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The map label for this gene is acrF [H]

Identifier: 157370718

GI number: 157370718

Start: 2715975

End: 2719130

Strand: Reverse

Name: acrF [H]

Synonym: Spro_2478

Alternate gene names: 157370718

Gene position: 2719130-2715975 (Counterclockwise)

Preceding gene: 157370719

Following gene: 157370717

Centisome position: 49.9

GC content: 57.54

Gene sequence:

>3156_bases
ATGGCGCAGTTCTTTATTCGGCGGCCGGTGTTTGCCTGGGTGATTGCGATCATCATCATGCTGTGTGGCCTGATGTCGAT
CAATTCGCTCCCCATCTCGCAATATCCGGACGTCTCCCCACCGCAGATTTCCATTTCCGCCACCTACCCGGGGGCCGATG
CGGAAACTCTGGAAAACAGCGTTACCCAGGTGATTGAGCAGCAGCTTACCGGCCTGGACGGACTGCTTTATTTTTCTGCT
ACCAGCAGCTCCGACGGTTCGGTGAGCATTAACGTGACCTTTGATCAGGGCACGGATCCGGATATCGCTCAGGTGCAGGT
GCAAAACAAGGTGCAGCAGGCGGAAAGCCGTCTGCCGGCCGAGGTGACCGCTCAAGGGGTCACGGTCAAGAAATCCCAGA
GCAGTTTTTTGCTGATCGTCGGGCTGTATGATGAAACCGACAAGGCCAGCATGGCGGATATTTCCGACTATCTGGTGAGC
AACATTCAGGATCCGCTGTCGCGCATAGACGGCGTCGGTGATGTGCAGGTATTCGGGTCAGAATACGCGATGCGCATCTG
GCTTAACCCGACCAAAATGGCGTCTTTTTCACTGATGCCGTCCGATGTGGAAACGGCGATTGAGGCGCAAAACACCCAGG
TTTCTGCCGGTAAGGTCGGCGATTTGCCTTCCGGTGCCGATCAGCAACTGACCGCCACGGTGAAGGCGCAGTCGCGGCTG
CAAACGCCGGAGCAGTTCCGCAATATTATCCTGAAAAGCGACAGCAGCGGGGCGTTGGTGCGCCTGGGCGATGTGGCACG
GGTTGAACTGGGCAACGAGGATTACTCCTCCAGTGCCCGCTTGAATGGCCACCCGGCCTCAGGGATTGCCGTCAAGCTGG
CCGCCGGGGCCAATGCGCTCAATACCGCCAAACTGGTCAAGGCCAAGGTGGCGGAATACCAAACCTCAATGCCGCATGGC
TACAAGGTGGCCTATCCGAAAGACAGCACCGACTTTATTAATATCTCGATCGAAGAGGTGGTGAAAACCCTGATCGAGGC
GGTGGTGTTGGTGGTGATCGTGATGTTTGTCTTCCTGCAGAACTTGCGTACCACGCTGATCCCGACCATTACCGTGCCGG
TGGTGCTGTTGGGCACCTTCGGTGTACTCGCCGCCTTCGGCTATTCAATCAACACCCTGACGCTGTTTGGCATGGTACTG
GCTATCGGACTCTTGGTGGATGACGCCATCGTGGTGGTGGAGAACGTCGAACGCGTGATGCGGGAAGAGAAACTGCCGCC
GCGCGAGGCAACCGAAAAATCGATGAAGGAAATCACCGGCGCGCTGGTTGGCATTGCCATGGTGCTGTCGGCGGTCTTCC
TGCCGATGGCGTTTTTCGGCGGTTCCACCGGGGTGATCTACCGCCAGTTCTCGGTCACTATTGTGGCTTCCATGGTGTTG
