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The map label for this gene is ddpA [H]

Identifier: 157370587

GI number: 157370587

Start: 2558660

End: 2560210

Strand: Direct

Name: ddpA [H]

Synonym: Spro_2347

Alternate gene names: 157370587

Gene position: 2558660-2560210 (Clockwise)

Preceding gene: 157370586

Following gene: 157370588

Centisome position: 46.96

GC content: 57.12

Gene sequence:

>1551_bases
ATGAATCAGATCAAATACGCCGCTCTGGCGGCTGCAGTGACGTTGGGCATGGCGGTAATGGGTCAGGCGCAGGCCGCTGT
ACCCAAAGACATGCTGGTGATTGGCAAGGCGGCCGACCCGCAAACGCTGGATCCGGCGGTGACCATAGATAACAACGACT
GGACGGTGACCTATCCGGCCTACCAACGACTGGTACAGTACAAAACCGAGGGCGGCAAAGGCTCGACTCAGGTGGAGGGC
GAGCTGGCAGAAAGCTGGACGGCTTCTGACGATCAGCTGGTGTGGACCTTTAAACTCAAACCCGGCAACAAGTTTGATGA
TGGTTCGGACGTTAATGCCGAGGCGGTGAAGTGGTCGTTCGAACGCCTGATGAAAATTGGTCAGGGGCCTTCCGAAGCTT
TCCCGAAAGACTTGCAGGTGACGGCGGTGGATCCGCTAACCGTGCGGTTCACTCTGAAAACCCCGTTTGCACCGTTCCTG
TACACCCTGGCCAACGACGGGGCCGGTATTGTTAACCCGGCCATCGCCAAGGCTAATCCGGCGGACGAAGGTAAAGCCTG
GCTGGCGAACCACAGCGCCGGTTCCGGCCCGTACAAATTGGATCGTTGGCAAAAAGGCCAGCAGCTGGTGCTGGTACCGA
ATCCGCATTACAGCGGCGCCAAACCGGCCTTTAAGCGGGTAACGGTGAAAATCATCGGCGAAAGCGCCACCCGTCGTTTA
CAACTGACCCGTGGTGACCTGGATATTGCCGAATCCTTGCCGATCGACCAGCTTACGGCGTTGAAGAGCGAAAACAAGGT
GGCGGTCAATGAGTATCCGTCGCTGCGGGTGACCTACTTATATCTCAACAACGGCAAAGCGCCGCTGAATCAGGTTGATC
TGCGCCGCGCCATTTCCTACGCGGTGGATTACCAGGGCATGGTGAAGGGCATTCTCGGCGGTAACGGCAAACAGATGCGT
GGCCCGATCCCGGAAGGCATGTGGGGATACGACGCCACCGCGCAGCAATATAGCCAGAATGCGGACAAGGCCAAAGCAAC
ACTGGCGGCGGTGAAGGACAAACCGGCTTCGCTCAATTTCCTGTATTCGGTAAGCGACCCCAACTGGGAGGCGATAGCGC
TGTCGGTACAGGCCAGCCTGGCGACGGTGGGCATCAACGTCAAGCTGGAGAAACTGGCCAACGCCACCATGCGTGACCGT
ATCGGCCAGGGTAACTACGACATCGCCATCGGCAACTGGAGCCCGGACTTCGCCGACCCCTACATGTTCATGAACTACTG
GTTCGAATCCGACAAGAAAGGACTGCCGGGCAACCGTTCGTTCTACAGCGATCCGCAGGTGGATGCGCTGCTGAAGAAAG
CGGTAGCGGTGTCCGATCAGCAGGTGCGTACTGCCGATTACCAGGCGGCGCAGAAAATTGTCATCGACCAGGCGGCTTAT
GTTTATCTGTTCCAGAAAAACTATCAGGTGGCGATGAACAAAGAGGTGAAGGGCTTTGTATATAACCCGATGCTGGAGCA
GGTGTTCAACGTTGGGCAGATGAGCAAGTAA

Upstream 100 bases:

