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The map label for this gene is sufB [H]

Identifier: 157370420

GI number: 157370420

Start: 2380797

End: 2382293

Strand: Direct

Name: sufB [H]

Synonym: Spro_2180

Alternate gene names: 157370420

Gene position: 2380797-2382293 (Clockwise)

Preceding gene: 157370419

Following gene: 157370421

Centisome position: 43.69

GC content: 57.52

Gene sequence:

>1497_bases
ATGACACGAAGCAATGTAGAAATGCCTAATGAAGTGCAGGCTTGGGTCAGCGAAGGTCGCTACAAAGAAGGTTTTTTTAC
CCAGTTGGCCACCTATGAATTGGCGATGGGCATCAACGAAGACGTGGTGCGCGCTATCTCGGCCAAACGTAACGAACCTG
AGTGGATGCTGGAGTTCCGCCTGGAAGCCTACCGTGCCTGGCTGCAAATGGAAGAGCCACACTGGCTGAAGGCGAACTAC
GAGCGCCTGAACTATCAGGATTACAGCTATTACTCGGCGCCGTCCTGCGGCAGCTGTGATGACGCCTGCGGCTCGCAGCC
TGGCGCAGAACAGCAACCCGGCGCACCGACGGACAACAATTATCTGACCAGCGAGGTTGAACTGGCGTTTAACCAGCTCG
GTGTTCCGGTGCGTGAAGGCAGCGAAGTGGCAGTGGACGCTATCTTCGACTCGGTCTCGGTTTCGACCACCTACCGTGAA
AAGTTGGCGGAGAGCGGGGTGATTTTTTGCTCGTTCGGCGAAGCCATCCATGAATATCCGGATCTGGTGCGCGAATACCT
GGGTCGCGTAGTGCCGTCCAACGATAACTTCTTCGCCGCCTTGAATGCGGCGGTGGCCTCCGACGGCACCTTCGTTTACG
TGCCGAAGGGCGTGCGCTGTCCGATGGAACTGTCGACCTATTTCCGCATCAACGCCGCCAAAACCGGCCAGTTCGAGCGC
ACCATCCTGATCGCCGATGAAGGCAGCTATGTCAGCTATATCGAAGGCTGTTCGGCCCCGGTGCGTGACAGCTACCAGCT
GCACGCGGCGGTGGTGGAAGTGATCCTGCACAAAGACGCCGAAGTGAAATATTCGACGGTGCAGAACTGGTTCTCCGGCG
GTGACAGCAAGGGCGGTATCCTCAACTTCGTCACCAAGCGTGCGCTGTGTGAAGGCGCGGGTTCGAAAATGTCGTGGACC
CAGTCGGAAACCGGCTCGGCAATCACCTGGAAATACCCGAGCGTGATCCTGCAGGGCGACAATTCTATCGGTGAGTTCTT
CTCGGTGGCGCTGACCAGCGGCCATCAGCAGGCGGACACCGGTACCAAGATGATCCACATCGGCAAGAACACCCGTTCGA
CCATCATCGCCAAAGGCATCTCCGCCGGGCACAGCGAGAATACCTACCGCGGGCTGGTGAAGATCCTGCCGGGTGCGGAA
AACGCGCGTAACTTTACCCAGTGTGACTCGATGCTGATCGGGCCGGATAGCGGCGCTCATACCTTCCCGTATGTTGAAGC
CCGCAACAACAGTGCGCAGCTGGAACACGAGGCGACGACCTCAAAAATTGGTGATGACCAGCTGTTCTATTGTCTGCAGC
GTGGCATCAGCGAAGACAATGCCATTTCGATGATCGTCAACGGGTTCTGTAAGGACGTGTTCTCTGAGCTGCCGCTGGAG
TTCGCCGTTGAGGCACAGAAGCTATTGGCCATCAGCCTGGAACACAGCGTGGGCTAA

Upstream 100 bases:

>100_bases
TCCGTGAAGGGCTGAATCAGATATTCAAATTTAATAACCCTAAAGCTCAGCATGCCTGCGGTTGCGGCGAGAGTTTTGGC
GTTTGAGCGATGCAATCAAC

Downstream 100 bases:

