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The map label for this gene is holE [H]

Identifier: 157370183

GI number: 157370183

Start: 2126347

End: 2126577

Strand: Reverse

Name: holE [H]

Synonym: Spro_1941

Alternate gene names: 157370183

Gene position: 2126577-2126347 (Counterclockwise)

Preceding gene: 157370189

Following gene: 157370180

Centisome position: 39.03

GC content: 53.25

Gene sequence:

>231_bases
GTGGGTTACAATCTGGCAGAGCTTTCCAAAGAAGAGATGGACAAAGTGAACGTTGATCTCGCGGCTTCCGGCGTGGCATT
CAAAGAACGCTACAATATGCCGGTGATCCCGGAAATGGTTGAGCGTGAACAGCCGGCGCACCTGCGTGATTATTTCCGCG
AACGCGTAGCGCATTACCGCGTCGAATCACACAAGTTTTCACGCCTGCCGTACGAGCCGAAGTCCAAATAG

Upstream 100 bases:

>100_bases
CTTTGTCCTTAACTCCCCTTCTGCGCTTCAGGCTTGCCAAGCGCCGCCGGGTGCATTACCTTCTGCGCTGATCCAATGCG
GTAACTGTAAGGAGAATACG

Downstream 100 bases:

>100_bases
TAAAAAGCCCGCCGAGATGGCGGGCTCAGATTGCTGACAAAGTTCTTTGCGCTTAAAAGTCTTGATTTGGGGGCTAATAA
AAACAAAGGATTATGTCTTC

Product: DNA polymerase III subunit theta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 76; Mature: 75

Protein sequence:

>76_residues
MGYNLAELSKEEMDKVNVDLAASGVAFKERYNMPVIPEMVEREQPAHLRDYFRERVAHYRVESHKFSRLPYEPKSK

Sequences:

>Translated_76_residues
MGYNLAELSKEEMDKVNVDLAASGVAFKERYNMPVIPEMVEREQPAHLRDYFRERVAHYRVESHKFSRLPYEPKSK
>Mature_75_residues
GYNLAELSKEEMDKVNVDLAASGVAFKERYNMPVIPEMVEREQPAHLRDYFRERVAHYRVESHKFSRLPYEPKSK

Specific function: The exact function of the theta subunit is unknown [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788147, Length=76, Percent_Identity=71.0526315789474, Blast_Score=110, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009052
- InterPro:   IPR011325
- ProDom:   PD057609 [H]

Pfam domain/function: PF06440 DNA_pol3_theta [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 9015; Mature: 8884

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYNLAELSKEEMDKVNVDLAASGVAFKERYNMPVIPEMVEREQPAHLRDYFRERVAHYR
CCCCHHHHCHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHH
VESHKFSRLPYEPKSK
HHCCCCCCCCCCCCCC
>Mature Secondary Structure 
GYNLAELSKEEMDKVNVDLAASGVAFKERYNMPVIPEMVEREQPAHLRDYFRERVAHYR
CCCHHHHCHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHH
VESHKFSRLPYEPKSK
HHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]