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The map label for this gene is sufC [H]

Identifier: 157370421

GI number: 157370421

Start: 2382336

End: 2383082

Strand: Direct

Name: sufC [H]

Synonym: Spro_2181

Alternate gene names: 157370421

Gene position: 2382336-2383082 (Clockwise)

Preceding gene: 157370420

Following gene: 157370422

Centisome position: 43.72

GC content: 53.95

Gene sequence:

>747_bases
ATGTTAAGTATCAAGAATTTAAAAGTCAGCGCGGAAGGCAACGAGATCCTCAAGGGCCTGGATCTGGAAATCAAACCGGG
CGAAGTGCATGCCATCATGGGGCCGAACGGCTCGGGCAAAAGCACGCTTTCTGCGACCCTGGCCGGGCGCGAAGAGTACG
AAGTGACCGCGGGCGAAGTGACCTTCAAAGGCAAGGATCTGCTTGAACTGGCACCGGAAGACCGTGCGGGTGAAGGGGTG
TTTCTGGCGTTCCAGTATCCGGTGGAGATCCCCGGCGTCAGCAACCATTTCTTCCTGCAGACCTCGGTTAATGCGGTGCG
TAAATATCGCGATCAGGAGCCGCTCGATCGCTTCGATTTTGCTGATTTTATCGAAGAAAAAATTGAGCTGTTGAATATGC
CGCCCGATCTGCTGACCCGTTCGGTTAACGTTGGCTTCTCCGGCGGCGAGAAAAAGCGTAATGACATCCTGCAGATGGCC
GCGCTGGAACCGGACCTGTGCATTCTGGATGAAACCGACTCCGGTTTGGATATTGATGCGCTGAAAATTGTTGCCAACGG
CGTTAACTCACTGCGGGACGGCAAGCGCTCGTTCATTATCGTCACGCACTACCAGCGCATTCTGGACTACATCAAACCGG
ATTACGTTCATGTTCTTTCTCAGGGGCGCATCGTCAAATCCGGCGATTTCACCCTGGTGAAACAGTTGGAGGAGCAGGGC
TATGGCTGGCTTACCGACGAGCAATAA

Upstream 100 bases:

>100_bases
GTTCGCCGTTGAGGCACAGAAGCTATTGGCCATCAGCCTGGAACACAGCGTGGGCTAATCGCCGGATTTACAGCGCGAAA
GCGCGACCTAAGGACACTGC

Downstream 100 bases:

>100_bases
TTCGCGCGCGCTGCAGCAACTCTACAGTCTGTTTGAAGCCCGCGGCGGCGAGCACTCCGCCCATGCGCTGGCACACTGGC
AACAGGCCTTGCGCCTGGGC

Product: cysteine desulfurase ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MLSIKNLKVSAEGNEILKGLDLEIKPGEVHAIMGPNGSGKSTLSATLAGREEYEVTAGEVTFKGKDLLELAPEDRAGEGV
FLAFQYPVEIPGVSNHFFLQTSVNAVRKYRDQEPLDRFDFADFIEEKIELLNMPPDLLTRSVNVGFSGGEKKRNDILQMA
ALEPDLCILDETDSGLDIDALKIVANGVNSLRDGKRSFIIVTHYQRILDYIKPDYVHVLSQGRIVKSGDFTLVKQLEEQG
YGWLTDEQ

Sequences:

