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The map label for this gene is malX [H]

Identifier: 157370510

GI number: 157370510

Start: 2471623

End: 2471847

Strand: Reverse

Name: malX [H]

Synonym: Spro_2270

Alternate gene names: 157370510

Gene position: 2471847-2471623 (Counterclockwise)

Preceding gene: 157370512

Following gene: 157370509

Centisome position: 45.36

GC content: 52.44

Gene sequence:

>225_bases
ATGCCAGCACCTAAAAAACAAAAAATCACGCTCTGGGAGTTTTTCCAGAGCCTGGGCAAAACATTCATGCTGCCCGTCGC
CTTGCTGTCGTTCTGCGGCATCATGCTGGGCATCGGCAGTTCGCTGAGCAGCCGCGATGTCATCACCCTGCTGCCGTTTA
TCGGCCACCCTGCTTTCCAGTTGCTGTTCACCTGGAAAGGATTGATTATAAAAGCATGGTCGTGA

Upstream 100 bases:

>100_bases
ATTAGCGGCGCATTTTTGCTAGGTAAAACGTTTTATCTTATTTTTACCTAACAGGGGTACACACCACCTTCGCACGTTTT
TTCGCCAGGAGCCGCCGGTT

Downstream 100 bases:

>100_bases
AGAATTGGTGCAAAGCAGACAAAAAGACAAAGCATTACCGCAAGAATGAATCTAGATGTTGCAGAATTGATTCAACTTGC
GGTAATTTTTTGCCCCATGC

Product: PTS system maltose and glucose-specific transporter subunit IIABC

Products: NA

Alternate protein names: Maltose and glucose permease IIC component; PTS system maltose- and glucose-specific EIIC component; Maltose- and glucose-specific phosphotransferase enzyme IIB component; PTS system maltose- and glucose-specific EIIB component [H]

Number of amino acids: Translated: 74; Mature: 73

Protein sequence:

>74_residues
MPAPKKQKITLWEFFQSLGKTFMLPVALLSFCGIMLGIGSSLSSRDVITLLPFIGHPAFQLLFTWKGLIIKAWS

Sequences:

>Translated_74_residues
MPAPKKQKITLWEFFQSLGKTFMLPVALLSFCGIMLGIGSSLSSRDVITLLPFIGHPAFQLLFTWKGLIIKAWS
>Mature_73_residues
PAPKKQKITLWEFFQSLGKTFMLPVALLSFCGIMLGIGSSLSSRDVITLLPFIGHPAFQLLFTWKGLIIKAWS

Specific function: MalX encodes a phosphotransferase system enzyme II that can recognize glucose and maltose as substrates even though these sugars may not represent the natural substrates of the system [H]

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=65, Percent_Identity=75.3846153846154, Blast_Score=103, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011301 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 8269; Mature: 8138

Theoretical pI: Translated: 10.80; Mature: 10.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPKKQKITLWEFFQSLGKTFMLPVALLSFCGIMLGIGSSLSSRDVITLLPFIGHPAFQ
CCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHH
LLFTWKGLIIKAWS
HHHHHCCCEEEECC
>Mature Secondary Structure 
PAPKKQKITLWEFFQSLGKTFMLPVALLSFCGIMLGIGSSLSSRDVITLLPFIGHPAFQ
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHH
LLFTWKGLIIKAWS
HHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1856179; 9097039; 9278503; 2670898 [H]