>100_bases
AGCTGCCCAACGCGGGCGAGTATCCGCTTTTGGCCGATCGCTTCGGCTGTTTTTCTTACGATTAAAACAACACACATTCA
ACGCATCAGGAGCTTTGTTT

Downstream 100 bases:

>100_bases
GTTGTTTGGCTATTTCAGACATCTAACAAAGCCGGTTATTAGGGAGAGCGTGCCGATGGGGTCGTAGCAGCTTTAGCTGC
CGGAGTGCCCCACGGTGCGC

Product: extracellular solute-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MNQIKYAALAAAVTLGMAVMGQAQAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPAYQRLVQYKTEGGKGSTQVEG
ELAESWTASDDQLVWTFKLKPGNKFDDGSDVNAEAVKWSFERLMKIGQGPSEAFPKDLQVTAVDPLTVRFTLKTPFAPFL
YTLANDGAGIVNPAIAKANPADEGKAWLANHSAGSGPYKLDRWQKGQQLVLVPNPHYSGAKPAFKRVTVKIIGESATRRL
QLTRGDLDIAESLPIDQLTALKSENKVAVNEYPSLRVTYLYLNNGKAPLNQVDLRRAISYAVDYQGMVKGILGGNGKQMR
GPIPEGMWGYDATAQQYSQNADKAKATLAAVKDKPASLNFLYSVSDPNWEAIALSVQASLATVGINVKLEKLANATMRDR
IGQGNYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYSDPQVDALLKKAVAVSDQQVRTADYQAAQKIVIDQAAY
VYLFQKNYQVAMNKEVKGFVYNPMLEQVFNVGQMSK

Sequences:

>Translated_516_residues
MNQIKYAALAAAVTLGMAVMGQAQAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPAYQRLVQYKTEGGKGSTQVEG
ELAESWTASDDQLVWTFKLKPGNKFDDGSDVNAEAVKWSFERLMKIGQGPSEAFPKDLQVTAVDPLTVRFTLKTPFAPFL
YTLANDGAGIVNPAIAKANPADEGKAWLANHSAGSGPYKLDRWQKGQQLVLVPNPHYSGAKPAFKRVTVKIIGESATRRL
QLTRGDLDIAESLPIDQLTALKSENKVAVNEYPSLRVTYLYLNNGKAPLNQVDLRRAISYAVDYQGMVKGILGGNGKQMR
GPIPEGMWGYDATAQQYSQNADKAKATLAAVKDKPASLNFLYSVSDPNWEAIALSVQASLATVGINVKLEKLANATMRDR
IGQGNYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYSDPQVDALLKKAVAVSDQQVRTADYQAAQKIVIDQAAY
VYLFQKNYQVAMNKEVKGFVYNPMLEQVFNVGQMSK
>Mature_516_residues
MNQIKYAALAAAVTLGMAVMGQAQAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPAYQRLVQYKTEGGKGSTQVEG
ELAESWTASDDQLVWTFKLKPGNKFDDGSDVNAEAVKWSFERLMKIGQGPSEAFPKDLQVTAVDPLTVRFTLKTPFAPFL
YTLANDGAGIVNPAIAKANPADEGKAWLANHSAGSGPYKLDRWQKGQQLVLVPNPHYSGAKPAFKRVTVKIIGESATRRL
QLTRGDLDIAESLPIDQLTALKSENKVAVNEYPSLRVTYLYLNNGKAPLNQVDLRRAISYAVDYQGMVKGILGGNGKQMR
GPIPEGMWGYDATAQQYSQNADKAKATLAAVKDKPASLNFLYSVSDPNWEAIALSVQASLATVGINVKLEKLANATMRDR
IGQGNYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYSDPQVDALLKKAVAVSDQQVRTADYQAAQKIVIDQAAY
VYLFQKNYQVAMNKEVKGFVYNPMLEQVFNVGQMSK

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=494, Percent_Identity=76.3157894736842, Blast_Score=785, Evalue=0.0,
Organism=Escherichia coli, GI1789966, Length=531, Percent_Identity=28.060263653484, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI87081878, Length=530, Percent_Identity=27.3584905660377, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787052, Length=506, Percent_Identity=26.6798418972332, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1787551, Length=448, Percent_Identity=25.4464285714286, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1787495, Length=530, Percent_Identity=25.8490566037736, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789887, Length=469, Percent_Identity=24.7334754797441, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789397, Length=541, Percent_Identity=24.5841035120148, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 56614; Mature: 56614