>Translated_248_residues
MLSIKNLKVSAEGNEILKGLDLEIKPGEVHAIMGPNGSGKSTLSATLAGREEYEVTAGEVTFKGKDLLELAPEDRAGEGV
FLAFQYPVEIPGVSNHFFLQTSVNAVRKYRDQEPLDRFDFADFIEEKIELLNMPPDLLTRSVNVGFSGGEKKRNDILQMA
ALEPDLCILDETDSGLDIDALKIVANGVNSLRDGKRSFIIVTHYQRILDYIKPDYVHVLSQGRIVKSGDFTLVKQLEEQG
YGWLTDEQ
>Mature_248_residues
MLSIKNLKVSAEGNEILKGLDLEIKPGEVHAIMGPNGSGKSTLSATLAGREEYEVTAGEVTFKGKDLLELAPEDRAGEGV
FLAFQYPVEIPGVSNHFFLQTSVNAVRKYRDQEPLDRFDFADFIEEKIELLNMPPDLLTRSVNVGFSGGEKKRNDILQMA
ALEPDLCILDETDSGLDIDALKIVANGVNSLRDGKRSFIIVTHYQRILDYIKPDYVHVLSQGRIVKSGDFTLVKQLEEQG
YGWLTDEQ

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI255708477, Length=223, Percent_Identity=30.9417040358744, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI148612844, Length=223, Percent_Identity=30.9417040358744, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787972, Length=248, Percent_Identity=84.2741935483871, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1787370, Length=232, Percent_Identity=27.1551724137931, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1786698, Length=180, Percent_Identity=29.4444444444444, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787500, Length=216, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786345, Length=229, Percent_Identity=27.9475982532751, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI87081791, Length=177, Percent_Identity=29.9435028248588, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789593, Length=248, Percent_Identity=25, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787143, Length=234, Percent_Identity=24.7863247863248, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1789864, Length=242, Percent_Identity=25.2066115702479, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=236, Percent_Identity=28.3898305084746, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115533592, Length=220, Percent_Identity=28.1818181818182, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI212646699, Length=216, Percent_Identity=28.2407407407407, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71996809, Length=213, Percent_Identity=25.8215962441315, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=219, Percent_Identity=30.5936073059361, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193209708, Length=222, Percent_Identity=28.3783783783784, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17558664, Length=228, Percent_Identity=26.7543859649123, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17567265, Length=218, Percent_Identity=28.8990825688073, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27561; Mature: 27561

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSIKNLKVSAEGNEILKGLDLEIKPGEVHAIMGPNGSGKSTLSATLAGREEYEVTAGEV
CCCCCEEEEECCCCHHHHCCCCEECCCCEEEEECCCCCCCCEEEEEECCCCCEEEEECEE
TFKGKDLLELAPEDRAGEGVFLAFQYPVEIPGVSNHFFLQTSVNAVRKYRDQEPLDRFDF
EECCCHHEEECCCCCCCCEEEEEEECCEECCCCCCEEEEEEHHHHHHHHCCCCCCHHHHH
ADFIEEKIELLNMPPDLLTRSVNVGFSGGEKKRNDILQMAALEPDLCILDETDSGLDIDA
HHHHHHHHHHHCCCHHHHHEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHH
LKIVANGVNSLRDGKRSFIIVTHYQRILDYIKPDYVHVLSQGRIVKSGDFTLVKQLEEQG
HHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHCCHHEEHHCCCEEEECCCHHHHHHHHHCC
YGWLTDEQ
CCCCCCCC
>Mature Secondary Structure
MLSIKNLKVSAEGNEILKGLDLEIKPGEVHAIMGPNGSGKSTLSATLAGREEYEVTAGEV
CCCCCEEEEECCCCHHHHCCCCEECCCCEEEEECCCCCCCCEEEEEECCCCCEEEEECEE
TFKGKDLLELAPEDRAGEGVFLAFQYPVEIPGVSNHFFLQTSVNAVRKYRDQEPLDRFDF
EECCCHHEEECCCCCCCCEEEEEEECCEECCCCCCEEEEEEHHHHHHHHCCCCCCHHHHH
ADFIEEKIELLNMPPDLLTRSVNVGFSGGEKKRNDILQMAALEPDLCILDETDSGLDIDA
HHHHHHHHHHHCCCHHHHHEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHH
LKIVANGVNSLRDGKRSFIIVTHYQRILDYIKPDYVHVLSQGRIVKSGDFTLVKQLEEQG
HHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHCCHHEEHHCCCEEEECCCHHHHHHHHHCC
YGWLTDEQ
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]