCEECCCCCCCCCCCCCC
SGLLSVDRASIAHLPGIVKLVVINDFIGIVAEREEQAIAAMRQLKTVWRPWSGLPDLSAD
CCHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GLHAALVANPKTDRVLRDDAGVDAALGSLHTEVNADYVWPYHQHASIGPSCAVADVSSEH
CCEEEEEECCCCCCEECCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCEEEECCCCHH
AEIWSGTQNPHDLRKDIAHLLDRQPEQVHINRMEASGCYGRNCADDVSADAALLSQATGK
HHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCC
PVRVQLMREQESGWEPKGTGQLIRVRGGLDQHRQVAAYELKTSYPSNNAVTLSLVLAGKV
CEEEEEEEHHHCCCCCCCCCCEEEEECCCCHHHHEEEEEEECCCCCCCEEEEEEEEECCC
ANRADVQQMGDRTAIPQYEYPNMRVICQDAAPIVRASWMRGVSALPNVFAHESWIDELAW
CCHHHHHHHCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HAGQDPIAFRLQYLKDPRAVALINALKKQANWQQGPSHRNPAPDTQAWVSGRGFAYARYF
HCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCEEHHHH
HSKFPGFGAAWAAWVCDLSVNRHSGQIKLDKIFVAHDCGRIINPAGVRHQVHGNILQSAS
HHCCCCCCHHHHHHHEECEECCCCCEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
RVLKEFVTFDASAVTSLDWGGYPILRFDELPQVDVQLLDYPDEPPMGAGESASVPSAAAI
HHHHHHHHCCCHHHEECCCCCCCEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHH
ANALFDALGVRLREVPFTPEQVLKALKQQASANAATRDKSL
HHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2606906 [H]