>100_bases
TCGCCGGATTTACAGCGCGAAAGCGCGACCTAAGGACACTGCATGTTAAGTATCAAGAATTTAAAAGTCAGCGCGGAAGG
CAACGAGATCCTCAAGGGCC

Product: cysteine desulfurase activator complex subunit SufB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MTRSNVEMPNEVQAWVSEGRYKEGFFTQLATYELAMGINEDVVRAISAKRNEPEWMLEFRLEAYRAWLQMEEPHWLKANY
ERLNYQDYSYYSAPSCGSCDDACGSQPGAEQQPGAPTDNNYLTSEVELAFNQLGVPVREGSEVAVDAIFDSVSVSTTYRE
KLAESGVIFCSFGEAIHEYPDLVREYLGRVVPSNDNFFAALNAAVASDGTFVYVPKGVRCPMELSTYFRINAAKTGQFER
TILIADEGSYVSYIEGCSAPVRDSYQLHAAVVEVILHKDAEVKYSTVQNWFSGGDSKGGILNFVTKRALCEGAGSKMSWT
QSETGSAITWKYPSVILQGDNSIGEFFSVALTSGHQQADTGTKMIHIGKNTRSTIIAKGISAGHSENTYRGLVKILPGAE
NARNFTQCDSMLIGPDSGAHTFPYVEARNNSAQLEHEATTSKIGDDQLFYCLQRGISEDNAISMIVNGFCKDVFSELPLE
FAVEAQKLLAISLEHSVG

Sequences:

>Translated_498_residues
MTRSNVEMPNEVQAWVSEGRYKEGFFTQLATYELAMGINEDVVRAISAKRNEPEWMLEFRLEAYRAWLQMEEPHWLKANY
ERLNYQDYSYYSAPSCGSCDDACGSQPGAEQQPGAPTDNNYLTSEVELAFNQLGVPVREGSEVAVDAIFDSVSVSTTYRE
KLAESGVIFCSFGEAIHEYPDLVREYLGRVVPSNDNFFAALNAAVASDGTFVYVPKGVRCPMELSTYFRINAAKTGQFER
TILIADEGSYVSYIEGCSAPVRDSYQLHAAVVEVILHKDAEVKYSTVQNWFSGGDSKGGILNFVTKRALCEGAGSKMSWT
QSETGSAITWKYPSVILQGDNSIGEFFSVALTSGHQQADTGTKMIHIGKNTRSTIIAKGISAGHSENTYRGLVKILPGAE
NARNFTQCDSMLIGPDSGAHTFPYVEARNNSAQLEHEATTSKIGDDQLFYCLQRGISEDNAISMIVNGFCKDVFSELPLE
FAVEAQKLLAISLEHSVG
>Mature_497_residues
TRSNVEMPNEVQAWVSEGRYKEGFFTQLATYELAMGINEDVVRAISAKRNEPEWMLEFRLEAYRAWLQMEEPHWLKANYE
RLNYQDYSYYSAPSCGSCDDACGSQPGAEQQPGAPTDNNYLTSEVELAFNQLGVPVREGSEVAVDAIFDSVSVSTTYREK
LAESGVIFCSFGEAIHEYPDLVREYLGRVVPSNDNFFAALNAAVASDGTFVYVPKGVRCPMELSTYFRINAAKTGQFERT
ILIADEGSYVSYIEGCSAPVRDSYQLHAAVVEVILHKDAEVKYSTVQNWFSGGDSKGGILNFVTKRALCEGAGSKMSWTQ
SETGSAITWKYPSVILQGDNSIGEFFSVALTSGHQQADTGTKMIHIGKNTRSTIIAKGISAGHSENTYRGLVKILPGAEN
ARNFTQCDSMLIGPDSGAHTFPYVEARNNSAQLEHEATTSKIGDDQLFYCLQRGISEDNAISMIVNGFCKDVFSELPLEF
AVEAQKLLAISLEHSVG

Specific function: The sufBCD complex acts synergistically with sufE to stimulate the cysteine desulfurase activity of sufS. The sufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May facilitate iron uptake fro