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQIKYAALAAAVTLGMAVMGQAQAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPA
CCCHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEECCCCCCCCCCEEEEECCCEEEECHH
YQRLVQYKTEGGKGSTQVEGELAESWTASDDQLVWTFKLKPGNKFDDGSDVNAEAVKWSF
HHHHHHHHCCCCCCCCEECCHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHH
ERLMKIGQGPSEAFPKDLQVTAVDPLTVRFTLKTPFAPFLYTLANDGAGIVNPAIAKANP
HHHHHHCCCCHHCCCCCCEEEEECCEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCC
ADEGKAWLANHSAGSGPYKLDRWQKGQQLVLVPNPHYSGAKPAFKRVTVKIIGESATRRL
CCCCCEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHEEEEEEECCCCCEEE
QLTRGDLDIAESLPIDQLTALKSENKVAVNEYPSLRVTYLYLNNGKAPLNQVDLRRAISY
EEECCCCCHHHCCCHHHHHHHCCCCCEEEECCCCEEEEEEEEECCCCCHHHHHHHHHHHH
AVDYQGMVKGILGGNGKQMRGPIPEGMWGYDATAQQYSQNADKAKATLAAVKDKPASLNF
HHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCEEE
LYSVSDPNWEAIALSVQASLATVGINVKLEKLANATMRDRIGQGNYDIAIGNWSPDFADP
EEEECCCCCEEEEEEEEEEEEEEEEEEEEHHHHCCHHHHHCCCCCEEEEECCCCCCCCCC
YMFMNYWFESDKKGLPGNRSFYSDPQVDALLKKAVAVSDQQVRTADYQAAQKIVIDQAAY
HHEEHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEE
VYLFQKNYQVAMNKEVKGFVYNPMLEQVFNVGQMSK
EEEEECCCEEEECCCCCCEEECHHHHHHHCCCCCCC
>Mature Secondary Structure
MNQIKYAALAAAVTLGMAVMGQAQAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPA
CCCHHHHHHHHHHHHHHHHHCCHHHCCCCCEEEEECCCCCCCCCCEEEEECCCEEEECHH
YQRLVQYKTEGGKGSTQVEGELAESWTASDDQLVWTFKLKPGNKFDDGSDVNAEAVKWSF
HHHHHHHHCCCCCCCCEECCHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHH
ERLMKIGQGPSEAFPKDLQVTAVDPLTVRFTLKTPFAPFLYTLANDGAGIVNPAIAKANP
HHHHHHCCCCHHCCCCCCEEEEECCEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCC
ADEGKAWLANHSAGSGPYKLDRWQKGQQLVLVPNPHYSGAKPAFKRVTVKIIGESATRRL
CCCCCEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHEEEEEEECCCCCEEE
QLTRGDLDIAESLPIDQLTALKSENKVAVNEYPSLRVTYLYLNNGKAPLNQVDLRRAISY
EEECCCCCHHHCCCHHHHHHHCCCCCEEEECCCCEEEEEEEEECCCCCHHHHHHHHHHHH
AVDYQGMVKGILGGNGKQMRGPIPEGMWGYDATAQQYSQNADKAKATLAAVKDKPASLNF
HHCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCCEEE
LYSVSDPNWEAIALSVQASLATVGINVKLEKLANATMRDRIGQGNYDIAIGNWSPDFADP
EEEECCCCCEEEEEEEEEEEEEEEEEEEEHHHHCCHHHHHCCCCCEEEEECCCCCCCCCC
YMFMNYWFESDKKGLPGNRSFYSDPQVDALLKKAVAVSDQQVRTADYQAAQKIVIDQAAY
HHEEHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEE
VYLFQKNYQVAMNKEVKGFVYNPMLEQVFNVGQMSK
EEEEECCCEEEECCCCCCEEECHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]