TCGGTGATCCTGGCGTTGACCCTGGCTCCGGCACTGTGCGCCACCTTGCTGAAACCTGCGCATGAGGAACTGACCAACAA
GGGCCTGCTGGGCAAATTTAACCGCGGCTATAACCGCCTGCAGGAGAAATATGCCGATAAGGTCGGCAGGGTGATCCACA
GCCCAATGCGCTATCTGTTGCTGTATGGCCTGTTGTTGATTGCCGCTGCCGTGATGTATATGCGTTTGCCGACCGGCTTT
CTGCCCAATGAAGATCAGGGGGTGGTGATGGTGCAGTATACGCTGCCTGCCGGTGCCACCAATGCCCGTACCTCGGCGGT
CAGTGACGAAGTAAAAGATTATTTCCTCAACGATGAGAAGGCCAACGTCAGCACCATTTTCACCATTAACGGCTTTGGTT
TCAGCGGCAGTGGACAAAACGCCGGTATGGCCTTCGTCAGCCTGAAAGACTGGAGTTTACGCTCCGGCAGTGCCAATACC
GCTGATGCGATTGCCAAGCGTGCGATGGCGCACTTCGCCAAGATCCGCGATGCCCAGGTGTTCTCGATGAGCCCTCCGGC
GATCGACGGTTTTGGCCAGTCTGACGGTTTCACCTTCGAATTGCAGGCCAAAGGCGCAACGACCCGTGCAGAGTTGCAGG
TGATGCGTGACCAGATAATTGCGGCGGCGGCGAAAAATCCCAGCCTGAGCGCGGTTCGCGCCAACACTCTGCCGGATACG
CCACAGCTGCAGGTGGAGATCGACAATGACAAACTGCAGGCGTTGGGGCTGAGTAATAGCGACGTCAGCAGCACGCTTAC
CAACGCCTTCGGCAGCACCTATATCAACGACTTTATCGACCGCAACCGGGTGAAAAAAGTCTATATGCAGGGTGACGTCG
AGTACCGTTCAAAACCGGAAGATCTCGAAAAATGGTTTGTCCGTGGGACTTCCAGCAGCGGTACCACCAGCATGACGCCG
TTCTCGGCCTTTGCCTCTTCCCACTGGATCTACGGGCCGGAAAACCTGTCGCGCTATAACGGCCTGTCGTCGTTTGAGAT
CACCGGTGAAGGCGCGCCCGGTACCAGTTCCGGTACGGCGATGGATGAGATGGCAAAGCTGGCGGCGAAGTTCTCTTCCG
CCAGCAGCTTTTCCTGGAGCGGTCTGTCTTATCAGGAGCGCTTGACCAGCGGACAGGCTGGGTCCCTGTATGCCATTTCA
CTGGTGGTGGTGTTCCTGTGCCTGGCCGCACTGTATGAGAGCTGGTCAATTCCGTTCGCGGTGATGATGGTGGTGCCGAT
GGGCGTGGTCGGGTCGCTGTTGGCGATCACCCTGCGTGGGCTGGAAAACGATATTTACTTCCAGGTGGCGCTGTTGACCA
TCATTGGGCTGTCGGCCAAGAACGCCATTCTTATCGTCGAATTCGCCGAAGAGAAATACCTGCGGGGCGAAACCTTGATC
GCCGCGGCGGTCGAGGCATCCCGCATGCGTCTGCGCCCGATTCTGATGACCTCCCTGGCGTTTAGCGCCGGCGTGTTACC
GCTGGCGGTGTCCAGCGGTGCCGGGGCCAACAGCCGCATCGCTATCGGTACCGGGATTATTGGCGGCACCATCACGGCAA
CGATACTGGCGATCTTCTTCGTTCCCTTGTTCTACGTCTTGGTGCGCCGGATGTTTTCACGCAAAACCACCGTCGCCAAA
CCGCTGGAAAACACTGCGCCGCAGGCAGGAGAATAA

Upstream 100 bases:

>100_bases
TCGAAGGCACCAGTAAGGTGGCCGTCGGCGTTGAGGTCAAGGCCGTTGAAGTGCAACAGCAGGCGAATAAGGCTGCGACT
AACGGCGGGGATCAATAACC

Downstream 100 bases:

