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The map label for this gene is exoX [H]

Identifier: 157370180

GI number: 157370180

Start: 2123508

End: 2124176

Strand: Reverse

Name: exoX [H]

Synonym: Spro_1938

Alternate gene names: 157370180

Gene position: 2124176-2123508 (Counterclockwise)

Preceding gene: 157370183

Following gene: 157370172

Centisome position: 38.98

GC content: 53.06

Gene sequence:

>669_bases
ATGAATTTACGCGTAATAGACACTGAAACCTGCGGACTGGAAGGCGGCGTGGTAGAGGTGGCCTCTGTTGATCTGATCGA
CGGACAGATCGCCAACCCAATGAGCGATTTAATCAGCCCCGACCGCCCAATTGGCATTGAGGCCATGGCCATTCACCATA
TCACCGAGCAGATGGTCGAAGGGAAACCGCGCATCGCGGTAGCGATTGGTCGCTATCAGGGCAGTCCCTACTATGTCGCG
CACAATGCGGCATTCGATCGCGGCGTGTTACCAGAAATGCACGGCGCCTGGATCTGTACCATGAAACTGGCGCGCAACCT
GTACCCGGACATCAAATACGGCAACCAATATCTGCGCTATGCGCTGAATCTCGATGTTCAATTGCCGCAGGACACCACGC
TTTACCCACATCGGGCGTTATACGACTGCTACGTCACCGCCGCGCTATTGCAACGCATCATCAAGGATTCAGGTTGGACG
CCAGAACAGATGGCGCAAATTACTGACCAGCCAGTACTGCTGAAGAAGTTTAAGTTCGGTAAGTATCGTGGACAGGAAAT
TGATCGCGTCGCGCAGGAAGATCCCGGCTATTTGCGCTGGATGCTGAAATCTATCGAAGACCTCAGTCCGGACATGAAGC
ACACGCTGAAATACTATCTGATTGGTTGA

Upstream 100 bases:

>100_bases
GCGGGTTTTTTGTTGCCTGAAATAACGCTCCACCTTTCAGCGGTTGGCAGGAGCAAGGCTGCCGGTTAAGCTAAACCTGT
GCAGCCACTCTGAGGAAATC

Downstream 100 bases:

>100_bases
GAAAAGCGGGCAGCGCCAGCCGCCCGCCTGAAGGTTACTCCGCCAGCGCCAGAATAAAGGCGTACTCCAGCGCGATATCT
TCATAAGCTTTGAAACGCCC

Product: exodeoxyribonuclease X

Products: NA

Alternate protein names: Exodeoxyribonuclease X; Exo X; Exonuclease X [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MNLRVIDTETCGLEGGVVEVASVDLIDGQIANPMSDLISPDRPIGIEAMAIHHITEQMVEGKPRIAVAIGRYQGSPYYVA
HNAAFDRGVLPEMHGAWICTMKLARNLYPDIKYGNQYLRYALNLDVQLPQDTTLYPHRALYDCYVTAALLQRIIKDSGWT
PEQMAQITDQPVLLKKFKFGKYRGQEIDRVAQEDPGYLRWMLKSIEDLSPDMKHTLKYYLIG

Sequences:

>Translated_222_residues
MNLRVIDTETCGLEGGVVEVASVDLIDGQIANPMSDLISPDRPIGIEAMAIHHITEQMVEGKPRIAVAIGRYQGSPYYVA
HNAAFDRGVLPEMHGAWICTMKLARNLYPDIKYGNQYLRYALNLDVQLPQDTTLYPHRALYDCYVTAALLQRIIKDSGWT
PEQMAQITDQPVLLKKFKFGKYRGQEIDRVAQEDPGYLRWMLKSIEDLSPDMKHTLKYYLIG
>Mature_222_residues
MNLRVIDTETCGLEGGVVEVASVDLIDGQIANPMSDLISPDRPIGIEAMAIHHITEQMVEGKPRIAVAIGRYQGSPYYVA
HNAAFDRGVLPEMHGAWICTMKLARNLYPDIKYGNQYLRYALNLDVQLPQDTTLYPHRALYDCYVTAALLQRIIKDSGWT
PEQMAQITDQPVLLKKFKFGKYRGQEIDRVAQEDPGYLRWMLKSIEDLSPDMKHTLKYYLIG

Specific function: Capable of degrading both single-strand and double- strand DNA with 3' to 5' polarity. Has higher affinity for ssDNA ends than for dsDNA. May facilitate recombinational repair by pre- synaptic and/or post-synaptic DNA degradation [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788149, Length=218, Percent_Identity=61.4678899082569, Blast_Score=279, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: 3.1.11.- [C]

Molecular weight: Translated: 25203; Mature: 25203

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRVIDTETCGLEGGVVEVASVDLIDGQIANPMSDLISPDRPIGIEAMAIHHITEQMVE
CCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHC
GKPRIAVAIGRYQGSPYYVAHNAAFDRGVLPEMHGAWICTMKLARNLYPDIKYGNQYLRY
CCCEEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCEEEE
ALNLDVQLPQDTTLYPHRALYDCYVTAALLQRIIKDSGWTPEQMAQITDQPVLLKKFKFG
EEECEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHCC
KYRGQEIDRVAQEDPGYLRWMLKSIEDLSPDMKHTLKYYLIG
CCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHEECC
>Mature Secondary Structure
MNLRVIDTETCGLEGGVVEVASVDLIDGQIANPMSDLISPDRPIGIEAMAIHHITEQMVE
CCEEEEECCCCCCCCCEEEEEEEEEECCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHC
GKPRIAVAIGRYQGSPYYVAHNAAFDRGVLPEMHGAWICTMKLARNLYPDIKYGNQYLRY
CCCEEEEEEEEECCCCEEEEECCCCCCCCCCCCCCCEEHHHHHHHHCCCCCCCCCCEEEE
ALNLDVQLPQDTTLYPHRALYDCYVTAALLQRIIKDSGWTPEQMAQITDQPVLLKKFKFG
EEECEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCHHHHHHHCC
KYRGQEIDRVAQEDPGYLRWMLKSIEDLSPDMKHTLKYYLIG
CCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]