COG id: COG0719

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, permease component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0051 (ycf24) family [H]

Homologues:

Organism=Escherichia coli, GI87081955, Length=499, Percent_Identity=84.1683366733467, Blast_Score=879, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010231
- InterPro:   IPR000825 [H]

Pfam domain/function: PF01458 UPF0051 [H]

EC number: NA

Molecular weight: Translated: 54871; Mature: 54740

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSNVEMPNEVQAWVSEGRYKEGFFTQLATYELAMGINEDVVRAISAKRNEPEWMLEFR
CCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHH
LEAYRAWLQMEEPHWLKANYERLNYQDYSYYSAPSCGSCDDACGSQPGAEQQPGAPTDNN
HHHHHHHHHCCCCCEEECCHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCC
YLTSEVELAFNQLGVPVREGSEVAVDAIFDSVSVSTTYREKLAESGVIFCSFGEAIHEYP
EEHHHHHHHHHHCCCCCCCCCCEEHHHHHHCCCCCHHHHHHHHHCCEEEEECCHHHHHHH
DLVREYLGRVVPSNDNFFAALNAAVASDGTFVYVPKGVRCPMELSTYFRINAAKTGQFER
HHHHHHHCCCCCCCCCEEEEEEHHHCCCCCEEEECCCCCCCCEECEEEEEEECCCCCCEE
TILIADEGSYVSYIEGCSAPVRDSYQLHAAVVEVILHKDAEVKYSTVQNWFSGGDSKGGI
EEEEECCCCEEHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCH
LNFVTKRALCEGAGSKMSWTQSETGSAITWKYPSVILQGDNSIGEFFSVALTSGHQQADT
HHHHHHHHHHHCCCCCCEECCCCCCCEEEEECCEEEEECCCCHHHHHHHHHHCCCCCCCC
GTKMIHIGKNTRSTIIAKGISAGHSENTYRGLVKILPGAENARNFTQCDSMLIGPDSGAH
CCEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHCCEEECCCCCCC
TFPYVEARNNSAQLEHEATTSKIGDDQLFYCLQRGISEDNAISMIVNGFCKDVFSELPLE
CCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHH
FAVEAQKLLAISLEHSVG
HHHHHHHHHEEEECCCCC
>Mature Secondary Structure 
TRSNVEMPNEVQAWVSEGRYKEGFFTQLATYELAMGINEDVVRAISAKRNEPEWMLEFR
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHH
LEAYRAWLQMEEPHWLKANYERLNYQDYSYYSAPSCGSCDDACGSQPGAEQQPGAPTDNN
HHHHHHHHHCCCCCEEECCHHHCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCC
YLTSEVELAFNQLGVPVREGSEVAVDAIFDSVSVSTTYREKLAESGVIFCSFGEAIHEYP
EEHHHHHHHHHHCCCCCCCCCCEEHHHHHHCCCCCHHHHHHHHHCCEEEEECCHHHHHHH
DLVREYLGRVVPSNDNFFAALNAAVASDGTFVYVPKGVRCPMELSTYFRINAAKTGQFER
HHHHHHHCCCCCCCCCEEEEEEHHHCCCCCEEEECCCCCCCCEECEEEEEEECCCCCCEE
TILIADEGSYVSYIEGCSAPVRDSYQLHAAVVEVILHKDAEVKYSTVQNWFSGGDSKGGI
EEEEECCCCEEHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCH
LNFVTKRALCEGAGSKMSWTQSETGSAITWKYPSVILQGDNSIGEFFSVALTSGHQQADT
HHHHHHHHHHHCCCCCCEECCCCCCCEEEEECCEEEEECCCCHHHHHHHHHHCCCCCCCC
GTKMIHIGKNTRSTIIAKGISAGHSENTYRGLVKILPGAENARNFTQCDSMLIGPDSGAH
CCEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHCCEEECCCCCCC
TFPYVEARNNSAQLEHEATTSKIGDDQLFYCLQRGISEDNAISMIVNGFCKDVFSELPLE
CCCEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHH
FAVEAQKLLAISLEHSVG
HHHHHHHHHEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]