>100_bases
TGTGTTGCAACGTTTAATCACTCTGACATTTCCGCTGTTACTGGCGGGGTGTATCTCGCTGGATCCAAACTACCAGCGCC
CAGCGGCACCGGTTCCCACC

Product: hydrophobe/amphiphile efflux-1 (HAE1) family protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: Protein EnvD [H]

Number of amino acids: Translated: 1051; Mature: 1050

Protein sequence:

>1051_residues
MAQFFIRRPVFAWVIAIIIMLCGLMSINSLPISQYPDVSPPQISISATYPGADAETLENSVTQVIEQQLTGLDGLLYFSA
TSSSDGSVSINVTFDQGTDPDIAQVQVQNKVQQAESRLPAEVTAQGVTVKKSQSSFLLIVGLYDETDKASMADISDYLVS
NIQDPLSRIDGVGDVQVFGSEYAMRIWLNPTKMASFSLMPSDVETAIEAQNTQVSAGKVGDLPSGADQQLTATVKAQSRL
QTPEQFRNIILKSDSSGALVRLGDVARVELGNEDYSSSARLNGHPASGIAVKLAAGANALNTAKLVKAKVAEYQTSMPHG
YKVAYPKDSTDFINISIEEVVKTLIEAVVLVVIVMFVFLQNLRTTLIPTITVPVVLLGTFGVLAAFGYSINTLTLFGMVL
AIGLLVDDAIVVVENVERVMREEKLPPREATEKSMKEITGALVGIAMVLSAVFLPMAFFGGSTGVIYRQFSVTIVASMVL
SVILALTLAPALCATLLKPAHEELTNKGLLGKFNRGYNRLQEKYADKVGRVIHSPMRYLLLYGLLLIAAAVMYMRLPTGF
LPNEDQGVVMVQYTLPAGATNARTSAVSDEVKDYFLNDEKANVSTIFTINGFGFSGSGQNAGMAFVSLKDWSLRSGSANT
ADAIAKRAMAHFAKIRDAQVFSMSPPAIDGFGQSDGFTFELQAKGATTRAELQVMRDQIIAAAAKNPSLSAVRANTLPDT
PQLQVEIDNDKLQALGLSNSDVSSTLTNAFGSTYINDFIDRNRVKKVYMQGDVEYRSKPEDLEKWFVRGTSSSGTTSMTP
FSAFASSHWIYGPENLSRYNGLSSFEITGEGAPGTSSGTAMDEMAKLAAKFSSASSFSWSGLSYQERLTSGQAGSLYAIS
LVVVFLCLAALYESWSIPFAVMMVVPMGVVGSLLAITLRGLENDIYFQVALLTIIGLSAKNAILIVEFAEEKYLRGETLI
AAAVEASRMRLRPILMTSLAFSAGVLPLAVSSGAGANSRIAIGTGIIGGTITATILAIFFVPLFYVLVRRMFSRKTTVAK
PLENTAPQAGE

Sequences:

>Translated_1051_residues
MAQFFIRRPVFAWVIAIIIMLCGLMSINSLPISQYPDVSPPQISISATYPGADAETLENSVTQVIEQQLTGLDGLLYFSA
TSSSDGSVSINVTFDQGTDPDIAQVQVQNKVQQAESRLPAEVTAQGVTVKKSQSSFLLIVGLYDETDKASMADISDYLVS
NIQDPLSRIDGVGDVQVFGSEYAMRIWLNPTKMASFSLMPSDVETAIEAQNTQVSAGKVGDLPSGADQQLTATVKAQSRL
QTPEQFRNIILKSDSSGALVRLGDVARVELGNEDYSSSARLNGHPASGIAVKLAAGANALNTAKLVKAKVAEYQTSMPHG
YKVAYPKDSTDFINISIEEVVKTLIEAVVLVVIVMFVFLQNLRTTLIPTITVPVVLLGTFGVLAAFGYSINTLTLFGMVL
AIGLLVDDAIVVVENVERVMREEKLPPREATEKSMKEITGALVGIAMVLSAVFLPMAFFGGSTGVIYRQFSVTIVASMVL
SVILALTLAPALCATLLKPAHEELTNKGLLGKFNRGYNRLQEKYADKVGRVIHSPMRYLLLYGLLLIAAAVMYMRLPTGF
LPNEDQGVVMVQYTLPAGATNARTSAVSDEVKDYFLNDEKANVSTIFTINGFGFSGSGQNAGMAFVSLKDWSLRSGSANT
ADAIAKRAMAHFAKIRDAQVFSMSPPAIDGFGQSDGFTFELQAKGATTRAELQVMRDQIIAAAAKNPSLSAVRANTLPDT
PQLQVEIDNDKLQALGLSNSDVSSTLTNAFGSTYINDFIDRNRVKKVYMQGDVEYRSKPEDLEKWFVRGTSSSGTTSMTP
FSAFASSHWIYGPENLSRYNGLSSFEITGEGAPGTSSGTAMDEMAKLAAKFSSASSFSWSGLSYQERLTSGQAGSLYAIS
LVVVFLCLAALYESWSIPFAVMMVVPMGVVGSLLAITLRGLENDIYFQVALLTIIGLSAKNAILIVEFAEEKYLRGETLI
AAAVEASRMRLRPILMTSLAFSAGVLPLAVSSGAGANSRIAIGTGIIGGTITATILAIFFVPLFYVLVRRMFSRKTTVAK
PLENTAPQAGE
>Mature_1050_residues
AQFFIRRPVFAWVIAIIIMLCGLMSINSLPISQYPDVSPPQISISATYPGADAETLENSVTQVIEQQLTGLDGLLYFSAT
SSSDGSVSINVTFDQGTDPDIAQVQVQNKVQQAESRLPAEVTAQGVTVKKSQSSFLLIVGLYDETDKASMADISDYLVSN
IQDPLSRIDGVGDVQVFGSEYAMRIWLNPTKMASFSLMPSDVETAIEAQNTQVSAGKVGDLPSGADQQLTATVKAQSRLQ
TPEQFRNIILKSDSSGALVRLGDVARVELGNEDYSSSARLNGHPASGIAVKLAAGANALNTAKLVKAKVAEYQTSMPHGY
KVAYPKDSTDFINISIEEVVKTLIEAVVLVVIVMFVFLQNLRTTLIPTITVPVVLLGTFGVLAAFGYSINTLTLFGMVLA
IGLLVDDAIVVVENVERVMREEKLPPREATEKSMKEITGALVGIAMVLSAVFLPMAFFGGSTGVIYRQFSVTIVASMVLS
VILALTLAPALCATLLKPAHEELTNKGLLGKFNRGYNRLQEKYADKVGRVIHSPMRYLLLYGLLLIAAAVMYMRLPTGFL
PNEDQGVVMVQYTLPAGATNARTSAVSDEVKDYFLNDEKANVSTIFTINGFGFSGSGQNAGMAFVSLKDWSLRSGSANTA
DAIAKRAMAHFAKIRDAQVFSMSPPAIDGFGQSDGFTFELQAKGATTRAELQVMRDQIIAAAAKNPSLSAVRANTLPDTP
QLQVEIDNDKLQALGLSNSDVSSTLTNAFGSTYINDFIDRNRVKKVYMQGDVEYRSKPEDLEKWFVRGTSSSGTTSMTPF
SAFASSHWIYGPENLSRYNGLSSFEITGEGAPGTSSGTAMDEMAKLAAKFSSASSFSWSGLSYQERLTSGQAGSLYAISL
VVVFLCLAALYESWSIPFAVMMVVPMGVVGSLLAITLRGLENDIYFQVALLTIIGLSAKNAILIVEFAEEKYLRGETLIA
AAVEASRMRLRPILMTSLAFSAGVLPLAVSSGAGANSRIAIGTGIIGGTITATILAIFFVPLFYVLVRRMFSRKTTVAKP
LENTAPQAGE

