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The map label for this gene is ddpX [H]

Identifier: 157370586

GI number: 157370586

Start: 2558061

End: 2558624

Strand: Direct

Name: ddpX [H]

Synonym: Spro_2346

Alternate gene names: 157370586

Gene position: 2558061-2558624 (Clockwise)

Preceding gene: 157370585

Following gene: 157370587

Centisome position: 46.95

GC content: 60.11

Gene sequence:

>564_bases
ATGAGTGACAATGTAACGTTAGTCGATTTGACCGAAGCCTTTCCCGAGCTGCCTATCGACTTGAAATACGCCAGCGCCGA
CAACCTGACCGGCCGGGCGATTTATCTTGAGAGCCGCTGCCTGCTGCATCCCGACGCGGTGCAGGGATTAGGGCGCTGTT
TGCTGGCGGCGCGGTTGGCCGGTTTTTCCCTGCTGGTGTTCGACGCTTATCGGCCACAGCAGGCGCAGGCATTGTTGTGG
CAGGCGTGTCCGGATCCGCAATATGTCACCAGCACGCTAACCGGTTCGCACCACAGCCGGGGCGTGGCGATCGACGTGAC
GCTGCTGGATGCCGCCGGTGTGGCGCTGGATATGGGCACCGCCTTTGATGAGATGAGCGAAAGATCCCACCCGTTTTACC
CTGATTTCCCTCCGGAGGTGCAGCGCAACCGGCTGCTGCTGAATGCGGTGATGGCCGCCGGAGGTTTTCGCGCTATCGCC
AGCGAATGGTGGCATTTCGAGCTGCCCAACGCGGGCGAGTATCCGCTTTTGGCCGATCGCTTCGGCTGTTTTTCTTACGA
TTAA

Upstream 100 bases:

>100_bases
GCGCGGCGGTGGAGCAACGGCTGGCCAATAACCGCAGCCTGCAAAAAGAGCTGGGGCAATTTGAATCTTAATCACTATTT
AATCACTATGGGAAAACGCA

Downstream 100 bases:

>100_bases
AACAACACACATTCAACGCATCAGGAGCTTTGTTTATGAATCAGATCAAATACGCCGCTCTGGCGGCTGCAGTGACGTTG
GGCATGGCGGTAATGGGTCA

Product: D-alanyl-D-alanine dipeptidase

Products: NA

Alternate protein names: D-Ala-D-Ala dipeptidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSDNVTLVDLTEAFPELPIDLKYASADNLTGRAIYLESRCLLHPDAVQGLGRCLLAARLAGFSLLVFDAYRPQQAQALLW
QACPDPQYVTSTLTGSHHSRGVAIDVTLLDAAGVALDMGTAFDEMSERSHPFYPDFPPEVQRNRLLLNAVMAAGGFRAIA
SEWWHFELPNAGEYPLLADRFGCFSYD

Sequences:

>Translated_187_residues
MSDNVTLVDLTEAFPELPIDLKYASADNLTGRAIYLESRCLLHPDAVQGLGRCLLAARLAGFSLLVFDAYRPQQAQALLW
QACPDPQYVTSTLTGSHHSRGVAIDVTLLDAAGVALDMGTAFDEMSERSHPFYPDFPPEVQRNRLLLNAVMAAGGFRAIA
SEWWHFELPNAGEYPLLADRFGCFSYD
>Mature_186_residues
SDNVTLVDLTEAFPELPIDLKYASADNLTGRAIYLESRCLLHPDAVQGLGRCLLAARLAGFSLLVFDAYRPQQAQALLWQ
ACPDPQYVTSTLTGSHHSRGVAIDVTLLDAAGVALDMGTAFDEMSERSHPFYPDFPPEVQRNRLLLNAVMAAGGFRAIAS
EWWHFELPNAGEYPLLADRFGCFSYD

Specific function: Hydrolyzes D-Ala-D-Ala. May have a role in cell-wall turnover [H]

COG id: COG2173

COG function: function code M; D-alanyl-D-alanine dipeptidase

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M15D family [H]

Homologues:

Organism=Escherichia coli, GI1787763, Length=184, Percent_Identity=63.5869565217391, Blast_Score=261, Evalue=3e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009045
- InterPro:   IPR000755 [H]

Pfam domain/function: PF01427 Peptidase_M15 [H]

EC number: =3.4.13.22 [H]

Molecular weight: Translated: 20610; Mature: 20478

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNVTLVDLTEAFPELPIDLKYASADNLTGRAIYLESRCLLHPDAVQGLGRCLLAARLA
CCCCEEEEEHHHHCCCCCCEEEECCCCCCCCEEEEEECCEEECCHHHHHHHHHHHHHHHC
GFSLLVFDAYRPQQAQALLWQACPDPQYVTSTLTGSHHSRGVAIDVTLLDAAGVALDMGT
CCEEEEEECCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCEEEEEEEECCCCEEEECCC
AFDEMSERSHPFYPDFPPEVQRNRLLLNAVMAAGGFRAIASEWWHFELPNAGEYPLLADR
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCEEEECCCCCCCCEEHHC
FGCFSYD
CCCCCCC
>Mature Secondary Structure 
SDNVTLVDLTEAFPELPIDLKYASADNLTGRAIYLESRCLLHPDAVQGLGRCLLAARLA
CCCEEEEEHHHHCCCCCCEEEECCCCCCCCEEEEEECCEEECCHHHHHHHHHHHHHHHC
GFSLLVFDAYRPQQAQALLWQACPDPQYVTSTLTGSHHSRGVAIDVTLLDAAGVALDMGT
CCEEEEEECCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCCCEEEEEEEECCCCEEEECCC
AFDEMSERSHPFYPDFPPEVQRNRLLLNAVMAAGGFRAIASEWWHFELPNAGEYPLLADR
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCEEEECCCCCCCCEEHHC
FGCFSYD
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]