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The map label for this gene is bepF [H]

Identifier: 157370172

GI number: 157370172

Start: 2113650

End: 2114816

Strand: Reverse

Name: bepF [H]

Synonym: Spro_1930

Alternate gene names: 157370172

Gene position: 2114816-2113650 (Counterclockwise)

Preceding gene: 157370180

Following gene: 157370171

Centisome position: 38.81

GC content: 59.55

Gene sequence:

>1167_bases
TTGTTCCATTCACGCCGTCGCCAAAGCGGCATCGGTATCAGCACTCGCCTCTCTGCCGTCGCGTTGCTGGTCGCTCTGCT
GGCCGGGTGTGACAACAGCGTCGCTCACAATGCGGCACCCCCGCCACCGGCCGTCAGCACCACCGACGTGGTGATAAAAC
CCATCAGCCAATGGGACGCTTTTAATGGTCGCATCGAGGCGGTGCAAAGCGTCCAGCTACGGCCACGGGTTTCCGGCTAT
ATCGATAAAGTGAATTACACCGAAGGCGATGAAGTGAAAAAAGGCCAGGTGCTGTTCACCATCGACGATCGTACCTACCG
CGCCGCTCGTGAGCAGGCCCAGGCCGAACTGGTTCGGGCACGCAATCAGGCAGCGCTGGCCCGCAGCGAATCCGGCCGTA
CCGAGAAACTGATCGGCAGCCAGGCAATATCGACTGAGGTGTGGGAACAACGCCGCTCCTCCGCCGCGCAGGCACAGAGC
AACGTATTGGCGGCTCAGGCCCAATTCGACCTGGCGCAACTGAACCTCGATTTTACCCGGGTGATCGCACCGATTGACGG
GCGTGCCAGCCGGGCAATGATCACCGCCGGCAACCTGGTGACCACCGGCGACAGTGCCAGCGTACTCACCACGCTGGTGT
CGCTCGACAAGGTTTACGTCTATTTCGACGTCGATGAAGCCACTTTTCTGCGTTACCAAAACGATGGGCGACGCACGGCA
AAACTGCCGGTGAAAGTCGGACTGGTCGGCGAAGACGGCTATCCGCATCAGGGCATCGTTGATTTTACCGACAACCAGCT
GAATGCCGGTACCGGCACCATCCGCATGCGCGCCCAGCTGGAAAACGCTGAGCGCCGCTTCACTCCAGGGCTATTCGCCC
GGGTGCAGATGCCCGGTAGCGCCGAGTTCAATGCCATGCTGATCAACGATAAATCGGTAATGACCGATCAGGATCGCAAG
TTTGTTTATATCGTCGATAAGGACGGCAAGGCGCAACGACGCGATATCGAAGTGGGCCGGGTGGCCGGTGGGCTACGTAT
TGTACAGAAGGGGCTGTCTGCCGGTGACCGGGTGATCGTCGACGGCATGCAAAAAGTGTTTATGCCGGGTATGCCGGTCG
CTGCCAAAAACGTGGCGATCAACGCCGACGCTTCCGCGCTTAACTAA

Upstream 100 bases:

>100_bases
GGTCACAGGCCAGGGAAGTTACCCGGATAACAGGGCCGGGTGTATCGCCAGATCGTGCTTACTACTGGAAAGAAAAATAA
TGCCAAGCCAGCCAAACTCA

Downstream 100 bases:

>100_bases
GCCCCAGTAAAGGATCCTGATCCATGGACTTTTCCCGTTTTTTCATCGACCGGCCGATATTTGCCGCGGTACTGTCGATT
CTGATTTTTGTCGGCGGTGT

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MFHSRRRQSGIGISTRLSAVALLVALLAGCDNSVAHNAAPPPPAVSTTDVVIKPISQWDAFNGRIEAVQSVQLRPRVSGY
IDKVNYTEGDEVKKGQVLFTIDDRTYRAAREQAQAELVRARNQAALARSESGRTEKLIGSQAISTEVWEQRRSSAAQAQS
NVLAAQAQFDLAQLNLDFTRVIAPIDGRASRAMITAGNLVTTGDSASVLTTLVSLDKVYVYFDVDEATFLRYQNDGRRTA
KLPVKVGLVGEDGYPHQGIVDFTDNQLNAGTGTIRMRAQLENAERRFTPGLFARVQMPGSAEFNAMLINDKSVMTDQDRK
FVYIVDKDGKAQRRDIEVGRVAGGLRIVQKGLSAGDRVIVDGMQKVFMPGMPVAAKNVAINADASALN

Sequences:

>Translated_388_residues
MFHSRRRQSGIGISTRLSAVALLVALLAGCDNSVAHNAAPPPPAVSTTDVVIKPISQWDAFNGRIEAVQSVQLRPRVSGY
IDKVNYTEGDEVKKGQVLFTIDDRTYRAAREQAQAELVRARNQAALARSESGRTEKLIGSQAISTEVWEQRRSSAAQAQS
NVLAAQAQFDLAQLNLDFTRVIAPIDGRASRAMITAGNLVTTGDSASVLTTLVSLDKVYVYFDVDEATFLRYQNDGRRTA
KLPVKVGLVGEDGYPHQGIVDFTDNQLNAGTGTIRMRAQLENAERRFTPGLFARVQMPGSAEFNAMLINDKSVMTDQDRK
FVYIVDKDGKAQRRDIEVGRVAGGLRIVQKGLSAGDRVIVDGMQKVFMPGMPVAAKNVAINADASALN
>Mature_388_residues
MFHSRRRQSGIGISTRLSAVALLVALLAGCDNSVAHNAAPPPPAVSTTDVVIKPISQWDAFNGRIEAVQSVQLRPRVSGY
IDKVNYTEGDEVKKGQVLFTIDDRTYRAAREQAQAELVRARNQAALARSESGRTEKLIGSQAISTEVWEQRRSSAAQAQS
NVLAAQAQFDLAQLNLDFTRVIAPIDGRASRAMITAGNLVTTGDSASVLTTLVSLDKVYVYFDVDEATFLRYQNDGRRTA
KLPVKVGLVGEDGYPHQGIVDFTDNQLNAGTGTIRMRAQLENAERRFTPGLFARVQMPGSAEFNAMLINDKSVMTDQDRK
FVYIVDKDGKAQRRDIEVGRVAGGLRIVQKGLSAGDRVIVDGMQKVFMPGMPVAAKNVAINADASALN

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786668, Length=381, Percent_Identity=33.8582677165354, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1789665, Length=367, Percent_Identity=32.9700272479564, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI1789929, Length=354, Percent_Identity=29.9435028248588, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI87082036, Length=306, Percent_Identity=28.1045751633987, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789637, Length=156, Percent_Identity=37.1794871794872, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87081796, Length=353, Percent_Identity=25.2124645892351, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081951, Length=177, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42181; Mature: 42181

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHSRRRQSGIGISTRLSAVALLVALLAGCDNSVAHNAAPPPPAVSTTDVVIKPISQWDA
CCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHEEEEHHHCCC
FNGRIEAVQSVQLRPRVSGYIDKVNYTEGDEVKKGQVLFTIDDRTYRAAREQAQAELVRA
CCCHHHHHHHEECCCCCCCCEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
RNQAALARSESGRTEKLIGSQAISTEVWEQRRSSAAQAQSNVLAAQAQFDLAQLNLDFTR
HHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCHHHCCCCEEE
VIAPIDGRASRAMITAGNLVTTGDSASVLTTLVSLDKVYVYFDVDEATFLRYQNDGRRTA
EEECCCCCCCEEEEEECCEEECCCCHHHHHHHHHHCEEEEEEECCCEEEEEECCCCCEEE
KLPVKVGLVGEDGYPHQGIVDFTDNQLNAGTGTIRMRAQLENAERRFTPGLFARVQMPGS
ECEEEEEEEECCCCCCCCEEECCCCCCCCCCCEEEEEEEECCHHHHCCCCEEEEEECCCC
AEFNAMLINDKSVMTDQDRKFVYIVDKDGKAQRRDIEVGRVAGGLRIVQKGLSAGDRVIV
CCEEEEEEECCCCCCCCCCEEEEEECCCCCCCHHCCHHHHHHHHHHHHHHHCCCCCEEEH
DGMQKVFMPGMPVAAKNVAINADASALN
HHHHHHHCCCCCEEECEEEEECCCCCCC
>Mature Secondary Structure
MFHSRRRQSGIGISTRLSAVALLVALLAGCDNSVAHNAAPPPPAVSTTDVVIKPISQWDA
CCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHEEEEHHHCCC
FNGRIEAVQSVQLRPRVSGYIDKVNYTEGDEVKKGQVLFTIDDRTYRAAREQAQAELVRA
CCCHHHHHHHEECCCCCCCCEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHH
RNQAALARSESGRTEKLIGSQAISTEVWEQRRSSAAQAQSNVLAAQAQFDLAQLNLDFTR
HHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCHHHCCCCEEE
VIAPIDGRASRAMITAGNLVTTGDSASVLTTLVSLDKVYVYFDVDEATFLRYQNDGRRTA
EEECCCCCCCEEEEEECCEEECCCCHHHHHHHHHHCEEEEEEECCCEEEEEECCCCCEEE
KLPVKVGLVGEDGYPHQGIVDFTDNQLNAGTGTIRMRAQLENAERRFTPGLFARVQMPGS
ECEEEEEEEECCCCCCCCEEECCCCCCCCCCCEEEEEEEECCHHHHCCCCEEEEEECCCC
AEFNAMLINDKSVMTDQDRKFVYIVDKDGKAQRRDIEVGRVAGGLRIVQKGLSAGDRVIV
CCEEEEEEECCCCCCCCCCEEEEEECCCCCCCHHCCHHHHHHHHHHHHHHHCCCCCEEEH
DGMQKVFMPGMPVAAKNVAINADASALN
HHHHHHHCCCCCEEECEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]