Specific function: Involved in cell envelope formation. Is produced in extremely low amounts [H]

COG id: COG0841

COG function: function code V; Cation/multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family [H]

Homologues:

Organism=Escherichia coli, GI1789666, Length=1036, Percent_Identity=58.2046332046332, Blast_Score=1223, Evalue=0.0,
Organism=Escherichia coli, GI1786667, Length=1024, Percent_Identity=58.203125, Blast_Score=1222, Evalue=0.0,
Organism=Escherichia coli, GI1788814, Length=1039, Percent_Identity=55.9191530317613, Blast_Score=1189, Evalue=0.0,
Organism=Escherichia coli, GI1789930, Length=1037, Percent_Identity=55.8341369334619, Blast_Score=1144, Evalue=0.0,
Organism=Escherichia coli, GI1788391, Length=1050, Percent_Identity=31.047619047619, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1788390, Length=1043, Percent_Identity=29.1466922339406, Blast_Score=384, Evalue=1e-107,
Organism=Escherichia coli, GI1786788, Length=1090, Percent_Identity=23.2110091743119, Blast_Score=221, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR004764 [H]

Pfam domain/function: PF00873 ACR_tran [H]

EC number: NA

Molecular weight: Translated: 112832; Mature: 112701

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQFFIRRPVFAWVIAIIIMLCGLMSINSLPISQYPDVSPPQISISATYPGADAETLENS
CCCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
VTQVIEQQLTGLDGLLYFSATSSSDGSVSINVTFDQGTDPDIAQVQVQNKVQQAESRLPA
HHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCH
EVTAQGVTVKKSQSSFLLIVGLYDETDKASMADISDYLVSNIQDPLSRIDGVGDVQVFGS
HHHCCCEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
EYAMRIWLNPTKMASFSLMPSDVETAIEAQNTQVSAGKVGDLPSGADQQLTATVKAQSRL
CEEEEEEECCHHHCEEECCCCHHHHHHHHCCCEECCCCCCCCCCCCCCHHEEHHHHHHHC
QTPEQFRNIILKSDSSGALVRLGDVARVELGNEDYSSSARLNGHPASGIAVKLAAGANAL
CCHHHHHHHEEECCCCCCEEEECCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCH
NTAKLVKAKVAEYQTSMPHGYKVAYPKDSTDFINISIEEVVKTLIEAVVLVVIVMFVFLQ
HHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
NLRTTLIPTITVPVVLLGTFGVLAAFGYSINTLTLFGMVLAIGLLVDDAIVVVENVERVM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REEKLPPREATEKSMKEITGALVGIAMVLSAVFLPMAFFGGSTGVIYRQFSVTIVASMVL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
SVILALTLAPALCATLLKPAHEELTNKGLLGKFNRGYNRLQEKYADKVGRVIHSPMRYLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGLLLIAAAVMYMRLPTGFLPNEDQGVVMVQYTLPAGATNARTSAVSDEVKDYFLNDEK
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCC
ANVSTIFTINGFGFSGSGQNAGMAFVSLKDWSLRSGSANTADAIAKRAMAHFAKIRDAQV
CCEEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
FSMSPPAIDGFGQSDGFTFELQAKGATTRAELQVMRDQIIAAAAKNPSLSAVRANTLPDT
EECCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
PQLQVEIDNDKLQALGLSNSDVSSTLTNAFGSTYINDFIDRNRVKKVYMQGDVEYRSKPE
CCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEHEECCCCCCCCHH
DLEKWFVRGTSSSGTTSMTPFSAFASSHWIYGPENLSRYNGLSSFEITGEGAPGTSSGTA
HHHHHHHCCCCCCCCCCCCCHHHHHCCCCEECCCHHHHHCCCCEEEEECCCCCCCCCCCH
MDEMAKLAAKFSSASSFSWSGLSYQERLTSGQAGSLYAISLVVVFLCLAALYESWSIPFA
HHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
VMMVVPMGVVGSLLAITLRGLENDIYFQVALLTIIGLSAKNAILIVEFAEEKYLRGETLI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHCCCHHH
AAAVEASRMRLRPILMTSLAFSAGVLPLAVSSGAGANSRIAIGTGIIGGTITATILAIFF
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHH
VPLFYVLVRRMFSRKTTVAKPLENTAPQAGE
HHHHHHHHHHHHHCCHHHHCCHHHCCCCCCC
>Mature Secondary Structure 
AQFFIRRPVFAWVIAIIIMLCGLMSINSLPISQYPDVSPPQISISATYPGADAETLENS
CCHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
VTQVIEQQLTGLDGLLYFSATSSSDGSVSINVTFDQGTDPDIAQVQVQNKVQQAESRLPA
HHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCH
EVTAQGVTVKKSQSSFLLIVGLYDETDKASMADISDYLVSNIQDPLSRIDGVGDVQVFGS
HHHCCCEEEEECCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
EYAMRIWLNPTKMASFSLMPSDVETAIEAQNTQVSAGKVGDLPSGADQQLTATVKAQSRL
CEEEEEEECCHHHCEEECCCCHHHHHHHHCCCEECCCCCCCCCCCCCCHHEEHHHHHHHC
QTPEQFRNIILKSDSSGALVRLGDVARVELGNEDYSSSARLNGHPASGIAVKLAAGANAL
CCHHHHHHHEEECCCCCCEEEECCEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCH
NTAKLVKAKVAEYQTSMPHGYKVAYPKDSTDFINISIEEVVKTLIEAVVLVVIVMFVFLQ
HHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
NLRTTLIPTITVPVVLLGTFGVLAAFGYSINTLTLFGMVLAIGLLVDDAIVVVENVERVM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REEKLPPREATEKSMKEITGALVGIAMVLSAVFLPMAFFGGSTGVIYRQFSVTIVASMVL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHH
SVILALTLAPALCATLLKPAHEELTNKGLLGKFNRGYNRLQEKYADKVGRVIHSPMRYLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYGLLLIAAAVMYMRLPTGFLPNEDQGVVMVQYTLPAGATNARTSAVSDEVKDYFLNDEK
HHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCC
ANVSTIFTINGFGFSGSGQNAGMAFVSLKDWSLRSGSANTADAIAKRAMAHFAKIRDAQV
CCEEEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
FSMSPPAIDGFGQSDGFTFELQAKGATTRAELQVMRDQIIAAAAKNPSLSAVRANTLPDT
EECCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCC
PQLQVEIDNDKLQALGLSNSDVSSTLTNAFGSTYINDFIDRNRVKKVYMQGDVEYRSKPE
CCEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEHEECCCCCCCCHH
DLEKWFVRGTSSSGTTSMTPFSAFASSHWIYGPENLSRYNGLSSFEITGEGAPGTSSGTA
HHHHHHHCCCCCCCCCCCCCHHHHHCCCCEECCCHHHHHCCCCEEEEECCCCCCCCCCCH
MDEMAKLAAKFSSASSFSWSGLSYQERLTSGQAGSLYAISLVVVFLCLAALYESWSIPFA
HHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
VMMVVPMGVVGSLLAITLRGLENDIYFQVALLTIIGLSAKNAILIVEFAEEKYLRGETLI
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHCCCHHH
AAAVEASRMRLRPILMTSLAFSAGVLPLAVSSGAGANSRIAIGTGIIGGTITATILAIFF
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEECCCCHHHHHHHHHHHHH
VPLFYVLVRRMFSRKTTVAKPLENTAPQAGE
HHHHHHHHHHHHHCCHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1720861; 8407802; 9278503 [H]